CA2701948A1 - Hiv preventive vaccine based on hiv specific antibodies - Google Patents

Hiv preventive vaccine based on hiv specific antibodies Download PDF

Info

Publication number
CA2701948A1
CA2701948A1 CA2701948A CA2701948A CA2701948A1 CA 2701948 A1 CA2701948 A1 CA 2701948A1 CA 2701948 A CA2701948 A CA 2701948A CA 2701948 A CA2701948 A CA 2701948A CA 2701948 A1 CA2701948 A1 CA 2701948A1
Authority
CA
Canada
Prior art keywords
hiv
peptides
recombinant
cag
ggt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2701948A
Other languages
English (en)
French (fr)
Inventor
Elena Yu Filinova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technologie Integrale Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2701948A1 publication Critical patent/CA2701948A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2701948A 2007-10-09 2008-10-09 Hiv preventive vaccine based on hiv specific antibodies Abandoned CA2701948A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97853607P 2007-10-09 2007-10-09
US60/978,536 2007-10-09
PCT/EP2008/008544 WO2009046984A1 (en) 2007-10-09 2008-10-09 Hiv preventive vaccine based on hiv specific antibodies

Publications (1)

Publication Number Publication Date
CA2701948A1 true CA2701948A1 (en) 2009-04-16

Family

ID=40342551

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2701948A Abandoned CA2701948A1 (en) 2007-10-09 2008-10-09 Hiv preventive vaccine based on hiv specific antibodies

Country Status (12)

Country Link
US (1) US20100215695A1 (enExample)
EP (1) EP2205736B1 (enExample)
JP (1) JP2010540674A (enExample)
KR (1) KR20100098597A (enExample)
CN (1) CN101970659A (enExample)
AU (1) AU2008309940B2 (enExample)
BR (1) BRPI0818354A2 (enExample)
CA (1) CA2701948A1 (enExample)
MX (1) MX2010003762A (enExample)
RU (1) RU2505604C2 (enExample)
WO (1) WO2009046984A1 (enExample)
ZA (1) ZA201002445B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2422618A1 (en) 2010-08-27 2012-02-29 Technologie Integrale Ltd. Animal model for the evaluation of the efficacy of an HIV vaccine
CN102212133B (zh) * 2011-03-30 2013-01-16 中国医学科学院病原生物学研究所 人源HIV抗体的Fab片段及其编码基因与应用
CN102190726B (zh) * 2011-03-30 2013-03-27 中国医学科学院病原生物学研究所 一种人源HIV抗体的Fab片段及其编码基因与应用
WO2013040564A2 (en) * 2011-09-17 2013-03-21 Nanjing University Antibody recognizing arbitrarily designed epitope of three or more amino acid residues in a peptide and method of generating thereof
US10660951B2 (en) 2012-09-17 2020-05-26 Zhiwei Allen Wu Antibody recognizing arbitrarily designed epitope of three or more amino acid residues in a peptide and method of generating thereof
EP2745845A1 (en) * 2012-12-19 2014-06-25 Centre Hospitalier Universitaire de Bordeaux A method for preventing or treating an HIV infection
TWI733652B (zh) 2014-07-11 2021-07-21 美商基利科學股份有限公司 用於治療HIV之toll樣受體調節劑
RU2600031C2 (ru) * 2014-11-11 2016-10-20 Публичное акционерное общество "Фармсинтез" Лекарственная форма специфического иммунобиологического лекарственного средства для лечения и профилактики вич инфекции и способ ее получения
EP4276106A3 (en) * 2015-05-13 2024-01-24 The United States of America as represented by the Secretary of the Department of Health and Human Services Methods and compositions for inducing an immune response using conserved element constructs
US11067583B2 (en) 2016-05-25 2021-07-20 University Of Maryland, Baltimore Methods of making active antibodies from biological fluids
CN106800603B (zh) * 2017-01-24 2020-07-28 中国食品药品检定研究院 检测抗hiv抗体的adcc活性的方法
EP3641806A4 (en) 2017-06-22 2021-06-23 University of Maryland, Baltimore BROAD NEUTRALIZING ANTIBODIES AGAINST HIV
KR20220011685A (ko) 2019-05-22 2022-01-28 길리애드 사이언시즈, 인코포레이티드 Tlr7 조절 화합물과 hiv 백신의 조합
IT202100004160A1 (it) * 2021-02-23 2022-08-23 Univ Degli Studi Milano Cellula ospite di leishmania
IT202100004172A1 (it) * 2021-02-23 2022-08-23 Univ Degli Studi Milano Nuova composizione

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2237065C2 (ru) * 2002-10-03 2004-09-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Иммуногенная библиотека химерных пептидов, мимикрирующая генетическое многообразие гипервариабельного района v3 белка оболочки gp120 вируса иммунодефицита человека
US20040109876A1 (en) * 2002-11-25 2004-06-10 Kureha Chemical Industry Co., Ltd. Vaccine composition, HIV-infection suppression factor and method for the vaccination against HIV

Also Published As

Publication number Publication date
RU2505604C2 (ru) 2014-01-27
MX2010003762A (es) 2010-09-10
AU2008309940B2 (en) 2013-11-14
CN101970659A (zh) 2011-02-09
WO2009046984A1 (en) 2009-04-16
ZA201002445B (en) 2011-03-30
AU2008309940A1 (en) 2009-04-16
JP2010540674A (ja) 2010-12-24
EP2205736B1 (en) 2014-04-02
US20100215695A1 (en) 2010-08-26
BRPI0818354A2 (pt) 2017-05-16
EP2205736A1 (en) 2010-07-14
RU2010116849A (ru) 2011-11-20
KR20100098597A (ko) 2010-09-08

Similar Documents

Publication Publication Date Title
AU2008309940B2 (en) HIV preventive vaccine based on HIV specific antibodies
Zhang et al. A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques
RU2539765C2 (ru) ВИЧ ВАКЦИНА, ОСНОВАННАЯ НА НАПРАВЛЕННОСТИ МАКСИМИЗИРОВАННЫХ Gag И Nef НА ДЕНДРИТНЫЕ КЛЕТКИ
AU729231B2 (en) Synthetic HIV genes
AP1282A (en) HIV envelope polypeptides and vaccine.
JP4805511B2 (ja) Hivに対する免疫応答における改善、または免疫応答に関する改善
US20030229214A1 (en) Vaccines comprising synthetic genes
CA2258568A1 (en) Vaccines comprising synthetic genes
KR20070028291A (ko) 컨센서스/원형 면역원
Lopes et al. Phage display: an important tool in the discovery of peptides with anti-HIV activity
Vzorov et al. Effects of modification of the HIV-1 Env cytoplasmic tail on immunogenicity of VLP vaccines
US8754015B2 (en) Modified phage for displaying post-translationally modified proteins and uses thereof
JP2018150370A (ja) レンチウイルスの変異envタンパク質及び薬物としてのその使用
US20080306244A1 (en) Renta: an HIV immunogen and uses thereof
KR101756202B1 (ko) 신규한 gp41 항원
WO2006057454A1 (en) A method of prime-boost vaccination
Josyula Venkata Investigation of B cell and T follicular helper cell responses following priming with immunogens designed to trigger VRC01-class neutralizing antibodies to HIV-1
HK1151554A (en) Hiv preventive vaccine based on hiv specific antibodies
Shrivastava et al. ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates
Zimmer Methods for development and characterization of HIV-1 envelope immunogens
US20030087225A1 (en) Synthetic HIV genes
US20100303858A1 (en) Chimeric HIV-1 Glycoproteins and Their Biological Applications
Abduljawad Optimizing a Universal Mosaic T cell vaccine for HIV-1
Benen HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 AND DISPLAY SYSTEMS FOR THEIR AFFINITY MATURATION
Benen Novel Immunogens based on the gp41 protein of Human Immunodeficiency Virus type 1 and Display Systems for their Affinity Maturation

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150521