CA2738024A1 - Methods for purification of viruses - Google Patents
Methods for purification of viruses Download PDFInfo
- Publication number
- CA2738024A1 CA2738024A1 CA2738024A CA2738024A CA2738024A1 CA 2738024 A1 CA2738024 A1 CA 2738024A1 CA 2738024 A CA2738024 A CA 2738024A CA 2738024 A CA2738024 A CA 2738024A CA 2738024 A1 CA2738024 A1 CA 2738024A1
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- Prior art keywords
- virus
- cells
- cell
- viruses
- specific embodiment
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Classifications
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61P31/14—Antivirals for RNA viruses
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- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16051—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| KR102113512B1 (ko) * | 2010-06-01 | 2020-05-22 | 노파르티스 아게 | 동결건조하지 않는 인플루엔자 백신 항원의 농축 |
| US9029517B2 (en) | 2010-07-30 | 2015-05-12 | Emd Millipore Corporation | Chromatography media and method |
| US8895291B2 (en) | 2010-10-08 | 2014-11-25 | Terumo Bct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| EP3147355B1 (en) * | 2010-12-27 | 2020-07-22 | Kyowa Kirin Co., Ltd. | Method for preparing aqueous solution containing culture medium and chelating agent |
| CN102199198A (zh) * | 2011-03-28 | 2011-09-28 | 北京交通大学 | 人呼吸道合胞病毒f蛋白的纯化方法 |
| RU2565827C2 (ru) * | 2011-07-20 | 2015-10-20 | Эбботт Байолоджикалз Б.В. | Способ получения вирусного антигена и вакцин |
| JP6612227B2 (ja) | 2013-11-16 | 2019-11-27 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| JP6661547B2 (ja) * | 2014-05-13 | 2020-03-11 | アムジエン・インコーポレーテツド | フィルタ及び濾過プロセスで用いるためのプロセス制御システム及び方法 |
| US10449517B2 (en) | 2014-09-02 | 2019-10-22 | Emd Millipore Corporation | High surface area fiber media with nano-fibrillated surface features |
| WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
| US20170298091A1 (en) | 2014-12-08 | 2017-10-19 | Emd Millipore Corporation | Mixed Bed Ion Exchange Adsorber |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| US20180273909A1 (en) * | 2015-09-22 | 2018-09-27 | Sanofi Pasteur Biologics, Llc | Purification of respiratory syncytial virus |
| CN106337045A (zh) * | 2016-05-24 | 2017-01-18 | 微基生物科技（上海）有限公司 | 一种防止pcr污染的方法及其应用 |
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| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11268071B2 (en) | 2017-03-30 | 2022-03-08 | Merck Sharp And Dohme Corp. | Addition of nucleases directly to cell culture to facilitate digestion and clearance of host cell nucleic acids |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
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| CA3079151A1 (en) | 2017-10-16 | 2019-04-25 | Serum Institute Of India Private Limited | Stable vaccine compositions comprising inter alia live attenuated recombinant flavivirus and process for preparation thereof |
| WO2019092084A1 (en) * | 2017-11-08 | 2019-05-16 | Blue Sky Vaccines Gmbh | So3 chromatography for use in a method for virus purification |
| US20200390877A1 (en) * | 2017-12-07 | 2020-12-17 | Merck Sharp & Dohme Corp. | Formulations of dengue virus vaccine compositions |
| US10988726B2 (en) | 2018-08-19 | 2021-04-27 | Cytera Cellworks Limited | Systems and methods for automated cell culturing |
| DE102018215551A1 (de) * | 2018-09-12 | 2020-03-12 | Virolutions Biotech Gmbh | Verfahren zur Herstellung eines antitumoralen Arenavirus sowie Arenavirusmutanten |
| CN113330111A (zh) * | 2018-11-21 | 2021-08-31 | 西方溶瘤细胞有限公司 | 病毒的制造 |
| CN111763661B (zh) * | 2019-04-02 | 2022-07-29 | 普莱柯生物工程股份有限公司 | 一种病毒纯化的方法、制备的疫苗组合物及其应用 |
| WO2021180943A1 (en) * | 2020-03-12 | 2021-09-16 | Bavarian Nordic A/S | Compositions improving poxvirus stability |
| JP2023528776A (ja) * | 2020-06-11 | 2023-07-06 | ２セブンティ バイオ インコーポレイテッド | ウイルスベクターの製造方法 |
| WO2021257841A1 (en) * | 2020-06-17 | 2021-12-23 | Meissa Vaccines, Inc. | Chimeric rsv and coronavirus proteins, immunogenic compositions, and methods of use |
| GB2619893A (en) | 2021-03-23 | 2023-12-20 | Terumo Bct Inc | Cell capture and expansion |
| JP7716233B2 (ja) * | 2021-05-28 | 2025-07-31 | ダイセン・メンブレン・システムズ株式会社 | 微小有用物質の分離精製方法と分離精製装置 |
| CN113930353B (zh) * | 2021-08-31 | 2023-07-07 | 广西大学 | 一种耐亚硒酸盐的粘质沙雷氏菌及其还原特性鉴定方法 |
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| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
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| CN115505571B (zh) * | 2022-11-24 | 2023-03-10 | 上海倍谙基生物科技有限公司 | 适用于悬浮培养lmh细胞生产禽腺病毒的无血清添加剂 |
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| KR101464783B1 (ko) | 2006-09-15 | 2014-11-26 | 메디뮨 엘엘씨 | 높은 역가로 바이러스 증식을 지원하는 ｍｄｃｋ 세포주 및 이를 이용한 생물반응기 공정 |
| KR20110074563A (ko) | 2008-09-24 | 2011-06-30 | 메디뮨 엘엘씨 | 바이러스의 정제 방법 |
| KR20110074564A (ko) | 2008-09-24 | 2011-06-30 | 메디뮨 엘엘씨 | 세포 배양, 바이러스 증식 및 바이러스 정제를 위한 방법 |
-
2009
- 2009-09-24 KR KR1020117009305A patent/KR20110074563A/ko not_active Abandoned
- 2009-09-24 JP JP2011529214A patent/JP5548207B2/ja active Active
- 2009-09-24 AU AU2009296628A patent/AU2009296628B2/en not_active Ceased
- 2009-09-24 BR BRPI0919250A patent/BRPI0919250A2/pt not_active IP Right Cessation
- 2009-09-24 EP EP09816835A patent/EP2334328A4/en not_active Withdrawn
- 2009-09-24 CN CN2009801468459A patent/CN102215865B/zh not_active Expired - Fee Related
- 2009-09-24 US US13/120,638 patent/US8785173B2/en active Active
- 2009-09-24 WO PCT/US2009/058174 patent/WO2010036774A1/en not_active Ceased
- 2009-09-24 CA CA2738024A patent/CA2738024A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120219588A1 (en) | 2012-08-30 |
| JP5548207B2 (ja) | 2014-07-16 |
| BRPI0919250A2 (pt) | 2015-12-15 |
| CN102215865A (zh) | 2011-10-12 |
| EP2334328A1 (en) | 2011-06-22 |
| AU2009296628B2 (en) | 2015-01-15 |
| JP2012503489A (ja) | 2012-02-09 |
| US8785173B2 (en) | 2014-07-22 |
| AU2009296628A1 (en) | 2010-04-01 |
| EP2334328A4 (en) | 2012-08-29 |
| CN102215865B (zh) | 2013-10-30 |
| WO2010036774A1 (en) | 2010-04-01 |
| KR20110074563A (ko) | 2011-06-30 |
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