CA2785524C - Poudres nutritionnelles comprenant du beta-hydroxy-beta-methylbutyrate (hmb) seche par pulverisation - Google Patents
Poudres nutritionnelles comprenant du beta-hydroxy-beta-methylbutyrate (hmb) seche par pulverisation Download PDFInfo
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- CA2785524C CA2785524C CA2785524A CA2785524A CA2785524C CA 2785524 C CA2785524 C CA 2785524C CA 2785524 A CA2785524 A CA 2785524A CA 2785524 A CA2785524 A CA 2785524A CA 2785524 C CA2785524 C CA 2785524C
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- hmb
- nutritional
- protein
- beta
- spray dried
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- 239000000872 buffer Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 239000000828 canola oil Substances 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 1
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 229940099112 cornstarch Drugs 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 235000020247 cow milk Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000007580 dry-mixing Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- 229940009714 erythritol Drugs 0.000 description 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000019534 high fructose corn syrup Nutrition 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229940057917 medium chain triglycerides Drugs 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000003346 palm kernel oil Substances 0.000 description 1
- 235000019865 palm kernel oil Nutrition 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 235000020610 powder formula Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 230000004844 protein turnover Effects 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 208000001076 sarcopenia Diseases 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 238000012358 sourcing Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/40—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
- A23L3/46—Spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Abstract
L'invention concerne des poudres nutritionnelles comprenant du bêta-hydroxy-bêta-méthylbutyrate (HMB) et au moins une graisse et/ou un carbohydrate et/ou une protéine, le HMB étant séché par pulvérisation avec une partie de graisse et/ou de protéine et/ou de carbohydrate de la composition. L'invention concerne également un procédé pour préparer ces poudres, qui consiste à : 1) préparer une bouillie liquide comprenant HMB et la protéine et/ou le carbohydrate et/ou la graisse, et 2) sécher la bouillie par pulvérisation afin de produire une poudre nutritionnelle séchée par pulvérisation comprenant le HMB séché par pulvérisation. Les poudres nutritionnelles sont peu odorantes ou inodores.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29963210P | 2010-01-29 | 2010-01-29 | |
US61/299,632 | 2010-01-29 | ||
PCT/US2011/022935 WO2011094549A1 (fr) | 2010-01-29 | 2011-01-28 | Poudres nutritionelles comprenant du beta-hydroxy-beta-methylbutyrate seche par pulverisation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2785524A1 CA2785524A1 (fr) | 2011-08-04 |
CA2785524C true CA2785524C (fr) | 2015-10-13 |
Family
ID=43927918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2785524A Active CA2785524C (fr) | 2010-01-29 | 2011-01-28 | Poudres nutritionnelles comprenant du beta-hydroxy-beta-methylbutyrate (hmb) seche par pulverisation |
Country Status (19)
Country | Link |
---|---|
US (1) | US20110256299A1 (fr) |
EP (1) | EP2442673B1 (fr) |
JP (1) | JP5892947B2 (fr) |
CN (2) | CN106937742A (fr) |
AR (1) | AR089547A1 (fr) |
AU (1) | AU2011210683A1 (fr) |
BR (1) | BR112012018642A2 (fr) |
CA (1) | CA2785524C (fr) |
CO (1) | CO6592060A2 (fr) |
EC (1) | ECSP12012053A (fr) |
ES (1) | ES2426481T3 (fr) |
HK (1) | HK1165227A1 (fr) |
IL (1) | IL220588A0 (fr) |
MX (1) | MX2012008778A (fr) |
PE (1) | PE20121728A1 (fr) |
RU (1) | RU2012125879A (fr) |
SG (1) | SG182813A1 (fr) |
TW (1) | TWI508670B (fr) |
WO (1) | WO2011094549A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
WO2011094548A1 (fr) | 2010-01-29 | 2011-08-04 | Abbott Laboratories | Liquides nutritionnels comprenant un beta-hydroxy-beta-methylbutyrate emballes de maniere aseptique |
PE20121729A1 (es) | 2010-01-29 | 2013-01-16 | Abbott Lab | Emulsiones nutricionales que comprenden beta-hidroxi-beta-metilbutirato (hmb) de calcio |
TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣hmb及可溶性蛋白質之實質上透明營養液 |
JP2015515258A (ja) * | 2012-01-23 | 2015-05-28 | デリス・メディカル・リサーチ・ソシエテ・アノニム | トリグリセリド負荷試験食 |
US20140037813A1 (en) * | 2012-08-02 | 2014-02-06 | Mead Johnson Nutrition Company | Nutritional creamer composition |
MX2015013165A (es) * | 2013-03-15 | 2015-12-11 | Abbott Lab | Composiciones nutricionales para infantes prematuros que contienen acido beta-hidroxi-beta-metilbutirico para promover el crecimiento y la acrecion de masa corporal magra en infantes prematuros. |
MX2015013179A (es) * | 2013-03-15 | 2016-04-20 | Abbott Lab | Formula infantil con bajo contenido calorico que contiene acido beta-hidroxi-beta-metilbutirico. |
CN107660793A (zh) * | 2016-07-29 | 2018-02-06 | 费森尤斯卡比德国有限公司 | 营养粉及其生产方法 |
WO2018052758A1 (fr) * | 2016-09-13 | 2018-03-22 | Abbott Laboratories | Compositions nutritionnelles cétogènes |
JP6889879B2 (ja) * | 2017-03-31 | 2021-06-18 | 株式会社東洋新薬 | チュアブルタブレット |
JP7100882B2 (ja) | 2017-11-08 | 2022-07-14 | 株式会社東洋新薬 | 経口組成物 |
AU2019247478A1 (en) | 2018-04-06 | 2020-10-22 | Abbott Laboratories | Powdered nutritional compositions with HMB and protein system |
WO2020023557A1 (fr) * | 2018-07-23 | 2020-01-30 | Advance International Inc. | Produits nutritionnels thérapeutiques à base de protéines |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6291525B1 (en) * | 1999-09-08 | 2001-09-18 | Iowa State University Research Foundation, Inc. | Method for improving a human's perception of his emotional state |
WO2001028356A2 (fr) * | 1999-10-18 | 2001-04-26 | Muscletech Research And Development Inc. | Complement alimentaire destine a augmenter la masse maigre et la resistance de celle-ci |
EP1255454A2 (fr) * | 2000-02-01 | 2002-11-13 | Muscletech Research and Development Inc. | Complement alimentaire a base d'acide alpha-lipoique destine a la masse maigre et a la resistance musculaire |
US6521591B1 (en) * | 2000-02-10 | 2003-02-18 | N.V. Nutricia | Pharmaceutical composition for muscular anabolism |
US20040048925A1 (en) * | 2002-09-09 | 2004-03-11 | Wiley David B. | Composition and method for enhancing the bioavailability of calcium and magnesium in dietary supplements and food additives |
US7445807B2 (en) * | 2002-10-15 | 2008-11-04 | Western Holdings, Llc | Agglomerated granular protein-rich nutritional supplement |
US7332178B2 (en) * | 2003-04-25 | 2008-02-19 | Abbott Laboratories | Stable nutritional powder containing ascorbyl palmitate |
US20050215640A1 (en) * | 2004-03-26 | 2005-09-29 | Baxter Jeffrey H | HMB compositions and uses thereof |
NO323912B1 (no) * | 2005-12-01 | 2007-07-16 | Tine Sa | Sammensetning, fremgangsmåte til fremstilling derav, og anvendelse derav. |
JP5227182B2 (ja) * | 2005-12-19 | 2013-07-03 | アボット・ラボラトリーズ | 1型および2型サイトカイン産生における不均衡を調節するためのベータ−ヒドロキシ−ベータ−メチルブチラートの使用 |
JP2008208118A (ja) * | 2007-01-29 | 2008-09-11 | Wakunaga Pharmaceut Co Ltd | ツルニンジン属植物抽出物含有粉末組成物 |
CN101574146B (zh) * | 2008-05-07 | 2012-06-13 | 北京康比特体育科技股份有限公司 | 一种含有hmb的运动营养补剂 |
-
2011
- 2011-01-28 JP JP2012551325A patent/JP5892947B2/ja active Active
- 2011-01-28 CN CN201710196516.1A patent/CN106937742A/zh active Pending
- 2011-01-28 US US13/016,041 patent/US20110256299A1/en not_active Abandoned
- 2011-01-28 PE PE2012001076A patent/PE20121728A1/es not_active Application Discontinuation
- 2011-01-28 BR BRBR112012018642-6A patent/BR112012018642A2/pt not_active IP Right Cessation
- 2011-01-28 TW TW100103533A patent/TWI508670B/zh active
- 2011-01-28 MX MX2012008778A patent/MX2012008778A/es active IP Right Grant
- 2011-01-28 AR ARP110100293A patent/AR089547A1/es not_active Application Discontinuation
- 2011-01-28 RU RU2012125879/13A patent/RU2012125879A/ru not_active Application Discontinuation
- 2011-01-28 ES ES11705724T patent/ES2426481T3/es active Active
- 2011-01-28 CN CN2011800077008A patent/CN102711523A/zh active Pending
- 2011-01-28 EP EP11705724.0A patent/EP2442673B1/fr active Active
- 2011-01-28 WO PCT/US2011/022935 patent/WO2011094549A1/fr active Application Filing
- 2011-01-28 SG SG2012056636A patent/SG182813A1/en unknown
- 2011-01-28 AU AU2011210683A patent/AU2011210683A1/en not_active Abandoned
- 2011-01-28 CA CA2785524A patent/CA2785524C/fr active Active
-
2012
- 2012-06-14 HK HK12105851.3A patent/HK1165227A1/xx unknown
- 2012-06-21 IL IL220588A patent/IL220588A0/en unknown
- 2012-07-19 CO CO12122156A patent/CO6592060A2/es not_active Application Discontinuation
- 2012-07-20 EC ECSP12012053 patent/ECSP12012053A/es unknown
Also Published As
Publication number | Publication date |
---|---|
HK1165227A1 (en) | 2012-10-05 |
BR112012018642A2 (pt) | 2015-09-01 |
AU2011210683A1 (en) | 2012-07-05 |
JP2013517806A (ja) | 2013-05-20 |
IL220588A0 (en) | 2012-08-30 |
WO2011094549A1 (fr) | 2011-08-04 |
MX2012008778A (es) | 2012-09-07 |
CN102711523A (zh) | 2012-10-03 |
TW201200037A (en) | 2012-01-01 |
PE20121728A1 (es) | 2013-01-13 |
CO6592060A2 (es) | 2013-01-02 |
TWI508670B (zh) | 2015-11-21 |
ECSP12012053A (es) | 2012-08-31 |
JP5892947B2 (ja) | 2016-03-23 |
EP2442673A1 (fr) | 2012-04-25 |
RU2012125879A (ru) | 2014-03-10 |
ES2426481T3 (es) | 2013-10-23 |
US20110256299A1 (en) | 2011-10-20 |
EP2442673B1 (fr) | 2013-07-10 |
CA2785524A1 (fr) | 2011-08-04 |
CN106937742A (zh) | 2017-07-11 |
SG182813A1 (en) | 2012-09-27 |
AR089547A1 (es) | 2014-09-03 |
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Effective date: 20130730 |