AU2012321088B8 - Enhanced stem cell composition - Google Patents
Enhanced stem cell composition Download PDFInfo
- Publication number
- AU2012321088B8 AU2012321088B8 AU2012321088A AU2012321088A AU2012321088B8 AU 2012321088 B8 AU2012321088 B8 AU 2012321088B8 AU 2012321088 A AU2012321088 A AU 2012321088A AU 2012321088 A AU2012321088 A AU 2012321088A AU 2012321088 B8 AU2012321088 B8 AU 2012321088B8
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- Australia
- Prior art keywords
- cells
- hematopoietic stem
- pge2
- cell
- ischemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
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- Organic Chemistry (AREA)
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- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161566492P | 2011-12-02 | 2011-12-02 | |
| US61/566,492 | 2011-12-02 | ||
| PCT/US2012/066987 WO2013082243A1 (en) | 2011-12-02 | 2012-11-29 | Enhanced stem cell composition |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| AU2012321088A1 AU2012321088A1 (en) | 2013-06-20 |
| AU2012321088B2 AU2012321088B2 (en) | 2016-07-07 |
| AU2012321088A8 AU2012321088A8 (en) | 2016-12-15 |
| AU2012321088B8 true AU2012321088B8 (en) | 2016-12-15 |
Family
ID=48536037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012321088A Active AU2012321088B8 (en) | 2011-12-02 | 2012-11-29 | Enhanced stem cell composition |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9452186B2 (https=) |
| EP (2) | EP2785834B1 (https=) |
| JP (7) | JP6220791B2 (https=) |
| CN (3) | CN112410298A (https=) |
| AU (1) | AU2012321088B8 (https=) |
| CA (1) | CA2857640C (https=) |
| ES (1) | ES2836976T3 (https=) |
| PT (1) | PT2785834T (https=) |
| WO (1) | WO2013082243A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6220791B2 (ja) | 2011-12-02 | 2017-10-25 | フェイト セラピューティクス,インコーポレイテッド | 増強された幹細胞組成物 |
| EP2785350B1 (en) * | 2011-12-02 | 2018-05-02 | Fate Therapeutics, Inc. | Improved methods of treating ischemia |
| US9801863B2 (en) | 2012-04-16 | 2017-10-31 | Case Western Reserve University | Inhibitors of short-chain dehydrogenase activity for modulating hematopoietic stem cells and hematopoiesis |
| DK2838533T3 (da) | 2012-04-16 | 2017-11-27 | Univ Case Western Reserve | Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet |
| US9943545B2 (en) | 2013-03-15 | 2018-04-17 | Fate Therapeutics, Inc. | Stem cell culture media and methods of enhancing cell survival |
| WO2014150602A1 (en) * | 2013-03-15 | 2014-09-25 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
| AU2014342811B2 (en) | 2013-10-15 | 2019-01-03 | Board Of Regents Of The University Of Texas System | Compositions and methods of modulating short-chain dehydrogenase activity |
| AU2015217142B2 (en) * | 2014-02-12 | 2020-04-09 | 7 Hills Pharma LLC | Compositions and methods to improve the homing and grafting of hematopoetic stem cells |
| US20180112180A1 (en) * | 2015-01-26 | 2018-04-26 | Fate Therapeutics, Inc. | Cells with increased immuno-regulatory properties and methods for their use and manufacture |
| WO2016123100A1 (en) | 2015-01-26 | 2016-08-04 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| CN107921025A (zh) | 2015-03-08 | 2018-04-17 | 卡斯西部储备大学 | 用于治疗纤维症的短链脱氢酶活性的抑制剂 |
| US20180214487A1 (en) | 2015-07-21 | 2018-08-02 | The Children's Medical Center Corporation | Pd-l1 expressing hematopoietic stem cells and uses |
| WO2017059281A1 (en) * | 2015-10-02 | 2017-04-06 | Mcquillan Sharon Patrica | Adipose-derived stem cell product |
| KR20250141836A (ko) | 2015-11-04 | 2025-09-29 | 페이트 세러퓨틱스, 인코포레이티드 | 만능 세포의 유전자 조작 |
| SG11201803145RA (en) | 2015-11-04 | 2018-05-30 | Fate Therapeutics Inc | Methods and compositions for inducing hematopoietic cell differentiation |
| US11525119B2 (en) | 2016-09-06 | 2022-12-13 | The Children's Medical Center Corporation | Immune cells derived from induced pluripotent stem cell |
| WO2018070819A1 (ko) * | 2016-10-14 | 2018-04-19 | 제주대학교 산학협력단 | 시클레소나이드를 포함하는, 암 줄기세포 성장 억제용 조성물 |
| EP3548035A4 (en) | 2016-11-30 | 2020-07-22 | Case Western Reserve University | COMBINATIONS OF 15-PGDH INHIBITORS WITH CORCOSTEROIDS AND / OR TNF INHIBITORS AND THEIR USES |
| JP2020514323A (ja) | 2017-02-06 | 2020-05-21 | ケース ウエスタン リザーブ ユニバーシティ | 短鎖デヒドロゲナーゼ活性を調節する組成物と方法 |
| US11879137B2 (en) | 2017-09-22 | 2024-01-23 | The Children's Medical Center Corporation | Treatment of type 1 diabetes and autoimmune diseases or disorders |
| US11285177B2 (en) | 2018-01-03 | 2022-03-29 | Globus Medical, Inc. | Allografts containing viable cells and methods thereof |
| WO2020021535A1 (en) | 2018-07-22 | 2020-01-30 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy of ocular diseases |
| EP3823646A4 (en) | 2018-07-22 | 2022-06-08 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy of brain diseases |
| EP3823644A4 (en) | 2018-07-22 | 2022-06-08 | Minovia Therapeutics Ltd. | MITOCHONDRIAL AUGMENTATION THERAPY OF PANCREATIC DISEASES |
| JP7586811B2 (ja) | 2018-07-22 | 2024-11-19 | ミノヴィア セラピューティクス リミテッド | 腎臓疾患のミトコンドリア増強療法 |
| AU2019311859B2 (en) | 2018-07-22 | 2025-12-18 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy for primary mitochondrial diseases |
| KR102921276B1 (ko) | 2018-11-21 | 2026-02-03 | 케이스 웨스턴 리저브 유니버시티 | 단쇄 데히드로게나아제 활성을 조절하는 조성물 및 방법 |
| BR112022019609A2 (pt) | 2020-03-31 | 2022-11-29 | Minovia Therapeutics Ltd | Células geneticamente modificadas enriquecidas com mitocôndrias e usos das mesmas |
| CN113069460B (zh) * | 2021-03-24 | 2022-02-08 | 兰州大学 | 哈西奈德及其衍生物用于制备治疗和/或预防脑血管疾病药物中的应用 |
| CN114848675A (zh) * | 2022-06-24 | 2022-08-05 | 南开大学 | Pge2赋能的间充质干细胞制剂在制备治疗肺损伤药物中的应用 |
| GB202211232D0 (en) | 2022-08-02 | 2022-09-14 | Heptares Therapeutics Ltd | Prostaglandin EP4 receptor agonist compounds |
| WO2025155768A1 (en) * | 2024-01-17 | 2025-07-24 | Rhode Island Hospital | A motile injectable cell that accelerates musculoskeletal connective tissue repair |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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