CA2818249C - Pharmaceutical compositions comprising radezolid, hydroxypropylmethyl cellulose polymer, and a physical mixture - Google Patents
Pharmaceutical compositions comprising radezolid, hydroxypropylmethyl cellulose polymer, and a physical mixture Download PDFInfo
- Publication number
- CA2818249C CA2818249C CA2818249A CA2818249A CA2818249C CA 2818249 C CA2818249 C CA 2818249C CA 2818249 A CA2818249 A CA 2818249A CA 2818249 A CA2818249 A CA 2818249A CA 2818249 C CA2818249 C CA 2818249C
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- patient
- composition according
- microbial infection
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41680710P | 2010-11-24 | 2010-11-24 | |
| US61/416,807 | 2010-11-24 | ||
| PCT/US2011/061643 WO2012071324A2 (en) | 2010-11-24 | 2011-11-21 | Pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2818249A1 CA2818249A1 (en) | 2012-05-31 |
| CA2818249C true CA2818249C (en) | 2021-04-13 |
Family
ID=46146374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2818249A Active CA2818249C (en) | 2010-11-24 | 2011-11-21 | Pharmaceutical compositions comprising radezolid, hydroxypropylmethyl cellulose polymer, and a physical mixture |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20140088164A1 (https=) |
| EP (1) | EP2642996B1 (https=) |
| JP (2) | JP6370550B2 (https=) |
| KR (1) | KR101944124B1 (https=) |
| CN (1) | CN103391778B (https=) |
| AU (1) | AU2011332031B2 (https=) |
| BR (1) | BR112013012833A8 (https=) |
| CA (1) | CA2818249C (https=) |
| EA (1) | EA027791B1 (https=) |
| ES (1) | ES2836809T3 (https=) |
| HU (1) | HUE052801T2 (https=) |
| IL (1) | IL226378A0 (https=) |
| MX (1) | MX350565B (https=) |
| MY (2) | MY182136A (https=) |
| NZ (1) | NZ610638A (https=) |
| PH (1) | PH12013501069A1 (https=) |
| PT (1) | PT2642996T (https=) |
| SG (2) | SG10201509530YA (https=) |
| UA (1) | UA113722C2 (https=) |
| WO (1) | WO2012071324A2 (https=) |
| ZA (1) | ZA201303732B (https=) |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5688792A (en) | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| US5895663A (en) | 1997-07-31 | 1999-04-20 | L. Perrigo Company | Pseudoephedrine hydrochloride extended-release tablets |
| US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
| US20010053791A1 (en) * | 2000-03-16 | 2001-12-20 | Babcock Walter C. | Glycogen phosphorylase inhibitor |
| ES2312422T3 (es) | 2000-03-22 | 2009-03-01 | PHARMACIA & UPJOHN COMPANY LLC | Formulacion de comprimido de oxazolidinona. |
| PE20011088A1 (es) | 2000-03-22 | 2001-10-04 | Upjohn Co | Tratamiento de infecciones del tracto urinario con oxazolidinonas antibacterianas |
| BR0111280A (pt) | 2000-06-05 | 2003-06-10 | Dong A Pharm Co Ltd | Novos derivados de oxazolidinona e um processo para a preparação dos mesmos |
| BR0112393A (pt) * | 2000-06-21 | 2003-07-08 | Internat Health Man Associates | Composições e processos para aperfeiçoamento de absorção oral de agentes antimicrobiais |
| CA2431319A1 (en) | 2000-12-11 | 2002-06-20 | Hiroto Bando | Pharmaceutical composition having an improved water solubility |
| JP2002241268A (ja) * | 2000-12-11 | 2002-08-28 | Takeda Chem Ind Ltd | 水溶解性が改善された医薬組成物 |
| JP5043428B2 (ja) | 2003-06-03 | 2012-10-10 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | ビアリール複素環式化合物ならびにその製造および使用方法 |
| AR046782A1 (es) | 2003-12-17 | 2005-12-21 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos. |
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| TW200534879A (en) * | 2004-03-25 | 2005-11-01 | Bristol Myers Squibb Co | Coated tablet formulation and method |
| EP1877041A2 (en) * | 2005-04-29 | 2008-01-16 | Cubist Pharmaceuticals, Inc. | Therapeutic compositions |
| CN101272769B (zh) | 2005-07-28 | 2013-04-24 | Isp投资有限公司 | 生物利用度提高的苯醌类化合物 |
| US20070026072A1 (en) * | 2005-07-28 | 2007-02-01 | Stephen Olsen | Benzoquinones of enhanced bioavailability |
| US20070104785A1 (en) * | 2005-07-29 | 2007-05-10 | Navale Suryakant V | Tablets of linezolid form iii and processes for their preparation |
| JP5773560B2 (ja) | 2006-02-09 | 2015-09-02 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | Ｃｅｔｐ阻害剤のポリマー製剤 |
| PE20080422A1 (es) * | 2006-08-10 | 2008-04-28 | Cipla Ltd | Composicion solida antirretroviral de administracion oral |
| SG10201406571YA (en) * | 2009-10-13 | 2014-11-27 | Melinta Therapeutics Inc | Pharmaceutical compositions |
| JP5792807B2 (ja) * | 2010-06-14 | 2015-10-14 | ダウ グローバル テクノロジーズ エルエルシー | アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート |
| EP2635307B1 (en) | 2010-11-01 | 2020-07-29 | Melinta Subsidiary Corp. | Pharmaceutical compositions |
-
2011
- 2011-11-21 AU AU2011332031A patent/AU2011332031B2/en not_active Ceased
- 2011-11-21 ES ES11843190T patent/ES2836809T3/es active Active
- 2011-11-21 UA UAA201307892A patent/UA113722C2/uk unknown
- 2011-11-21 CN CN201180065667.4A patent/CN103391778B/zh not_active Expired - Fee Related
- 2011-11-21 SG SG10201509530YA patent/SG10201509530YA/en unknown
- 2011-11-21 MY MYPI2017000871A patent/MY182136A/en unknown
- 2011-11-21 EP EP11843190.7A patent/EP2642996B1/en active Active
- 2011-11-21 NZ NZ610638A patent/NZ610638A/en not_active IP Right Cessation
- 2011-11-21 PT PT118431907T patent/PT2642996T/pt unknown
- 2011-11-21 KR KR1020137013466A patent/KR101944124B1/ko not_active Expired - Fee Related
- 2011-11-21 JP JP2013540991A patent/JP6370550B2/ja active Active
- 2011-11-21 EA EA201390764A patent/EA027791B1/ru not_active IP Right Cessation
- 2011-11-21 MY MYPI2013001885A patent/MY171941A/en unknown
- 2011-11-21 PH PH1/2013/501069A patent/PH12013501069A1/en unknown
- 2011-11-21 WO PCT/US2011/061643 patent/WO2012071324A2/en not_active Ceased
- 2011-11-21 CA CA2818249A patent/CA2818249C/en active Active
- 2011-11-21 HU HUE11843190A patent/HUE052801T2/hu unknown
- 2011-11-21 MX MX2013005813A patent/MX350565B/es active IP Right Grant
- 2011-11-21 SG SG2013038971A patent/SG190354A1/en unknown
- 2011-11-21 US US13/988,908 patent/US20140088164A1/en not_active Abandoned
- 2011-11-21 BR BR112013012833A patent/BR112013012833A8/pt not_active Application Discontinuation
-
2013
- 2013-05-16 IL IL226378A patent/IL226378A0/en unknown
- 2013-05-22 ZA ZA2013/03732A patent/ZA201303732B/en unknown
-
2016
- 2016-09-09 US US15/260,424 patent/US10300046B2/en active Active
- 2016-12-15 JP JP2016243035A patent/JP2017081950A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
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| AU2016234893A1 (en) | Pharmaceutical Compositions | |
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| US20200237744A1 (en) | Antimicrobial Compositions with Effervescent Agents | |
| HK1230972A1 (en) | Pharmaceutical compositions comprising radezolid | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20161118 |