PL2640842T3 - Sposoby i kompozycje do indukowania odpowiedzi immunologicznej na EGFRVIII - Google Patents

Sposoby i kompozycje do indukowania odpowiedzi immunologicznej na EGFRVIII

Info

Publication number
PL2640842T3
PL2640842T3 PL11841347T PL11841347T PL2640842T3 PL 2640842 T3 PL2640842 T3 PL 2640842T3 PL 11841347 T PL11841347 T PL 11841347T PL 11841347 T PL11841347 T PL 11841347T PL 2640842 T3 PL2640842 T3 PL 2640842T3
Authority
PL
Poland
Prior art keywords
egfrviii
inducing
compositions
methods
immune response
Prior art date
Application number
PL11841347T
Other languages
English (en)
Inventor
Peter M. Lauer
Keith Bahjat
Original Assignee
Aduro Biotech, Inc.
Providence Health & Services-Oregon D/B/A Providence Portland Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aduro Biotech, Inc., Providence Health & Services-Oregon D/B/A Providence Portland Medical Center filed Critical Aduro Biotech, Inc.
Publication of PL2640842T3 publication Critical patent/PL2640842T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001104—Epidermal growth factor receptors [EGFR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL11841347T 2010-11-17 2011-11-17 Sposoby i kompozycje do indukowania odpowiedzi immunologicznej na EGFRVIII PL2640842T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41485010P 2010-11-17 2010-11-17
EP11841347.5A EP2640842B1 (en) 2010-11-17 2011-11-17 Methods and compositions for inducing an immune response to egfrviii
PCT/US2011/061164 WO2012068360A1 (en) 2010-11-17 2011-11-17 Methods and compositions for inducing an immune response to egfrviii

Publications (1)

Publication Number Publication Date
PL2640842T3 true PL2640842T3 (pl) 2018-11-30

Family

ID=46084412

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11841347T PL2640842T3 (pl) 2010-11-17 2011-11-17 Sposoby i kompozycje do indukowania odpowiedzi immunologicznej na EGFRVIII

Country Status (16)

Country Link
US (3) US9200057B2 (pl)
EP (1) EP2640842B1 (pl)
JP (1) JP5998370B2 (pl)
CN (1) CN103415620B (pl)
CA (1) CA2818353A1 (pl)
CY (1) CY1120622T1 (pl)
DK (1) DK2640842T3 (pl)
ES (1) ES2684684T3 (pl)
HR (1) HRP20181343T1 (pl)
HU (1) HUE039747T2 (pl)
LT (1) LT2640842T (pl)
PL (1) PL2640842T3 (pl)
PT (1) PT2640842T (pl)
RS (1) RS57630B1 (pl)
SI (1) SI2640842T1 (pl)
WO (1) WO2012068360A1 (pl)

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LT2640842T (lt) * 2010-11-17 2018-09-10 Aduro Biotech, Inc. Būdai ir kompozicijos, skirti indukuoti imuninį atsaką į egfrviii
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
HUE057725T2 (hu) 2011-10-03 2022-06-28 Modernatx Inc Módosított nukleozidok, nukleotidok és nukleinsavak és ezek felhasználása
HRP20220717T1 (hr) 2011-12-16 2022-07-22 Modernatx, Inc. Modificirani pripravci mrna
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
AU2013243947A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
KR20150022996A (ko) 2012-06-08 2015-03-04 아두로 바이오테크 암 면역요법을 위한 조성물 및 방법
AU2013341242B2 (en) 2012-11-06 2018-06-28 Aduro Biotech, Inc. Facultatively attenuated bacterial species and methods of preparation and use thereof
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
CN105008381B (zh) 2012-12-13 2018-08-07 艾杜罗生物科技公司 包含具有确定立体化学的环嘌呤二核苷酸的组合物及其制备和使用方法
WO2014106123A1 (en) 2012-12-27 2014-07-03 Aduro Biotech, Inc. Signal peptide fusion partners facilitating listerial expression of antigenic sequences and methods of preparation and use thereof
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
ES2822584T3 (es) 2013-05-03 2021-05-04 Univ California Inducción de dinucleótidos cíclicos del interferón tipo I
JP6453855B2 (ja) 2013-05-18 2019-01-16 アドゥロ バイオテック，インク． 「インターフェロン遺伝子の刺激因子」依存性シグナル伝達を活性化するための組成物及び方法
US9549944B2 (en) 2013-05-18 2017-01-24 Aduro Biotech, Inc. Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
EP3052106A4 (en) 2013-09-30 2017-07-19 ModernaTX, Inc. Polynucleotides encoding immune modulating polypeptides
EP3052521A1 (en) 2013-10-03 2016-08-10 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
SG10202011841WA (en) * 2014-04-24 2021-01-28 Advaxis Inc Recombinant listeria vaccine strains and methods of producing the same
US10925945B2 (en) 2014-10-13 2021-02-23 Providence Health & Services-Oregon Bacterial vaccines deficient in the 2-C-methyl-D-erythritol-4-phosphate pathway and methods of preparation and use thereof
MX2017004897A (es) * 2014-10-14 2018-02-09 Univ Pennsylvania Cepas vacunales recombinantes de listeria y metodos para usar las mismas en la inmunoterapia contra el cancer.
EP3215139B1 (en) 2014-11-03 2020-08-19 Cerus Corporation Compositions and methods for improved car-t cell therapies
JP6692826B2 (ja) 2015-03-10 2020-05-13 アドゥロ バイオテック，インク． 「インターフェロン遺伝子刺激因子」依存性シグナル伝達の活性化のための組成物及び方法
TW201704267A (zh) * 2015-04-13 2017-02-01 奧都羅生技公司 用於治療癌症的免疫性融合蛋白
CA2982533A1 (en) 2015-04-13 2016-10-20 Aduro Biotech, Inc. Epidermal growth factor receptor variant iii-mesothelin fusions and methods of using the same
US10455265B2 (en) * 2015-04-27 2019-10-22 Ericsson Ab Program and device class entitlements in a media platform
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TW201809274A (zh) * 2016-08-01 2018-03-16 美商艾杜諾生物科技公司 蛋白質表現強化子序列及其用途
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WO2021014398A1 (en) * 2019-07-23 2021-01-28 University Of Rijeka Faculty Of Medicine Integrated human cytomegalovirus / glioblastoma vaccine

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Also Published As

Publication number Publication date
US20180021420A1 (en) 2018-01-25
HRP20181343T1 (hr) 2018-10-19
PT2640842T (pt) 2018-10-12
HUE039747T2 (hu) 2019-02-28
JP2014504851A (ja) 2014-02-27
US9775891B2 (en) 2017-10-03
US20160074491A1 (en) 2016-03-17
CY1120622T1 (el) 2019-12-11
CA2818353A1 (en) 2012-05-24
JP5998370B2 (ja) 2016-09-28
WO2012068360A1 (en) 2012-05-24
US9200057B2 (en) 2015-12-01
SI2640842T1 (sl) 2018-09-28
LT2640842T (lt) 2018-09-10
ES2684684T3 (es) 2018-10-04
US20140037662A1 (en) 2014-02-06
EP2640842A4 (en) 2014-04-09
CN103415620B (zh) 2016-10-12
DK2640842T3 (en) 2018-08-13
RS57630B1 (sr) 2018-11-30
CN103415620A (zh) 2013-11-27
EP2640842B1 (en) 2018-05-30
EP2640842A1 (en) 2013-09-25

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