ATE252572T1 - 5-ht1f agonisten - Google Patents
5-ht1f agonistenInfo
- Publication number
- ATE252572T1 ATE252572T1 AT99931907T AT99931907T ATE252572T1 AT E252572 T1 ATE252572 T1 AT E252572T1 AT 99931907 T AT99931907 T AT 99931907T AT 99931907 T AT99931907 T AT 99931907T AT E252572 T1 ATE252572 T1 AT E252572T1
- Authority
- AT
- Austria
- Prior art keywords
- ht1f agonists
- ht1f
- agonists
- mammal
- activating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9119898P | 1998-06-30 | 1998-06-30 | |
| PCT/US1999/014400 WO2000000487A1 (en) | 1998-06-30 | 1999-06-25 | 5-ht1f agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE252572T1 true ATE252572T1 (de) | 2003-11-15 |
Family
ID=22226571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99931907T ATE252572T1 (de) | 1998-06-30 | 1999-06-25 | 5-ht1f agonisten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6358972B1 (de) |
| EP (1) | EP1089993B1 (de) |
| JP (1) | JP2002519348A (de) |
| AT (1) | ATE252572T1 (de) |
| AU (1) | AU4831899A (de) |
| CA (1) | CA2336254A1 (de) |
| DE (1) | DE69912279T2 (de) |
| ES (1) | ES2209462T3 (de) |
| WO (1) | WO2000000487A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696439B1 (en) * | 1999-02-26 | 2004-02-24 | Eli Lilly And Company | 5-HT1F agonists |
| US7211594B2 (en) | 2000-07-31 | 2007-05-01 | Signal Pharmaceuticals, Llc | Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith |
| US6897231B2 (en) | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
| DK1330452T3 (da) * | 2000-09-20 | 2009-03-16 | Ortho Mcneil Janssen Pharm | Pyrazinderivater som modulatorer af tyrosinkinaser |
| KR20040007497A (ko) * | 2001-04-16 | 2004-01-24 | 에자이 가부시키가이샤 | 신규 1ｈ-인다졸 화합물 |
| WO2003014118A1 (en) * | 2001-08-08 | 2003-02-20 | Pharmacia & Upjohn Company | THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| MXPA05011223A (es) * | 2003-04-18 | 2006-01-26 | Lilly Co Eli | Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif. |
| UA82711C2 (en) | 2003-09-12 | 2008-05-12 | Эли Лилли Энд Компани | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists |
| JP2007516266A (ja) | 2003-12-17 | 2007-06-21 | イーライ リリー アンド カンパニー | ５−ｈｔ１ｆアゴニストとしての置換（４−アミノシクロヘキセン−１−イル）フェニルおよび（４−アミノシクロヘキセン−１−イル）ピリジニル化合物 |
| PE20060373A1 (es) | 2004-06-24 | 2006-04-29 | Smithkline Beecham Corp | Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2 |
| KR20130136010A (ko) | 2005-04-13 | 2013-12-11 | 네우렉슨 인코포레이티드 | Ｎｏｓ 저해 활성을 갖는 치환된 인돌 화합물 |
| US8063071B2 (en) | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
| JP5350219B2 (ja) | 2006-04-13 | 2013-11-27 | ニューラクソン，インコーポレーテッド | Ｎｏｓ阻害活性を有する１，５および３，６−置換インドール化合物 |
| PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
| KR20100103799A (ko) | 2007-11-16 | 2010-09-28 | 네우렉슨 인코포레이티드 | 내장통을 치료하기 위한 인돌 화합물 및 방법 |
| CA2720215C (en) | 2008-04-16 | 2018-02-27 | Karo Bio Ab | Estrogen receptor ligands |
| WO2010102968A1 (en) | 2009-03-10 | 2010-09-16 | Glaxo Group Limited | Indole derivatives as ikk2 inhibitors |
| WO2011123654A1 (en) | 2010-04-02 | 2011-10-06 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists |
| EP2796456A1 (de) * | 2010-12-09 | 2014-10-29 | Amgen Inc. | Bicyclische Verbindungen als PIM-Hemmer |
| US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
| US9321756B2 (en) | 2011-03-22 | 2016-04-26 | Amgen Inc. | Azole compounds as PIM inhibitors |
| GB201113538D0 (en) | 2011-08-04 | 2011-09-21 | Karobio Ab | Novel estrogen receptor ligands |
| SG10201806809QA (en) | 2015-02-11 | 2018-09-27 | Sunovion Pharmaceuticals Inc | 1-heterocyclyl isochromanyl compounds and analogs for treating cns disorders |
| JP2019523279A (ja) | 2016-07-29 | 2019-08-22 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 化合物および組成物ならびにそれらの使用 |
| US10196403B2 (en) | 2016-07-29 | 2019-02-05 | Sunovion Pharmaceuticals Inc. | Compounds and compositions and uses thereof |
| BR112020001433A2 (pt) | 2017-08-02 | 2020-07-28 | Sunovion Pharmaceuticals Inc. | compostos de isocromano e usos dos mesmos |
| US11136304B2 (en) | 2019-03-14 | 2021-10-05 | Sunovion Pharmaceuticals Inc. | Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
| AR119319A1 (es) | 2019-07-09 | 2021-12-09 | Lilly Co Eli | Procesos e intermediario para la preparación a gran escala de hemisuccinato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida y preparación de acetato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| EP0494774A1 (de) * | 1991-01-11 | 1992-07-15 | MERCK SHARP & DOHME LTD. | Indazol-substituierte 5-Kettenglieder heteroaromatische Verbindungen |
| TW263508B (de) | 1991-02-12 | 1995-11-21 | Pfizer | |
| GB9226537D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| GB9407447D0 (en) * | 1994-04-14 | 1994-06-08 | Glaxo Group Ltd | Chemical compounds |
-
1999
- 1999-06-25 JP JP2000557248A patent/JP2002519348A/ja not_active Withdrawn
- 1999-06-25 EP EP99931907A patent/EP1089993B1/de not_active Expired - Lifetime
- 1999-06-25 AU AU48318/99A patent/AU4831899A/en not_active Abandoned
- 1999-06-25 DE DE69912279T patent/DE69912279T2/de not_active Expired - Fee Related
- 1999-06-25 CA CA002336254A patent/CA2336254A1/en not_active Abandoned
- 1999-06-25 WO PCT/US1999/014400 patent/WO2000000487A1/en active IP Right Grant
- 1999-06-25 US US09/701,934 patent/US6358972B1/en not_active Expired - Fee Related
- 1999-06-25 AT AT99931907T patent/ATE252572T1/de not_active IP Right Cessation
- 1999-06-25 ES ES99931907T patent/ES2209462T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002519348A (ja) | 2002-07-02 |
| ES2209462T3 (es) | 2004-06-16 |
| US6358972B1 (en) | 2002-03-19 |
| AU4831899A (en) | 2000-01-17 |
| EP1089993A1 (de) | 2001-04-11 |
| CA2336254A1 (en) | 2000-01-06 |
| DE69912279D1 (de) | 2003-11-27 |
| DE69912279T2 (de) | 2004-07-29 |
| EP1089993B1 (de) | 2003-10-22 |
| WO2000000487A1 (en) | 2000-01-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE252572T1 (de) | 5-ht1f agonisten | |
| NO2017022I1 (no) | Obeticholinsyre | |
| ATE377000T1 (de) | 5-ht1f agonisten | |
| ATE273305T1 (de) | Thrombin-inhibitoren | |
| EA200200619A1 (ru) | Непептидильные ингибиторы vla-4-зависимого связывания клеток, применяемые при лечении воспалительных, аутоимунных и респираторных заболеваний | |
| DK0850221T3 (da) | Meta-guanidin-, urinstof-, thiourinstof- eller azacykliske aminobenzoesyrederivater som intergrinantagonister | |
| EA200100203A1 (ru) | Производные 4,4-биарилпиперидина с активностью в отношении опиоидных рецепторов | |
| MY123908A (en) | Meta-azacyclic amino benzoic acid compounds and derivatives thereof | |
| EA200000871A1 (ru) | Ингибиторы фосфолипазных ферментов | |
| BR9907300A (pt) | Inibidores do fator xa oxoaza-heterociclila substituìdos | |
| BR9913592A (pt) | Compostos, processo de preparação dos compostos, e, composições farmacêuticas | |
| TNSN02008A1 (fr) | Derives d'acides isophtalique nouveaux inhibiteurs de mmp, et compositions les contenant | |
| ATE284879T1 (de) | Indazol-derivate als 5-ht1f agonists | |
| BR0108816A (pt) | Derivados de quinolina como antagonistas alfa-2 | |
| BR0313846A (pt) | Derivados de dioxano-2-alquilcarbamatos, sua preparação e sua aplicação em terapêutica | |
| PT1250340E (pt) | Metodos e compostos para inibicao de mrp1 | |
| ES2011919A6 (es) | Metodo para producir compuestos antagonistas de los leucotrienos. | |
| WO2000000490A3 (en) | 5-ht1f agonists | |
| TR200103680T2 (tr) | IL-8 reseptör antagonistleri. | |
| HU9800970D0 (en) | Process for producing pharmaceutical compositions containing heptapeptide somatostatin derivatives of neurogene- and non-neurogene-antiflogistic and analgesic activity and peptidomimetica | |
| BR9915692A (pt) | Monohidrato de bromidrato de eletriptano | |
| NO20014127L (no) | 5-HT1F agonister | |
| TR200103561T2 (tr) | Rodanin türevleri ve amiloidlerin önlenmesi ve görüntülenmesinde kullanımları | |
| DE69524064D1 (de) | Indan-2-mercaptoacetylamid disulfidderivate als enkephalinase inhibitoren | |
| YU43499A (sh) | Kristalna hidratovana natrijumova so (e)-4,6-dihloro-3- (2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |