CA2697024C - Bilayers - Google Patents
Bilayers Download PDFInfo
- Publication number
- CA2697024C CA2697024C CA2697024A CA2697024A CA2697024C CA 2697024 C CA2697024 C CA 2697024C CA 2697024 A CA2697024 A CA 2697024A CA 2697024 A CA2697024 A CA 2697024A CA 2697024 C CA2697024 C CA 2697024C
- Authority
- CA
- Canada
- Prior art keywords
- bilayer
- hydrated
- lipid
- support
- hydrated support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
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| PCT/GB2008/002805 WO2009024775A1 (en) | 2007-08-21 | 2008-08-19 | Bilayers |
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| WO (1) | WO2009024775A1 (https=) |
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| PT2347775T (pt) | 2005-12-13 | 2020-07-14 | The President And Fellows Of Harvard College | Estruturas em andaime para transplante celular |
| WO2008102120A1 (en) | 2007-02-20 | 2008-08-28 | Oxford Nanopore Technologies Limited | Lipid bilayer sensor system |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| GB0913823D0 (en) * | 2009-08-07 | 2009-09-16 | Isis Innovation | Bilayers |
| US8313956B2 (en) | 2010-03-09 | 2012-11-20 | Nokia Corporation | Apparatus and associated methods |
| JP6104806B2 (ja) | 2010-10-06 | 2017-03-29 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル |
| AU2012215135B9 (en) | 2011-02-11 | 2017-03-09 | Oxford Nanopore Technologies Limited | Mutant pores |
| EP2697394A4 (en) | 2011-04-12 | 2015-01-14 | Electronic Biosciences Inc | CHEMICALLY MODIFIED NANOPORA DEVICES AT A SPECIFIC SITE |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| GB201119032D0 (en) | 2011-11-03 | 2011-12-14 | Isis Innovation | Multisomes: encapsulated droplet networks |
| GB201202519D0 (en) | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
| JP6271505B2 (ja) | 2012-04-10 | 2018-01-31 | オックスフォード ナノポール テクノロジーズ リミテッド | 変異体ライセニンポア |
| CN104244929B (zh) | 2012-04-16 | 2017-04-05 | 哈佛学院董事会 | 用于调节免疫反应的介孔二氧化硅组合物 |
| US20150204873A1 (en) * | 2012-06-18 | 2015-07-23 | Electonic Biosciences, Inc. | Cell-free assay device and methods of use |
| GB201219196D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Droplet assembly method |
| GB201219201D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Hydrogel network |
| EP2911771B1 (en) * | 2012-10-26 | 2017-01-18 | Oxford Nanopore Technologies Limited | Droplet interfaces |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
| EP2928610A2 (en) * | 2012-12-07 | 2015-10-14 | Isis Innovation Limited | Droplet assembly by 3d printing |
| GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
| CN103435269A (zh) * | 2013-08-21 | 2013-12-11 | 哈尔滨工业大学 | 一种固体支撑仿生膜体系的制备方法 |
| JP6749243B2 (ja) | 2014-01-22 | 2020-09-02 | オックスフォード ナノポール テクノロジーズ リミテッド | １つまたは複数のポリヌクレオチド結合タンパク質を標的ポリヌクレオチドに付着させる方法 |
| JP7348708B2 (ja) | 2014-04-30 | 2023-09-21 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 組み合わせワクチン装置および癌細胞を殺滅する方法 |
| US10443097B2 (en) | 2014-05-02 | 2019-10-15 | Oxford Nanopore Technologies Ltd. | Method of improving the movement of a target polynucleotide with respect to a transmembrane pore |
| WO2016009180A1 (en) | 2014-07-14 | 2016-01-21 | Isis Innovation Limited | Measurement of analytes with membrane channel molecules, and bilayer arrays |
| US10400014B2 (en) | 2014-09-01 | 2019-09-03 | Oxford Nanopore Technologies Ltd. | Mutant CsgG pores |
| US10266885B2 (en) | 2014-10-07 | 2019-04-23 | Oxford Nanopore Technologies Ltd. | Mutant pores |
| GB201418512D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Electrical device with detachable components |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| GB201502810D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Method |
| GB201502809D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Mutant pore |
| WO2016164705A1 (en) | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Immune cell trapping devices and methods for making and using the same |
| US11169138B2 (en) | 2015-04-14 | 2021-11-09 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
| US10641764B2 (en) | 2015-07-02 | 2020-05-05 | The University Of Massachusetts | Membrane and droplet-interface bilayer systems and methods |
| US10481120B1 (en) | 2015-08-06 | 2019-11-19 | University Of Tennessee Research Foundation | Droplet based measurement of specific capacitance and interfacial tensions |
| KR102837999B1 (ko) | 2015-12-08 | 2025-07-24 | 카트호리이케 유니버시타이트 로이펜 | 변형된 나노세공, 그를 포함하는 조성물, 및 그의 용도 |
| EP3411475B1 (en) | 2016-02-06 | 2025-08-27 | President and Fellows of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
| US10371610B2 (en) * | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
| KR20170099738A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 패치 및 그 제조 방법 |
| KR102478639B1 (ko) | 2016-02-23 | 2022-12-19 | 노을 주식회사 | 표지 물질을 저장하는 패치, 이를 이용하는 조직 진단 방법 및 장치 |
| AU2017225374B2 (en) | 2016-03-02 | 2020-03-05 | Oxford Nanopore Technologies Limited | Mutant pore |
| US10155979B2 (en) | 2016-03-30 | 2018-12-18 | Roche Molecular Systems, Inc. | Non-destructive bilayer monitoring using measurement of bilayer response to electrical stimulus |
| US10233486B2 (en) | 2016-03-30 | 2019-03-19 | Roche Sequencing Solutions, Inc. | Method for inline bilayer capacitance monitoring |
| US10465240B2 (en) | 2016-03-30 | 2019-11-05 | Roche Sequencing Solutions, Inc. | Electrical enhancement of bilayer formation |
| WO2017174990A1 (en) | 2016-04-06 | 2017-10-12 | Oxford Nanopore Technologies Limited | Mutant pore |
| GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| CN115404196A (zh) | 2016-07-13 | 2022-11-29 | 哈佛学院院长等 | 抗原呈递细胞模拟支架及其制备和使用方法 |
| CN110418651A (zh) | 2016-08-02 | 2019-11-05 | 哈佛学院院长等 | 用于调节免疫应答的生物材料 |
| GB201615741D0 (en) * | 2016-09-15 | 2016-11-02 | Univ College Cardiff Consultants Ltd | Artificial cells |
| FR3061440B1 (fr) * | 2017-01-05 | 2021-02-12 | Centre Nat Rech Scient | Procede de fabrication d’une membrane multicouche sur support solide a base de copolymere a blocs amphiphile |
| CN108329471A (zh) * | 2017-01-19 | 2018-07-27 | 天津大学 | 一种锂硫电池正极活性材料异戊烯醇-硫共聚物及制备方法 |
| GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
| WO2019002893A1 (en) | 2017-06-30 | 2019-01-03 | Vib Vzw | NEW PROTEIN PORES |
| JP7058858B2 (ja) * | 2017-10-19 | 2022-04-25 | 地方独立行政法人神奈川県立産業技術総合研究所 | 脂質二重膜形成器具及びそれを用いた脂質二重膜形成方法 |
| DE102017126732A1 (de) * | 2017-11-14 | 2019-05-16 | Endress+Hauser Conducta Gmbh+Co. Kg | Sensormembran, Sensor, ein Messgerät umfassend den Sensor und Verwendung des Sensors |
| GB2568895B (en) | 2017-11-29 | 2021-10-27 | Oxford Nanopore Tech Ltd | Microfluidic device |
| GB2569630B (en) | 2017-12-21 | 2022-10-12 | Sharp Life Science Eu Ltd | Droplet Interfaces in Electro-wetting Devices |
| GB2574048B (en) | 2018-05-24 | 2021-06-16 | Oxford Nanopore Tech Ltd | Nanopore sensor component with electrostatic discharge protection |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| US11789006B2 (en) | 2019-03-12 | 2023-10-17 | Oxford Nanopore Technologies Plc | Nanopore sensing device, components and method of operation |
| US12135326B2 (en) | 2019-05-29 | 2024-11-05 | Nanjing University | Detection of analytes by nanopore without using electrodes |
| WO2021061837A1 (en) | 2019-09-23 | 2021-04-01 | President And Fellows Of Harvard College | Biomaterial-based antigen free vaccine and the use thereof |
| CN112831395B (zh) * | 2019-11-25 | 2024-01-16 | 深圳华大生命科学研究院 | 用于纳米孔测序的类细胞膜 |
| GB202004944D0 (en) | 2020-04-03 | 2020-05-20 | King S College London | Method |
| WO2022013551A1 (en) | 2020-07-17 | 2022-01-20 | Oxford Nanopore Technologies Limited | Nanopore sensing device |
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| JPH067737A (ja) * | 1992-06-30 | 1994-01-18 | Junjiro Aoki | 累積膜の連続製造方法 |
| EP1373550A1 (en) * | 2001-03-14 | 2004-01-02 | Biacore AB | Method of preparing supported lipid film membranes and use thereof |
| JP4394916B2 (ja) * | 2003-09-19 | 2010-01-06 | 独立行政法人科学技術振興機構 | 人工脂質二重膜の形成装置および人工脂質二重膜の形成方法、並びにその利用 |
| JP4394917B2 (ja) * | 2003-09-19 | 2010-01-06 | 独立行政法人科学技術振興機構 | 人工脂質二重膜を有する電流測定装置 |
| JP2005114576A (ja) * | 2003-10-08 | 2005-04-28 | Hitachi Software Eng Co Ltd | 両親媒性分子固定化ビーズ、その製造方法、及びキャピラリビーズアレイのビーズ配列方法 |
| GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
| US8211712B2 (en) | 2005-03-29 | 2012-07-03 | The Board Of Trustees Of The Leland Stanford Junior University | Method of fabricating lipid bilayer membranes on solid supports |
| ATE457823T1 (de) | 2005-05-20 | 2010-03-15 | Aquaporin Aps | Membran zum filtrieren von wasser |
| JP5114702B2 (ja) | 2005-07-29 | 2013-01-09 | 国立大学法人 東京大学 | 両親媒性単分子膜の接触による二分子膜の形成方法およびその装置 |
| EP1931981A1 (en) | 2005-09-07 | 2008-06-18 | Agresearch Limited | A method of manufacture |
| GB0614835D0 (en) * | 2006-07-26 | 2006-09-06 | Isis Innovation | Formation of bilayers of amphipathic molecules |
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| US20130129910A1 (en) | 2013-05-23 |
| US20110041978A1 (en) | 2011-02-24 |
| CN101821626B (zh) | 2015-04-08 |
| EP2183594B1 (en) | 2018-11-07 |
| US8784929B2 (en) | 2014-07-22 |
| EP2183594A1 (en) | 2010-05-12 |
| JP5797405B2 (ja) | 2015-10-21 |
| CN101821626A (zh) | 2010-09-01 |
| JP2010536551A (ja) | 2010-12-02 |
| WO2009024775A1 (en) | 2009-02-26 |
| WO2009024775A8 (en) | 2009-12-03 |
| CA2697024A1 (en) | 2009-02-26 |
| GB0716264D0 (en) | 2007-09-26 |
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