CY1119785T1 - 2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου - Google Patents

2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου

Info

Publication number
CY1119785T1
CY1119785T1 CY20171101243T CY171101243T CY1119785T1 CY 1119785 T1 CY1119785 T1 CY 1119785T1 CY 20171101243 T CY20171101243 T CY 20171101243T CY 171101243 T CY171101243 T CY 171101243T CY 1119785 T1 CY1119785 T1 CY 1119785T1
Authority
CY
Cyprus
Prior art keywords
benzamide
trifluoro
pyridin
methyl
piperidino
Prior art date
Application number
CY20171101243T
Other languages
English (en)
Inventor
Alison Pilgrim
James F. White
Nadia M. J. Rupniak
Original Assignee
Colucid Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42826711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119785(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Colucid Pharmaceuticals, Inc. filed Critical Colucid Pharmaceuticals, Inc.
Publication of CY1119785T1 publication Critical patent/CY1119785T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/10—Energy storage using batteries

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με και γνωστοποιεί μία φαρμακευτική σύνθεση 2,4,6-τριφθορο-Ν-[6-(1-μεθυλο-πιπεριδιν-4-υλοκαρβονυλο)-πυριδιν-2-υλο]-βενζαμιδίου και ενός φαρμακευτικώς αποδεκτού φορέα.
CY20171101243T 2009-04-02 2017-11-27 2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου CY1119785T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16609709P 2009-04-02 2009-04-02
PCT/US2010/029810 WO2010115125A2 (en) 2009-04-02 2010-04-02 Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide

Publications (1)

Publication Number Publication Date
CY1119785T1 true CY1119785T1 (el) 2018-06-27

Family

ID=42826711

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20171101243T CY1119785T1 (el) 2009-04-02 2017-11-27 2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου
CY2023001C CY2023001I2 (el) 2009-04-02 2023-01-10 2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2023001C CY2023001I2 (el) 2009-04-02 2023-01-10 2,4,6-τριφθορο-ν-[6-(1-μεθυλο-πιπεριδινο-4-καρβονυλο)-πυριδιν-2-υλο]-βενζαμιδιο για την αντιμετωπιση ημικρανιας μεσω της στοματικης ή της ενδοφλεβιας οδου

Country Status (25)

Country Link
US (2) US20100256187A1 (el)
EP (1) EP2413933B2 (el)
JP (8) JP5727457B2 (el)
KR (1) KR101697801B1 (el)
CN (2) CN102753171A (el)
AU (1) AU2010232497B2 (el)
CA (1) CA2757019C (el)
CY (2) CY1119785T1 (el)
DK (1) DK2413933T4 (el)
ES (1) ES2655881T5 (el)
FI (1) FIC20230001I1 (el)
FR (1) FR23C1002I2 (el)
HK (1) HK1243923A1 (el)
HR (1) HRP20171742T4 (el)
HU (2) HUE037261T2 (el)
IL (1) IL215483A (el)
LT (2) LT2413933T (el)
MX (1) MX2011010359A (el)
NL (1) NL301214I2 (el)
NO (2) NO2413933T3 (el)
NZ (1) NZ596161A (el)
PL (1) PL2413933T5 (el)
PT (1) PT2413933T (el)
SI (1) SI2413933T2 (el)
WO (1) WO2010115125A2 (el)

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TWI263497B (en) 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
US9943401B2 (en) 2008-04-04 2018-04-17 Eugene de Juan, Jr. Therapeutic device for pain management and vision
NZ596161A (en) * 2009-04-02 2013-11-29 Colucid Pharmaceuticals Inc Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide
US8697876B2 (en) 2010-04-02 2014-04-15 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
EP3014345A2 (en) 2013-06-26 2016-05-04 Nexisvision, Inc. Contact lenses for refractive correction
TN2019000174A1 (en) * 2016-12-06 2020-10-05 Colucid Pharmaceuticals Inc Compositions and methods related to pyridinoylpiperidine 5-ht1f agonists
TWI826514B (zh) * 2018-09-04 2023-12-21 美商美國禮來大藥廠 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh) 2019-07-09 2022-09-01 美商美國禮來大藥廠 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

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Also Published As

Publication number Publication date
CN102753171A (zh) 2012-10-24
JP7110446B2 (ja) 2022-08-01
PL2413933T3 (pl) 2018-04-30
JP2023175694A (ja) 2023-12-12
FIC20230001I1 (fi) 2023-01-10
US20210401822A1 (en) 2021-12-30
EP2413933B2 (en) 2021-06-09
DK2413933T4 (da) 2021-08-23
CY2023001I1 (el) 2023-03-24
KR101697801B1 (ko) 2017-01-18
AU2010232497A1 (en) 2011-11-24
WO2010115125A3 (en) 2011-02-17
CA2757019C (en) 2018-05-15
ES2655881T3 (es) 2018-02-22
EP2413933A4 (en) 2012-09-19
HK1243923A1 (zh) 2018-07-27
HUE037261T2 (hu) 2018-08-28
IL215483A (en) 2017-07-31
JP7566996B2 (ja) 2024-10-15
JP2016188241A (ja) 2016-11-04
IL215483A0 (en) 2011-12-29
SI2413933T2 (sl) 2021-09-30
US20100256187A1 (en) 2010-10-07
JP2022163049A (ja) 2022-10-25
JP2018087247A (ja) 2018-06-07
CA2757019A1 (en) 2010-10-07
LT2413933T (lt) 2018-02-26
JP2015013903A (ja) 2015-01-22
ES2655881T5 (es) 2021-11-25
NO2413933T3 (el) 2018-03-31
EP2413933B1 (en) 2017-11-01
CN107412230A (zh) 2017-12-01
NL301214I2 (nl) 2023-04-19
DK2413933T3 (da) 2018-01-29
EP2413933A2 (en) 2012-02-08
PL2413933T5 (pl) 2021-10-18
JP2012522805A (ja) 2012-09-27
HRP20171742T4 (hr) 2021-08-06
SI2413933T1 (en) 2018-04-30
WO2010115125A2 (en) 2010-10-07
JP7335397B2 (ja) 2023-08-29
NL301214I1 (el) 2023-01-25
HUS2300004I1 (hu) 2023-02-28
FR23C1002I1 (fr) 2023-03-10
MX2011010359A (es) 2012-02-23
HRP20171742T1 (hr) 2018-02-09
KR20110136893A (ko) 2011-12-21
JP2021152008A (ja) 2021-09-30
JP2019189617A (ja) 2019-10-31
PT2413933T (pt) 2017-12-12
LTPA2023502I1 (el) 2023-01-25
NO2023002I1 (no) 2023-01-05
JP5727457B2 (ja) 2015-06-03
FR23C1002I2 (fr) 2023-11-24
JP6887462B2 (ja) 2021-06-16
NZ596161A (en) 2013-11-29
CY2023001I2 (el) 2023-06-09
AU2010232497B2 (en) 2016-05-19

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