CA2724322C - Diagnosis of melanoma and solar lentigo by nucleic acid analysis - Google Patents

Diagnosis of melanoma and solar lentigo by nucleic acid analysis Download PDF

Info

Publication number
CA2724322C
CA2724322C CA2724322A CA2724322A CA2724322C CA 2724322 C CA2724322 C CA 2724322C CA 2724322 A CA2724322 A CA 2724322A CA 2724322 A CA2724322 A CA 2724322A CA 2724322 C CA2724322 C CA 2724322C
Authority
CA
Canada
Prior art keywords
melanoma
skin
nucleic acid
protein
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2724322A
Other languages
English (en)
French (fr)
Other versions
CA2724322A1 (en
Inventor
Sherman H. Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dermtech Inc
Original Assignee
Dermtech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermtech Inc filed Critical Dermtech Inc
Publication of CA2724322A1 publication Critical patent/CA2724322A1/en
Application granted granted Critical
Publication of CA2724322C publication Critical patent/CA2724322C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Computing Systems (AREA)
  • Library & Information Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2724322A 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis Active CA2724322C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12773108P 2008-05-14 2008-05-14
US61/127,731 2008-05-14
US5398808P 2008-05-16 2008-05-16
US61/053,988 2008-05-16
US5814908P 2008-06-02 2008-06-02
US61/058,149 2008-06-02
PCT/US2009/044035 WO2009140550A2 (en) 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis

Publications (2)

Publication Number Publication Date
CA2724322A1 CA2724322A1 (en) 2009-11-19
CA2724322C true CA2724322C (en) 2019-07-16

Family

ID=41319348

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2724322A Active CA2724322C (en) 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis

Country Status (8)

Country Link
US (8) US20110160080A1 (enExample)
EP (2) EP2626437A3 (enExample)
JP (1) JP2011520451A (enExample)
CN (1) CN102089444A (enExample)
AU (1) AU2009246180B2 (enExample)
BR (1) BRPI0913578A2 (enExample)
CA (1) CA2724322C (enExample)
WO (1) WO2009140550A2 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008137465A1 (en) 2007-05-01 2008-11-13 The Regents Of The University Of California Methods for diagnosing ischemia
BRPI0811503A2 (pt) * 2007-05-04 2014-11-18 Dermtech Int Diagnótico de melanoma por análise de ácido nucleico
US20110160080A1 (en) 2008-05-14 2011-06-30 Chang Sherman H Diagnosis of Melanoma and Solar Lentigo by Nucleic Acid Analysis
WO2012009547A2 (en) 2010-07-14 2012-01-19 The Regents Of The University Of California Biomarkers for diagnosis of transient ischemic attacks
EP2593567B1 (en) 2010-07-15 2016-04-20 The Regents of The University of California Biomarkers for diagnosis of stroke and its causes
WO2012121978A2 (en) 2011-03-04 2012-09-13 The Regents Of The University Of California Biomarkers for the diagnosis of lacunar stroke
JP5841234B2 (ja) 2011-03-31 2016-01-13 ザ プロクター アンド ギャンブルカンパニー フケ/脂漏性皮膚炎の治療に有効な皮膚活性剤を特定及び評価するためのシステム、モデル、及び方法
CN103619317B (zh) * 2011-04-22 2017-06-09 欧莱雅 和细胞外基质结构相关的皮肤色斑分子标签
FR2974371B1 (fr) * 2011-04-22 2016-10-28 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la famille des proteoglycanes et glycoproteines extracellulaires
EP2699221B1 (fr) * 2011-04-22 2017-02-08 L'Oréal Signature moléculaire des taches pigmentaires cutanées, associée à la matrice extracellulaire
FR2974370B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la voie de signalisation tgf-beta - smad
FR2974373B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la matrice extracellulaire
FR2974372B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee au remodelage de la matrice extracellulaire
US9410204B2 (en) 2012-01-07 2016-08-09 The Regents Of The University Of California Biomarkers for diagnosing ischemia
US10468120B2 (en) * 2012-03-30 2019-11-05 The Procter & Gamble Company Method of generating a hyperpigmentation condition gene expression signature
MX2014014898A (es) 2012-06-06 2015-03-04 Procter & Gamble Sistemas y metodos de identificacion de agentes cosmeticos para composiciones para el cuidado del cabello/cuero cabelludo.
JP6366580B2 (ja) * 2012-06-22 2018-08-01 エイチティージー モレキュラー ダイアグノスティクス, インコーポレイテッド メラニン細胞性病変における分子悪性度
KR102017562B1 (ko) * 2013-03-13 2019-09-03 (주)아모레퍼시픽 미백 효능 물질의 스크리닝 방법
US11021752B2 (en) 2013-03-15 2021-06-01 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
US20150005184A1 (en) * 2013-06-28 2015-01-01 Dermtech International Diagnosis of melanoma by nucleic acid analysis
FR3015524B1 (fr) * 2013-12-20 2016-06-03 Oreal Signature moleculaire du lentigo actinique specifique des peaux asiatiques
FR3015526B1 (fr) * 2013-12-20 2017-02-17 Oreal Biomarqueur npy1r du lentigo actinique
FR3015523B1 (fr) * 2013-12-20 2020-05-29 L'oreal Signature moleculaire du lentigo actinique
FR3015525B1 (fr) * 2013-12-20 2017-06-09 Oreal Biomarqueur rnase 7 du lentigo actinique
WO2016179043A1 (en) 2015-05-01 2016-11-10 Dermtech, Inc. Non-invasive skin collection system
EP3164508B1 (en) 2014-07-02 2023-06-07 Myriad myPath, LLC Genes and gene signatures for diagnosis and treatment of melanoma
JPWO2016152352A1 (ja) * 2015-03-20 2018-01-11 国立大学法人名古屋大学 メラノーマ特異的バイオマーカー及びその利用
US20190086392A1 (en) * 2016-03-21 2019-03-21 Inserm (Institut National De La Sante Et De La Recherch Medicale) Methods for diagnosis and treatment of solar lentigo
JP6231252B1 (ja) 2016-07-08 2017-11-15 花王株式会社 核酸試料の調製方法
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
JP7431812B2 (ja) 2018-05-09 2024-02-15 ダームテック,インク. 自己免疫疾患における新規な遺伝子分類とその使用
CA3134936A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CA3136108A1 (en) * 2019-04-05 2020-10-08 Dermtech, Inc. Novel gene classifiers for use in monitoring uv damage
EP3883149B1 (en) * 2020-03-20 2026-05-27 Volkswagen Ag Method, apparatus and computer program for predicting a future quality of service of a wireless communication link
EP4194565A4 (en) * 2020-08-10 2024-05-22 Cutis Biomedical Research Center Minimally invasive kit for diagnosing skin condition, comprising microneedle patch
EP4251773A4 (en) * 2020-11-24 2024-10-30 Dermtech, Inc. Assessment of mutation burden in skin
USD966300S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD966299S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD989861S1 (en) 2021-02-16 2023-06-20 Dermtech, Inc. Dermatology report document
USD988399S1 (en) 2021-02-16 2023-06-06 Dermtech, Inc. Dermatology report document
US20240191309A1 (en) * 2021-04-13 2024-06-13 Dermtech, Inc. Gene classifiers and uses thereof
WO2023015286A1 (en) * 2021-08-05 2023-02-09 The Regents Of The University Of California Gene/protein expression guided melanoma surgery
GB202112817D0 (en) * 2021-09-08 2021-10-20 Mitra Bio Ltd Methods, compositions, and kits for characterizing skins
FR3135992A1 (fr) * 2022-05-25 2023-12-01 L'oreal Signature moléculaire du lentigo actinique associée à la gestion des vésicules
USD1061554S1 (en) 2022-09-09 2025-02-11 Dermtech, Llc Computer display panel with a graphical user interface for a dermatology report
GB202302959D0 (en) 2023-02-28 2023-04-12 Mitra Bio Ltd A method for determining a stage of an epigenetic property of an epidermis
WO2024192031A1 (en) * 2023-03-12 2024-09-19 Novelna Inc. Melanoma detection proteins and methods of use thereof

Family Cites Families (254)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441430A (en) 1964-11-19 1969-04-29 Minnesota Mining & Mfg Adhesives and adhesive tapes
US4122947A (en) 1978-01-27 1978-10-31 Falla Marjorie B Pre-packaged patient identification kit
JPS567007A (en) 1979-06-29 1981-01-24 Toshiba Corp Coating film thickness measuring apparatus
GB2061598B (en) 1979-10-15 1983-03-02 Chloride Silent Power Ltd Filling sodium-sulphur cells
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
JPS57156456A (en) 1981-03-24 1982-09-27 Shizuoka Daigaku Preparation of 1,5,5-trimethyl-3-amino-4-cyanocyclohexa-1,3- diene and its derivative
US4388432A (en) 1981-12-15 1983-06-14 Permacel Repulpable acrylic acid based pressure-sensitive adhesive
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
SE443914B (sv) 1984-10-01 1986-03-17 Torkel Ingemar Fischer Medel for en overkenslighetstest
US4851510A (en) 1984-11-30 1989-07-25 Wadley Technologies, Inc. Monoclonal antibodies to novel melanoma-associated antigens
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4777964A (en) 1986-01-02 1988-10-18 David Briggs System for obtaining blood samples and submitting for testing of aids
US5460939A (en) 1986-04-18 1995-10-24 Advanced Tissue Sciences, Inc. Temporary living skin replacement
US4971800A (en) 1988-07-08 1990-11-20 The Regents Of The University Of California Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents
US5493009A (en) 1989-11-14 1996-02-20 New York Medical College Antiidiotypic monoclonal antibodies MK2-23 anti-melanomal antibody 763.74
ATE142273T1 (de) 1990-06-08 1996-09-15 Behringwerke Ag Verfahren zur quantitativen bestimmung von dns- sequenzen
US6033854A (en) 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5583032A (en) 1992-10-21 1996-12-10 The Cleveland Clinic Foundation And National Institutes Of Health Method of cleaving specific strands of RNA
US5753612A (en) 1992-10-27 1998-05-19 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists
US5654286A (en) 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
AU7324994A (en) 1993-07-08 1995-02-06 Avery Dennison Corporation Acrylic-saturated rubber hybrid pressure-sensitive adhesives
WO1995006137A1 (en) 1993-08-27 1995-03-02 Australian Red Cross Society Detection of genes
US5843657A (en) 1994-03-01 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Isolation of cellular material under microscopic visualization
US5989815A (en) 1994-03-18 1999-11-23 University Of Utah Research Foundation Methods for detecting predisposition to cancer at the MTS gene
US5962477A (en) 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
JPH0852142A (ja) 1994-07-01 1996-02-27 Medical Biopsy Inc 試料保持手段を備えた生検針組立体及びその使用方法
IT1278052B1 (it) 1995-03-14 1997-11-17 Mendes Srl Uso delle immunoglobuline della classe g, in particolare delle immunoglobuline per uso endovenoso o per uso intramuscolare, per
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6312909B1 (en) 1996-03-29 2001-11-06 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis prevention and treatment of tumor progression
US6054277A (en) 1996-05-08 2000-04-25 Regents Of The University Of Minnesota Integrated microchip genetic testing system
US5811239A (en) 1996-05-13 1998-09-22 Frayne Consultants Method for single base-pair DNA sequence variation detection
AU730633B2 (en) 1996-05-29 2001-03-08 Phillip Belgrader Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5858683A (en) 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
US5921396A (en) 1997-01-21 1999-07-13 Brown, Jr.; Jacob T. Specimen collection kit for mailing and method of using same
US6056859A (en) 1997-02-12 2000-05-02 Lockheed Martin Energy Research Corporation Method and apparatus for staining immobilized nucleic acids
DE19733014A1 (de) 1997-07-31 1999-02-04 Beiersdorf Ag Selbstklebeband
US6551799B2 (en) 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20020006913A1 (en) 1997-11-04 2002-01-17 Von Borstel Reid W. Antimutagenic compositions for treatment and prevention of photodamage to skin
US6054276A (en) 1998-02-23 2000-04-25 Macevicz; Stephen C. DNA restriction site mapping
US6106732A (en) 1998-04-16 2000-08-22 Binax Services, Inc. Integral blood plasma or serum isolation, metering and transport device
US6891022B1 (en) 1998-04-23 2005-05-10 Genentech, Inc. NSP molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
JP3813818B2 (ja) 1998-05-01 2006-08-23 アリゾナ ボード オブ リージェンツ オリゴヌクレオチドおよびdna分子のヌクレオチド配列の決定方法
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
IL141481A0 (en) 1998-08-18 2002-03-10 Dermtech Int Method for detection of biological factors in epidermis
KR100326937B1 (ko) 1998-09-23 2002-03-13 정연보 접착성 쉬트로 사람의 표피 dna 샘플을 획득하는 방법
US6176836B1 (en) 1998-09-25 2001-01-23 David Trudil Biological sample collection kit
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
US7700324B1 (en) 1998-11-03 2010-04-20 The Johns Hopkins University School Of Medicine Methylated CpG island amplification (MCA)
WO2000040749A2 (en) 1999-01-06 2000-07-13 Genenews Inc. Method for the detection of gene transcripts in blood and uses thereof
US7094533B1 (en) 1999-01-21 2006-08-22 Board Of Regents Of The University Of Nebraska Therapeutic and diagnostic applications of prostatic acid phosphatase in prostate cancer
US6274362B1 (en) 1999-02-04 2001-08-14 Millennium Pharmaceuticals, Inc. RGS-containing molecules and uses thereof
US6982089B2 (en) 1999-02-24 2006-01-03 Tact Ip, Llc Cytokine antagonists for neurological and neuropsychiatric disorders
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
US6180349B1 (en) 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
US6569624B1 (en) 1999-08-12 2003-05-27 Wisconsin Alumni Research Foundation Identification of genetic markers of biological age and metabolism
AUPQ265899A0 (en) 1999-09-03 1999-09-30 Genetic Solutions Pty Ltd Sampling system
AU7987800A (en) 1999-09-29 2001-04-30 Lifespan Biosciences, Inc. Anti-aging nucleic acid and protein targets
US6447463B1 (en) 1999-11-10 2002-09-10 Piotr Borkowski Highly sensitive, practical, widely available diagnostic kit for fungal skin infections
US6726971B1 (en) 1999-12-13 2004-04-27 Tyco Adhesives Lp Thermally stable clear polyurethane adhesive tape
IL133976A (en) 2000-01-11 2006-09-05 Dermipsor Ltd Agents for the treatment of skin disorders
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
JP2001228449A (ja) * 2000-02-14 2001-08-24 Hamamatsu Photonics Kk レーザ集光装置及びレーザ加工装置
AU2001259710A1 (en) 2000-05-09 2001-11-20 Genetics Institute, Llc Compositions, kits, and methods for identification, assessment, prevention, and therapy of psoriasis
EP1176200A3 (de) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
US7105292B2 (en) 2000-09-08 2006-09-12 New York University Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure
US20020165192A1 (en) 2000-09-19 2002-11-07 Kerr William G. Control of NK cell function and survival by modulation of ship activity
US20030017573A1 (en) * 2000-10-04 2003-01-23 Board Of Regents, The University Of Texas System Polymerase kappa compositions and methods thereof
DE10100121A1 (de) 2001-01-03 2002-08-01 Henkel Kgaa Verfahren zur Bestimmung des Hautstreß oder der Hautalterung in vitro
US20020132274A1 (en) 2001-01-17 2002-09-19 Nevalainen Marja T. Diagnostic and monitorings methods for cancer
US20030044406A1 (en) 2001-03-02 2003-03-06 Christine Dingivan Methods of preventing or treating inflammatory or autoimmune disorders by administering CD2 antagonists in combination with other prophylactic or therapeutic agents
US6642298B2 (en) 2001-03-16 2003-11-04 National Starch And Chemical Investment Holding Corporation Rubber-acrylic adhesive formulation
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
DE10130800B4 (de) 2001-06-22 2005-06-23 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierung mit hoher Sensitivität
US7297480B2 (en) 2001-06-28 2007-11-20 Dermtech International Method for detection of melanoma
US6749792B2 (en) 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
JP2003029201A (ja) 2001-07-11 2003-01-29 Canon Inc 画像投射装置及び画像補正方法
WO2003006058A1 (en) 2001-07-12 2003-01-23 Wyeth Cd25+ differential markers and uses thereof
US7229774B2 (en) * 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US7247426B2 (en) * 2001-08-02 2007-07-24 Agilent Technologies, Inc. Classifying cancers
US6857262B2 (en) 2001-08-16 2005-02-22 Spx Corporation Catalytic converter function detection
WO2003032259A1 (en) * 2001-09-27 2003-04-17 Fujitsu Limited Efficient download of content data through network
CN1612936A (zh) 2001-11-09 2005-05-04 苏尔斯精细医药公司 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
US6692032B2 (en) * 2001-11-28 2004-02-17 Melanie Ann Christy Mole monitoring system
US20030113906A1 (en) 2001-12-14 2003-06-19 Sangha Jangbir S. Method and apparatus for DNA collection
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
US20090082265A1 (en) 2002-01-04 2009-03-26 Myriad Genetics, Incorporated Compositions and methods for treating diseases
US7396871B2 (en) 2002-01-14 2008-07-08 Eastman Chemical Comapny Rubber modified acrylic and/or vinyl hybrid resins
AU2003212878A1 (en) 2002-01-30 2003-09-02 Epigenomics Ag Identification of cell differentiation states based on methylation patterns
US20030167556A1 (en) 2002-03-05 2003-09-11 Consumers Choice Systems, Inc. Methods and devices for transdermal delivery of anti-aging compounds for treatment and prevention of facial or neck skin aging
US20030224422A1 (en) 2002-04-08 2003-12-04 St. Jude Children's Research Hospital, Inc. Pre-and post therapy gene expression profiling to identify drug targets
CA2485968A1 (en) 2002-05-16 2004-06-03 Vanderbilt University Method for predicting autoimmune diseases
US7217853B2 (en) 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
US7267951B2 (en) 2002-06-05 2007-09-11 Sloan-Kettering Institute For Cancer Research Method for evaluating a tissue or biopsy sample to determine if the sample is early-stage melanoma
JP4384603B2 (ja) 2002-06-26 2009-12-16 コールド スプリング ハーバー ラボラトリー メチル化プロファイルを測定するための方法および組成物
US20080260744A1 (en) 2002-09-09 2008-10-23 Omeros Corporation G protein coupled receptors and uses thereof
JP2006518582A (ja) 2002-09-11 2006-08-17 ジェネンテック・インコーポレーテッド 乾癬の治療のための新規組成物と方法
EP1572116A4 (en) 2002-11-26 2007-12-12 Genentech Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE DISEASES
US20070077553A1 (en) 2003-10-30 2007-04-05 Rosetta Genomics Bioinformatically detectable group of novel vaccinia regulatory genes and uses thereof
US20040191782A1 (en) 2003-03-31 2004-09-30 Yixin Wang Colorectal cancer prognostics
WO2004105573A2 (en) 2003-05-21 2004-12-09 The Wistar Institute Of Anatomy And Biology Method of diagnosis of cancer based on gene expression profiles in cells
US20060019256A1 (en) 2003-06-09 2006-01-26 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
WO2005012578A1 (en) 2003-07-31 2005-02-10 Sequenom, Inc. Methods for high level multiplexed polymerase chain reactions and homogeneous mass extension reactions for genotyping of polymorphisms
EP1510577A1 (en) 2003-08-29 2005-03-02 Qiagen GmbH Method for magnetic bead isolation of nucleic acids
IL157786A (en) 2003-09-07 2010-11-30 Ahava Dead Sea Lab Ltd Personalized cosmetics
EP1689887B1 (en) 2003-10-21 2012-03-21 Orion Genomics, LLC Methods for quantitative determination of methylation density in a dna locus
EP1676116B8 (de) 2003-10-21 2012-07-04 Leica Microsystems CMS GmbH Verfahren zur automatischen erzeugung von laser-schnittlinien in der laser-mikrodissektion
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
EP1557449A1 (en) 2004-01-22 2005-07-27 3M Innovative Properties Company Adhesive tape for structural bonding
US20050261210A1 (en) 2004-02-19 2005-11-24 Bhatnagar Rajiv S Nonsense suppressor agents in treatment of cutaneous and gastrointestinal disorders
WO2005091777A2 (en) 2004-02-27 2005-10-06 Nuvelo, Inc. Methods and materials relating to insulin growth factor-like (igfl) polypeptides and polynucleotides
WO2005085477A1 (en) 2004-03-02 2005-09-15 Orion Genomics Llc Differential enzymatic fragmentation by whole genome amplification
JP4526839B2 (ja) 2004-03-05 2010-08-18 株式会社資生堂 角層中の酸化タンパク質を指標とする角層の透明性・保水性を評価する方法
US7183057B2 (en) 2004-03-31 2007-02-27 Dermtech International Tape stripping methods for analysis of skin disease and pathological skin state
US20050287593A1 (en) 2004-05-03 2005-12-29 Schering Corporation Use of cytokine expression to predict skin inflammation; methods of treatment
AU2005241020B2 (en) 2004-05-03 2008-07-10 Merck Sharp & Dohme Corp. Use of IL-17 expression to predict skin inflammation; methods of treatment
JP4790231B2 (ja) 2004-06-17 2011-10-12 花王株式会社 表皮の解析方法
ATE488766T1 (de) * 2004-06-21 2010-12-15 Progenra Inc Diagnostik und screening-methode und kit in verbindung mit proteolytischer aktivität
MX2007000291A (es) * 2004-06-25 2007-08-07 Johnson & Johnson Metodos y reactivos para la deteccion de melanoma.
US20070154889A1 (en) * 2004-06-25 2007-07-05 Veridex, Llc Methods and reagents for the detection of melanoma
US7635563B2 (en) 2004-06-30 2009-12-22 Massachusetts Institute Of Technology High throughput methods relating to microRNA expression analysis
US20080032293A1 (en) 2004-07-15 2008-02-07 The University Of North Carolina At Chapel Hill Housekeeping Genes And Methods For Identifying Same
WO2006039399A2 (en) * 2004-09-29 2006-04-13 University Of Rochester Staufen 1 (stau1) - mediated mrna decay
AU2005297303B2 (en) 2004-10-19 2011-11-10 Lsip, Llc Novel diagnostic kit for malignant melanoma
US7643818B2 (en) 2004-11-22 2010-01-05 Seven Networks, Inc. E-mail messaging to/from a mobile terminal
EP1817430B1 (en) 2004-11-29 2009-09-16 Klinikum der Universität Regensburg Means and methods for detecting methylated dna
KR101286833B1 (ko) 2005-03-18 2013-07-17 가부시키가이샤 시세이도 편평상피세포암 관련 항원을 지표로 하는 피부 성상의 평가방법
CA2603780A1 (en) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics, Inc. Sema4d in cancer diagnosis, detection and treatment
WO2006113671A2 (en) 2005-04-15 2006-10-26 Oncomethylome Sciences, S.A. Methylation markers for diagnosis and treatment of cancers
WO2006128192A2 (en) 2005-05-27 2006-11-30 John Wayne Cancer Institute Use of free circulating dna for diagnosis, prognosis, and treatment of cancer
US20070082347A1 (en) 2005-06-08 2007-04-12 Myriad Genetics, Incorporated Gene variants and use thereof
US20070099209A1 (en) 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
JP2007050126A (ja) 2005-08-18 2007-03-01 Dr Ito Procare Cosmetics:Kk 美容方法
US7972788B2 (en) 2005-08-23 2011-07-05 Fancl Corporation Skin aging marker and technique for use thereof
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
US20070243537A1 (en) 2006-04-14 2007-10-18 Tuck Edward F Human sample matching system
CN103278641A (zh) 2005-10-21 2013-09-04 株式会社芳珂 特应性皮炎标记物及其利用技术
CA2630974A1 (en) 2005-11-23 2007-05-31 University Of Utah Research Foundation Methods and compositions involving intrinsic genes
WO2007077257A2 (en) 2006-01-05 2007-07-12 Galderma Research & Development Acne lesions biomarkers and modulators thereof
JP5027528B2 (ja) 2006-03-02 2012-09-19 株式会社ファンケル 皮膚老化の検査方法
WO2007124072A2 (en) 2006-04-20 2007-11-01 Dermtech International Methods for capture and detection of micro-rna molecules from the skin by non-invasive tape stripping
CN101473045B (zh) 2006-04-24 2016-08-03 健泰科生物技术公司 用于检测自身免疫性病症的方法和组合物
CN101472611A (zh) 2006-06-19 2009-07-01 惠氏公司 调节il-22和il-17的方法
US20090317840A1 (en) 2006-07-27 2009-12-24 Heinrichs Jon H Automated determination of chlamydia infection-forming units
WO2008030986A2 (en) 2006-09-06 2008-03-13 The Regents Of The University Of California Molecular diagnosis and classification of malignant melanoma
WO2008031041A2 (en) 2006-09-07 2008-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
US20080070883A1 (en) 2006-09-19 2008-03-20 Wyeth Use of LXR modulators for the prevention and treatment of skin aging
EP2069377A4 (en) 2006-09-27 2009-11-11 Univ California METHOD AND COMPOSITIONS FOR THE TREATMENT OF SKIN DISEASES AND SKIN FUNCTIONAL DISORDERS
EP2102367A2 (en) 2006-11-09 2009-09-23 XDX, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
GB0700374D0 (en) 2007-01-09 2007-02-14 Oncomethylome Sciences S A NDRG family methylation markers
EP2125659B1 (en) 2007-02-01 2016-01-13 Siemens Healthcare Diagnostics Inc. Silica magnetic particles with a high nucleic acid binding capability
BRPI0811503A2 (pt) 2007-05-04 2014-11-18 Dermtech Int Diagnótico de melanoma por análise de ácido nucleico
US8911937B2 (en) 2007-07-19 2014-12-16 Brainreader Aps Method for detecting methylation status by using methylation-independent primers
WO2009014766A2 (en) 2007-07-26 2009-01-29 The University Of Utah Research Foundation Non-invasive recovery of rna and analysis of gene expression in skin
EP2184997A4 (en) 2007-07-31 2010-11-03 Univ New York DIAGNOSIS AND TREATMENT METHODS FOR THE CHARACTERIZATION OF BACTERIAL MICROORGANISMS IN SKIN DISEASES
WO2009021141A1 (en) 2007-08-07 2009-02-12 The Johns Hopkins University Comprehensive high throughput arrays for relative methylation
US20090047309A1 (en) 2007-08-13 2009-02-19 Maes Daniel H Cosmetic methods and compositions for repairing human skin
US7965820B2 (en) 2007-08-17 2011-06-21 Brookhaven Science Associates, Llc Fiducial marker for correlating images
KR100999261B1 (ko) 2007-10-09 2010-12-07 (주)아모레퍼시픽 여성호르몬 결핍으로 초래되는 여성 피부의 노화 억제제 스크리닝 방법
EP2053131A1 (en) 2007-10-19 2009-04-29 Ludwig-Maximilians-Universität München Method for determining methylation at deoxycytosine residues
WO2009053493A1 (en) 2007-10-26 2009-04-30 Galderma Research & Development Non-invasive method to perform skin inflammatory disease pharmaco-genomic studies and diagnosis method thereof
US20090246768A1 (en) 2008-02-15 2009-10-01 Sawalha Amr H Predicting and Diagnosing Patients With Autoimmune Disease
ES2489840T3 (es) 2008-03-05 2014-09-02 The Regents Of The University Of California Pronóstico molecular y clasificación de melanoma maligno en base a marcadores seleccionados entre la lista que consiste en RGS1, NCOA3, SPP1, PHIP
WO2009123373A1 (en) 2008-04-04 2009-10-08 Goodgene Inc. New skin sampling kit which stores nucleic acids in stable status, genetic test methods by using the kit and their practical application
WO2009131733A1 (en) 2008-04-21 2009-10-29 The Trustees Of Columbia University In The City Of New York Gab2 amplification in melanoma
US20110160080A1 (en) 2008-05-14 2011-06-30 Chang Sherman H Diagnosis of Melanoma and Solar Lentigo by Nucleic Acid Analysis
JP5568807B2 (ja) 2008-06-06 2014-08-13 静岡県 プロテオミクス解析を用いたメラノーママーカーの同定
CA2728490A1 (en) 2008-06-17 2009-12-23 University Of Rochester Tumor suppression through plexin c1
EP2151505A1 (en) 2008-08-05 2010-02-10 Institut Gustave Roussy Method for determining a predisposition to basal cell carcinoma and for screening treatments thereof
EP2977469A1 (en) 2008-08-28 2016-01-27 Dermtech International Determining age ranges of skin samples
CA2737106A1 (en) 2008-10-03 2010-04-08 Dana-Farber Cancer Institute, Inc. Compositions, kits and methods for the diagnosis, prognosis, and monitoring of cancer using golph3
WO2010048431A2 (en) 2008-10-22 2010-04-29 Reveal Sciences, Llc Device, method and apparatus for analysing skin and hair
ES2796111T3 (es) 2008-11-14 2020-11-25 Brigham & Womens Hospital Inc Métodos terapéuticos relacionados con células madre cancerosas
EP3831954A3 (en) 2008-11-17 2021-10-13 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
HU0900117D0 (en) 2009-02-26 2009-04-28 Genetic Immunity Kutatasi Topical or transdermal delivery kit
US20130143747A1 (en) 2011-12-05 2013-06-06 Myriad Genetics, Incorporated Methods of detecting cancer
US20110040571A1 (en) 2009-08-14 2011-02-17 Felicity Warren System and method for providing for teledermatology
WO2011039734A2 (en) 2009-10-02 2011-04-07 Enzo Medico Use of genes involved in anchorage independence for the optimization of diagnosis and treatment of human cancer
CN102667484A (zh) 2009-10-13 2012-09-12 约翰·霍普金斯大学 识别黑素瘤肿瘤细胞的生物标记
GB0921329D0 (en) 2009-12-04 2010-01-20 Univ Surrey Biomarker
US20130079423A1 (en) 2010-02-24 2013-03-28 Myriad Genetics, Incorporated Diagnostic methods involving loss of heterozygosity
WO2011109224A1 (en) 2010-03-01 2011-09-09 The United States Of America, As Represented By The Secretary,Department Of Health & Human Services Gene sets for detection ultraviolet a exposure and methods of use thereof
AU2011242990B2 (en) 2010-04-19 2015-02-12 Biomarker Strategies, Llc. Compositions and methods for prediction of drug sensitivity, resistance, and disease progression
GB201012590D0 (en) 2010-07-27 2010-09-08 Queen Mary & Westfield College Methods for diagnosing cancer
EP2611941A4 (en) 2010-08-30 2014-01-22 Myriad Genetics Inc GENESIS OF CANCER DIAGNOSIS AND PROGNOSIS
WO2012031008A2 (en) 2010-08-31 2012-03-08 The General Hospital Corporation Cancer-related biological materials in microvesicles
US20130237445A1 (en) 2010-09-14 2013-09-12 The University Of North Carolina At Chapel Hill Methods and kits for detecting melanoma
US20120071343A1 (en) 2010-09-20 2012-03-22 Advanced Cell Diagnostics, Inc Biomarkers for differentiating melanoma from benign nevus in the skin
US20120201750A1 (en) 2010-09-20 2012-08-09 Bungwoo Ryu Serum biomarkers for melanoma metastasis
JP2014507160A (ja) 2011-02-22 2014-03-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス.アー.エール.エル. 循環バイオマーカー
WO2012125411A1 (en) 2011-03-11 2012-09-20 Metamark Genetics, Inc. Methods of predicting prognosis in cancer
EP2721179A4 (en) 2011-06-16 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L BIOMARKER COMPOSITIONS AND METHOD THEREFOR
JP5965481B2 (ja) 2011-07-15 2016-08-03 レオ ファーマ アクティーゼルスカブ 皮膚t細胞リンパ腫(ctcl)の診断用マイクロrnaプロファイリング
CN103874770A (zh) 2011-08-08 2014-06-18 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
AU2012301664A1 (en) 2011-08-31 2014-02-27 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of cancer
AU2012312170C1 (en) 2011-09-21 2018-01-04 Shiseido Company, Ltd. Compositions and methods for treating conditions of compromised skin barrier function
WO2013041724A1 (en) 2011-09-23 2013-03-28 Galderma Research & Development Human keratinocytes ptch1 cell line
CN103987861A (zh) 2011-10-14 2014-08-13 加州大学评议会 皮肤鳞状细胞癌和假性上皮瘤样增生的基于多重pcr的测试及其区分方法
EP2768859B1 (en) 2011-10-19 2018-02-21 MorphoSys AG Antagonists of il17c for the treatment of inflammatory disorders
IN2014CN04935A (enExample) 2011-12-31 2015-09-18 Moni Abraham Kuriakose
KR101794396B1 (ko) 2012-05-02 2017-11-06 미쯔비시 케미컬 주식회사 피부에 대한 자외선의 영향을 평가하기 위한 프로브 또는 프로브 세트 및 핵산 마이크로 어레이
WO2013184905A1 (en) 2012-06-06 2013-12-12 Myriad Genetics, Inc. Hereditary cancer genes
WO2014028461A2 (en) 2012-08-13 2014-02-20 The Rockefeller University Treatment and diagnosis of melanoma
ES3015226T3 (en) 2012-08-16 2025-04-30 Veracyte Sd Inc Prostate cancer prognosis using biomarkers
US9103749B2 (en) 2012-10-11 2015-08-11 Fast Forward Forensics, LLC Biological sample collection apparatus
US20160051493A1 (en) 2012-11-19 2016-02-25 The Trustees Of Columbia University In The City Of New York Methods of treatment of keratinocyte-derived lesions
TWI493169B (zh) 2013-01-18 2015-07-21 Univ Nat Cheng Kung 評估皮膚生理參數濃度及分布之光學系統及其方法
JP6574385B2 (ja) 2013-02-18 2019-09-11 デューク ユニバーシティー 神経膠腫および腫瘍のサブセットにおけるtertプロモーター変異
WO2014130507A1 (en) 2013-02-22 2014-08-28 Avery Dennison Corporation Multi-layer optically clear adhesives, foams, transfer tapes, and articles comprising such adhesives
US20140323331A1 (en) 2013-04-26 2014-10-30 Dermtech International Biomarkers for diagnosis and treatment of acne vulgaris
TW201537175A (zh) 2013-06-28 2015-10-01 Chugai Pharmaceutical Co Ltd 預測罹患具皮膚搔癢之疾病的患者對il-31拮抗劑之治療的反應之方法
US20150005184A1 (en) 2013-06-28 2015-01-01 Dermtech International Diagnosis of melanoma by nucleic acid analysis
US20150377751A1 (en) 2013-08-01 2015-12-31 The Procter & Gamble Company Method of collecting and quantifying melanin in skin
FR3011009B1 (fr) 2013-09-25 2016-11-25 Oreal Signature bacterienne de la dermatite atopique et son utilisation dans la prevention et/ou le traitement de cette pathologie
WO2015093998A1 (en) 2013-12-19 2015-06-25 Instytut Biologii Doświadczalnej Im. M. Nenckiego Polskiej Akademii Nauk A method for detecting an increased risk of developing skin cancer and a use of a genotype variant of the grhl3 gene
WO2016179043A1 (en) 2015-05-01 2016-11-10 Dermtech, Inc. Non-invasive skin collection system
WO2015184061A2 (en) 2014-05-28 2015-12-03 Dana-Farber Cancer Institute, Inc. Activating jak kinase biomarkers predictive of anti-immune checkpoint inhibitor response
WO2015191783A2 (en) 2014-06-10 2015-12-17 Abbvie Inc. Biomarkers for inflammatory disease and methods of using same
US20160024595A1 (en) 2014-07-22 2016-01-28 Dermtech International Characterization of melanoma using a molecular signature
WO2016030287A1 (de) 2014-08-27 2016-03-03 Heraeus Deutschland GmbH & Co. KG Verfahren zur herstellung einer lötverbindung
WO2017083576A1 (en) 2015-11-10 2017-05-18 Pathway Genomics Corporation Methods and systems for improving skin condition
US10852307B2 (en) 2015-12-22 2020-12-01 National Jewish Health Methods of detecting and preventing atopic allergic diseases
WO2017151524A1 (en) 2016-02-29 2017-09-08 Foundation Medicine, Inc. Methods and systems for evaluating tumor mutational burden
US11613784B2 (en) 2016-03-25 2023-03-28 The Trustees Of Columbia University In The City Of New York Next-generation biomarkers to detect sun damage and predict skin cancer risk
WO2017197143A2 (en) 2016-05-11 2017-11-16 Sensus Healthcare Llc Virtual pathology for dermatology
CN106119242A (zh) 2016-06-24 2016-11-16 毕建红 一种基于自动化工作站的疑难微量法医物证dna提取试剂盒及其方法
WO2018011628A1 (en) 2016-07-11 2018-01-18 Lifesci Pharmaceuticals, Inc. Therapeutic inhibitory compounds
WO2018065384A1 (en) 2016-10-03 2018-04-12 Galderma Research & Development Expression profiles of abc and slc transporters in human and minipig skin, liver and kidney
CN110140040A (zh) 2016-11-09 2019-08-16 豪夫迈·罗氏有限公司 自动化的组织切割仪器及其使用方法
WO2018093724A1 (en) 2016-11-15 2018-05-24 Quest Diagnostics Investments Llc Methods for detecting dna mutations using mitra tip extraction
FR3060755B1 (fr) 2016-12-16 2024-07-12 Oreal Methode de diagnostic d'une peau presentant des signes de secheresse
US11911012B2 (en) 2017-03-03 2024-02-27 Children's Hospital Medical Center Non-invasive methods for skin sample collection and analysis
CA3059425A1 (en) 2017-04-10 2018-10-18 Dermtech, Inc. Non-invasive skin-based detection methods
WO2019005764A1 (en) 2017-06-27 2019-01-03 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center MHC-I GENOTYPE LIMITING THE ONCOGEN MUTATIONAL LANDSCAPE
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
JP7431812B2 (ja) 2018-05-09 2024-02-15 ダームテック,インク. 自己免疫疾患における新規な遺伝子分類とその使用
WO2019236632A1 (en) 2018-06-04 2019-12-12 Avon Products. Inc. Protein biomarkers for identifying and treating aging skin and skin conditions
GB201810897D0 (en) 2018-07-03 2018-08-15 Chronomics Ltd Phenotype prediction
GB2576374A (en) 2018-08-17 2020-02-19 Ecole Polytechnique Fed Lausanne Epfl Skin cell analysis
CN109785903A (zh) 2018-12-29 2019-05-21 哈尔滨工业大学(深圳) 一种基因表达数据分类器
CA3134936A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CA3136108A1 (en) 2019-04-05 2020-10-08 Dermtech, Inc. Novel gene classifiers for use in monitoring uv damage
EP4138677A4 (en) 2020-04-22 2024-08-07 Dermtech, Inc. Teledermatology system and methods
JP2023525031A (ja) 2020-05-08 2023-06-14 ダームテック,インク. 自動化されたサンプル走査および分離のシステムと方法
EP4251773A4 (en) 2020-11-24 2024-10-30 Dermtech, Inc. Assessment of mutation burden in skin
US20240167102A1 (en) 2021-03-02 2024-05-23 Dermtech, Inc. Predicting therapeutic response
US20240191309A1 (en) 2021-04-13 2024-06-13 Dermtech, Inc. Gene classifiers and uses thereof
AU2022286437A1 (en) 2021-06-04 2023-12-21 Dermtech, Llc Sample collection system

Also Published As

Publication number Publication date
US20150361509A1 (en) 2015-12-17
CA2724322A1 (en) 2009-11-19
US11753687B2 (en) 2023-09-12
AU2009246180A1 (en) 2009-11-19
US20210222258A1 (en) 2021-07-22
US20140154684A1 (en) 2014-06-05
US20110160080A1 (en) 2011-06-30
EP2294216A2 (en) 2011-03-16
EP2626437A3 (en) 2013-12-11
WO2009140550A9 (en) 2010-01-07
US20190367994A1 (en) 2019-12-05
US20140256584A1 (en) 2014-09-11
US9057109B2 (en) 2015-06-16
BRPI0913578A2 (pt) 2017-06-06
JP2011520451A (ja) 2011-07-21
US11332795B2 (en) 2022-05-17
US20210246514A1 (en) 2021-08-12
CN102089444A (zh) 2011-06-08
EP2626437A2 (en) 2013-08-14
EP2294216A4 (en) 2011-11-23
US20210198749A1 (en) 2021-07-01
WO2009140550A3 (en) 2010-02-25
AU2009246180B2 (en) 2015-11-05
US10407729B2 (en) 2019-09-10
WO2009140550A2 (en) 2009-11-19

Similar Documents

Publication Publication Date Title
US11753687B2 (en) Diagnosis of melanoma and solar lentigo by nucleic acid analysis
US20080274908A1 (en) Diagnosis of melanoma by nucleic acid analysis
Prueitt et al. Expression of microRNAs and protein‐coding genes associated with perineural invasion in prostate cancer
AU2009285645B2 (en) Determining age ranges of skin samples
US20150005184A1 (en) Diagnosis of melanoma by nucleic acid analysis
US20090192045A1 (en) Molecular staging of stage ii and iii colon cancer and prognosis
WO2014176446A1 (en) Biomarkers for diagnosis and treatment of acne vulgaris
WO2012093821A2 (ko) 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
US20140100125A1 (en) Methods, Kits and Compositions for Determining Severity and Survival of Heart Failure in a Subject
Hwang et al. Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer
US20150329911A1 (en) Nucleic acid biomarkers for prostate cancer
Class et al. Patent application title: DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY NUCLEIC ACID ANALYSIS Inventors: Sherman H. Chang (San Diego, CA, US) Sherman H. Chang (San Diego, CA, US)
KR20260048449A (ko) 만성 b형 간염에 의한 조기 간암 진단을 위한 바이오마커
HK1155781A (en) Method and apparatus for determining a probability of colorectal cancer in a subject

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140513

R11 Change to the name of applicant or owner or transfer of ownership requested

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R11-R127 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TRANSFER RECORDAL REQUEST OR RESPONSE

Effective date: 20250306

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250423

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 16TH ANNIV.) - STANDARD

Year of fee payment: 16

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250509

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250509

R14 Transfer of ownership recorded

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R14-R129 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TRANSFER REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20251117

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 17TH ANNIV.) - STANDARD

Year of fee payment: 17

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20260508

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20260508

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260728