CA2825980C - Bifidobacterium bifidum strains for application in gastrointestinal diseases - Google Patents
Bifidobacterium bifidum strains for application in gastrointestinal diseases Download PDFInfo
- Publication number
- CA2825980C CA2825980C CA2825980A CA2825980A CA2825980C CA 2825980 C CA2825980 C CA 2825980C CA 2825980 A CA2825980 A CA 2825980A CA 2825980 A CA2825980 A CA 2825980A CA 2825980 C CA2825980 C CA 2825980C
- Authority
- CA
- Canada
- Prior art keywords
- strain
- cfu
- variant
- mutant
- bifidobacterium bifidum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11000744.0A EP2481299B1 (en) | 2011-01-31 | 2011-01-31 | Bifidobacterium bifidum strains for application in gastrointestinal diseases |
| EP11000744.0 | 2011-01-31 | ||
| PCT/EP2012/051369 WO2012104226A1 (en) | 2011-01-31 | 2012-01-27 | Bifidobacterium bifidum strains for application in gastrointestinal diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2825980A1 CA2825980A1 (en) | 2012-08-09 |
| CA2825980C true CA2825980C (en) | 2017-10-24 |
Family
ID=43901563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2825980A Active CA2825980C (en) | 2011-01-31 | 2012-01-27 | Bifidobacterium bifidum strains for application in gastrointestinal diseases |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9408879B2 (https=) |
| EP (1) | EP2481299B1 (https=) |
| JP (1) | JP5956467B2 (https=) |
| CN (1) | CN103476273A (https=) |
| AU (1) | AU2012213576B2 (https=) |
| BR (1) | BR112013019258B1 (https=) |
| CA (1) | CA2825980C (https=) |
| DK (1) | DK2481299T3 (https=) |
| ES (1) | ES2610908T3 (https=) |
| HR (1) | HRP20161792T1 (https=) |
| HU (1) | HUE033189T2 (https=) |
| PL (1) | PL2481299T3 (https=) |
| PT (1) | PT2481299T (https=) |
| RU (1) | RU2603285C2 (https=) |
| WO (1) | WO2012104226A1 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| CN103266076B (zh) * | 2013-06-04 | 2014-10-29 | 神舟太空产品高科技成果推广中心集团有限公司 | 太空诱变高效两歧双歧杆菌、其应用及其胶囊制剂的制备方法 |
| CN104546945A (zh) * | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 两歧双歧杆菌在治疗或预防类风湿性关节炎或其相关疾病中的用途 |
| SG11201704814SA (en) | 2014-12-23 | 2017-07-28 | 4D Pharma Res Ltd | Pirin polypeptide and immune modulation |
| WO2016102950A1 (en) | 2014-12-23 | 2016-06-30 | 4D Pharma Research Limited | Immune modulation |
| KR20180030459A (ko) * | 2015-03-09 | 2018-03-23 | 바이오이뮤나이저 에스에이지엘 | 항산화제와 비피도박테리아 및 프로바이오틱스로부터 분리된 세포벽이 조합된 조합물을 포함하는 항-노화 조성물 |
| WO2016203221A1 (en) | 2015-06-15 | 2016-12-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| ME03511B (me) | 2015-06-15 | 2020-04-20 | 4D Pharma Res Ltd | Kompozicije koje sadrže bakterijske sojeve |
| HRP20191949T1 (hr) | 2015-06-15 | 2020-01-24 | 4D Pharma Research Limited | Blautia stercosis i wexlerae za upotrebu u liječenju upalnih i autoimunih bolesti |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| JP6637725B2 (ja) * | 2015-10-28 | 2020-01-29 | ビオフェルミン製薬株式会社 | ウイルス感染症の予防及び/又は治療剤 |
| HK1254843B (zh) | 2015-11-20 | 2020-04-17 | 希杰生物科技株式会社 | 包含细菌菌株的组合物 |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| SG10201913557TA (en) | 2016-03-04 | 2020-02-27 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| ES2979098T3 (es) * | 2016-04-14 | 2024-09-24 | Int N&H Denmark Aps | Bifidobacterias para aumentar la masa corporal magra |
| TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| CN106579414A (zh) * | 2016-12-26 | 2017-04-26 | 北京康比特体育科技股份有限公司 | 一种缓解运动性腹泻的组合物 |
| CN106834187B (zh) * | 2017-03-06 | 2020-08-25 | 江南大学 | 一种两歧双歧杆菌及其用途 |
| US20180256505A1 (en) * | 2017-03-09 | 2018-09-13 | The Clorox Company | Probiotic capsule and methods of preparing the same |
| JP2018177703A (ja) * | 2017-04-14 | 2018-11-15 | 株式会社明治 | Toll様受容体2活性化用組成物 |
| ES2877726T3 (es) | 2017-05-22 | 2021-11-17 | 4D Pharma Res Ltd | Composiciones que comprenden cepas bacterianas |
| EP3630942B1 (en) | 2017-05-24 | 2022-11-30 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
| TWI812624B (zh) | 2017-06-14 | 2023-08-21 | 南韓商希杰生物科技股份有限公司 | 包含細菌品系之組成物 |
| ES2841902T3 (es) | 2017-06-14 | 2021-07-12 | 4D Pharma Res Ltd | Composiciones que comprenden cepas bacterianas |
| PL3600363T3 (pl) | 2017-06-14 | 2021-06-14 | 4D Pharma Research Limited | Kompozycje zawierające szczepy bakteryjne |
| WO2019145570A1 (en) * | 2018-01-29 | 2019-08-01 | Alimentary Health Limited | A combination product for prophylaxis and treatment of irritable bowel syndrome |
| KR102023700B1 (ko) * | 2018-01-31 | 2019-09-20 | 주식회사 비피도 | 비피도박테리움을 함유한 류마티스관절염 개선용, 치료용 또는 예방용 조성물 |
| CN112312920A (zh) * | 2018-06-22 | 2021-02-02 | 合成制剂有限公司 | 非存活两歧双歧杆菌及其用途 |
| CN112912088B (zh) * | 2019-01-16 | 2024-12-24 | N·V·努特里奇亚 | 用于轮状病毒引起的感染的具有非消化性寡糖的经发酵配方食品 |
| IT201900011193A1 (it) * | 2019-07-08 | 2021-01-08 | Sofar Spa | Ceppo di batteri Bifidobacterium bifidum, sue composizioni e relativi usi |
| BR112022004032A2 (pt) * | 2019-09-05 | 2022-05-24 | Superbrewed Food Inc | Composições probióticas mixotróficas e usos das mesmas no tratamento de distensão abdominal |
| IT201900016811A1 (it) * | 2019-09-20 | 2021-03-20 | Sofar Spa | Ceppi batterici, loro composizioni e loro uso per il trattamento di disturbi gastrointestinali |
| CN118924795A (zh) * | 2019-11-29 | 2024-11-12 | 内蒙古伊利实业集团股份有限公司 | 乳双歧杆菌bl-99提升肠道细菌感染抗性和肠道免疫力的应用 |
| CN111110704B (zh) * | 2020-02-14 | 2023-03-28 | 上海城建职业学院 | 一种益生菌菌剂、滴剂及其制备方法和应用 |
| CN111743998A (zh) * | 2020-06-04 | 2020-10-09 | 中通美雅生命健康(深圳)有限公司 | 用于辅助治疗肠炎组合物及其制备方法 |
| RU2735717C1 (ru) * | 2020-06-15 | 2020-11-06 | Общество с ограниченной ответственностью "АВАН" | Штамм Bifidobacterium bifidum, используемый в качестве пробиотика |
| JP2023542547A (ja) * | 2020-09-23 | 2023-10-10 | ピービーエルバイオラブ | 新規乳酸菌およびその用途 |
| CN113943682B (zh) * | 2020-11-12 | 2023-07-04 | 江南大学 | 缓解便秘的长双歧杆菌长亚种及其制备的发酵食品与益生菌制剂 |
| WO2022103638A1 (en) | 2020-11-16 | 2022-05-19 | Orcosa Inc. | Cannabinoids in the treatment of autism spectrum disorder |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| CN112980734B (zh) * | 2021-03-24 | 2022-07-22 | 江南大学 | 一株缓解便秘并调节肠道菌群紊乱的两歧双歧杆菌及其应用 |
| CN113025526B (zh) * | 2021-03-24 | 2022-09-27 | 江南大学 | 一株减少结肠病理损伤且具有缓解便秘作用的两歧双歧杆菌 |
| CN113234619B (zh) * | 2021-04-10 | 2022-07-05 | 江南大学 | 一株两歧双歧杆菌及其在缓解肠道损伤中的应用 |
| CN116004416B (zh) * | 2022-07-13 | 2024-05-10 | 四川大学 | 婴幼儿肠道来源的两歧双歧杆菌的应用 |
| CN116286439A (zh) * | 2022-07-13 | 2023-06-23 | 四川大学 | 一株婴幼儿肠道来源的两歧双歧杆菌及应用 |
| CN115838662A (zh) * | 2022-11-02 | 2023-03-24 | 江南大学 | 一株具有缓解克罗恩病潜力的两歧双歧杆菌 |
| EP4631511A4 (en) * | 2023-03-21 | 2026-04-22 | Sichuan Anaerobic Biotechnology Co Ltd | PROBIOTICS AND THEIR USE |
| CN118044616A (zh) * | 2023-09-05 | 2024-05-17 | 厦门大学 | 一种合生元及其用途 |
| WO2025059424A1 (en) * | 2023-09-15 | 2025-03-20 | Biohm Health Inc. | Pro-biotic compositions and methods for treatment of stress |
| CN118879582B (zh) * | 2024-09-19 | 2025-03-25 | 微康益生菌(苏州)股份有限公司 | 一种细胞完整、分散均匀、稳定性强的后生元制备方法 |
| CN121102165A (zh) * | 2025-11-13 | 2025-12-12 | 厦门承葛生物科技有限公司 | 用于精准肠道菌群移植的肠道菌群胶囊及其制备方法和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ID29150A (id) | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
| RU2152993C1 (ru) * | 1999-11-30 | 2000-07-20 | Государственный научный центр РФ Институт медико-биологических проблем | Штамм bifidobacterium bifidum вкпм ас-1578, используемый для приготовления бактериальных препаратов и продуктов питания |
| RU2184146C1 (ru) * | 2001-01-29 | 2002-06-27 | Закрытое акционерное общество "Партнер" | Штамм bifidobacterium bifidum 45 вкпм ас-1621, используемый для приготовления бактериальных препаратов и продуктов питания |
| ATE360682T1 (de) * | 2003-06-30 | 2007-05-15 | Clasado Inc | Neue galactooligosaccharidzusammensetzung und herstellung davon |
| CN101039687A (zh) * | 2004-08-05 | 2007-09-19 | 安尼德拉尔有限公司 | 产生叶酸的双岐杆菌菌株,及其制剂和应用 |
| AU2006253007B2 (en) * | 2005-05-31 | 2012-12-20 | Alimentary Health Ltd | Feline probiotic Bifidobacteria |
| CN100490826C (zh) * | 2005-07-05 | 2009-05-27 | 广州市微生物研究所 | 多联活性双歧杆菌产品的制备方法 |
| BRPI0616009A2 (pt) * | 2005-07-21 | 2011-05-31 | Yakult Honsha Kk | bactérias novas pertencentes ao gênero bifidobacterium e utilização das mesmas |
| US9084434B2 (en) * | 2006-09-27 | 2015-07-21 | Little Calumet Holdings Llc | Probiotic oral dosage forms |
| MX2009010187A (es) * | 2007-03-27 | 2009-10-19 | Procter & Gamble | Metodos y estuches para administracion de probioticos. |
| EP2270133B1 (en) * | 2008-04-22 | 2015-06-24 | Corporación Alimentaria Peñasanta (Capsa) | Method for obtaining a novel strain of bifidobacterium bifidum with activity against infection by helicobacter pylori |
| EP2280713A1 (en) * | 2008-05-01 | 2011-02-09 | The Procter & Gamble Company | Methods and kits for the treatment of inflammatory bowel disorder conditions |
| ES2656776T3 (es) * | 2008-06-13 | 2018-02-28 | N.V. Nutricia | Composición nutricional para bebés nacidos por cesárea |
-
2011
- 2011-01-31 PL PL11000744T patent/PL2481299T3/pl unknown
- 2011-01-31 EP EP11000744.0A patent/EP2481299B1/en active Active
- 2011-01-31 PT PT110007440T patent/PT2481299T/pt unknown
- 2011-01-31 ES ES11000744.0T patent/ES2610908T3/es active Active
- 2011-01-31 DK DK11000744.0T patent/DK2481299T3/en active
- 2011-01-31 HU HUE11000744A patent/HUE033189T2/en unknown
-
2012
- 2012-01-27 US US13/982,932 patent/US9408879B2/en active Active
- 2012-01-27 RU RU2013137404/10A patent/RU2603285C2/ru active
- 2012-01-27 AU AU2012213576A patent/AU2012213576B2/en active Active
- 2012-01-27 CA CA2825980A patent/CA2825980C/en active Active
- 2012-01-27 WO PCT/EP2012/051369 patent/WO2012104226A1/en not_active Ceased
- 2012-01-27 BR BR112013019258-5A patent/BR112013019258B1/pt active IP Right Grant
- 2012-01-27 CN CN2012800125218A patent/CN103476273A/zh active Pending
- 2012-01-27 JP JP2013550895A patent/JP5956467B2/ja active Active
-
2016
- 2016-12-28 HR HRP20161792TT patent/HRP20161792T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20161792T1 (hr) | 2017-03-10 |
| NZ613544A (en) | 2014-10-31 |
| PL2481299T3 (pl) | 2017-09-29 |
| RU2013137404A (ru) | 2015-03-10 |
| DK2481299T3 (en) | 2017-02-06 |
| JP5956467B2 (ja) | 2016-07-27 |
| US9408879B2 (en) | 2016-08-09 |
| EP2481299A1 (en) | 2012-08-01 |
| EP2481299B1 (en) | 2016-12-07 |
| WO2012104226A1 (en) | 2012-08-09 |
| JP2014505065A (ja) | 2014-02-27 |
| BR112013019258B1 (pt) | 2021-09-08 |
| PT2481299T (pt) | 2017-03-08 |
| ES2610908T3 (es) | 2017-05-04 |
| BR112013019258A2 (pt) | 2016-10-11 |
| HUE033189T2 (en) | 2017-11-28 |
| AU2012213576B2 (en) | 2015-07-23 |
| US20140056852A1 (en) | 2014-02-27 |
| CA2825980A1 (en) | 2012-08-09 |
| BR112013019258A8 (pt) | 2017-09-19 |
| CN103476273A (zh) | 2013-12-25 |
| RU2603285C2 (ru) | 2016-11-27 |
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