CA2793878C - Residual compensation for a biosensor - Google Patents
Residual compensation for a biosensor Download PDFInfo
- Publication number
- CA2793878C CA2793878C CA2793878A CA2793878A CA2793878C CA 2793878 C CA2793878 C CA 2793878C CA 2793878 A CA2793878 A CA 2793878A CA 2793878 A CA2793878 A CA 2793878A CA 2793878 C CA2793878 C CA 2793878C
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- Expired - Fee Related
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31617410P | 2010-03-22 | 2010-03-22 | |
| US61/316,174 | 2010-03-22 | ||
| PCT/US2011/029318 WO2011119533A1 (en) | 2010-03-22 | 2011-03-22 | Residual compensation for a biosensor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2793878A1 CA2793878A1 (en) | 2011-09-29 |
| CA2793878C true CA2793878C (en) | 2018-09-11 |
Family
ID=44065188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2793878A Expired - Fee Related CA2793878C (en) | 2010-03-22 | 2011-03-22 | Residual compensation for a biosensor |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10591436B2 (enExample) |
| EP (1) | EP2550530A1 (enExample) |
| JP (1) | JP6096655B2 (enExample) |
| KR (1) | KR101929057B1 (enExample) |
| CN (1) | CN103003692B (enExample) |
| BR (1) | BR112012023984A2 (enExample) |
| CA (1) | CA2793878C (enExample) |
| MX (2) | MX368104B (enExample) |
| RU (1) | RU2568884C2 (enExample) |
| WO (1) | WO2011119533A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012023984A2 (pt) | 2010-03-22 | 2016-08-02 | Bayer Healthcare Llc | compensação residual para um biossensor |
| JP5856155B2 (ja) * | 2010-06-07 | 2016-02-09 | バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC | バイオセンサのための充填不足管理システム |
| ES2812806T3 (es) * | 2013-03-14 | 2021-03-18 | Ascensia Diabetes Care Holdings Ag | Calibración normalizada de determinaciones de la concentración de analito |
| EP2972397B1 (en) | 2013-03-14 | 2021-10-13 | Ascensia Diabetes Care Holdings AG | System error compensation of analyte concentration determinations |
| ES2715407T3 (es) * | 2013-03-14 | 2019-06-04 | Ascensia Diabetes Care Holdings Ag | Aproximación progresiva de la concentración de un analito de muestra |
| EP2781919A1 (en) * | 2013-03-19 | 2014-09-24 | Roche Diagniostics GmbH | Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid |
| CN107636452B (zh) | 2015-05-15 | 2021-06-08 | 安晟信医疗科技控股公司 | 改进的生物传感器系统分析物测量 |
| CN109690304A (zh) | 2016-07-12 | 2019-04-26 | 安晟信医疗科技控股公司 | 通过使用来自两个电极的交替输出信号进行电化学分析的方法 |
| HUE052845T2 (hu) * | 2016-09-07 | 2021-05-28 | Hoffmann La Roche | Eljárások enzimalapú elektrokémiai érzékelõk tesztelésére |
| CN110249219B (zh) | 2016-12-05 | 2022-08-23 | 安晟信医疗科技控股公司 | 风险因素监测 |
| CN109682968B (zh) * | 2018-11-08 | 2022-03-11 | 上海艾瑞德生物科技有限公司 | 一种荧光免疫试条定量检测测试信号温度矫正方法 |
| EP4064988A4 (en) | 2019-11-27 | 2023-11-29 | Senseonics, Incorporated | METHODS AND SYSTEMS FOR REDUCE THE DIFFERENCE BETWEEN CALCULATED AND MEASURED ANALYTE RATES |
| US12478297B2 (en) | 2019-11-27 | 2025-11-25 | Senseonics, Incorporated | Methods and systems for reducing difference between calculated and measured analyte levels |
| CN111812175B (zh) * | 2020-06-30 | 2022-06-14 | 江苏鱼跃医疗设备股份有限公司 | 一种降低红细胞比容干扰的血液检测方法及生物传感器 |
| CN113607801B (zh) * | 2021-08-09 | 2023-09-29 | 湖南国天电子科技有限公司 | 一种多级可控激发电压控制模块延长传感器寿命的方法 |
Family Cites Families (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431004A (en) | 1981-10-27 | 1984-02-14 | Bessman Samuel P | Implantable glucose sensor |
| US4750496A (en) | 1987-01-28 | 1988-06-14 | Xienta, Inc. | Method and apparatus for measuring blood glucose concentration |
| SE466157B (sv) * | 1989-04-25 | 1992-01-07 | Migrata Uk Ltd | Saett att bestaemma glukoshalten hos helblod samt engaangskuvett foer detta |
| US5243516A (en) | 1989-12-15 | 1993-09-07 | Boehringer Mannheim Corporation | Biosensing instrument and method |
| US5508171A (en) | 1989-12-15 | 1996-04-16 | Boehringer Mannheim Corporation | Assay method with enzyme electrode system |
| FR2701117B1 (fr) | 1993-02-04 | 1995-03-10 | Asulab Sa | Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose. |
| US5366609A (en) | 1993-06-08 | 1994-11-22 | Boehringer Mannheim Corporation | Biosensing meter with pluggable memory key |
| US5352351A (en) | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
| RU2135993C1 (ru) * | 1994-07-12 | 1999-08-27 | Научно-исследовательский институт радиоэлектроники и лазерной техники МГТУ им.Н.Э.Баумана | Устройство для определения концентрации водно-спиртового раствора |
| IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
| US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
| US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| US5723284A (en) | 1996-04-01 | 1998-03-03 | Bayer Corporation | Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood |
| DK0958495T3 (da) | 1997-02-06 | 2003-03-10 | Therasense Inc | In vitro analysand sensor med lille volumen |
| US6391558B1 (en) | 1997-03-18 | 2002-05-21 | Andcare, Inc. | Electrochemical detection of nucleic acid sequences |
| US5798031A (en) | 1997-05-12 | 1998-08-25 | Bayer Corporation | Electrochemical biosensor |
| US6391645B1 (en) | 1997-05-12 | 2002-05-21 | Bayer Corporation | Method and apparatus for correcting ambient temperature effect in biosensors |
| JP2002505008A (ja) | 1997-06-16 | 2002-02-12 | エラン コーポレーション ピーエルシー | 分析物のin vivo測定のためのセンサーをキャリブレートし、試験する方法と、このような方法に用いるためのデバイス |
| HU222809B1 (hu) | 1997-10-03 | 2003-10-28 | 77 Elektronika Műszeripari Kft. | Eljárás és készülék kémiai összetevőnek anyagmintából, különösen vér glükóztartalmának vérmintából történő meghatározásához |
| DE69840916D1 (de) | 1997-12-22 | 2009-07-30 | Roche Diagnostics Operations | Messgerät |
| ATE258028T1 (de) | 1998-05-13 | 2004-02-15 | Cygnus Therapeutic Systems | Signalverarbeitung zur messung von physiologischen analyten |
| US6576117B1 (en) | 1998-05-20 | 2003-06-10 | Arkray | Method and apparatus for electrochemical measurement using statistical technique |
| US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
| CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
| CA2385842C (en) | 1999-09-20 | 2008-12-09 | Roche Diagnostics Corporation | Small volume biosensor for continuous analyte monitoring |
| US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
| JP4050434B2 (ja) | 1999-11-29 | 2008-02-20 | 松下電器産業株式会社 | サンプルの弁別方法 |
| RU2194987C2 (ru) * | 2000-05-26 | 2002-12-20 | Научно-исследовательский институт кардиологии Томского научного центра СО РАМН | Способ количественного определения катехоламинов в моче |
| JP3972063B2 (ja) | 2001-01-17 | 2007-09-05 | アークレイ株式会社 | センサを用いる定量分析方法および定量分析装置 |
| US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
| US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
| AU784254B2 (en) | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
| US6797150B2 (en) | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| US7491310B2 (en) | 2001-10-12 | 2009-02-17 | Arkray, Inc. | Concentration measuring method and concentration measuring apparatus |
| US6872298B2 (en) * | 2001-11-20 | 2005-03-29 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| CA2419213C (en) | 2002-03-07 | 2011-06-21 | Bayer Healthcare Llc | Improved electrical sensor |
| US6964871B2 (en) | 2002-04-25 | 2005-11-15 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US6946299B2 (en) | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| AU2003234944A1 (en) | 2002-08-27 | 2004-03-18 | Bayer Healthcare, Llc | Methods of Determining Glucose Concentration in Whole Blood Samples |
| EP1422523B1 (en) | 2002-11-21 | 2007-05-23 | Lifescan, Inc. | Determination of sample volume adequacy in biosensors |
| US7132041B2 (en) | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| RU2241985C1 (ru) * | 2003-03-27 | 2004-12-10 | Томский политехнический университет | Способ количественного определения азитромицина дигидрата методом инверсионной вольтамперометрии |
| EP1467206A1 (en) * | 2003-04-08 | 2004-10-13 | Roche Diagnostics GmbH | Biosensor system |
| JP4222896B2 (ja) * | 2003-07-25 | 2009-02-12 | テルモ株式会社 | 成分測定装置 |
| US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| US7488601B2 (en) | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
| ES2709991T3 (es) | 2003-08-21 | 2019-04-22 | Agamatrix Inc | Método y aparato para el análisis de propiedades electroquímicas |
| JP4449431B2 (ja) | 2003-11-19 | 2010-04-14 | パナソニック株式会社 | 基質濃度の測定方法 |
| EP1714148B1 (en) | 2004-02-06 | 2011-11-02 | Bayer HealthCare LLC | Electrochemical biosensor |
| EP1568311A1 (en) * | 2004-02-27 | 2005-08-31 | Hitachi, Ltd. | Blood sugar level measuring apparatus |
| KR101196278B1 (ko) | 2004-03-08 | 2012-11-06 | 쉘 인터내셔날 리써취 마트샤피지 비.브이. | 반응기용 가스 분배기 |
| CN1938590B (zh) | 2004-04-19 | 2010-05-05 | 松下电器产业株式会社 | 血液成分的测定方法、该方法中使用的生物传感器和测定装置 |
| RU2006144458A (ru) | 2004-05-14 | 2008-06-20 | БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) | Способы осуществления корректировки по гематокриту в анализах глюкозы и устройства для этого |
| KR101365933B1 (ko) | 2004-10-12 | 2014-02-24 | 바이엘 헬스케어 엘엘씨 | 샘플 내 분석물의 농도를 측정하기 위한 전기화학 시스템 |
| GB0501826D0 (en) | 2005-01-28 | 2005-03-09 | Melys Diagnostics Ltd | Apparatus for measurement of analyte concentration |
| BRPI0609633B1 (pt) | 2005-04-08 | 2016-01-26 | Bayer Healthcare Llc | espécies oxidáveis como uma referência interna em soluções de controle para biossensores |
| US7517439B2 (en) | 2005-04-15 | 2009-04-14 | Agamatrix, Inc. | Error detection in analyte measurements based on measurement of system resistance |
| ES2717135T3 (es) | 2005-07-20 | 2019-06-19 | Ascensia Diabetes Care Holdings Ag | Método para señalar al usuario para que añada una muestra adicional a una tira de prueba, método para medir la temperatura de una muestra y métodos para determinar la concentración de un analito basados en amperometría controlada |
| CN110376270A (zh) * | 2005-07-20 | 2019-10-25 | 安晟信医疗科技控股公司 | 测定样品温度的方法 |
| KR101477815B1 (ko) | 2005-09-30 | 2015-01-02 | 바이엘 헬스케어 엘엘씨 | 게이트형 전압 전류 측정법 |
| CA3044828A1 (en) | 2006-02-27 | 2007-09-07 | Ascensia Diabetes Care Holdings Ag | Temperature adjusted analyte determination for biosensor systems |
| US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
| BRPI0711433A2 (pt) | 2006-05-08 | 2011-11-16 | Bayer Healthcare Llc | sistema de detecção de saìda anormal para um biosensor |
| CN101490531B (zh) * | 2006-05-16 | 2012-12-05 | 爱科来株式会社 | 控制液的自动判别方法 |
| US7699973B2 (en) * | 2006-06-30 | 2010-04-20 | Abbott Diabetes Care Inc. | Rapid analyte measurement assay |
| US7822557B2 (en) | 2006-10-31 | 2010-10-26 | Abbott Diabetes Care Inc. | Analyte sensors and methods |
| US8658094B2 (en) | 2007-01-29 | 2014-02-25 | Nalco Company | High temperature and pressure oxidation-reduction potential measuring and monitoring device for hot water systems |
| US20080248581A1 (en) | 2007-04-06 | 2008-10-09 | Bayer Healthcare Llc | Method for performing correction of blood glucose assay bias using blood hemoglobin concentration |
| US8101062B2 (en) | 2007-07-26 | 2012-01-24 | Nipro Diagnostics, Inc. | System and methods for determination of analyte concentration using time resolved amperometry |
| JP5604298B2 (ja) | 2007-07-26 | 2014-10-08 | ニプロ ダイアグナスティックス,インコーポレーテッド | 時間分解電流測定法を用いて被分析物の濃度を測定する方法及びシステム |
| JP5812603B2 (ja) * | 2007-12-10 | 2015-11-17 | バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC | 勾配ベース補正 |
| RU2509304C2 (ru) | 2008-12-08 | 2014-03-10 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Биосенсорная система с корректировкой сигнала |
| WO2010077669A2 (en) | 2008-12-08 | 2010-07-08 | Teva Pharmaceutical Industries Ltd. | Palonosetron formulation |
| CA2776332C (en) | 2009-11-10 | 2018-05-01 | Bayer Healthcare Llc | Underfill recognition system for a biosensor |
| BR112012023984A2 (pt) * | 2010-03-22 | 2016-08-02 | Bayer Healthcare Llc | compensação residual para um biossensor |
| WO2011156152A1 (en) | 2010-06-07 | 2011-12-15 | Bayer Healthcare Llc | Slope-based compensation including secondary output signals |
| ES2757909T3 (es) * | 2011-09-21 | 2020-04-30 | Ascensia Diabetes Care Holdings Ag | Analisis de compensación que incluye señales segmentadas |
| ES2715407T3 (es) * | 2013-03-14 | 2019-06-04 | Ascensia Diabetes Care Holdings Ag | Aproximación progresiva de la concentración de un analito de muestra |
| EP2972397B1 (en) * | 2013-03-14 | 2021-10-13 | Ascensia Diabetes Care Holdings AG | System error compensation of analyte concentration determinations |
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2011
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- 2011-03-22 KR KR1020127027529A patent/KR101929057B1/ko active Active
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- 2011-03-22 US US13/053,722 patent/US10591436B2/en active Active
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| JP2013522647A (ja) | 2013-06-13 |
| WO2011119533A1 (en) | 2011-09-29 |
| CA2793878A1 (en) | 2011-09-29 |
| US20110231105A1 (en) | 2011-09-22 |
| MX2012010860A (es) | 2013-03-05 |
| BR112012023984A2 (pt) | 2016-08-02 |
| RU2012144625A (ru) | 2014-04-27 |
| HK1177260A1 (en) | 2013-08-16 |
| EP2550530A1 (en) | 2013-01-30 |
| KR20130016311A (ko) | 2013-02-14 |
| CN103003692A (zh) | 2013-03-27 |
| KR101929057B1 (ko) | 2018-12-13 |
| US11988626B2 (en) | 2024-05-21 |
| US20200173952A1 (en) | 2020-06-04 |
| CN103003692B (zh) | 2015-01-14 |
| US10591436B2 (en) | 2020-03-17 |
| MX368104B (es) | 2019-09-19 |
| RU2568884C2 (ru) | 2015-11-20 |
| JP6096655B2 (ja) | 2017-03-15 |
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