CA2784214C - Combination of theobromine with a decongestant and its use for the treatment of cough - Google Patents

Combination of theobromine with a decongestant and its use for the treatment of cough Download PDF

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Publication number
CA2784214C
CA2784214C CA2784214A CA2784214A CA2784214C CA 2784214 C CA2784214 C CA 2784214C CA 2784214 A CA2784214 A CA 2784214A CA 2784214 A CA2784214 A CA 2784214A CA 2784214 C CA2784214 C CA 2784214C
Authority
CA
Canada
Prior art keywords
decongestant
day
pseudoephedrine
cough
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2784214A
Other languages
English (en)
French (fr)
Other versions
CA2784214A1 (en
Inventor
John Brew
Robin Mark Bannister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Infirst Healthcare Ltd
Original Assignee
Infirst Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infirst Healthcare Ltd filed Critical Infirst Healthcare Ltd
Publication of CA2784214A1 publication Critical patent/CA2784214A1/en
Application granted granted Critical
Publication of CA2784214C publication Critical patent/CA2784214C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2784214A 2009-12-14 2010-12-14 Combination of theobromine with a decongestant and its use for the treatment of cough Expired - Fee Related CA2784214C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0921805.8 2009-12-14
GBGB0921805.8A GB0921805D0 (en) 2009-12-14 2009-12-14 Drug composition and its use in therapy
PCT/GB2010/052085 WO2011073646A1 (en) 2009-12-14 2010-12-14 Combination of theobromine with a decongestant and its use for the treatment of cough

Publications (2)

Publication Number Publication Date
CA2784214A1 CA2784214A1 (en) 2011-06-23
CA2784214C true CA2784214C (en) 2018-01-09

Family

ID=41667045

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2784214A Expired - Fee Related CA2784214C (en) 2009-12-14 2010-12-14 Combination of theobromine with a decongestant and its use for the treatment of cough

Country Status (18)

Country Link
EP (1) EP2512464A1 (es)
JP (2) JP2013513651A (es)
CN (2) CN105816462A (es)
AU (1) AU2010332494B2 (es)
BR (1) BR112012014161A2 (es)
CA (1) CA2784214C (es)
CO (1) CO6541630A2 (es)
EC (1) ECSP12012132A (es)
GB (1) GB0921805D0 (es)
IL (1) IL220383A (es)
MX (1) MX343222B (es)
NZ (1) NZ600243A (es)
PE (1) PE20121537A1 (es)
RU (1) RU2564904C2 (es)
SG (2) SG10201408377QA (es)
UA (1) UA105944C2 (es)
WO (1) WO2011073646A1 (es)
ZA (1) ZA201204293B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007103A1 (en) * 1993-09-07 1995-03-16 The Procter & Gamble Company Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
HUP9700654A2 (hu) 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US6417206B1 (en) * 2001-01-26 2002-07-09 Medpointe Healthcare Inc. Antitussive/antihist aminic/decongestant compositions
JP2002308761A (ja) * 2001-04-09 2002-10-23 Taisho Pharmaceut Co Ltd 風邪用咳止め薬
JP2003128549A (ja) * 2001-08-15 2003-05-08 Rohto Pharmaceut Co Ltd 粘膜適用組成物
JP4377564B2 (ja) * 2002-05-02 2009-12-02 ロート製薬株式会社 内服用組成物
RU2311919C2 (ru) * 2002-12-30 2007-12-10 Каунсел Оф Сайнтифик Энд Индастриал Рисерч Разработка противокашлевой и смягчающей горло травяной композиции
US20040202677A1 (en) * 2003-04-10 2004-10-14 Hopkins Kevin J. Method of enhanced regional body fat reduction
US20060153926A1 (en) * 2005-01-10 2006-07-13 Bascom Charles C Compositions, products and methods for controlling weight in a mammal
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
KR20080009994A (ko) * 2006-07-25 2008-01-30 안국약품 주식회사 기침 치료용 조성물
CN100518775C (zh) * 2007-03-16 2009-07-29 邓丽菊 一种治疗咳喘的药物组合物及其制剂

Also Published As

Publication number Publication date
BR112012014161A2 (pt) 2016-05-17
IL220383A (en) 2017-01-31
NZ600243A (en) 2013-07-26
ZA201204293B (en) 2013-02-27
IL220383A0 (en) 2012-08-30
JP2013513651A (ja) 2013-04-22
CN102740843A (zh) 2012-10-17
MX343222B (es) 2016-10-28
RU2564904C2 (ru) 2015-10-10
RU2012129839A (ru) 2014-01-27
AU2010332494A1 (en) 2012-06-14
CO6541630A2 (es) 2012-10-16
GB0921805D0 (en) 2010-01-27
JP2016040279A (ja) 2016-03-24
EP2512464A1 (en) 2012-10-24
MX2012006625A (es) 2012-10-05
PE20121537A1 (es) 2012-12-21
SG181686A1 (en) 2012-07-30
CA2784214A1 (en) 2011-06-23
SG10201408377QA (en) 2015-02-27
UA105944C2 (uk) 2014-07-10
ECSP12012132A (es) 2012-09-28
WO2011073646A1 (en) 2011-06-23
CN105816462A (zh) 2016-08-03
AU2010332494B2 (en) 2015-01-15

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20151214

MKLA Lapsed

Effective date: 20191216