CA2789595C - Methods and compositions to improve mechanical resistance of teeth - Google Patents

Methods and compositions to improve mechanical resistance of teeth Download PDF

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Publication number
CA2789595C
CA2789595C CA2789595A CA2789595A CA2789595C CA 2789595 C CA2789595 C CA 2789595C CA 2789595 A CA2789595 A CA 2789595A CA 2789595 A CA2789595 A CA 2789595A CA 2789595 C CA2789595 C CA 2789595C
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CA
Canada
Prior art keywords
composition
phosphate
theobromine
combinations
calcium
Prior art date
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Active
Application number
CA2789595A
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English (en)
French (fr)
Other versions
CA2789595A1 (en
Inventor
Arman Sadeghpour
Tetsuo Nakamoto
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THEOCORP HOLDING CO LLC
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THEOCORP HOLDING CO LLC
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Filing date
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Publication of CA2789595A1 publication Critical patent/CA2789595A1/en
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Publication of CA2789595C publication Critical patent/CA2789595C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
CA2789595A 2010-02-12 2011-02-14 Methods and compositions to improve mechanical resistance of teeth Active CA2789595C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30377410P 2010-02-12 2010-02-12
US61/303,774 2010-02-12
PCT/US2011/024734 WO2011100671A2 (en) 2010-02-12 2011-02-14 Methods and compositions to improve mechanical resistance of teeth

Publications (2)

Publication Number Publication Date
CA2789595A1 CA2789595A1 (en) 2011-08-18
CA2789595C true CA2789595C (en) 2017-11-28

Family

ID=44368492

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2789595A Active CA2789595C (en) 2010-02-12 2011-02-14 Methods and compositions to improve mechanical resistance of teeth

Country Status (16)

Country Link
US (1) US9610235B2 (https=)
EP (1) EP2533786B1 (https=)
JP (1) JP6114036B2 (https=)
KR (1) KR20120123534A (https=)
CN (2) CN102821768A (https=)
AU (1) AU2011215617B2 (https=)
BR (1) BR112012019844A2 (https=)
CA (1) CA2789595C (https=)
ES (1) ES2617758T3 (https=)
IL (1) IL221403A0 (https=)
MX (1) MX2012009313A (https=)
NZ (1) NZ601989A (https=)
RU (1) RU2591084C2 (https=)
SG (2) SG10201500795WA (https=)
WO (1) WO2011100671A2 (https=)
ZA (1) ZA201206742B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2698824T3 (es) 2006-02-09 2019-02-06 Univ Melbourne Composición dentífrica con fluoruro
KR20120123534A (ko) 2010-02-12 2012-11-08 씨오코프 홀딩 컴퍼니, 엘엘씨 치아의 기계적 내성을 향상시키는 방법 및 조성물
CN104411315A (zh) 2012-06-20 2015-03-11 斯欧考普控股公司 含有可可碱的组合物和它们在治疗牙齿过敏症中的用途
BR112015022471A2 (pt) * 2013-03-15 2017-08-22 Theocorp Holding Co Llc Composições de teobromina úteis para aumentar o ganho de peso do feto e acentuar as propriedades ósseas
CN105530909A (zh) 2013-07-23 2016-04-27 墨尔本大学 用于牙齿矿化的组合物及方法
FR3011466A1 (fr) * 2013-10-09 2015-04-10 Roquette Freres Utilisation d'un polyol dans la remineralisation de l'email
ES2959412T3 (es) 2013-12-24 2024-02-26 Univ Melbourne Composiciones estañosas estabilizadas
KR102187824B1 (ko) * 2014-03-26 2020-12-07 주식회사 엘지생활건강 치면 부착용 겔 조성물 및 이를 포함하는 키트
JP2018502099A (ja) * 2014-12-24 2018-01-25 ザ ユニヴァーシティー オブ メルボルン 石灰化フルオリド組成物
JP7138352B2 (ja) 2017-03-14 2022-09-16 ザ ユニバーシティー オブ メルボルン 過敏症を治療するための複合体
JP7142943B2 (ja) 2017-03-14 2022-09-28 ザ ユニバーシティー オブ メルボルン 歯肉炎の処置
US12569417B2 (en) 2019-03-13 2026-03-10 The University Of Melbourne Compositions and methods for promoting mineralization
CN110917210B (zh) * 2019-12-27 2022-04-19 安徽医科大学 一种牙齿矿化漂白双功能糊剂、制备方法及应用
CN112094699B (zh) * 2020-09-27 2023-03-28 广西壮族自治区林业科学研究院 一种樟树纯露的提取方法
DE102021111354A1 (de) * 2021-05-03 2022-11-03 Dr. Kurt Wolff Gmbh & Co. Kg Mundpflegemittel
DE102021111387A1 (de) 2021-05-03 2022-11-03 Dr. Kurt Wolff Gmbh & Co. Kg Oralgel-Zusammensetzung und ihre Verwendung

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US5626838A (en) * 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5571502A (en) * 1995-08-08 1996-11-05 Enamelon Research Stable single-part compositions and the use thereof for remineralization of lesions in teeth
US6183711B1 (en) * 1995-12-27 2001-02-06 Tetsuo Nakamoto Apatite-forming-systems: methods and products
US20050054682A1 (en) * 1996-01-04 2005-03-10 Phillips Jeffrey O. Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same
JP3719874B2 (ja) * 1998-04-24 2005-11-24 サンスター株式会社 口腔用組成物
US6685920B2 (en) * 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
KR20030032484A (ko) * 2001-10-18 2003-04-26 롯데제과주식회사 발암 억제효능을 갖는 데오브로민
US20050152852A1 (en) * 2002-05-27 2005-07-14 Morinaga & Co., Ltd. Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria
WO2003099304A1 (en) * 2002-05-27 2003-12-04 Morinaga & Co., Ltd. Composition against periodontal bacteria and foods, drinks and mouth washers against periodontal bacteria containing the composition
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US20040034042A1 (en) * 2002-08-14 2004-02-19 Masao Tsuji Preservative composition
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DE102004041496A1 (de) * 2004-08-27 2006-03-02 Symrise Gmbh & Co. Kg Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack
JP4820320B2 (ja) * 2006-03-28 2011-11-24 花王株式会社 口腔用組成物
JP5633998B2 (ja) * 2006-09-27 2014-12-03 三栄源エフ・エフ・アイ株式会社 歯の再石灰化促進剤およびこれを含む口腔または経口用組成物
JP5354865B2 (ja) * 2007-03-30 2013-11-27 太陽化学株式会社 リン酸カルシウム溶解抑制剤
JP5553396B2 (ja) * 2007-04-10 2014-07-16 株式会社サンギ 再石灰化促進剤及び口腔用組成物
BRPI0817922A2 (pt) * 2007-10-01 2015-04-07 Colgate Palmolive Co Composição, e, processo de promover e/ou de manter saúde sistêmica
JP5196127B2 (ja) * 2007-12-19 2013-05-15 ライオン株式会社 口腔用組成物
JP5656368B2 (ja) 2009-05-29 2015-01-21 花王株式会社 歯磨剤
KR20120123534A (ko) 2010-02-12 2012-11-08 씨오코프 홀딩 컴퍼니, 엘엘씨 치아의 기계적 내성을 향상시키는 방법 및 조성물

Also Published As

Publication number Publication date
WO2011100671A2 (en) 2011-08-18
EP2533786B1 (en) 2016-12-28
EP2533786A2 (en) 2012-12-19
SG10201500795WA (en) 2015-04-29
EP2533786A4 (en) 2013-06-12
RU2591084C2 (ru) 2016-07-10
SG183277A1 (en) 2012-09-27
KR20120123534A (ko) 2012-11-08
JP6114036B2 (ja) 2017-04-12
CA2789595A1 (en) 2011-08-18
BR112012019844A2 (pt) 2017-12-05
NZ601989A (en) 2014-11-28
RU2012133316A (ru) 2014-03-20
AU2011215617B2 (en) 2016-01-28
US9610235B2 (en) 2017-04-04
ES2617758T3 (es) 2017-06-19
IL221403A0 (en) 2012-10-31
MX2012009313A (es) 2012-11-06
CN102821768A (zh) 2012-12-12
WO2011100671A3 (en) 2011-12-22
US20130129641A1 (en) 2013-05-23
CN106668064A (zh) 2017-05-17
AU2011215617A1 (en) 2012-09-13
ZA201206742B (en) 2013-05-29
JP2013519688A (ja) 2013-05-30

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