CA2833660C - Filamentous fungi having an altered viscosity phenotype - Google Patents

Filamentous fungi having an altered viscosity phenotype Download PDF

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Publication number
CA2833660C
CA2833660C CA2833660A CA2833660A CA2833660C CA 2833660 C CA2833660 C CA 2833660C CA 2833660 A CA2833660 A CA 2833660A CA 2833660 A CA2833660 A CA 2833660A CA 2833660 C CA2833660 C CA 2833660C
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Prior art keywords
gene
strain
protein
variant
cells
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Active
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CA2833660A
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English (en)
French (fr)
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CA2833660A1 (en
Inventor
Elizabeth A. Bodie
Robert James Ii Pratt
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Danisco US Inc
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Danisco US Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07013Mannose-1-phosphate guanylyltransferase (2.7.7.13)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
CA2833660A 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype Active CA2833660C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161478160P 2011-04-22 2011-04-22
US201161478162P 2011-04-22 2011-04-22
US61/478,162 2011-04-22
US61/478,160 2011-04-22
PCT/US2012/034379 WO2012145584A1 (en) 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype

Publications (2)

Publication Number Publication Date
CA2833660A1 CA2833660A1 (en) 2012-10-26
CA2833660C true CA2833660C (en) 2020-08-04

Family

ID=46018123

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2833660A Active CA2833660C (en) 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype
CA2833541A Active CA2833541C (en) 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2833541A Active CA2833541C (en) 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype

Country Status (11)

Country Link
US (2) US9725727B2 (https=)
EP (3) EP3000870B1 (https=)
JP (2) JP6042866B2 (https=)
KR (2) KR101952470B1 (https=)
CN (2) CN103517916B (https=)
AR (2) AR086200A1 (https=)
AU (3) AU2012245402B2 (https=)
BR (2) BR112013025430A2 (https=)
CA (2) CA2833660C (https=)
DK (3) DK2663633T3 (https=)
WO (2) WO2012145595A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3000870B1 (en) * 2011-04-22 2018-01-24 Danisco US Inc. Filamentous fungi having an altered viscosity phenotype
CN103517981B (zh) 2011-04-22 2017-02-15 丹尼斯科美国公司 具有粘度改变表型的丝状真菌
EP3334751A1 (en) * 2015-08-13 2018-06-20 Glykos Finland Oy Regulatory protein deficient trichoderma cells and methods of use thereof
EP3755710A1 (en) 2018-04-24 2020-12-30 Danisco US Inc. Filamentous fungal strains comprising reduced viscosity phenotypes
JP7459509B2 (ja) * 2018-07-30 2024-04-02 東レ株式会社 トリコデルマ属糸状菌の変異株およびタンパク質の製造方法
JP2021532775A (ja) * 2018-07-30 2021-12-02 ダニスコ・ユーエス・インク タンパク質生産性が強化された表現型を含む突然変異及び遺伝子改変糸状菌株並びにそれらの方法
FI4055177T3 (fi) 2019-11-08 2024-10-31 Danisco Us Inc Parantuneen proteiinituottavuuden fenotyyppejä käsittäviä sienikantoja ja menetelmiä niitä varten
FR3104169B1 (fr) * 2019-12-04 2022-10-21 Ifp Energies Now Souche de champignon ayant une viscosite diminuee
CN113881586B (zh) * 2021-09-27 2023-03-10 四川大学 耐高温、耐高糖、耐高盐酿酒酵母菌株及构建方法和应用
CN118109437B (zh) * 2024-04-29 2024-07-09 北京中医药大学深圳医院(龙岗) 一种来自菌类中药的gdp-甘露糖焦磷酸化酶及其编码基因和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI972909A0 (fi) 1997-07-09 1997-07-09 Valtion Teknillinen Oekad produktion av avsoendrade proteiner genom rekombinatjaestceller
US7189538B2 (en) 1999-03-24 2007-03-13 Genencor International, Inc. Hyphal growth in fungi
KR20020059350A (ko) * 1999-07-30 2002-07-12 추후제출 재조합 단백질 생산용 숙주로서 아스페르길루스 소재의 용도
MXPA02010155A (es) 2000-04-13 2004-08-19 Mark Aaron Emalfarb Nuevas secuencias reguladoras de expresion y productos de expresion en el campo de hongos filamentosos.
AU2002303138A1 (en) * 2001-03-14 2002-10-15 Genencor International, Inc. Regulatable growth of filamentous fungi
AU2002305903A1 (en) * 2001-05-25 2002-12-09 Incyte Genomics Inc. Carbohydrate-associated proteins
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
EP1627049B1 (en) 2003-05-29 2010-02-17 Genencor International, Inc. Novel trichoderma genes
CA2699413C (en) 2007-09-11 2013-09-10 Cold Chain Technologies, Llc Insulated pallet shipper and methods of making and using the same
JP5435812B2 (ja) * 2008-03-07 2014-03-05 ダニスコ・ユーエス・インク トリコデルマ中でのカタラーゼの発現
CA2808777C (en) * 2010-08-25 2019-10-29 Danisco Us Inc. Filamentous fungi having an altered viscosity phenotype
EP3000870B1 (en) * 2011-04-22 2018-01-24 Danisco US Inc. Filamentous fungi having an altered viscosity phenotype
CN103517981B (zh) * 2011-04-22 2017-02-15 丹尼斯科美国公司 具有粘度改变表型的丝状真菌

Also Published As

Publication number Publication date
CA2833541A1 (en) 2012-10-26
AU2012245402B2 (en) 2017-09-28
KR20140033053A (ko) 2014-03-17
BR112013025203A2 (pt) 2016-11-29
DK3000870T3 (en) 2018-04-30
EP2663633A1 (en) 2013-11-20
US9725726B2 (en) 2017-08-08
DK2663633T3 (en) 2016-05-23
EP2663633B1 (en) 2016-02-24
AU2017202753A1 (en) 2017-05-18
CA2833660A1 (en) 2012-10-26
CN103502431A (zh) 2014-01-08
EP2699588B1 (en) 2016-11-30
AR086200A1 (es) 2013-11-27
CN103517916A (zh) 2014-01-15
CN103517916B (zh) 2017-05-10
US20140094587A1 (en) 2014-04-03
EP2699588A1 (en) 2014-02-26
AR086201A1 (es) 2013-11-27
BR112013025430A2 (pt) 2016-11-29
CN103502431B (zh) 2016-07-06
KR101993939B1 (ko) 2019-06-27
EP3000870B1 (en) 2018-01-24
JP6042868B2 (ja) 2016-12-14
JP2014513531A (ja) 2014-06-05
JP6042866B2 (ja) 2016-12-14
WO2012145584A1 (en) 2012-10-26
AU2012245322A1 (en) 2013-08-22
EP3000870A1 (en) 2016-03-30
JP2014513529A (ja) 2014-06-05
KR20140033048A (ko) 2014-03-17
AU2012245402A1 (en) 2013-08-22
US9725727B2 (en) 2017-08-08
KR101952470B1 (ko) 2019-02-26
CA2833541C (en) 2021-04-27
WO2012145595A1 (en) 2012-10-26
DK2699588T3 (en) 2017-03-13
US20140099721A1 (en) 2014-04-10

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