CA2811990C - Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators - Google Patents

Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators Download PDF

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CA2811990C
CA2811990C CA2811990A CA2811990A CA2811990C CA 2811990 C CA2811990 C CA 2811990C CA 2811990 A CA2811990 A CA 2811990A CA 2811990 A CA2811990 A CA 2811990A CA 2811990 C CA2811990 C CA 2811990C
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aryl
alkyl
heterocyclyl
compound
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CA2811990A1 (en
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Dean Y. Maeda
John A. Zebala
Aaron D. Schuler
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Syntrix Biosystems Inc
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Syntrix Biosystems Inc
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CA2811990A 2010-08-23 2011-08-22 Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators Active CA2811990C (en)

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US37622410P 2010-08-23 2010-08-23
US61/376,224 2010-08-23
PCT/US2011/048668 WO2012027289A1 (en) 2010-08-23 2011-08-22 Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators

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CA2811990A1 CA2811990A1 (en) 2012-03-01
CA2811990C true CA2811990C (en) 2023-03-21

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EP (1) EP2608672B1 (enExample)
JP (3) JP6486002B2 (enExample)
AU (1) AU2011293612B2 (enExample)
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Families Citing this family (13)

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EP2942346B1 (en) 2009-02-17 2020-05-06 Syntrix Biosystems, Inc. Pyridinecarboxamides as cxcr2 modulators
AU2011293612B2 (en) * 2010-08-23 2015-11-26 Syntrix Biosystems Inc. Aminopyridine- and aminopyrimidinecarboxamides as CXCR2 modulators
CN110420316A (zh) 2013-06-18 2019-11-08 纽约大学 参与金黄色葡萄球菌杀白细胞素的细胞毒性的细胞因素：新型治疗靶点
US8969365B2 (en) * 2013-08-02 2015-03-03 Syntrix Biosystems, Inc. Thiopyrimidinecarboxamides as CXCR1/2 modulators
US10561676B2 (en) 2013-08-02 2020-02-18 Syntrix Biosystems Inc. Method for treating cancer using dual antagonists of CXCR1 and CXCR2
EP3027627B1 (en) * 2013-08-02 2018-01-31 Syntrix Biosystems Inc. 2-[5-[n-(4-fluorophenyl)carbamoyl]pyrimidin-2-ylsulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
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