CA2770771C - Monoclonal antibodies for pbp2-a protein and homologous sequences for treatment of infections and immunodiagnosis on bacteria from phylum firmicutes - Google Patents

Monoclonal antibodies for pbp2-a protein and homologous sequences for treatment of infections and immunodiagnosis on bacteria from phylum firmicutes Download PDF

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Publication number
CA2770771C
CA2770771C CA2770771A CA2770771A CA2770771C CA 2770771 C CA2770771 C CA 2770771C CA 2770771 A CA2770771 A CA 2770771A CA 2770771 A CA2770771 A CA 2770771A CA 2770771 C CA2770771 C CA 2770771C
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CA
Canada
Prior art keywords
seq
mrsa
pbp2a
bacteria
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2770771A
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English (en)
French (fr)
Other versions
CA2770771A1 (en
Inventor
Jose Procopio Moreno Senna
Joao Luiz Sampaio Queiroz
Nadia Maria Batoreu
Maria da Gloria Martins Teixeira
Original Assignee
Oswaldo Cruz Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BRPI0914508-7A external-priority patent/BRPI0914508B1/pt
Application filed by Oswaldo Cruz Foundation filed Critical Oswaldo Cruz Foundation
Priority claimed from PCT/BR2010/000263 external-priority patent/WO2011017791A1/pt
Publication of CA2770771A1 publication Critical patent/CA2770771A1/en
Application granted granted Critical
Publication of CA2770771C publication Critical patent/CA2770771C/en
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2770771A 2009-08-10 2010-08-10 Monoclonal antibodies for pbp2-a protein and homologous sequences for treatment of infections and immunodiagnosis on bacteria from phylum firmicutes Active CA2770771C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BRPI0914508-7A BRPI0914508B1 (pt) 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA
BRPI0914508-7 2009-08-10
PCT/BR2010/000263 WO2011017791A1 (pt) 2009-08-10 2010-08-10 Anticorpos monoclonais para a proteína pbp2-a e sequências homólogas para o tratamento de infeçcões e imunodiagnóstico em bactérias do filo firmicutes

Publications (2)

Publication Number Publication Date
CA2770771A1 CA2770771A1 (en) 2011-02-17
CA2770771C true CA2770771C (en) 2019-12-03

Family

ID=45896895

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2770771A Active CA2770771C (en) 2009-08-10 2010-08-10 Monoclonal antibodies for pbp2-a protein and homologous sequences for treatment of infections and immunodiagnosis on bacteria from phylum firmicutes

Country Status (6)

Country Link
JP (1) JP5785544B2 (enExample)
CN (1) CN102741281B (enExample)
AU (1) AU2010282162B2 (enExample)
CA (1) CA2770771C (enExample)
CU (2) CU24180B1 (enExample)
SG (1) SG178346A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3415160B1 (en) * 2014-03-04 2021-08-18 Klinikum der Universität München Polypeptides derived from enterococcus and their use for vaccination and the generation of therapeutic antibodies
CN105315367B (zh) * 2014-07-29 2019-01-29 广州瑞博奥生物科技有限公司 用于检测耐甲氧西林金黄色葡萄球菌的酶联免疫试剂盒
BR102020016890A2 (pt) * 2020-08-19 2022-05-03 Fundação Oswaldo Cruz Proteina, polinucleotídeo, vetor, célula hospedeira, composição, método para tratar uma doença, método in vitro para prognosticar esclerose múltipla, e, uso de uma proteína ou composição
CN113150139B (zh) * 2021-02-01 2022-09-09 深圳市龙华区疾病预防控制中心 一种PBP2a单克隆抗体及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503015A (ja) * 1999-05-03 2003-01-28 メダレツクス・インコーポレーテツド スタフィロコッカス・アウレウスに対するヒト抗体

Also Published As

Publication number Publication date
CA2770771A1 (en) 2011-02-17
RU2012108941A (ru) 2013-09-20
CN102741281B (zh) 2015-02-25
AU2010282162B2 (en) 2016-06-02
CU20140101A7 (es) 2015-01-29
SG178346A1 (en) 2012-03-29
CU24180B1 (es) 2016-04-25
JP2013501732A (ja) 2013-01-17
AU2010282162A8 (en) 2012-05-24
CN102741281A (zh) 2012-10-17
AU2010282162A1 (en) 2012-04-05
JP5785544B2 (ja) 2015-09-30
CU20120026A7 (es) 2012-06-21
HK1176077A1 (en) 2013-07-19
CU24095B1 (es) 2015-04-29

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