CA2781166C - Procede de mesure homogene et reactif de mesure - Google Patents

Procede de mesure homogene et reactif de mesure Download PDF

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Publication number
CA2781166C
CA2781166C CA2781166A CA2781166A CA2781166C CA 2781166 C CA2781166 C CA 2781166C CA 2781166 A CA2781166 A CA 2781166A CA 2781166 A CA2781166 A CA 2781166A CA 2781166 C CA2781166 C CA 2781166C
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Canada
Prior art keywords
reagent
constituent
sample
silicone
reagents
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Active
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CA2781166A
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English (en)
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CA2781166A1 (fr
Inventor
Hiroshi Takahashi
Yuki Takahashi
Chie Kaneko
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Sekisui Medical Co Ltd
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Sekisui Medical Co Ltd
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Publication of CA2781166A1 publication Critical patent/CA2781166A1/fr
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un procédé de mesure homogène utilisant des particules supports insolubles ; en particulier, un procédé de mesure d'agrégation utilisant des particules supports insolubles portant des anticorps, des antigènes ou similaires. Plus spécifiquement, l'invention concerne un procédé de mesure LTIA qui diminue les effets de matrice du spécimen d'analyse et diminue également les différences de la précision de mesure entre des dispositifs d'analyse automatisés ayant des spécifications diverses. L'invention concerne également un réactif de mesure destiné à être utilisé avec un dispositif d'analyse automatisé. La formulation dudit réactif de mesure avec l'ajout d'un antimousse à la silicone diminue les effets de matrice du spécimen d'analyse et aussi, sans modifier les capacités fondamentales du réactif de mesure, diminue la variabilité de la précision de mesure entre les dispositifs d'analyse automatisés ayant des spécifications diverses.
CA2781166A 2009-11-30 2010-11-30 Procede de mesure homogene et reactif de mesure Active CA2781166C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009-272437 2009-11-30
JP2009272437 2009-11-30
PCT/JP2010/071402 WO2011065573A1 (fr) 2009-11-30 2010-11-30 Procédé de mesure homogène et réactif de mesure

Publications (2)

Publication Number Publication Date
CA2781166A1 CA2781166A1 (fr) 2011-06-03
CA2781166C true CA2781166C (fr) 2018-07-03

Family

ID=44066677

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2781166A Active CA2781166C (fr) 2009-11-30 2010-11-30 Procede de mesure homogene et reactif de mesure

Country Status (7)

Country Link
US (1) US20120258552A1 (fr)
EP (1) EP2508885B1 (fr)
JP (1) JP5806939B2 (fr)
KR (1) KR101826367B1 (fr)
CN (2) CN107632147A (fr)
CA (1) CA2781166C (fr)
WO (1) WO2011065573A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103038641B (zh) * 2010-03-31 2017-05-10 积水医疗株式会社 减少来自测量系统外部的成分的干扰的方法
JP2013079888A (ja) * 2011-10-05 2013-05-02 Hitachi High-Technologies Corp 自動分析装置
JP6242068B2 (ja) * 2013-04-10 2017-12-06 積水メディカル株式会社 ラテックス免疫凝集測定試薬
US10222375B2 (en) 2013-07-17 2019-03-05 Gold Standard Diagnostics Process and machine for automated agglutination assays with image automated evaluation
WO2016010584A1 (fr) * 2014-07-17 2016-01-21 Gold Standard Diagnostics, Inc. Procédé et machine pour essais d'agglutination automatisés
CN108700580B (zh) * 2016-02-12 2021-12-14 Jsr株式会社 添加剂、表面处理剂、表面改性乳胶粒子、表面改性乳胶粒子的制造方法、乳胶凝聚反应用试剂、试剂盒、以及靶物质的检测方法
JP6595743B1 (ja) * 2017-12-27 2019-10-23 積水メディカル株式会社 血清または血漿分離用組成物、血液採取容器、及び血清または血漿の分離方法
TWI842764B (zh) 2018-11-09 2024-05-21 日商積水醫療股份有限公司 抑制以自動分析裝置進行的免疫測定中之異常檢測的方法、檢測方法、免疫測定試劑、及免疫測定試劑套組
CN112578130A (zh) * 2019-09-30 2021-03-30 积水医疗科技(苏州)有限公司 凝血酶溶液、试剂盒、凝血酶的稳定化方法、检测试剂以及凝血酶时间的测定方法

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JPS6414628A (en) 1987-07-09 1989-01-18 Hitachi Ltd Input device by pointing device
US4970359A (en) * 1987-09-30 1990-11-13 Ki Tae Oh Automatic cooking control systems for a microwave oven
US4988618A (en) * 1987-11-16 1991-01-29 Gene-Trak Systems Magnetic separation device and methods for use in heterogeneous assays
US5830479A (en) * 1994-02-09 1998-11-03 Willmar Poultry Company, Inc. Active immunization using a siderophore receptor protein
DE69527877T2 (de) * 1994-04-29 2003-04-30 Seradyn, Inc. Mikropartikel-Immunoassayreagentien, empfindliche und spezifische Immunoassayreagentien und Immunoassaymethode
JP3071678B2 (ja) 1995-08-31 2000-07-31 三洋化成工業株式会社 免疫反応用緩衝液
JP3424504B2 (ja) * 1997-06-24 2003-07-07 三菱化学株式会社 ヒアルロン酸結合タンパク質又はヒアルロン酸の測定方法
AU6059299A (en) * 1998-09-25 2000-04-17 Quest Diagnostics Investments Incorporated Biological assay compositions containing non-interfering, foam-inhibiting and foam-collapsing agents
US6303663B1 (en) * 1999-03-26 2001-10-16 Cognis Corporation Process for making defoaming compositions
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US6610499B1 (en) * 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US7157443B2 (en) * 2001-12-11 2007-01-02 Merck & Co., Inc. Staphylococcus aureus exopolysaccharide and process
US20040101859A1 (en) 2002-11-25 2004-05-27 Cepheid Compositions, methods and kits for polynucleotide amplification reactions and microfluidic devices
US20080050842A1 (en) * 2003-02-15 2008-02-28 Golovlev Valeri V Method of visualization and quanitification of biopolymer molecules immobilized on solid support
US20050037386A1 (en) * 2003-05-05 2005-02-17 Drug Risk Solutions, L.L.C. Composition and processes for analysis of pharmacologic agents in biological samples
JP4338674B2 (ja) * 2005-05-19 2009-10-07 信越化学工業株式会社 消泡剤組成物
GB2464222B (en) * 2006-02-15 2010-07-07 Inverness Medical Switzerland Analysis method
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Also Published As

Publication number Publication date
EP2508885A4 (fr) 2013-05-01
CN102687014A (zh) 2012-09-19
CA2781166A1 (fr) 2011-06-03
CN102687014B (zh) 2017-10-03
EP2508885A1 (fr) 2012-10-10
WO2011065573A1 (fr) 2011-06-03
US20120258552A1 (en) 2012-10-11
JPWO2011065573A1 (ja) 2013-04-18
CN107632147A (zh) 2018-01-26
JP5806939B2 (ja) 2015-11-10
EP2508885B1 (fr) 2017-03-08
KR101826367B1 (ko) 2018-02-06
KR20120113745A (ko) 2012-10-15

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