CA2857640C - Enhanced stem cell composition - Google Patents

Enhanced stem cell composition Download PDF

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Publication number
CA2857640C
CA2857640C CA2857640A CA2857640A CA2857640C CA 2857640 C CA2857640 C CA 2857640C CA 2857640 A CA2857640 A CA 2857640A CA 2857640 A CA2857640 A CA 2857640A CA 2857640 C CA2857640 C CA 2857640C
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cells
hematopoietic stem
pge2
disease
hours
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CA2857640A
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English (en)
French (fr)
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CA2857640A1 (en
Inventor
Dan Shoemaker
David Robbins
John D. Mendlein
Caroline Desponts
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
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CA2857640A 2011-12-02 2012-11-29 Enhanced stem cell composition Active CA2857640C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161566492P 2011-12-02 2011-12-02
US61/566,492 2011-12-02
PCT/US2012/066987 WO2013082243A1 (en) 2011-12-02 2012-11-29 Enhanced stem cell composition

Publications (2)

Publication Number Publication Date
CA2857640A1 CA2857640A1 (en) 2013-06-06
CA2857640C true CA2857640C (en) 2021-11-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2857640A Active CA2857640C (en) 2011-12-02 2012-11-29 Enhanced stem cell composition

Country Status (9)

Country Link
US (4) US9452186B2 (https=)
EP (2) EP3785767A1 (https=)
JP (7) JP6220791B2 (https=)
CN (3) CN112375734A (https=)
AU (1) AU2012321088B8 (https=)
CA (1) CA2857640C (https=)
ES (1) ES2836976T3 (https=)
PT (1) PT2785834T (https=)
WO (1) WO2013082243A1 (https=)

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US20180112180A1 (en) * 2015-01-26 2018-04-26 Fate Therapeutics, Inc. Cells with increased immuno-regulatory properties and methods for their use and manufacture
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RU2018106515A (ru) 2015-07-21 2019-08-21 Зе Чилдрен'С Медикал Сентер Корпорейшн Pd-l1-экспрессирующие гемопоэтические стволовые клетки и применения
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JP7595413B2 (ja) 2016-11-30 2024-12-06 ケース ウエスタン リザーブ ユニバーシティ １５－ｐｇｄｈ阻害剤とコルチコステロイドおよび／またはｔｎｆ阻害剤との組み合わせならびにその使用
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JP2021531288A (ja) 2018-07-22 2021-11-18 ミノヴィア セラピューティクス リミテッド 眼疾患のミトコンドリア増強療法
US12551504B2 (en) 2018-07-22 2026-02-17 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy of pancreatic diseases
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CN120463721A (zh) 2018-11-21 2025-08-12 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
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