CA2831845C - System, device and method for ablation of a vessel's wall from the inside - Google Patents
System, device and method for ablation of a vessel's wall from the inside Download PDFInfo
- Publication number
- CA2831845C CA2831845C CA2831845A CA2831845A CA2831845C CA 2831845 C CA2831845 C CA 2831845C CA 2831845 A CA2831845 A CA 2831845A CA 2831845 A CA2831845 A CA 2831845A CA 2831845 C CA2831845 C CA 2831845C
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- implant
- ablation
- implant device
- vessel
- ablation region
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- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
Landscapes
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- Prostheses (AREA)
- Surgical Instruments (AREA)
- Magnetic Treatment Devices (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| IB2011051411 | 2011-04-01 | ||
| IBPCT/IB2011/051411 | 2011-04-01 | ||
| EPPCT/EP2011/058587 | 2011-05-25 | ||
| PCT/EP2011/058587 WO2012130337A1 (en) | 2011-04-01 | 2011-05-25 | System, device and method for ablation of a vessel's wall from the inside |
| PCT/EP2012/055999 WO2012131107A1 (en) | 2011-04-01 | 2012-04-02 | System, device and method for ablation of a vessel's wall from the inside |
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| CA2831845A1 CA2831845A1 (en) | 2012-10-04 |
| CA2831845C true CA2831845C (en) | 2020-03-10 |
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| CA2831845A Active CA2831845C (en) | 2011-04-01 | 2012-04-02 | System, device and method for ablation of a vessel's wall from the inside |
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Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6702811B2 (en) | 1999-04-05 | 2004-03-09 | Medtronic, Inc. | Ablation catheter assembly with radially decreasing helix and method of use |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US8774922B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods |
| WO2006063199A2 (en) | 2004-12-09 | 2006-06-15 | The Foundry, Inc. | Aortic valve repair |
| US9480552B2 (en) | 2006-04-26 | 2016-11-01 | The Cleveland Clinic Foundation | Apparatus and method for treating cardiovascular diseases |
| US9055946B2 (en) * | 2008-11-26 | 2015-06-16 | Phraxis Inc. | Anastomotic connector |
| EP3100696B1 (en) | 2010-10-25 | 2023-01-11 | Medtronic Ardian Luxembourg S.à.r.l. | Catheter apparatuses having multi-electrode arrays for renal neuromodulation |
| EP2694150A1 (en) | 2011-04-08 | 2014-02-12 | Covidien LP | Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery |
| TW201242570A (en) | 2011-04-25 | 2012-11-01 | Medtronic Ardian Luxembourg | Apparatus and methods related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls |
| US9526572B2 (en) | 2011-04-26 | 2016-12-27 | Aperiam Medical, Inc. | Method and device for treatment of hypertension and other maladies |
| EP2720622B1 (en) | 2011-06-15 | 2018-01-24 | Phraxis Inc. | Arterial venous spool anchor |
| EP2720626B1 (en) | 2011-06-15 | 2017-06-14 | Phraxis Inc. | Anastomotic connector and system for delivery |
| EP3181081B1 (en) | 2012-05-11 | 2022-05-04 | Medtronic Ireland Manufacturing Unlimited Company | Multi-electrode catheter assemblies for renal neuromodulation and associated systems |
| US10835366B2 (en) | 2012-08-16 | 2020-11-17 | Phraxis Inc. | Arterial and venous anchor devices forming an anastomotic connector and system for delivery |
| US8612022B1 (en) | 2012-09-13 | 2013-12-17 | Invatec S.P.A. | Neuromodulation catheters and associated systems and methods |
| US9095321B2 (en) | 2012-11-21 | 2015-08-04 | Medtronic Ardian Luxembourg S.A.R.L. | Cryotherapeutic devices having integral multi-helical balloons and methods of making the same |
| US9179974B2 (en) | 2013-03-15 | 2015-11-10 | Medtronic Ardian Luxembourg S.A.R.L. | Helical push wire electrode |
| US20150073515A1 (en) | 2013-09-09 | 2015-03-12 | Medtronic Ardian Luxembourg S.a.r.I. | Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods |
| US10219856B2 (en) * | 2013-09-30 | 2019-03-05 | Donald J. Geisel | Heated resonant cutting device and method of use thereof |
| US9579149B2 (en) | 2014-03-13 | 2017-02-28 | Medtronic Ardian Luxembourg S.A.R.L. | Low profile catheter assemblies and associated systems and methods |
| EP4371512A3 (en) | 2014-04-24 | 2024-08-14 | Medtronic Ardian Luxembourg S.à.r.l. | Neuromodulation catheters having braided shafts and associated systems and methods |
| US10709490B2 (en) | 2014-05-07 | 2020-07-14 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods |
| WO2016081611A1 (en) | 2014-11-19 | 2016-05-26 | Advanced Cardiac Therapeutics, Inc. | High-resolution mapping of tissue with pacing |
| SG11201703943VA (en) | 2014-11-19 | 2017-06-29 | Advanced Cardiac Therapeutics Inc | Ablation devices, systems and methods of using a high-resolution electrode assembly |
| US9956025B2 (en) * | 2014-12-05 | 2018-05-01 | Medtronic Cryocath Lp | Contrast agent to assess quality of occlusion through impedance measurement |
| US9636164B2 (en) | 2015-03-25 | 2017-05-02 | Advanced Cardiac Therapeutics, Inc. | Contact sensing systems and methods |
| US20170035358A1 (en) * | 2015-08-07 | 2017-02-09 | Boston Scientific Scimed Inc. | Force sensing catheters having super-elastic structural strain sensors |
| EP3362005B1 (en) | 2015-10-15 | 2020-12-16 | Medical Development Technologies S.A. | Improved implant device |
| AU2017212715B2 (en) | 2016-01-29 | 2019-08-08 | Boston Scientific Scimed, Inc. | Force sensing catheter with impedance-guided orientation |
| JP6923549B2 (ja) | 2016-03-15 | 2021-08-18 | エピックス セラピューティクス,インコーポレイテッド | 灌注式焼灼のための改良されたシステム |
| WO2017178077A1 (en) | 2016-04-15 | 2017-10-19 | Glenn Van Langenhove | Improved method and device for ablation |
| US11369431B2 (en) | 2016-06-11 | 2022-06-28 | Boston Scientific Scimed Inc. | Inductive double flat coil displacement sensor |
| KR20190029680A (ko) | 2016-07-14 | 2019-03-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 외부 금속 임플란트의 유도 가열을 위한 방법들, 장치들 및 시스템들 |
| EP3496640B1 (en) | 2016-08-12 | 2020-05-06 | Medical Development Technologies S.A. | Blood-flow interrupting means for insulating an implant device for ablation |
| CN108652734B (zh) * | 2017-03-27 | 2025-01-28 | 上海宏桐实业有限公司 | 用于心脏射频消融治疗的射频发生治疗装置 |
| WO2018193283A1 (en) | 2017-04-18 | 2018-10-25 | Glenn Van Langenhove | Improved device for ablation |
| CN110809448B (zh) | 2017-04-27 | 2022-11-25 | Epix疗法公司 | 确定导管尖端与组织之间接触的性质 |
| EP3727579B1 (en) | 2017-12-19 | 2021-10-06 | Medical Development Technologies S.A. | Heatable implant device for tumor treatment |
| US11000693B2 (en) * | 2018-02-20 | 2021-05-11 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
| JP7174207B2 (ja) * | 2018-09-10 | 2022-11-17 | 株式会社Flying Cell | 磁場誘導装置 |
| CN111110400B (zh) * | 2019-12-09 | 2022-02-22 | 先健科技(深圳)有限公司 | 心脏瓣膜系绳及具有其的心脏瓣膜组件 |
| CN111150439A (zh) * | 2020-03-05 | 2020-05-15 | 沈祥 | 一种腔镜甲状腺悬吊工具 |
| CN111759460B (zh) * | 2020-07-07 | 2021-05-11 | 杭州电子科技大学温州研究院有限公司 | 基于微型植入式自谐振线圈的热疗系统的参数优化方法 |
| EP4108197A1 (en) | 2021-06-24 | 2022-12-28 | Gradient Denervation Technologies | Systems for treating tissue |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5749914A (en) * | 1989-01-06 | 1998-05-12 | Advanced Coronary Intervention | Catheter for obstructed stent |
| JPH0663155A (ja) * | 1992-05-12 | 1994-03-08 | Riken Corp | ステント |
| US6283983B1 (en) * | 1995-10-13 | 2001-09-04 | Transvascular, Inc. | Percutaneous in-situ coronary bypass method and apparatus |
| US5830179A (en) * | 1996-04-09 | 1998-11-03 | Endocare, Inc. | Urological stent therapy system and method |
| US7235096B1 (en) * | 1998-08-25 | 2007-06-26 | Tricardia, Llc | Implantable device for promoting repair of a body lumen |
| GR1003340B (el) | 1999-02-15 | 2000-03-09 | Μεθοδος και διαταξη εξωτερικης αναιμακτης θερμανσης μεταλλικων ναρθηκων με την χρηση εναλλασσομενου μαγνητικου πεδιου | |
| US6632223B1 (en) | 2000-03-30 | 2003-10-14 | The General Hospital Corporation | Pulmonary vein ablation stent and method |
| US6981987B2 (en) | 1999-12-22 | 2006-01-03 | Ethicon, Inc. | Removable stent for body lumens |
| US6805695B2 (en) * | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
| US6802857B1 (en) | 2000-10-11 | 2004-10-12 | Uab Research Foundation | MRI stent |
| US6786918B1 (en) | 2000-10-17 | 2004-09-07 | Medtronic Vascular, Inc. | Stent delivery system |
| US6786904B2 (en) * | 2002-01-10 | 2004-09-07 | Triton Biosystems, Inc. | Method and device to treat vulnerable plaque |
| DE10113659B4 (de) * | 2001-03-21 | 2006-10-26 | Triton BioSystems Inc., Chelmsford | Metallischer medizinischer Stent |
| US7209783B2 (en) * | 2001-06-15 | 2007-04-24 | Cardiac Pacemakers, Inc. | Ablation stent for treating atrial fibrillation |
| EP1450711A1 (en) * | 2001-10-29 | 2004-09-01 | Triton Biosystems Inc. | Systems containing temperature regulated medical devices, and methods related thereto |
| US20040215310A1 (en) * | 2002-01-17 | 2004-10-28 | Omar Amirana | Stent and delivery method for applying RF energy to a pulmonary vein and the atrial wall around its ostium to eliminate atrial fibrillation while preventing stenosis of the pulmonary vein thereafter |
| US20060030914A1 (en) * | 2002-01-18 | 2006-02-09 | Apsara Medical Corporation | System, method and apparatus for evaluating tissue temperature |
| WO2003082403A2 (en) * | 2002-03-27 | 2003-10-09 | Cvrx, Inc. | Devices and methods for cardiovascular reflex control via coupled electrodes |
| US7620451B2 (en) * | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
| US20040106952A1 (en) * | 2002-12-03 | 2004-06-03 | Lafontaine Daniel M. | Treating arrhythmias by altering properties of tissue |
| US7195628B2 (en) * | 2002-12-11 | 2007-03-27 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Atrial fibrillation therapy with pulmonary vein support |
| WO2004073782A1 (en) * | 2003-02-19 | 2004-09-02 | Taewoong Medical Co., Ltd | Stent for high frequency thermotherapy |
| US7837676B2 (en) * | 2003-02-20 | 2010-11-23 | Recor Medical, Inc. | Cardiac ablation devices |
| US20040167506A1 (en) * | 2003-02-25 | 2004-08-26 | Scimed Life Systems, Inc. | Medical devices employing ferromagnetic heating |
| US7367970B2 (en) | 2003-11-11 | 2008-05-06 | Biosense Webster Inc. | Externally applied RF for pulmonary vein isolation |
| US7613523B2 (en) | 2003-12-11 | 2009-11-03 | Apsara Medical Corporation | Aesthetic thermal sculpting of skin |
| US8007495B2 (en) * | 2004-03-31 | 2011-08-30 | Biosense Webster, Inc. | Catheter for circumferential ablation at or near a pulmonary vein |
| US9011329B2 (en) * | 2004-04-19 | 2015-04-21 | Searete Llc | Lumenally-active device |
| CA2582160A1 (en) | 2004-10-08 | 2006-04-20 | Sinus Rhythm Technologies, Inc. | Two-stage scar generation for treating atrial fibrillation |
| CN100435763C (zh) * | 2005-11-04 | 2008-11-26 | 中国科学院理化技术研究所 | 结合热籽及血管支架实现血管内加热的肿瘤全身热疗装置 |
| ES2366046T3 (es) * | 2006-02-22 | 2011-10-14 | Custom Medical Applications, Inc. | Instrumento de ablación. |
| US8585753B2 (en) * | 2006-03-04 | 2013-11-19 | John James Scanlon | Fibrillated biodegradable prosthesis |
| US8170686B2 (en) * | 2006-03-14 | 2012-05-01 | Boston Scientific Scimed, Inc. | Heatable sling support for an anatomical location |
| CA2648277C (en) | 2006-04-04 | 2016-06-21 | University Health Network | A coil electrode apparatus for thermal therapy |
| GB0610489D0 (en) * | 2006-05-24 | 2006-07-05 | Emcision Ltd | Vessel closing device |
| US8460285B2 (en) * | 2006-12-29 | 2013-06-11 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation catheter electrode having multiple thermal sensors and method of use |
| US20080319247A1 (en) * | 2007-06-21 | 2008-12-25 | Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine | Method of local therapy using magnetizable thermoplastic implant |
| US20100225174A1 (en) | 2009-03-05 | 2010-09-09 | Hao Jiang | Wireless Power Transfer Using Magnets |
| US8512335B2 (en) | 2010-05-20 | 2013-08-20 | Curo Medical, Inc. | High frequency alternating current medical device with self-limiting conductive material and method |
| US8473067B2 (en) * | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
| EP2833968B1 (en) | 2012-04-02 | 2018-05-23 | Medical Development Technologies S.A. | Implant device and system for ablation of a vessel's wall from the inside |
| US9820799B2 (en) | 2012-04-02 | 2017-11-21 | Medical Development Technologies S.A. | Implant device and system for ablation of a renal arterial wall from the inside |
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| EA201301113A1 (ru) | 2015-01-30 |
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| AU2016244345B2 (en) | 2018-06-21 |
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| AU2016244345A1 (en) | 2016-11-03 |
| CN103561814B (zh) | 2017-07-07 |
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| BR112014024659B1 (pt) | 2021-12-28 |
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| US11020164B2 (en) | 2021-06-01 |
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| BR112013025173B1 (pt) | 2022-01-18 |
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