CA2757019C - Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide - Google Patents

Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide Download PDF

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Publication number
CA2757019C
CA2757019C CA2757019A CA2757019A CA2757019C CA 2757019 C CA2757019 C CA 2757019C CA 2757019 A CA2757019 A CA 2757019A CA 2757019 A CA2757019 A CA 2757019A CA 2757019 C CA2757019 C CA 2757019C
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CA
Canada
Prior art keywords
compound
pharmaceutically acceptable
dose
trifluoro
pyridin
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CA2757019A
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English (en)
French (fr)
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CA2757019A1 (en
Inventor
Alison Pilgrim
James F. White
Nadia M. J. Rupniak
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Colucid Pharmaceuticals Inc
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Colucid Pharmaceuticals Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42826711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2757019(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Colucid Pharmaceuticals Inc filed Critical Colucid Pharmaceuticals Inc
Publication of CA2757019A1 publication Critical patent/CA2757019A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/10—Energy storage using batteries

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA2757019A 2009-04-02 2010-04-02 Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide Active CA2757019C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16609709P 2009-04-02 2009-04-02
US61/166,097 2009-04-02
PCT/US2010/029810 WO2010115125A2 (en) 2009-04-02 2010-04-02 Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide

Publications (2)

Publication Number Publication Date
CA2757019A1 CA2757019A1 (en) 2010-10-07
CA2757019C true CA2757019C (en) 2018-05-15

Family

ID=42826711

Family Applications (1)

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CA2757019A Active CA2757019C (en) 2009-04-02 2010-04-02 Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide

Country Status (26)

Country Link
US (3) US20100256187A1 (https=)
EP (1) EP2413933B2 (https=)
JP (9) JP5727457B2 (https=)
KR (1) KR101697801B1 (https=)
CN (2) CN107412230A (https=)
AU (1) AU2010232497B2 (https=)
CA (1) CA2757019C (https=)
CY (2) CY1119785T1 (https=)
DK (1) DK2413933T4 (https=)
ES (1) ES2655881T5 (https=)
FI (1) FIC20230001I1 (https=)
FR (1) FR23C1002I2 (https=)
HK (1) HK1243923A1 (https=)
HR (1) HRP20171742T4 (https=)
HU (2) HUE037261T2 (https=)
IL (1) IL215483A (https=)
LT (2) LT2413933T (https=)
LU (1) LUC00295I2 (https=)
MX (1) MX2011010359A (https=)
NL (1) NL301214I2 (https=)
NO (2) NO2413933T3 (https=)
NZ (1) NZ596161A (https=)
PL (1) PL2413933T5 (https=)
PT (1) PT2413933T (https=)
SI (1) SI2413933T2 (https=)
WO (1) WO2010115125A2 (https=)

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US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
CA2916885A1 (en) 2013-06-26 2014-12-31 Nexisvision, Inc. Contact lenses for refractive correction
KR20190075130A (ko) 2016-12-06 2019-06-28 코루시드 파마슈티컬즈 인코포레이티드 피리디노일피페리딘 5-ht1f 작용제에 관한 조성물 및 방법
TWI826514B (zh) 2018-09-04 2023-12-21 美商美國禮來大藥廠 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh) 2019-07-09 2022-09-01 美商美國禮來大藥廠 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

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TWI754772B (zh) 2017-09-06 2022-02-11 美商美國禮來大藥廠 用於治療偏頭痛之拉米迪坦(lasmiditan)與cgrp拮抗劑之組合療法
TWI826514B (zh) 2018-09-04 2023-12-21 美商美國禮來大藥廠 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh) 2019-07-09 2022-09-01 美商美國禮來大藥廠 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

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Publication number Publication date
US12257246B2 (en) 2025-03-25
FR23C1002I2 (fr) 2023-11-24
EP2413933B1 (en) 2017-11-01
JP2023175694A (ja) 2023-12-12
JP6887462B2 (ja) 2021-06-16
HRP20171742T1 (hr) 2018-02-09
JP2018087247A (ja) 2018-06-07
EP2413933A4 (en) 2012-09-19
HUS2300004I1 (hu) 2023-02-28
SI2413933T1 (en) 2018-04-30
JP7566996B2 (ja) 2024-10-15
LUC00295I2 (https=) 2025-09-22
CY1119785T1 (el) 2018-06-27
FIC20230001I1 (fi) 2023-01-10
US20250228839A1 (en) 2025-07-17
JP7335397B2 (ja) 2023-08-29
PL2413933T3 (pl) 2018-04-30
JP2012522805A (ja) 2012-09-27
DK2413933T3 (da) 2018-01-29
MX2011010359A (es) 2012-02-23
EP2413933A2 (en) 2012-02-08
US20210401822A1 (en) 2021-12-30
AU2010232497A1 (en) 2011-11-24
DK2413933T4 (da) 2021-08-23
CY2023001I1 (el) 2023-03-24
KR20110136893A (ko) 2011-12-21
NO2023002I1 (no) 2023-01-05
EP2413933B2 (en) 2021-06-09
WO2010115125A3 (en) 2011-02-17
JP2022163049A (ja) 2022-10-25
JP2021152008A (ja) 2021-09-30
US20100256187A1 (en) 2010-10-07
CN107412230A (zh) 2017-12-01
PT2413933T (pt) 2017-12-12
IL215483A (en) 2017-07-31
WO2010115125A2 (en) 2010-10-07
LTC2413933I2 (https=) 2025-03-10
JP2016188241A (ja) 2016-11-04
JP7110446B2 (ja) 2022-08-01
ES2655881T3 (es) 2018-02-22
JP2025020117A (ja) 2025-02-12
LT2413933T (lt) 2018-02-26
JP2015013903A (ja) 2015-01-22
JP5727457B2 (ja) 2015-06-03
HUE037261T2 (hu) 2018-08-28
KR101697801B1 (ko) 2017-01-18
PL2413933T5 (pl) 2021-10-18
CA2757019A1 (en) 2010-10-07
NL301214I1 (https=) 2023-01-25
NL301214I2 (nl) 2023-04-19
LTPA2023502I1 (https=) 2023-01-25
AU2010232497B2 (en) 2016-05-19
IL215483A0 (en) 2011-12-29
FR23C1002I1 (fr) 2023-03-10
HK1243923A1 (zh) 2018-07-27
CY2023001I2 (el) 2023-06-09
HRP20171742T4 (hr) 2021-08-06
CN102753171A (zh) 2012-10-24
ES2655881T5 (es) 2021-11-25
SI2413933T2 (sl) 2021-09-30
NO2413933T3 (https=) 2018-03-31
JP2019189617A (ja) 2019-10-31
NZ596161A (en) 2013-11-29

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