CA2849823A1 - Microorganismes et procedes de production d'acrylate et autres produits a l'aide d'homoserine - Google Patents

Microorganismes et procedes de production d'acrylate et autres produits a l'aide d'homoserine Download PDF

Info

Publication number
CA2849823A1
CA2849823A1 CA2849823A CA2849823A CA2849823A1 CA 2849823 A1 CA2849823 A1 CA 2849823A1 CA 2849823 A CA2849823 A CA 2849823A CA 2849823 A CA2849823 A CA 2849823A CA 2849823 A1 CA2849823 A1 CA 2849823A1
Authority
CA
Canada
Prior art keywords
coa
seq
homoserine
amino acid
hydroxypropionyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2849823A
Other languages
English (en)
Inventor
Jun Xu
Charles Winston Saunders
Phillip Richard Green
Juan Esteban Velasquez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of CA2849823A1 publication Critical patent/CA2849823A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04002—Oxoglutarate dehydrogenase (succinyl-transferring) (1.2.4.2), i.e. alpha-ketoglutarat dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
    • C12Y104/01005—L-Amino-acid dehydrogenase (1.4.1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03002—L-Amino-acid oxidase (1.4.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03003—D-Amino-acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01072—Branched-chain-2-oxoacid decarboxylase (4.1.1.72)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2849823A 2011-10-05 2012-10-05 Microorganismes et procedes de production d'acrylate et autres produits a l'aide d'homoserine Abandoned CA2849823A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161543511P 2011-10-05 2011-10-05
US61/543,511 2011-10-05
PCT/US2012/058826 WO2013052717A2 (fr) 2011-10-05 2012-10-05 Microorganismes et procédés de production d'acrylate et autres produits à l'aide d'homosérine

Publications (1)

Publication Number Publication Date
CA2849823A1 true CA2849823A1 (fr) 2013-04-11

Family

ID=47116373

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2849823A Abandoned CA2849823A1 (fr) 2011-10-05 2012-10-05 Microorganismes et procedes de production d'acrylate et autres produits a l'aide d'homoserine

Country Status (5)

Country Link
EP (1) EP2764111A2 (fr)
CN (1) CN103890186A (fr)
AU (1) AU2012318597A1 (fr)
CA (1) CA2849823A1 (fr)
WO (1) WO2013052717A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102266181B1 (ko) 2013-09-03 2021-06-17 피티티 글로벌 케미컬 퍼블릭 컴퍼니 리미티드 1,3-프로판디올로부터 아크릴산, 아크릴로니트릴 및 1,4-부탄디올의 제조방법
EP2930244A1 (fr) * 2014-04-07 2015-10-14 The Procter and Gamble Company Micro-organismes et procédés de production d'acrylate et d'autres produits à partir d'homosérine
US20190233853A1 (en) * 2018-02-01 2019-08-01 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and/or derivatives thereof and/or compounds related thereto
CN110777127A (zh) * 2019-11-28 2020-02-11 江南大学 一种支链氨基酸转氨酶作为还原酶的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801058B1 (fr) 1999-11-16 2002-01-18 Roquette Freres Procede de purification du 1,3-propanediol a partir d'un milieu de fermentation
JP4780961B2 (ja) * 2002-05-10 2011-09-28 メタボリックス，インコーポレイテッド ２−ヒドロキシ酸モノマーを含む生体吸収性ポリマー
DE102005048818A1 (de) * 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
TWI456949B (zh) 2008-04-30 2014-10-11 Thomson Licensing 閘口裝置及其使用方法
BRPI0923748B1 (pt) * 2008-12-31 2019-04-09 Metabolic Explorer Método para a preparação de dióis
WO2010085731A2 (fr) 2009-01-23 2010-07-29 Microbia, Inc. Production de 1,4-butanediol dans un microorganisme
DE102009035091A1 (de) 2009-07-28 2011-02-10 Mahle International Gmbh Positionssensor und Linearaktuator
CA2781400A1 (fr) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production d'un acide organique, et/ou produits chimiques connexes

Also Published As

Publication number Publication date
WO2013052717A2 (fr) 2013-04-11
AU2012318597A2 (en) 2014-11-06
EP2764111A2 (fr) 2014-08-13
AU2012318597A1 (en) 2014-04-24
CN103890186A (zh) 2014-06-25
WO2013052717A3 (fr) 2013-06-13

Similar Documents

Publication Publication Date Title
US20240191216A1 (en) Recombinant host cells for the production of malonate
US8986961B2 (en) Fermentative production of acetone from renewable resources by means of novel metabolic pathway
JP5774493B2 (ja) ジオールの生産方法
KR102093172B1 (ko) 2,4-다이하이드록시부티레이트의 제조 방법
RU2626531C2 (ru) Способ получения 2,4-дигидроксимасляной кислоты
JP6342385B2 (ja) ２，４−ジヒドロキシ酪酸を生成する方法
WO2005118719A2 (fr) Production d'acide 3-hydroxypropionique au moyen de $g(b)-alanine/pyruvate aminotransferase
US11597951B2 (en) Method for preparation of diester derivatives of malonic acid
WO2012109534A2 (fr) Cellules et procédés de production d'acide isobutyrique
US20220380779A1 (en) Recombinant host cells for the production of malonate
US20140099676A1 (en) Microorganisms and methods for producing acrylate and other products from homoserine
CA2849823A1 (fr) Microorganismes et procedes de production d'acrylate et autres produits a l'aide d'homoserine
US20140296571A1 (en) Microorganisms And Methods For Producing Propionic Acid
KR20220021436A (ko) 고알칼리 조건에서 활성이 높은 신규 라이신 디카르복실라제 및 이를 이용한 카다베린 생산 방법
WO2013163292A2 (fr) Procédés et microorganismes pour augmenter la synthèse biologique d'alcanes bifonctionnels
US20140107377A1 (en) Microorganisms And Methods For Producing Acrylate And Other Products From Propionyl-CoA
CN111406104B (zh) 减少为了生产氨基酸或氨基酸衍生产物的亚胺/烯胺的积累
US11708564B2 (en) Microorganism expressing active D-proline reductase and method of producing active D-proline reductase
EP2930244A1 (fr) Micro-organismes et procédés de production d'acrylate et d'autres produits à partir d'homosérine
RU2811433C1 (ru) Новый полипептид и способ получения l-лейцина с его использованием
WO2022210228A1 (fr) SYNTHASE D'α-ISOPROPYLMALATE MODIFIÉE
CA3031318A1 (fr) Micro-organisme ayant une activite d'acyltransferase et son utilisation
WO2024054828A2 (fr) Cellules hôtes recombinées pour la production de malonate
CA3184703A1 (fr) Glutamate deshydrogenase modifiee et son utilisation
JP2023503218A (ja) アセトヒドロキシ酸シンターゼ新規変異体及びこれを含む微生物

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140321

FZDE Dead

Effective date: 20161005