CA2699550C - Method of inhibiting clostridium difficile by administration of oritavancin - Google Patents

Method of inhibiting clostridium difficile by administration of oritavancin Download PDF

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Publication number
CA2699550C
CA2699550C CA2699550A CA2699550A CA2699550C CA 2699550 C CA2699550 C CA 2699550C CA 2699550 A CA2699550 A CA 2699550A CA 2699550 A CA2699550 A CA 2699550A CA 2699550 C CA2699550 C CA 2699550C
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CA
Canada
Prior art keywords
glycopeptide antibiotic
effective amount
therapeutically effective
body weight
difficile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2699550A
Other languages
English (en)
French (fr)
Other versions
CA2699550A1 (en
Inventor
Mark Harvey Wilcox
Simon Baines
Dario Lehoux
Thomas R. Parr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Melinta Subsidiary Corp
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of CA2699550A1 publication Critical patent/CA2699550A1/en
Application granted granted Critical
Publication of CA2699550C publication Critical patent/CA2699550C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2699550A 2007-09-12 2008-09-11 Method of inhibiting clostridium difficile by administration of oritavancin Active CA2699550C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97176607P 2007-09-12 2007-09-12
US60/971,766 2007-09-12
PCT/US2008/075949 WO2009036121A1 (en) 2007-09-12 2008-09-11 Method of inhibiting clostridium difficile by administration of oritavancin

Publications (2)

Publication Number Publication Date
CA2699550A1 CA2699550A1 (en) 2009-03-19
CA2699550C true CA2699550C (en) 2020-08-18

Family

ID=40452464

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2699550A Active CA2699550C (en) 2007-09-12 2008-09-11 Method of inhibiting clostridium difficile by administration of oritavancin

Country Status (9)

Country Link
US (3) US8518873B2 (enExample)
EP (1) EP2195004B1 (enExample)
JP (1) JP5591112B2 (enExample)
CN (1) CN102316885A (enExample)
AU (1) AU2008298987B2 (enExample)
CA (1) CA2699550C (enExample)
EA (1) EA017564B1 (enExample)
ES (1) ES2535928T3 (enExample)
WO (1) WO2009036121A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102316885A (zh) * 2007-09-12 2012-01-11 塔尔甘塔治疗公司 通过奥利万星给药抑制艰难梭菌的方法
ES2884673T3 (es) 2008-04-08 2021-12-10 Melinta Therapeutics Inc Oritavancina para inhibir y tratar biopelículas
CN102573882A (zh) 2009-04-28 2012-07-11 塔尔甘塔治疗公司 用奥利万星治疗细菌感染的方法
JP5986416B2 (ja) * 2012-04-11 2016-09-06 花王株式会社 皮膚外用剤
FI3628161T3 (fi) 2012-11-23 2023-05-25 Seres Therapeutics Inc Synergisiä bakteerikoostumuksia ja niiden valmistusmenetelmiä ja käyttö
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
HK1218560A1 (zh) 2013-02-04 2017-02-24 Seres Therapeutics, Inc. 组成与方法
US11185562B2 (en) * 2013-02-04 2021-11-30 Seres Therapeutics, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
US10076546B2 (en) 2013-03-15 2018-09-18 Seres Therapeutics, Inc. Network-based microbial compositions and methods
CA2931317C (en) 2013-11-25 2023-08-22 Seres Therapeutics, Inc. Synergistic bacterial compositions and methods of production and use thereof
WO2015095241A2 (en) 2013-12-16 2015-06-25 Seres Health, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
US10191380B2 (en) * 2014-10-14 2019-01-29 Az Electronic Materials (Luxembourg) S.A.R.L. Composition for resist patterning and method for forming pattern using same
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
AU2017221435A1 (en) * 2016-02-18 2018-09-06 Melinta Therapeutics, Inc. Oritavancin formulations
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
EA201892413A1 (ru) 2016-05-09 2019-05-31 Кселлия Фармасьютикалз Апс Стабилизированные препараты гликопептидного антибиотика
MX2020001774A (es) 2017-08-14 2020-09-09 Seres Therapeutics Inc Composiciones y métodos para tratar enfermedad colestásica.
RU2020117775A (ru) 2017-10-30 2021-12-01 Серес Терапеутикс, Инк. Композиции и способы для лечения устойчивости к антибиотикам
US20220096510A1 (en) * 2018-08-17 2022-03-31 Universidad Andrés Bello Method and pharmacological composition for the prevention of recurrent infections caused by clostridium difficile
KR102444119B1 (ko) * 2020-04-22 2022-09-16 주식회사 인트론바이오테크놀로지 클로스트리디오이데스 디피실리 균에 대하여 용균 활성을 갖는 항균단백질 cdl200

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2961184B2 (ja) * 1990-05-07 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
GB0212622D0 (en) * 2002-05-31 2002-07-10 Natural Technologies Group Ltd Bacterial transforming agent
US7317001B2 (en) * 2002-06-06 2008-01-08 Oscient Pharmaceuticals Corporation Use of ramoplanin to treat diseases associated with the use of antibiotics
WO2004019907A1 (en) * 2002-08-29 2004-03-11 Activbiotics, Inc. Methods and reagents for treating infections of clostridium difficile and diseases associated therewith
AU2004308399A1 (en) * 2003-12-23 2005-07-14 Activbiotics, Inc. Rifamycin analogs and uses thereof
CA2641854A1 (en) * 2006-02-08 2007-08-16 Biosynexus Incorporated Neutralization of bacterial spores
GB0714030D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
CN102316885A (zh) * 2007-09-12 2012-01-11 塔尔甘塔治疗公司 通过奥利万星给药抑制艰难梭菌的方法

Also Published As

Publication number Publication date
US9220749B2 (en) 2015-12-29
ES2535928T3 (es) 2015-05-19
JP2010539179A (ja) 2010-12-16
CA2699550A1 (en) 2009-03-19
AU2008298987B2 (en) 2013-12-05
US8629100B2 (en) 2014-01-14
EA017564B1 (ru) 2013-01-30
WO2009036121A1 (en) 2009-03-19
AU2008298987A1 (en) 2009-03-19
US20140100157A1 (en) 2014-04-10
EA201000383A1 (ru) 2010-10-29
EP2195004A1 (en) 2010-06-16
JP5591112B2 (ja) 2014-09-17
US20100311646A1 (en) 2010-12-09
CN102316885A (zh) 2012-01-11
US20130310308A1 (en) 2013-11-21
EP2195004A4 (en) 2011-12-28
EP2195004B1 (en) 2015-04-01
US8518873B2 (en) 2013-08-27
BRPI0816662A2 (pt) 2017-06-13

Similar Documents

Publication Publication Date Title
CA2699550C (en) Method of inhibiting clostridium difficile by administration of oritavancin
ES2884673T3 (es) Oritavancina para inhibir y tratar biopelículas
CA2736860C (en) Methods of treatment using single doses of oritavancin
KR20010022237A (ko) 리소스타핀을 단독 또는 항생제와의 조합으로 포함하는포도상구균 감염 치료용 약제학적 조성물
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BRPI0816662B1 (pt) Método in vitro para inibir crescimento de esporo de c. difficile
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