PE20080422A1 - Composicion solida antirretroviral de administracion oral - Google Patents

Composicion solida antirretroviral de administracion oral

Info

Publication number
PE20080422A1
PE20080422A1 PE2007001072A PE2007001072A PE20080422A1 PE 20080422 A1 PE20080422 A1 PE 20080422A1 PE 2007001072 A PE2007001072 A PE 2007001072A PE 2007001072 A PE2007001072 A PE 2007001072A PE 20080422 A1 PE20080422 A1 PE 20080422A1
Authority
PE
Peru
Prior art keywords
composition
polymer
refers
vinyl acetate
solid
Prior art date
Application number
PE2007001072A
Other languages
English (en)
Inventor
Amar Lulla
Geena Malhotra
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of PE20080422A1 publication Critical patent/PE20080422A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA SOLIDA QUE COMPRENDE: A) DOS INHIBIDORES DE PROTEASA DEL VIRUS DE INMUNODEFICIENCIA HUMANA (VIH) TAL COMO LOPINAVIR, RITONAVIR, ENTRE OTROS; B) UN POLIMERO INSOLUBLE EN AGUA TAL COMO COPOLIMEROS ACRILICOS, POLI(ACETATO DE VINILO), ETILCELULOSA, ENTRE OTROS, EN DONDE LA RELACION DE FARMACO A POLIMERO EN LA COMPOSICION ES DE 1:1 A 1:6; C) UN POLIMERO SOLUBLE EN AGUA TAL COMO POLIVINILPIRROLIDONA, ACETATO DE VINILO, OXIDO DE POLIETILENO, ENTRE OTROS; D) UN PLASTIFICANTE TAL COMO MONOLAURATO DE SORBITAN, CITRATO DE TRIETILO, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE HASTA 10%; E) AGENTES DE RELLENO TAL COMO SACARIDOS, CELULOSA EN POLVO, AZUCAR PURIFICADA, ENTRE OTROS; F) AGENTES DE SABOR TAL COMO ACIDO CITRICO, ACIDO TARTARICO, ACIDO LACTICO, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE SIDA
PE2007001072A 2006-08-10 2007-08-10 Composicion solida antirretroviral de administracion oral PE20080422A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1269MU2006 2006-08-10
IN1227MU2007 2007-06-27

Publications (1)

Publication Number Publication Date
PE20080422A1 true PE20080422A1 (es) 2008-04-28

Family

ID=38667164

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001072A PE20080422A1 (es) 2006-08-10 2007-08-10 Composicion solida antirretroviral de administracion oral

Country Status (9)

Country Link
US (1) US20100173921A1 (es)
AU (1) AU2007283196A1 (es)
BR (1) BRPI0714265A2 (es)
CA (1) CA2660374A1 (es)
CL (1) CL2007002331A1 (es)
PE (1) PE20080422A1 (es)
TW (1) TW200815033A (es)
UY (1) UY30535A1 (es)
WO (1) WO2008017867A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2487166T (lt) 2007-02-23 2016-11-10 Gilead Sciences, Inc. Terapinių agentų farmakokinetinių savybių moduliatoriai
SG190618A1 (en) * 2008-05-02 2013-06-28 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
WO2009153654A1 (en) * 2008-06-17 2009-12-23 Aurobindo Pharma Limited Solid dosage forms of antiretrovirals
KR20110081176A (ko) * 2008-10-03 2011-07-13 하. 룬드벡 아크티에셀스카브 경구용 제형물
EA020783B1 (ru) * 2008-10-07 2015-01-30 Астразенека Юк Лимитед Фармацевтическая композиция, содержащая 4-[3-(4-циклопропанкарбонилпиперазин-1-карбонил)-4-фторбензил]-2н-фталазин-1-он и коповидон
GB201006038D0 (en) 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions
CN102985074B (zh) * 2010-05-10 2015-09-02 赢创罗姆有限公司 包含一种或多种抗逆转录病毒活性成分的药物剂型
ES2836809T3 (es) * 2010-11-24 2021-06-28 Melinta Subsidiary Corp Composiciones farmacéuticas
GB201118182D0 (en) * 2011-10-21 2011-12-07 Jagotec Ag Improvements in or relating to organic compounds
US9370578B2 (en) * 2012-03-07 2016-06-21 Ratiopharm Gmbh Dosage form comprising lopinavir and ritonavir
US20150086628A1 (en) * 2012-05-03 2015-03-26 Cipla Limited Antiretroviral composition
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
WO2014080365A1 (en) * 2012-11-23 2014-05-30 Ranbaxy Laboratories Limited Method of reducing an unpleasant odor of a pharmaceutical composition
RU2505286C1 (ru) * 2012-12-29 2014-01-27 Открытое Акционерное Общество "Фармасинтез" Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения
CN103550993B (zh) * 2013-10-30 2015-07-08 王维玲 一种大气污染洁净剂及制备方法、洁净剂的应用及应用方法
MA41411B1 (fr) * 2015-01-27 2023-07-31 Janssen Pharmaceutica Nv Compositions dispersibles
EP3398587B1 (en) * 2015-12-28 2023-08-02 SSP Co., Ltd., Japan Compacted pharmaceutical preparation
GB2625584A (en) * 2022-12-21 2024-06-26 Rb Health Us Llc Novel composition

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552558A (en) * 1989-05-23 1996-09-03 Abbott Laboratories Retroviral protease inhibiting compounds
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
JP4101661B2 (ja) * 2001-05-03 2008-06-18 エフ．ホフマン−ラ ロシュ アーゲー 非晶質メシル酸ネルフィナビルの製薬剤形
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US20050048112A1 (en) * 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
WO2007013047A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Water-dispersible anti-retroviral pharmaceutical compositions
ES2427724T3 (es) * 2006-02-03 2013-10-31 Evonik Röhm Gmbh Composiciones farmacéuticas, que contienen mezclas de polímeros y de sustancias activas difícilmente solubles en agua

Also Published As

Publication number Publication date
CA2660374A1 (en) 2008-02-14
WO2008017867A2 (en) 2008-02-14
WO2008017867A3 (en) 2009-04-16
AU2007283196A1 (en) 2008-02-14
UY30535A1 (es) 2008-03-31
TW200815033A (en) 2008-04-01
US20100173921A1 (en) 2010-07-08
CL2007002331A1 (es) 2008-04-18
BRPI0714265A2 (pt) 2013-04-16

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