RU2014136336A - Чувствительный к стимулам материал и медицинский материал, содержащий его - Google Patents

Чувствительный к стимулам материал и медицинский материал, содержащий его Download PDF

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RU2014136336A
RU2014136336A RU2014136336A RU2014136336A RU2014136336A RU 2014136336 A RU2014136336 A RU 2014136336A RU 2014136336 A RU2014136336 A RU 2014136336A RU 2014136336 A RU2014136336 A RU 2014136336A RU 2014136336 A RU2014136336 A RU 2014136336A
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stimulus
sensitive material
fiber
sensitive
polymer
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RU2014136336A
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Томоюки ХОРИГУТИ
Косаку ТАКЕУТИ
Йосихиро НАРУСЕ
Кадзухиро ТАНАХАСИ
Макито ЙОКОЕ
Кохеи ЯМАСИТА
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Торэй Индастриз, Инк.
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    • A—HUMAN NECESSITIES
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
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    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
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    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0095—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
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    • C08J5/046—Reinforcing macromolecular compounds with loose or coherent fibrous material with synthetic macromolecular fibrous material
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    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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    • C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
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    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/06—Coatings containing a mixture of two or more compounds
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    • C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
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    • C08J2333/26—Homopolymers or copolymers of acrylamide or methacrylamide
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    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
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    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
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    • C08K3/00—Use of inorganic substances as compounding ingredients
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    • C—CHEMISTRY; METALLURGY
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    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/14—Polymer mixtures characterised by other features containing polymeric additives characterised by shape
    • C08L2205/16—Fibres; Fibrils
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/28—Formation of filaments, threads, or the like while mixing different spinning solutions or melts during the spinning operation; Spinnerette packs therefor
    • D01D5/30—Conjugate filaments; Spinnerette packs therefor
    • D01D5/36—Matrix structure; Spinnerette packs therefor
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
    • D01F6/90—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of polyamides
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
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    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
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    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
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Abstract

1. Чувствительный к стимулам материал, который отличается тем, что содержит чувствительный к стимулам полимер, волокна и воду, где волокна диспергируют в качестве имеющих среднечисловой диаметр от 1 до 900 нм.2. Чувствительный к стимулам материал по п. 1, где массовое отношение (чувствительный к стимулам полимер/волокно) чувствительного к стимулам полимера к волокну составляет от 5 до 100.3. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер представляет собой чувствительный к температуре полимер, который имеет нижнюю критическую температуру растворения.4. Чувствительный к стимулам материал по п. 1, где разность параметров растворимости основной химической структуры чувствительного к стимулам полимера и волокна составляет 0 до 5.5. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер и волокно имеют общую основную химическую структуру, выбранную из амидного звена, звена гидроксикислоты и моносахаридного звена.6. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер представляет собой полимер на основе поли(N-изопропилакриламида) и волокно представляет собой волокно на основе полиамида.7. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер содержит молочнокислое звено и волокно представляет собой полимолочную кислоту.8. Чувствительный к стимулам материал по п. 1, где волокно имеет длину волокна от 0,01 до 10,0 мм.9. Чувствительный к стимулам материал по п. 1, где отношение (L/D) длины волокна к диаметру волокна составляет 200 до 100000.10. Чувствительный к стимулам материал по п. 1, который дополнительно содержит поверхностно-активное вещество, которое имеет среднечислов

Claims (14)

1. Чувствительный к стимулам материал, который отличается тем, что содержит чувствительный к стимулам полимер, волокна и воду, где волокна диспергируют в качестве имеющих среднечисловой диаметр от 1 до 900 нм.
2. Чувствительный к стимулам материал по п. 1, где массовое отношение (чувствительный к стимулам полимер/волокно) чувствительного к стимулам полимера к волокну составляет от 5 до 100.
3. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер представляет собой чувствительный к температуре полимер, который имеет нижнюю критическую температуру растворения.
4. Чувствительный к стимулам материал по п. 1, где разность параметров растворимости основной химической структуры чувствительного к стимулам полимера и волокна составляет 0 до 5.
5. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер и волокно имеют общую основную химическую структуру, выбранную из амидного звена, звена гидроксикислоты и моносахаридного звена.
6. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер представляет собой полимер на основе поли(N-изопропилакриламида) и волокно представляет собой волокно на основе полиамида.
7. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам полимер содержит молочнокислое звено и волокно представляет собой полимолочную кислоту.
8. Чувствительный к стимулам материал по п. 1, где волокно имеет длину волокна от 0,01 до 10,0 мм.
9. Чувствительный к стимулам материал по п. 1, где отношение (L/D) длины волокна к диаметру волокна составляет 200 до 100000.
10. Чувствительный к стимулам материал по п. 1, который дополнительно содержит поверхностно-активное вещество, которое имеет среднечисловую молекулярную массу от 10000 до 100000.
11. Чувствительный к стимулам материал по п. 1, где чувствительный к стимулам материал представляет собой чувствительный к температуре материал, который имеет нижнюю критическую температуру растворения.
12. Чувствительный к стимулам материал по п. 1, где динамический модуль упругости составляет меньше чем 100 Па при 25ºC и максимальный динамический модуль упругости составляет от 100 до 50000 Па в пределах от 30 до 60ºC.
13. Медицинский материал, который содержит чувствительный к стимулам материал по любому из пп. 1-12.
14. Противоспаечный материал, который содержит чувствительный к стимулам материал по любому из пп. 1-12.
RU2014136336A 2012-02-08 2013-01-29 Чувствительный к стимулам материал и медицинский материал, содержащий его RU2625761C2 (ru)

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Application Number Priority Date Filing Date Title
JP2012024673 2012-02-08
JP2012-024673 2012-02-08
JP2012-024674 2012-02-08
JP2012024674 2012-02-08
JP2012-145164 2012-06-28
JP2012145164 2012-06-28
JP2012155262 2012-07-11
JP2012-155261 2012-07-11
JP2012-155262 2012-07-11
JP2012155261 2012-07-11
JP2012229573 2012-10-17
JP2012-229573 2012-10-17
PCT/JP2013/051813 WO2013118605A1 (ja) 2012-02-08 2013-01-29 刺激応答性材料およびそれを用いた医療材料

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WO2013118605A1 (ja) 2013-08-15
JP6090160B2 (ja) 2017-03-08
CA2861258C (en) 2019-08-20
ES2706149T3 (es) 2019-03-27
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