MX2014000753A - Procedimiento para producir antigeno viral y vacunas. - Google Patents

Procedimiento para producir antigeno viral y vacunas.

Info

Publication number
MX2014000753A
MX2014000753A MX2014000753A MX2014000753A MX2014000753A MX 2014000753 A MX2014000753 A MX 2014000753A MX 2014000753 A MX2014000753 A MX 2014000753A MX 2014000753 A MX2014000753 A MX 2014000753A MX 2014000753 A MX2014000753 A MX 2014000753A
Authority
MX
Mexico
Prior art keywords
viral antigen
enveloped virus
vaccines
producing viral
fluid
Prior art date
Application number
MX2014000753A
Other languages
English (en)
Inventor
Yi-Qing Cui
Yiding Wang
Jo Thus
Hof Ron Van T
Sabah Shaker
Geertje Jacoba Van Rooij
Original Assignee
Abbott Biologicals Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Biologicals Bv filed Critical Abbott Biologicals Bv
Publication of MX2014000753A publication Critical patent/MX2014000753A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención pertenece al campo de la industria farmacéutica y se relaciona con un método para la producción de antígeno viral derivado de virus encapsulado, que comprende los pasos de proporcionar un fluido que comprende virus encapsulado, clarificar el fluido que comprende dicho virus encapsulado, reducir el volumen de la cosecha líquida obtenida, solubilizar el virus encapsulado y purificar el antígeno viral; la presente invención además se refiere al uso de dicho método para la producción de una preparación de vacuna.
MX2014000753A 2011-07-20 2012-07-04 Procedimiento para producir antigeno viral y vacunas. MX2014000753A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161509630P 2011-07-20 2011-07-20
EP11174660 2011-07-20
PCT/EP2012/063045 WO2013010797A1 (en) 2011-07-20 2012-07-04 Process for producing viral antigen and vaccines

Publications (1)

Publication Number Publication Date
MX2014000753A true MX2014000753A (es) 2014-05-07

Family

ID=45094875

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000753A MX2014000753A (es) 2011-07-20 2012-07-04 Procedimiento para producir antigeno viral y vacunas.

Country Status (12)

Country Link
EP (1) EP2734619B1 (es)
JP (1) JP6275641B2 (es)
KR (2) KR20140038530A (es)
CN (1) CN103827296B (es)
AU (1) AU2012286098C1 (es)
BR (1) BR112014001049A2 (es)
CA (1) CA2841604C (es)
ES (1) ES2653197T3 (es)
MX (1) MX2014000753A (es)
RU (1) RU2565827C2 (es)
TW (1) TW201311896A (es)
WO (1) WO2013010797A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524563A (zh) * 2014-12-12 2015-04-22 普莱柯生物工程股份有限公司 疫苗组合物及其制备方法和应用
CA3085885A1 (en) 2017-12-19 2019-06-27 CSL Behring Lengnau AG Protein purification and virus inactivation with alkyl glycosides
CN112566494B (zh) 2018-06-12 2023-05-23 Kbio控股有限公司 病毒和抗原纯化和偶联
US11690907B2 (en) 2018-06-12 2023-07-04 Kbio Holdings Limited Vaccines formed by virus and antigen conjugation
US11696948B2 (en) 2018-06-12 2023-07-11 Kbio Holdings Limited Vaccines formed by virus and antigen conjugation
US11529413B2 (en) 2018-06-12 2022-12-20 Kbio Holdings Limited Virus and antigen purification and conjugation
US11999975B2 (en) * 2018-07-04 2024-06-04 Probiogen Ag Method for purifying an enveloped virus
RU2710239C1 (ru) * 2019-06-14 2019-12-25 Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства Способ получения антигена или антигенов для производства противогриппозной вакцины и вакцина на его основе
KR102546626B1 (ko) * 2020-04-29 2023-06-21 에스케이바이오사이언스(주) 인플루엔자 바이러스 항원 정제 조건 신속 확인 시험
AU2021264292A1 (en) * 2020-04-29 2022-12-08 Sk Bioscience Co., Ltd. Influenza virus production method using single-use culture process system and rapid confirmation test of influenza virus antigen purification condition
CN112309502B (zh) * 2020-10-14 2024-09-20 深圳市新合生物医疗科技有限公司 一种计算肿瘤新抗原负荷的方法及系统
JP2023141423A (ja) * 2022-03-24 2023-10-05 国立大学法人 東京大学 ウイルスの精製方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140762A (en) * 1974-01-14 1979-02-20 Sandoz Ltd. Influenza sub-unit vaccine
US4240762A (en) * 1979-03-12 1980-12-23 Johnston Pump Company Seal-aligning rigid coupling assembly
SE8405493D0 (sv) * 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
KR101251902B1 (ko) * 2003-02-25 2013-04-08 메디뮨 엘엘씨 인플루엔자 백신 조성물의 제조 방법
RU2283139C1 (ru) * 2005-03-21 2006-09-10 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации Способ получения антигенов для вакцины против вирусов гриппа
EP1982727A1 (en) * 2007-04-17 2008-10-22 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for purification of viral proteins
RU2496519C2 (ru) * 2007-08-28 2013-10-27 Бакстер Интернэшнл Инк. Способ получения препарата, содержащего вирусные антигены, и применение препарата
EP2268309B1 (en) * 2008-03-18 2015-01-21 Novartis AG Improvements in preparation of influenza virus vaccine antigens
EP2344634A4 (en) * 2008-09-24 2012-08-29 Medimmune Llc METHODS OF CELL CULTURE, AND PROPAGATION AND PURIFICATION OF VIRUSES
CN102215865B (zh) * 2008-09-24 2013-10-30 米迪缪尼有限公司 病毒纯化方法
GB0918830D0 (en) * 2009-10-27 2009-12-09 Glaxosmithkline Biolog Niederl Process

Also Published As

Publication number Publication date
CA2841604C (en) 2020-01-21
RU2565827C2 (ru) 2015-10-20
BR112014001049A2 (pt) 2017-02-21
ES2653197T3 (es) 2018-02-06
CN103827296A (zh) 2014-05-28
EP2734619A1 (en) 2014-05-28
RU2014101484A (ru) 2015-07-27
KR20140038530A (ko) 2014-03-28
WO2013010797A1 (en) 2013-01-24
KR20160096215A (ko) 2016-08-12
AU2012286098A1 (en) 2014-01-23
EP2734619B1 (en) 2017-09-06
CA2841604A1 (en) 2013-01-24
JP6275641B2 (ja) 2018-02-07
TW201311896A (zh) 2013-03-16
AU2012286098C1 (en) 2016-09-15
CN103827296B (zh) 2016-11-16
JP2014524747A (ja) 2014-09-25

Similar Documents

Publication Publication Date Title
MX2014000753A (es) Procedimiento para producir antigeno viral y vacunas.
JOP20200091A1 (ar) جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري
MX2010003202A (es) Metodo para producir virus de la gripe.
EA201490583A1 (ru) Удаление примесных вирусов из препаратов аав
MD20140035A2 (ro) Metodă de tratament al hepatitei virale C
MX366422B (es) Proceso para preparar un producto lacteo fermentado colado.
MY161965A (en) New influenza virus immunizing epitope
WO2010148511A8 (en) Chimeric influenza virus-like particles comprising hemagglutinin
FR2967072B1 (fr) Procede pour ameliorer la production de virus et semences vaccinales influenza
EA033455B1 (ru) Кристаллические формы замещенных 5-фтор-1h-пиразолопиридинов, способы их получения, их применение для получения лекарственного средства, лекарственное средство и способ лечения на их основе
SG191166A1 (en) Virus like particle production in plants
HK1197414A1 (zh) 雌甾- -四烯- -甲酰胺衍生物、其製備方法、包含其的藥物製劑及其用於製備藥物的用途
EP2873423A3 (en) Soluble hiv-1 envelope glycoprotein trimers
MX2018006627A (es) Aumentar el rendimiento de particulas similares a virus en plantas.
MX2013013228A (es) Particulas similares a virus y proceso para prepararlas.
EA201400216A1 (ru) Консервирование биологических продуктов, в частности вакцин, с применением вакуума
EA201592298A1 (ru) Полуживая вирусная вакцина против респираторно-синцитиального вируса
FR2998579B1 (fr) Methode pour obtenir des anticorps humains specifiques d'un antigene par immunisation in vitro
MY183980A (en) Commercial scale process for production of prrsv
EP2484757A4 (en) VIRUS FOR THE EXPRESSION OF ALPHA GALACTOSE EPITOPES AND METHOD FOR THE PRODUCTION OF A VACCINE
IN2015DN02772A (es)
CU20150019A7 (es) Rotavirus humanos modificados
EA201592299A1 (ru) Полуживая вирусная вакцина против респираторно-синцитиального вируса
MY169503A (en) Preparation method of new recombinant antibacterial polypeptide medicine
WO2013055326A3 (en) Vaccines for human papilloma virus and methods for using the same

Legal Events

Date Code Title Description
FA Abandonment or withdrawal