CA2858959A1 - Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation - Google Patents
Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation Download PDFInfo
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- CA2858959A1 CA2858959A1 CA2858959A CA2858959A CA2858959A1 CA 2858959 A1 CA2858959 A1 CA 2858959A1 CA 2858959 A CA2858959 A CA 2858959A CA 2858959 A CA2858959 A CA 2858959A CA 2858959 A1 CA2858959 A1 CA 2858959A1
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- Prior art keywords
- lipocalin mutein
- hepcidin
- iron
- mutein
- lipocalin
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Marine Sciences & Fisheries (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569501P | 2011-12-12 | 2011-12-12 | |
| US61/569,501 | 2011-12-12 | ||
| US201261599152P | 2012-02-15 | 2012-02-15 | |
| US61/599,152 | 2012-02-15 | ||
| PCT/EP2012/075135 WO2013087654A2 (en) | 2011-12-12 | 2012-12-12 | Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2858959A1 true CA2858959A1 (en) | 2013-06-20 |
Family
ID=47552958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2858959A Abandoned CA2858959A1 (en) | 2011-12-12 | 2012-12-12 | Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9610356B2 (OSRAM) |
| EP (2) | EP3309555A3 (OSRAM) |
| JP (2) | JP6305345B2 (OSRAM) |
| CN (1) | CN103998937A (OSRAM) |
| AU (1) | AU2012350654C1 (OSRAM) |
| CA (1) | CA2858959A1 (OSRAM) |
| DK (1) | DK2791684T3 (OSRAM) |
| SG (2) | SG10201604574UA (OSRAM) |
| WO (1) | WO2013087654A2 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168209A (zh) * | 2015-09-21 | 2015-12-23 | 浙江大学 | HDAC1抑制剂在制备调控hepcidin表达药物中的应用 |
| CN105726543A (zh) * | 2016-02-22 | 2016-07-06 | 浙江大学 | 腺嘌呤在制备调控hepcidin表达药物中的应用 |
| EP3438282A4 (en) | 2016-03-29 | 2020-05-06 | Advanced Telecommunications Research Institute International | METHOD FOR SCREENING CANDIDATE SUBSTANCES FOR AN ACTIVE COMPONENT TO PREVENT OR TREAT AT LEAST ONE SELECTED DISEASE IN THE KIDNEY HYPOFUNCTION GROUP, CHRONIC KIDNEY DISEASE AND KIDNEY DEFICIENCY |
| EP3504238A1 (en) * | 2016-08-29 | 2019-07-03 | Regeneron Pharmaceuticals, Inc. | Anti-gremlin-1 (grem1) antibodies and methods of use thereof for treating pulmonary arterial hypertension |
| AU2020253034A1 (en) * | 2019-03-29 | 2021-08-19 | Pieris Pharmaceuticals Gmbh | Inhaled administration of lipocalin muteins |
| KR20220088699A (ko) | 2019-09-27 | 2022-06-28 | 디스크 메디슨, 인크. | 골수섬유증 및 관련 상태의 치료 방법 |
| JP2023528223A (ja) | 2020-05-13 | 2023-07-04 | ディスク・メディシン・インコーポレイテッド | 骨髄線維症を処置するための抗ヘモジュベリン（ｈｊｖ）抗体 |
| WO2022098812A1 (en) | 2020-11-04 | 2022-05-12 | Keros Therapeutics, Inc. | Methods of treating iron overload |
| JP2023117892A (ja) * | 2022-02-14 | 2023-08-24 | 公益財団法人 鷹揚郷 | ヘプシジン結合ペプチド |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| DE19926068C1 (de) | 1999-06-08 | 2001-01-11 | Arne Skerra | Muteine des Bilin-Bindungsproteins |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| US7118915B2 (en) | 2001-09-27 | 2006-10-10 | Pieris Proteolab Ag | Muteins of apolipoprotein D |
| AU2003275958A1 (en) | 2003-08-25 | 2005-03-10 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| EP1996613B1 (en) * | 2006-03-20 | 2014-04-30 | Technische Universität München | Muteins of tear lipocalin with affinity for the t-cell coreceptor cd4 |
| WO2008011158A2 (en) | 2006-07-21 | 2008-01-24 | Amgen Inc. | Method of detecting and/ or measuring hepcidin in a sample |
| JP2010517529A (ja) | 2007-02-02 | 2010-05-27 | アムジエン・インコーポレーテツド | ヘプシジン及びヘプシジン抗体 |
| CL2008003190A1 (es) | 2007-11-02 | 2009-09-04 | Lilly Co Eli | Anticuerpo que se enlaza selectivamente a hepcidina-25 humana madura; polinucleotido codificante, vector y celula huesped que lo comprende; uso medico para tratar la anemia, incrementar nivel de hierro, conteo de rediculocito, celulas rojas, hemoglobina, o hematocritos; proceso de produccion; composicion farmaceutica. |
| EP2574628B1 (en) | 2008-01-25 | 2015-05-20 | Amgen Inc. | Ferroportin antibodies and methods of use |
| CA2722600C (en) | 2008-05-01 | 2014-01-21 | Amgen Inc. | Anti-hepcidin antibodies and methods of use |
| PT2328931E (pt) | 2008-08-06 | 2013-11-07 | Lilly Co Eli | Anticorpos selectivos anti-hepcidina-25 e utilizações dos mesmos |
| US20110268818A1 (en) * | 2008-09-18 | 2011-11-03 | Jonathan Barasch | Ngal-binding siderophores and use thereof to treat iron deficiency and iron overload |
| CN102365297B (zh) * | 2009-03-25 | 2014-10-29 | 霍夫曼-拉罗奇有限公司 | 新型抗-α5β1抗体及其应用 |
| CA2798713A1 (en) * | 2010-05-10 | 2011-11-17 | Intrinsic Lifesciences Llc | Markers for acute kidney injury |
| JP2013529907A (ja) * | 2010-05-24 | 2013-07-25 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | Ｎｇａｌタンパク質変異体及びその使用 |
| CA2808392C (en) * | 2010-08-16 | 2020-03-10 | Pieris Ag | Binding proteins for hepcidin |
-
2012
- 2012-12-12 EP EP17187016.5A patent/EP3309555A3/en not_active Withdrawn
- 2012-12-12 WO PCT/EP2012/075135 patent/WO2013087654A2/en not_active Ceased
- 2012-12-12 EP EP12813294.1A patent/EP2791684B1/en not_active Not-in-force
- 2012-12-12 SG SG10201604574UA patent/SG10201604574UA/en unknown
- 2012-12-12 US US14/364,465 patent/US9610356B2/en not_active Expired - Fee Related
- 2012-12-12 DK DK12813294.1T patent/DK2791684T3/da active
- 2012-12-12 JP JP2014546468A patent/JP6305345B2/ja not_active Expired - Fee Related
- 2012-12-12 CN CN201280061110.8A patent/CN103998937A/zh active Pending
- 2012-12-12 AU AU2012350654A patent/AU2012350654C1/en not_active Ceased
- 2012-12-12 CA CA2858959A patent/CA2858959A1/en not_active Abandoned
- 2012-12-12 SG SG11201402996WA patent/SG11201402996WA/en unknown
-
2017
- 2017-02-16 US US15/435,146 patent/US9950034B2/en not_active Expired - Fee Related
-
2018
- 2018-03-06 JP JP2018039343A patent/JP2018118980A/ja active Pending
- 2018-03-28 US US15/938,117 patent/US20180311311A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2791684A2 (en) | 2014-10-22 |
| AU2012350654C1 (en) | 2018-05-10 |
| AU2012350654B2 (en) | 2017-12-14 |
| JP2015501822A (ja) | 2015-01-19 |
| US20180311311A1 (en) | 2018-11-01 |
| EP3309555A2 (en) | 2018-04-18 |
| EP2791684B1 (en) | 2017-08-23 |
| WO2013087654A2 (en) | 2013-06-20 |
| JP2018118980A (ja) | 2018-08-02 |
| DK2791684T3 (da) | 2017-11-27 |
| US9610356B2 (en) | 2017-04-04 |
| SG11201402996WA (en) | 2014-07-30 |
| WO2013087654A3 (en) | 2013-09-12 |
| US9950034B2 (en) | 2018-04-24 |
| US20140323389A1 (en) | 2014-10-30 |
| CN103998937A (zh) | 2014-08-20 |
| JP6305345B2 (ja) | 2018-04-04 |
| US20170224770A1 (en) | 2017-08-10 |
| EP3309555A3 (en) | 2018-05-30 |
| SG10201604574UA (en) | 2016-07-28 |
| AU2012350654A1 (en) | 2014-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20171212 |
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| FZDE | Discontinued |
Effective date: 20210831 |
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| FZDE | Discontinued |
Effective date: 20210831 |