CA2760133A1 - Treatment of neurodegeneration and neuroinflammation - Google Patents
Treatment of neurodegeneration and neuroinflammation Download PDFInfo
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- CA2760133A1 CA2760133A1 CA2760133A CA2760133A CA2760133A1 CA 2760133 A1 CA2760133 A1 CA 2760133A1 CA 2760133 A CA2760133 A CA 2760133A CA 2760133 A CA2760133 A CA 2760133A CA 2760133 A1 CA2760133 A1 CA 2760133A1
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| PCT/US2010/001282 WO2010126605A1 (en) | 2009-04-29 | 2010-04-29 | Treatment of neurodegeneration and neuroinflammation |
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| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| WO2005023241A1 (en) | 2003-09-09 | 2005-03-17 | Fumapharm Ag | The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma |
| SI2801354T1 (sl) * | 2004-10-08 | 2017-07-31 | Forward Pharma A/S | Farmacevtske sestave z nadzorovanim sproščanjem, ki zajemajo ester fumarne kisline |
| DK2653873T3 (da) | 2007-02-08 | 2022-07-25 | Biogen Ma Inc | Sammensætninger og anvendelser til behandling af multipel sklerose |
| PT2139467T (pt) * | 2007-02-08 | 2016-12-16 | Biogen Ma Inc | Neuroproteção em doenças desmielinizantes |
| DK2334378T3 (da) | 2008-08-19 | 2014-07-07 | Xenoport Inc | Prodrugs af methylhydrogenfumarat, farmaceutiske sammensætninger deraf og fremgangsmåder til anvendelse |
| KR101699912B1 (ko) | 2009-01-09 | 2017-01-25 | 포워드 파마 에이/에스 | 1종 이상의 푸마르산 에스테르를 침식 매트릭스에 함유하는 제제 |
| JPWO2010098429A1 (ja) | 2009-02-27 | 2012-09-06 | 国立大学法人大阪大学 | 免疫アジュバント組成物、及びその利用 |
| EP3466420A1 (en) * | 2009-04-29 | 2019-04-10 | Biogen MA Inc. | Dimethyl fumarate for the treatment of friedreich ataxia |
| US20140142095A1 (en) * | 2011-04-28 | 2014-05-22 | Serket Pharma, Llc | Agents useful for treating friedreich's ataxia and other neurodegenerative diseases |
| EP2713724A4 (en) * | 2011-05-26 | 2015-03-11 | Biogen Idec Inc | METHODS OF TREATING MULTIPLE SCLEROSIS AND PRESERVING AND / OR INCREASING MYELINE CONTENT |
| JP6385273B6 (ja) | 2011-06-08 | 2023-12-15 | バイオジェン・エムエイ・インコーポレイテッド | 高純度結晶性ジメチルフマラートの調製方法 |
| HK1202885A1 (en) * | 2011-12-16 | 2015-10-09 | Biogen Ma Inc. | Silicon-containing fumaric acid esters |
| US20130158077A1 (en) | 2011-12-19 | 2013-06-20 | Ares Trading S.A. | Pharmaceutical compositions |
| CN113244185A (zh) * | 2012-02-07 | 2021-08-13 | 比奥根玛公司 | 含有富马酸二甲酯的药物组合物 |
| US20130259856A1 (en) * | 2012-03-27 | 2013-10-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate |
| JP2013220090A (ja) * | 2012-04-19 | 2013-10-28 | Tohoku Univ | 眼疾患治療に使用する薬剤スクリーニング方法 |
| JP2015527372A (ja) * | 2012-08-22 | 2015-09-17 | ゼノポート，インコーポレイティド | 副作用を低減させるモノメチルフマレートおよびそのプロドラッグの投与方法 |
| US20140348915A9 (en) | 2012-08-22 | 2014-11-27 | Xenoport, Inc. | Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof |
| US20140171504A1 (en) | 2012-12-14 | 2014-06-19 | Georgia Regents Research Institute, Inc. | Methods of Treating Sickle Cell Disease and Related Disorders Using Fumaric Acid Esters |
| JP6506174B2 (ja) * | 2012-12-21 | 2019-04-24 | バイオジェン エムエー インコーポレイテッド | 重水素置換されたフマル酸誘導体 |
| CN103173544B (zh) * | 2013-03-05 | 2015-01-28 | 浙江大学 | Leber病之线粒体T3866C检测试剂盒及应用 |
| CN105452213B (zh) | 2013-03-14 | 2017-09-22 | 阿尔克梅斯制药爱尔兰有限公司 | 富马酸酯前体药物及其在治疗多种疾病中的应用 |
| US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
| WO2014160633A1 (en) | 2013-03-24 | 2014-10-02 | Xenoport, Inc. | Pharmaceutical compositions of dimethyl fumarate |
| US9302977B2 (en) | 2013-06-07 | 2016-04-05 | Xenoport, Inc. | Method of making monomethyl fumarate |
| US9421182B2 (en) | 2013-06-21 | 2016-08-23 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| TW201516020A (zh) | 2013-09-06 | 2015-05-01 | Xenoport Inc | （ｎ，ｎ－二乙基胺甲醯基）甲基（２ｅ）丁－２－烯－１，４－二酸甲酯之晶形、合成方法及用途 |
| CN103768045B (zh) * | 2013-10-30 | 2015-10-07 | 苏州大学附属第一医院 | 富马酸二甲酯在制备治疗蛛网膜下腔出血后早期脑损伤药物的应用 |
| US20160310457A1 (en) * | 2013-12-12 | 2016-10-27 | Almirall, S.A. | Pharmaceutical compositions comprising dimethyl fumarate |
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| MA49448A (fr) | 2017-06-23 | 2020-04-29 | Almirall Sa | Compositions pharmaceutiques contenant du fumarate de diméthyle |
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-
2010
- 2010-04-29 EP EP18206136.6A patent/EP3466420A1/en not_active Withdrawn
- 2010-04-29 WO PCT/US2010/001282 patent/WO2010126605A1/en not_active Ceased
- 2010-04-29 JP JP2012508485A patent/JP2012525385A/ja not_active Withdrawn
- 2010-04-29 EP EP17202547.0A patent/EP3318249A1/en not_active Withdrawn
- 2010-04-29 AU AU2010242064A patent/AU2010242064A1/en not_active Abandoned
- 2010-04-29 EP EP10770066A patent/EP2424357A4/en not_active Withdrawn
- 2010-04-29 CN CN2010800215056A patent/CN102427727A/zh active Pending
- 2010-04-29 CA CA2760133A patent/CA2760133A1/en not_active Abandoned
- 2010-04-29 NZ NZ595941A patent/NZ595941A/en not_active IP Right Cessation
- 2010-04-29 NZ NZ617130A patent/NZ617130A/en not_active IP Right Cessation
- 2010-04-29 US US13/266,997 patent/US20120165404A1/en not_active Abandoned
- 2010-04-29 CN CN201410648177.2A patent/CN104523673A/zh active Pending
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2014
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- 2014-11-27 JP JP2014239565A patent/JP2015044855A/ja active Pending
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2016
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2018
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- 2018-11-29 US US16/204,076 patent/US20190195860A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN102427727A (zh) | 2012-04-25 |
| JP2015044855A (ja) | 2015-03-12 |
| JP2012525385A (ja) | 2012-10-22 |
| AU2010242064A1 (en) | 2011-11-17 |
| US20190195860A1 (en) | 2019-06-27 |
| WO2010126605A1 (en) | 2010-11-04 |
| AU2010242064A2 (en) | 2013-10-10 |
| NZ617130A (en) | 2015-06-26 |
| JP2016175926A (ja) | 2016-10-06 |
| NZ595941A (en) | 2014-02-28 |
| CN104523673A (zh) | 2015-04-22 |
| HK1255133A1 (en) | 2019-08-09 |
| EP3466420A1 (en) | 2019-04-10 |
| EP3318249A1 (en) | 2018-05-09 |
| EP2424357A4 (en) | 2012-10-10 |
| EP2424357A1 (en) | 2012-03-07 |
| US20150132747A1 (en) | 2015-05-14 |
| US20120165404A1 (en) | 2012-06-28 |
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