CA2758063C - Method and apparatus for detecting pharmaceuticals in a sample - Google Patents

Method and apparatus for detecting pharmaceuticals in a sample Download PDF

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Publication number
CA2758063C
CA2758063C CA2758063A CA2758063A CA2758063C CA 2758063 C CA2758063 C CA 2758063C CA 2758063 A CA2758063 A CA 2758063A CA 2758063 A CA2758063 A CA 2758063A CA 2758063 C CA2758063 C CA 2758063C
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CA
Canada
Prior art keywords
tau
fluorescence lifetime
sample
fluorescent emission
intensity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2758063A
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English (en)
French (fr)
Other versions
CA2758063A1 (en
Inventor
Ian A. Nicholls
Bjoern C. G. Karlsson
Annika M. Rosengren
Per Ola Andersson
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of CA2758063A1 publication Critical patent/CA2758063A1/en
Application granted granted Critical
Publication of CA2758063C publication Critical patent/CA2758063C/en
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Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2758063A 2009-04-07 2010-03-25 Method and apparatus for detecting pharmaceuticals in a sample Active CA2758063C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0950225-3 2009-04-07
SE0950225A SE533680C2 (sv) 2009-04-07 2009-04-07 Metod och anordning för detektering av läkemedel i ett prov
PCT/SE2010/050326 WO2010117320A1 (en) 2009-04-07 2010-03-25 Method and apparatus for detecting pharmaceuticals in a sample

Publications (2)

Publication Number Publication Date
CA2758063A1 CA2758063A1 (en) 2010-10-14
CA2758063C true CA2758063C (en) 2015-12-15

Family

ID=42262251

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2758063A Active CA2758063C (en) 2009-04-07 2010-03-25 Method and apparatus for detecting pharmaceuticals in a sample

Country Status (7)

Country Link
US (1) US8841633B2 (de)
EP (1) EP2417437B1 (de)
JP (1) JP5596124B2 (de)
AU (1) AU2010235233B2 (de)
CA (1) CA2758063C (de)
SE (1) SE533680C2 (de)
WO (1) WO2010117320A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102650596B (zh) * 2011-02-24 2014-06-18 中国科学技术大学 时间分辨荧光光谱测硼仪控制单元及应用其的测硼方法
DE102011055330B4 (de) * 2011-11-14 2024-10-31 Leica Microsystems Cms Gmbh Verfahren zum Messen der Lebensdauer eines angeregten Zustandes in einer Probe
JP6595204B2 (ja) * 2015-04-24 2019-10-23 株式会社島津製作所 光学分析装置
EP3729055B1 (de) 2017-12-22 2025-11-05 Radiometer Medical ApS Verfahren und sensor zum erfassen des vorhandenseins oder fehlens einer verunreinigung
JP7633102B2 (ja) * 2021-06-22 2025-02-19 浜松ホトニクス株式会社 蛍光寿命計測のバックグラウンド除去方法及び標的物質の定量方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61241639A (ja) * 1985-04-19 1986-10-27 Hitachi Ltd 反応試料分析装置
US6046051A (en) * 1997-06-27 2000-04-04 Hemosense, Inc. Method and device for measuring blood coagulation or lysis by viscosity changes
DE19955607A1 (de) * 1999-11-19 2001-06-07 November Ag Molekulare Medizin Medikament oder aufeinander abgestimmte Kombination von Medikamenten
JP4459390B2 (ja) * 2000-06-08 2010-04-28 浜松ホトニクス株式会社 蛍光測定方法、蛍光測定装置及びそれを用いた試料評価装置
JP2004090517A (ja) * 2002-09-02 2004-03-25 Seiko Epson Corp 印刷装置およびカートリッジ
WO2005001451A2 (en) * 2003-02-24 2005-01-06 Cdex, Inc. System and methods for detection and identification of chemical substances
EP1612541A1 (de) 2003-04-04 2006-01-04 National Institute of Advanced Industrial Science and Technology Quantitatives reaktionsmittel, verfahren und geräte einer substanz unter verwendung der fluoreszenzlebensdauer
CN1879020B (zh) 2003-09-03 2010-11-03 受体有限责任公司 使用组合的人工受体的传感器
JP2007033159A (ja) 2005-07-25 2007-02-08 Assay Corp 蛍光分子で標識された測定対象物質

Also Published As

Publication number Publication date
AU2010235233A1 (en) 2011-11-03
SE0950225A1 (sv) 2010-10-08
WO2010117320A1 (en) 2010-10-14
SE533680C2 (sv) 2010-11-30
EP2417437B1 (de) 2013-07-03
AU2010235233B2 (en) 2013-11-28
EP2417437A1 (de) 2012-02-15
CA2758063A1 (en) 2010-10-14
JP5596124B2 (ja) 2014-09-24
US8841633B2 (en) 2014-09-23
US20120032095A1 (en) 2012-02-09
JP2012523006A (ja) 2012-09-27

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Legal Events

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Effective date: 20150204

H11 Ip right ceased following rejected request for revival

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Effective date: 20240927

H11 Ip right ceased following rejected request for revival

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