JP6224457B2 - Nk細胞調節治療及び悪性血液疾患の治療方法 - Google Patents
Nk細胞調節治療及び悪性血液疾患の治療方法 Download PDFInfo
- Publication number
- JP6224457B2 JP6224457B2 JP2013541022A JP2013541022A JP6224457B2 JP 6224457 B2 JP6224457 B2 JP 6224457B2 JP 2013541022 A JP2013541022 A JP 2013541022A JP 2013541022 A JP2013541022 A JP 2013541022A JP 6224457 B2 JP6224457 B2 JP 6224457B2
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- Japan
- Prior art keywords
- antibody
- seq
- amino acid
- acid sequence
- kir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41597310P | 2010-11-22 | 2010-11-22 | |
| US61/415,973 | 2010-11-22 | ||
| PCT/US2011/061840 WO2012071411A2 (en) | 2010-11-22 | 2011-11-22 | Nk cell modulating treatments and methods for treatment of hematological malignancies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016095779A Division JP2016199549A (ja) | 2010-11-22 | 2016-05-12 | Nk細胞調節治療及び悪性血液疾患の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501729A JP2014501729A (ja) | 2014-01-23 |
| JP2014501729A5 JP2014501729A5 (enExample) | 2015-01-15 |
| JP6224457B2 true JP6224457B2 (ja) | 2017-11-01 |
Family
ID=46146390
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013541022A Expired - Fee Related JP6224457B2 (ja) | 2010-11-22 | 2011-11-22 | Nk細胞調節治療及び悪性血液疾患の治療方法 |
| JP2016095779A Pending JP2016199549A (ja) | 2010-11-22 | 2016-05-12 | Nk細胞調節治療及び悪性血液疾患の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016095779A Pending JP2016199549A (ja) | 2010-11-22 | 2016-05-12 | Nk細胞調節治療及び悪性血液疾患の治療方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9844593B2 (enExample) |
| EP (1) | EP2643350A4 (enExample) |
| JP (2) | JP6224457B2 (enExample) |
| CN (2) | CN106963947A (enExample) |
| AR (1) | AR083957A1 (enExample) |
| BR (1) | BR112013012138B1 (enExample) |
| CA (1) | CA2818684C (enExample) |
| EA (1) | EA035033B1 (enExample) |
| MX (1) | MX355483B (enExample) |
| TW (1) | TWI664191B (enExample) |
| WO (1) | WO2012071411A2 (enExample) |
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| US11471486B2 (en) | 2012-09-04 | 2022-10-18 | Inven2 As | Selective and controlled expansion of educated NK cells |
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| JP6856188B2 (ja) * | 2013-05-03 | 2021-04-07 | オハイオ・ステイト・イノベーション・ファウンデーション | Cs1特異的キメラ抗原受容体を遺伝子操作した免疫エフェクター細胞 |
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| WO2015195555A1 (en) * | 2014-06-16 | 2015-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Blocking cd38 using anti-cd38 antibody conjugated to protein g to protect nk cells |
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| EP3072522B1 (en) | 2005-01-06 | 2019-04-24 | Novo Nordisk A/S | Anti-kir combination treatments and methods |
| JP5295568B2 (ja) | 2005-01-06 | 2013-09-18 | ノヴォ ノルディスク アー/エス | Kir結合剤およびその使用方法 |
| AU2008204433B2 (en) | 2007-01-11 | 2014-03-13 | Novo Nordisk A/S | Anti-KIR antibodies, formulations, and uses thereof |
| US20100099084A1 (en) | 2008-10-17 | 2010-04-22 | Maher Albitar | Detection of npm1 nucleic acid in acellular body fluids |
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2011
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- 2011-11-22 CN CN201710194545.4A patent/CN106963947A/zh active Pending
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| US9844593B2 (en) | 2017-12-19 |
| EA035033B1 (ru) | 2020-04-20 |
| BR112013012138A2 (pt) | 2020-09-01 |
| EP2643350A4 (en) | 2015-01-07 |
| MX355483B (es) | 2018-04-19 |
| TWI664191B (zh) | 2019-07-01 |
| WO2012071411A2 (en) | 2012-05-31 |
| MX2013005673A (es) | 2013-12-06 |
| CN103298831A (zh) | 2013-09-11 |
| CA2818684C (en) | 2023-02-21 |
| EA201390756A1 (ru) | 2014-11-28 |
| AR083957A1 (es) | 2013-04-10 |
| BR112013012138B1 (pt) | 2022-02-22 |
| EP2643350A2 (en) | 2013-10-02 |
| JP2014501729A (ja) | 2014-01-23 |
| WO2012071411A3 (en) | 2012-08-16 |
| CN106963947A (zh) | 2017-07-21 |
| JP2016199549A (ja) | 2016-12-01 |
| US20130251711A1 (en) | 2013-09-26 |
| CA2818684A1 (en) | 2012-05-31 |
| TW201305210A (zh) | 2013-02-01 |
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