CA2818353A1 - Methods and compositions for inducing an immune response to egfrviii - Google Patents
Methods and compositions for inducing an immune response to egfrviii Download PDFInfo
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- CA2818353A1 CA2818353A1 CA2818353A CA2818353A CA2818353A1 CA 2818353 A1 CA2818353 A1 CA 2818353A1 CA 2818353 A CA2818353 A CA 2818353A CA 2818353 A CA2818353 A CA 2818353A CA 2818353 A1 CA2818353 A1 CA 2818353A1
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- acta
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- egfrviii
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001104—Epidermal growth factor receptors [EGFR]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
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- Molecular Biology (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US41485010P | 2010-11-17 | 2010-11-17 | |
| US61/414,850 | 2010-11-17 | ||
| PCT/US2011/061164 WO2012068360A1 (en) | 2010-11-17 | 2011-11-17 | Methods and compositions for inducing an immune response to egfrviii |
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| CA2818353A1 true CA2818353A1 (en) | 2012-05-24 |
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| CA2818353A Abandoned CA2818353A1 (en) | 2010-11-17 | 2011-11-17 | Methods and compositions for inducing an immune response to egfrviii |
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| EP (1) | EP2640842B1 (OSRAM) |
| JP (1) | JP5998370B2 (OSRAM) |
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| SI (1) | SI2640842T1 (OSRAM) |
| SM (1) | SMT201800444T1 (OSRAM) |
| WO (1) | WO2012068360A1 (OSRAM) |
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| CN103429606A (zh) | 2010-10-01 | 2013-12-04 | 现代治疗公司 | 设计核酸及其使用方法 |
| SI2640842T1 (sl) * | 2010-11-17 | 2018-09-28 | Aduro Biotech, Inc. | Postopki in sestavki za induciranje imunskega odziva na EGFRvIII |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| KR20190099538A (ko) | 2011-10-03 | 2019-08-27 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도 |
| EP4144378A1 (en) | 2011-12-16 | 2023-03-08 | ModernaTX, Inc. | Modified nucleoside, nucleotide, and nucleic acid compositions |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| SG11201407875UA (en) | 2012-06-08 | 2014-12-30 | Aduro Biotech | Compostions and methods for cancer immunotherapy |
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| DK2922554T3 (en) | 2012-11-26 | 2022-05-23 | Modernatx Inc | Terminalt modificeret rna |
| AU2013358892B2 (en) | 2012-12-13 | 2018-06-21 | Aduro Biotech, Inc. | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
| MX2015008329A (es) | 2012-12-27 | 2016-03-01 | Aduro Biotech Inc | Compañeros de fusion de peptido, señal que facilita la expresion listeral de secuencias antigenicas y metodos de preparacion y uso de los mismos. |
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| JP2016518140A (ja) | 2013-05-03 | 2016-06-23 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Ｉ型インターフェロンの環状ジヌクレオチド誘導法 |
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| BR112016007255A2 (pt) | 2013-10-03 | 2017-09-12 | Moderna Therapeutics Inc | polinucleotídeos que codificam receptor de lipoproteína de baixa densidade |
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| MA42263A (fr) * | 2015-06-24 | 2021-03-31 | Advaxis Inc | Dispositif de fabrication et procédé pour immunothérapie fondée sur un vecteur d'administration personnalisé |
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| NL2017267B1 (en) | 2016-07-29 | 2018-02-01 | Aduro Biotech Holdings Europe B V | Anti-pd-1 antibodies |
| WO2018026717A1 (en) * | 2016-08-01 | 2018-02-08 | Aduro Biotech, Inc. | Protein expression enhancer sequences and use thereof |
| NL2017270B1 (en) | 2016-08-02 | 2018-02-09 | Aduro Biotech Holdings Europe B V | New anti-hCTLA-4 antibodies |
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| WO2021014398A1 (en) * | 2019-07-23 | 2021-01-28 | University Of Rijeka Faculty Of Medicine | Integrated human cytomegalovirus / glioblastoma vaccine |
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| US5830702A (en) | 1990-10-31 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response |
| US5571702A (en) | 1991-03-29 | 1996-11-05 | Genentech, Inc. | Amplification method for detection of human PF4A receptors |
| IT1262895B (it) | 1992-03-02 | 1996-07-22 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. | |
| US6379943B1 (en) | 1999-03-05 | 2002-04-30 | Merck & Co., Inc. | High-efficiency Cre/loxp based system for construction of adenovirus vectors |
| US5709999A (en) * | 1994-08-12 | 1998-01-20 | Myriad Genetics Inc. | Linked breast and ovarian cancer susceptibility gene |
| US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US6051237A (en) | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| ATE262586T1 (de) * | 1994-11-28 | 2004-04-15 | Univ Jefferson | Fusion junction typ iii mutant egf rezeptor peptid-tumorvakzin |
| US5888530A (en) | 1995-07-21 | 1999-03-30 | The General Hospital Corporation | Method of enhancing delivery of a pharmaceutical formulation |
| US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
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| EP1513924A4 (en) | 2002-05-29 | 2008-05-21 | Univ California | ATTENUATED LISTERIA SPP. AND METHOD OF USE THEREOF |
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| US7833775B2 (en) | 2003-02-06 | 2010-11-16 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| MX2008005640A (es) * | 2005-11-02 | 2008-12-09 | Univ Duke | Quimioterapia e inmunoterapia concurrentes. |
| JP5347135B2 (ja) * | 2006-03-01 | 2013-11-20 | アドゥロ バイオテック | 遺伝子工学操作されたｌｉｓｔｅｒｉａおよびその使用方法 |
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| US8900816B2 (en) * | 2007-07-19 | 2014-12-02 | Duke University | Assay for anti-EGFRvIII antibodies |
| EP2283112B1 (en) | 2008-05-19 | 2016-10-12 | Aduro Biotech | Compositions comprising prfa*mutant listeria and methods of use thereof |
| AU2009273949A1 (en) * | 2008-07-24 | 2010-01-28 | Aduro Biotech | Compositions and methods for the treatment of hepatitis C |
| TWI543767B (zh) * | 2008-08-19 | 2016-08-01 | 腫瘤療法 科學股份有限公司 | Ｈｉｇ２與ｕｒｌｃ１０抗原決定位胜肽以及含此胜肽之疫苗 |
| SI2640842T1 (sl) * | 2010-11-17 | 2018-09-28 | Aduro Biotech, Inc. | Postopki in sestavki za induciranje imunskega odziva na EGFRvIII |
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2011
- 2011-11-17 SI SI201131548T patent/SI2640842T1/sl unknown
- 2011-11-17 RS RS20180979A patent/RS57630B1/sr unknown
- 2011-11-17 WO PCT/US2011/061164 patent/WO2012068360A1/en not_active Ceased
- 2011-11-17 HU HUE11841347A patent/HUE039747T2/hu unknown
- 2011-11-17 ES ES11841347.5T patent/ES2684684T3/es active Active
- 2011-11-17 EP EP11841347.5A patent/EP2640842B1/en active Active
- 2011-11-17 DK DK11841347.5T patent/DK2640842T3/en active
- 2011-11-17 SM SM20180444T patent/SMT201800444T1/it unknown
- 2011-11-17 HR HRP20181343TT patent/HRP20181343T1/hr unknown
- 2011-11-17 US US13/988,076 patent/US9200057B2/en not_active Expired - Fee Related
- 2011-11-17 PL PL11841347T patent/PL2640842T3/pl unknown
- 2011-11-17 JP JP2013540008A patent/JP5998370B2/ja not_active Expired - Fee Related
- 2011-11-17 LT LTEP11841347.5T patent/LT2640842T/lt unknown
- 2011-11-17 CA CA2818353A patent/CA2818353A1/en not_active Abandoned
- 2011-11-17 CN CN201180062129.XA patent/CN103415620B/zh not_active Expired - Fee Related
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2018
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Also Published As
| Publication number | Publication date |
|---|---|
| CN103415620B (zh) | 2016-10-12 |
| SI2640842T1 (sl) | 2018-09-28 |
| US20140037662A1 (en) | 2014-02-06 |
| US20160074491A1 (en) | 2016-03-17 |
| CY1120622T1 (el) | 2019-12-11 |
| LT2640842T (lt) | 2018-09-10 |
| PL2640842T3 (pl) | 2018-11-30 |
| US20180021420A1 (en) | 2018-01-25 |
| RS57630B1 (sr) | 2018-11-30 |
| EP2640842A1 (en) | 2013-09-25 |
| EP2640842B1 (en) | 2018-05-30 |
| US9200057B2 (en) | 2015-12-01 |
| HRP20181343T1 (hr) | 2018-10-19 |
| US9775891B2 (en) | 2017-10-03 |
| JP2014504851A (ja) | 2014-02-27 |
| DK2640842T3 (en) | 2018-08-13 |
| EP2640842A4 (en) | 2014-04-09 |
| JP5998370B2 (ja) | 2016-09-28 |
| HUE039747T2 (hu) | 2019-02-28 |
| CN103415620A (zh) | 2013-11-27 |
| ES2684684T3 (es) | 2018-10-04 |
| WO2012068360A1 (en) | 2012-05-24 |
| SMT201800444T1 (it) | 2018-09-13 |
| PT2640842T (pt) | 2018-10-12 |
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| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20161017 |
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| FZDE | Discontinued |
Effective date: 20200228 |