CA2818684C - Nk cell modulating treatments and methods for treatment of hematological malignancies - Google Patents

Nk cell modulating treatments and methods for treatment of hematological malignancies Download PDF

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Publication number
CA2818684C
CA2818684C CA2818684A CA2818684A CA2818684C CA 2818684 C CA2818684 C CA 2818684C CA 2818684 A CA2818684 A CA 2818684A CA 2818684 A CA2818684 A CA 2818684A CA 2818684 C CA2818684 C CA 2818684C
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Prior art keywords
antibody
antigen
binding fragment
seq
nkcir
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English (en)
French (fr)
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CA2818684A1 (en
Inventor
Pascale Andre
Renaud Buffet
Marcel Rozencweig
Jerome Tiollier
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Innate Pharma SA
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Innate Pharma SA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2818684A 2010-11-22 2011-11-22 Nk cell modulating treatments and methods for treatment of hematological malignancies Active CA2818684C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41597310P 2010-11-22 2010-11-22
US61/415,973 2010-11-22
PCT/US2011/061840 WO2012071411A2 (en) 2010-11-22 2011-11-22 Nk cell modulating treatments and methods for treatment of hematological malignancies

Publications (2)

Publication Number Publication Date
CA2818684A1 CA2818684A1 (en) 2012-05-31
CA2818684C true CA2818684C (en) 2023-02-21

Family

ID=46146390

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2818684A Active CA2818684C (en) 2010-11-22 2011-11-22 Nk cell modulating treatments and methods for treatment of hematological malignancies

Country Status (11)

Country Link
US (1) US9844593B2 (enExample)
EP (1) EP2643350A4 (enExample)
JP (2) JP6224457B2 (enExample)
CN (2) CN106963947A (enExample)
AR (1) AR083957A1 (enExample)
BR (1) BR112013012138B1 (enExample)
CA (1) CA2818684C (enExample)
EA (1) EA035033B1 (enExample)
MX (1) MX355483B (enExample)
TW (1) TWI664191B (enExample)
WO (1) WO2012071411A2 (enExample)

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Also Published As

Publication number Publication date
JP6224457B2 (ja) 2017-11-01
US20130251711A1 (en) 2013-09-26
CN106963947A (zh) 2017-07-21
BR112013012138B1 (pt) 2022-02-22
EP2643350A4 (en) 2015-01-07
EA201390756A1 (ru) 2014-11-28
JP2014501729A (ja) 2014-01-23
TW201305210A (zh) 2013-02-01
WO2012071411A3 (en) 2012-08-16
WO2012071411A2 (en) 2012-05-31
EA035033B1 (ru) 2020-04-20
CN103298831A (zh) 2013-09-11
MX2013005673A (es) 2013-12-06
MX355483B (es) 2018-04-19
AR083957A1 (es) 2013-04-10
CA2818684A1 (en) 2012-05-31
JP2016199549A (ja) 2016-12-01
BR112013012138A2 (pt) 2020-09-01
US9844593B2 (en) 2017-12-19
TWI664191B (zh) 2019-07-01
EP2643350A2 (en) 2013-10-02

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