CA2689598A1 - Method of manufacturing expansile filamentous embolization devices - Google Patents
Method of manufacturing expansile filamentous embolization devices Download PDFInfo
- Publication number
- CA2689598A1 CA2689598A1 CA2689598A CA2689598A CA2689598A1 CA 2689598 A1 CA2689598 A1 CA 2689598A1 CA 2689598 A CA2689598 A CA 2689598A CA 2689598 A CA2689598 A CA 2689598A CA 2689598 A1 CA2689598 A1 CA 2689598A1
- Authority
- CA
- Canada
- Prior art keywords
- carrier
- expansile
- embolizing
- polymer
- hydrophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000010102 embolization Effects 0.000 title abstract description 94
- 238000004519 manufacturing process Methods 0.000 title description 5
- 238000000034 method Methods 0.000 claims abstract description 102
- 229920000642 polymer Polymers 0.000 claims description 77
- 230000001954 sterilising effect Effects 0.000 claims description 15
- 238000004659 sterilization and disinfection Methods 0.000 claims description 15
- 229920001477 hydrophilic polymer Polymers 0.000 claims description 10
- 210000003101 oviduct Anatomy 0.000 claims description 9
- 230000001131 transforming effect Effects 0.000 claims 6
- 230000008878 coupling Effects 0.000 claims 2
- 238000010168 coupling process Methods 0.000 claims 2
- 238000005859 coupling reaction Methods 0.000 claims 2
- 230000000887 hydrating effect Effects 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 abstract description 83
- 239000003814 drug Substances 0.000 abstract description 16
- 230000004044 response Effects 0.000 abstract description 13
- 229940124597 therapeutic agent Drugs 0.000 abstract description 12
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract description 6
- 238000000465 moulding Methods 0.000 abstract description 6
- 239000006261 foam material Substances 0.000 abstract description 5
- 230000007613 environmental effect Effects 0.000 abstract description 4
- 229910000990 Ni alloy Inorganic materials 0.000 abstract description 2
- 229910001069 Ti alloy Inorganic materials 0.000 abstract description 2
- 230000002792 vascular Effects 0.000 description 66
- 206010002329 Aneurysm Diseases 0.000 description 53
- 239000000463 material Substances 0.000 description 34
- 239000000243 solution Substances 0.000 description 30
- 239000000178 monomer Substances 0.000 description 29
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 27
- 230000036571 hydration Effects 0.000 description 21
- 238000006703 hydration reaction Methods 0.000 description 21
- 230000003073 embolic effect Effects 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 239000003795 chemical substances by application Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 10
- 239000003431 cross linking reagent Substances 0.000 description 10
- 229910052751 metal Inorganic materials 0.000 description 10
- 239000002184 metal Substances 0.000 description 10
- 239000000203 mixture Substances 0.000 description 10
- 210000003739 neck Anatomy 0.000 description 10
- 230000036961 partial effect Effects 0.000 description 10
- 229910052697 platinum Inorganic materials 0.000 description 10
- 239000004372 Polyvinyl alcohol Substances 0.000 description 9
- 229920002451 polyvinyl alcohol Polymers 0.000 description 9
- 230000008569 process Effects 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 8
- 239000006260 foam Substances 0.000 description 8
- 210000004204 blood vessel Anatomy 0.000 description 7
- -1 e.g. Substances 0.000 description 7
- 239000012530 fluid Substances 0.000 description 7
- 239000007943 implant Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 150000001412 amines Chemical class 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 238000011065 in-situ storage Methods 0.000 description 6
- 238000011534 incubation Methods 0.000 description 6
- 229910001000 nickel titanium Inorganic materials 0.000 description 6
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 125000002843 carboxylic acid group Chemical group 0.000 description 5
- 235000019441 ethanol Nutrition 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 125000003277 amino group Chemical group 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 4
- 150000001735 carboxylic acids Chemical class 0.000 description 4
- 230000007547 defect Effects 0.000 description 4
- 230000018044 dehydration Effects 0.000 description 4
- 238000006297 dehydration reaction Methods 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000003999 initiator Substances 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 238000013508 migration Methods 0.000 description 4
- 239000008188 pellet Substances 0.000 description 4
- 210000002381 plasma Anatomy 0.000 description 4
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 4
- 239000004926 polymethyl methacrylate Substances 0.000 description 4
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 4
- 239000004810 polytetrafluoroethylene Substances 0.000 description 4
- 230000002028 premature Effects 0.000 description 4
- 230000000717 retained effect Effects 0.000 description 4
- 125000006850 spacer group Chemical group 0.000 description 4
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 4
- 239000011800 void material Substances 0.000 description 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 3
- 210000000601 blood cell Anatomy 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 125000000524 functional group Chemical group 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 238000010348 incorporation Methods 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 238000002483 medication Methods 0.000 description 3
- 229910001092 metal group alloy Inorganic materials 0.000 description 3
- 230000005012 migration Effects 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 230000000452 restraining effect Effects 0.000 description 3
- 229910000679 solder Inorganic materials 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 230000002885 thrombogenetic effect Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 229910052721 tungsten Inorganic materials 0.000 description 3
- 239000010937 tungsten Substances 0.000 description 3
- 238000012800 visualization Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 2
- 208000008883 Patent Foramen Ovale Diseases 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 229910001260 Pt alloy Inorganic materials 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 229910001080 W alloy Inorganic materials 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- ROOXNKNUYICQNP-UHFFFAOYSA-N ammonium persulfate Chemical compound [NH4+].[NH4+].[O-]S(=O)(=O)OOS([O-])(=O)=O ROOXNKNUYICQNP-UHFFFAOYSA-N 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 208000013914 atrial heart septal defect Diseases 0.000 description 2
- 239000000560 biocompatible material Substances 0.000 description 2
- 229920000249 biocompatible polymer Polymers 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000005595 deprotonation Effects 0.000 description 2
- 238000010537 deprotonation reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000004872 foam stabilizing agent Substances 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 210000005248 left atrial appendage Anatomy 0.000 description 2
- 239000004005 microsphere Substances 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 208000003278 patent ductus arteriosus Diseases 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 239000003505 polymerization initiator Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000005588 protonation Effects 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229910052715 tantalum Inorganic materials 0.000 description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 238000007794 visualization technique Methods 0.000 description 2
- WROUWQQRXUBECT-UHFFFAOYSA-N 2-ethylacrylic acid Chemical compound CCC(=C)C(O)=O WROUWQQRXUBECT-UHFFFAOYSA-N 0.000 description 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- 208000022211 Arteriovenous Malformations Diseases 0.000 description 1
- 206010003226 Arteriovenous fistula Diseases 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- 229920004934 Dacron® Polymers 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 1
- 102000008946 Fibrinogen Human genes 0.000 description 1
- 108010049003 Fibrinogen Proteins 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 201000008450 Intracranial aneurysm Diseases 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 1
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 206010047050 Vascular anomaly Diseases 0.000 description 1
- 206010053649 Vascular rupture Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910001870 ammonium persulfate Inorganic materials 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000003409 anti-rejection Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229960005475 antiinfective agent Drugs 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 239000008365 aqueous carrier Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000005744 arteriovenous malformation Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 239000012867 bioactive agent Substances 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- WMWLMWRWZQELOS-UHFFFAOYSA-N bismuth(III) oxide Inorganic materials O=[Bi]O[Bi]=O WMWLMWRWZQELOS-UHFFFAOYSA-N 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000002274 desiccant Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 239000004715 ethylene vinyl alcohol Substances 0.000 description 1
- 229940012952 fibrinogen Drugs 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 230000005251 gamma ray Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical group OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- QRWOVIRDHQJFDB-UHFFFAOYSA-N isobutyl cyanoacrylate Chemical compound CC(C)COC(=O)C(=C)C#N QRWOVIRDHQJFDB-UHFFFAOYSA-N 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 235000015927 pasta Nutrition 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920005594 polymer fiber Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000003229 sclerosing agent Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000005944 tissue migration Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000011277 treatment modality Methods 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
- B29C70/68—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts by incorporating or moulding on preformed parts, e.g. inserts or layers, e.g. foam blocks
- B29C70/74—Moulding material on a relatively small portion of the preformed part, e.g. outsert moulding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
- A61B17/12118—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12154—Coils or wires having stretch limiting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12163—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a string of elements connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
- A61B17/1219—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices expandable in contact with liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00526—Methods of manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7542—Catheters
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Composite Materials (AREA)
- Mechanical Engineering (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/867,340 US6602261B2 (en) | 1999-10-04 | 2001-05-29 | Filamentous embolic device with expansile elements |
| US09/867,340 | 2001-05-29 | ||
| CA002449055A CA2449055C (en) | 2001-05-29 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
| US10/157,621 | 2002-05-29 | ||
| US10/157,621 US7014645B2 (en) | 1999-10-04 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002449055A Division CA2449055C (en) | 2001-05-29 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2689598A1 true CA2689598A1 (en) | 2002-12-05 |
Family
ID=26854315
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2689598A Abandoned CA2689598A1 (en) | 2001-05-29 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
| CA002449055A Expired - Fee Related CA2449055C (en) | 2001-05-29 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002449055A Expired - Fee Related CA2449055C (en) | 2001-05-29 | 2002-05-29 | Method of manufacturing expansile filamentous embolization devices |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7014645B2 (enExample) |
| EP (2) | EP2319430B1 (enExample) |
| JP (1) | JP4383746B2 (enExample) |
| AT (1) | ATE516759T1 (enExample) |
| AU (3) | AU2002344223B2 (enExample) |
| CA (2) | CA2689598A1 (enExample) |
| ES (1) | ES2441341T3 (enExample) |
| WO (1) | WO2002096302A1 (enExample) |
Families Citing this family (242)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8795332B2 (en) | 2002-09-30 | 2014-08-05 | Ethicon, Inc. | Barbed sutures |
| US6176240B1 (en) * | 1995-06-07 | 2001-01-23 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and their delivery |
| US6705323B1 (en) | 1995-06-07 | 2004-03-16 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
| US5931855A (en) | 1997-05-21 | 1999-08-03 | Frank Hoffman | Surgical methods using one-way suture |
| US6015424A (en) * | 1998-04-28 | 2000-01-18 | Microvention, Inc. | Apparatus and method for vascular embolization |
| US7128073B1 (en) | 1998-11-06 | 2006-10-31 | Ev3 Endovascular, Inc. | Method and device for left atrial appendage occlusion |
| US7044134B2 (en) | 1999-11-08 | 2006-05-16 | Ev3 Sunnyvale, Inc | Method of implanting a device in the left atrial appendage |
| US6309384B1 (en) | 1999-02-01 | 2001-10-30 | Adiana, Inc. | Method and apparatus for tubal occlusion |
| US8702727B1 (en) | 1999-02-01 | 2014-04-22 | Hologic, Inc. | Delivery catheter with implant ejection mechanism |
| US6280457B1 (en) * | 1999-06-04 | 2001-08-28 | Scimed Life Systems, Inc. | Polymer covered vaso-occlusive devices and methods of producing such devices |
| US8048104B2 (en) | 2000-10-30 | 2011-11-01 | Dendron Gmbh | Device for the implantation of occlusion spirals |
| US6994092B2 (en) | 1999-11-08 | 2006-02-07 | Ev3 Sunnyvale, Inc. | Device for containing embolic material in the LAA having a plurality of tissue retention structures |
| US8313504B2 (en) * | 2000-09-18 | 2012-11-20 | Cordis Corporation | Foam matrix embolization device |
| US7033374B2 (en) * | 2000-09-26 | 2006-04-25 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
| US6878384B2 (en) | 2001-03-13 | 2005-04-12 | Microvention, Inc. | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
| US7056331B2 (en) | 2001-06-29 | 2006-06-06 | Quill Medical, Inc. | Suture method |
| US7572288B2 (en) * | 2001-07-20 | 2009-08-11 | Microvention, Inc. | Aneurysm treatment device and method of use |
| EP1526815A1 (en) | 2002-07-31 | 2005-05-04 | MicroVention, Inc. | Three element coaxial vaso-occlusive device |
| US6773450B2 (en) | 2002-08-09 | 2004-08-10 | Quill Medical, Inc. | Suture anchor and method |
| US20040088003A1 (en) * | 2002-09-30 | 2004-05-06 | Leung Jeffrey C. | Barbed suture in combination with surgical needle |
| US8100940B2 (en) | 2002-09-30 | 2012-01-24 | Quill Medical, Inc. | Barb configurations for barbed sutures |
| US20040122349A1 (en) | 2002-12-20 | 2004-06-24 | Lafontaine Daniel M. | Closure device with textured surface |
| US8709038B2 (en) * | 2002-12-20 | 2014-04-29 | Boston Scientific Scimed, Inc. | Puncture hole sealing device |
| KR100721049B1 (ko) * | 2003-01-10 | 2007-05-23 | 가부시키가이샤 가네카 | 색전 형성용 체내 유치 코일 |
| JP2004261218A (ja) * | 2003-02-07 | 2004-09-24 | Yasuhiko Tabata | 血管塞栓用組成物 |
| US8043321B2 (en) | 2003-07-24 | 2011-10-25 | Boston Scientific Scimed, Inc. | Embolic coil |
| US7371228B2 (en) * | 2003-09-19 | 2008-05-13 | Medtronic Vascular, Inc. | Delivery of therapeutics to treat aneurysms |
| US20050107867A1 (en) * | 2003-11-17 | 2005-05-19 | Taheri Syde A. | Temporary absorbable venous occlusive stent and superficial vein treatment method |
| US20080109057A1 (en) * | 2003-12-10 | 2008-05-08 | Calabria Marie F | Multiple point detacher system |
| DE102004003265A1 (de) | 2004-01-21 | 2005-08-11 | Dendron Gmbh | Vorrichtung zur Implantation von elektrisch isolierten Okklusionswendeln |
| US9238127B2 (en) | 2004-02-25 | 2016-01-19 | Femasys Inc. | Methods and devices for delivering to conduit |
| US8052669B2 (en) | 2004-02-25 | 2011-11-08 | Femasys Inc. | Methods and devices for delivery of compositions to conduits |
| US8048086B2 (en) | 2004-02-25 | 2011-11-01 | Femasys Inc. | Methods and devices for conduit occlusion |
| US8048101B2 (en) | 2004-02-25 | 2011-11-01 | Femasys Inc. | Methods and devices for conduit occlusion |
| US20050216049A1 (en) * | 2004-03-29 | 2005-09-29 | Jones Donald K | Vascular occlusive device with elastomeric bioresorbable coating |
| US7416757B2 (en) * | 2004-04-08 | 2008-08-26 | Cordis Neurovascular, Inc. | Method of making active embolic coil |
| US8801746B1 (en) | 2004-05-04 | 2014-08-12 | Covidien Lp | System and method for delivering a left atrial appendage containment device |
| SG164370A1 (en) | 2004-05-14 | 2010-09-29 | Quill Medical Inc | Suture methods and devices |
| US20050267510A1 (en) * | 2004-05-26 | 2005-12-01 | Nasser Razack | Device for the endovascular treatment of intracranial aneurysms |
| US20060036211A1 (en) * | 2004-07-29 | 2006-02-16 | X-Sten, Inc. | Spinal ligament modification kit |
| US7402320B2 (en) | 2004-08-31 | 2008-07-22 | Vnus Medical Technologies, Inc. | Apparatus, material compositions, and methods for permanent occlusion of a hollow anatomical structure |
| US8845676B2 (en) | 2004-09-22 | 2014-09-30 | Micro Therapeutics | Micro-spiral implantation device |
| US7879064B2 (en) | 2004-09-22 | 2011-02-01 | Micro Therapeutics, Inc. | Medical implant |
| US7201918B2 (en) * | 2004-11-16 | 2007-04-10 | Microvention, Inc. | Compositions, systems and methods for treatment of defects in blood vessels |
| US8425550B2 (en) * | 2004-12-01 | 2013-04-23 | Boston Scientific Scimed, Inc. | Embolic coils |
| US20060206139A1 (en) * | 2005-01-19 | 2006-09-14 | Tekulve Kurt J | Vascular occlusion device |
| EP1841368B1 (en) | 2005-01-25 | 2015-06-10 | Covidien LP | Structures for permanent occlusion of a hollow anatomical structure |
| US20060178696A1 (en) * | 2005-02-04 | 2006-08-10 | Porter Stephen C | Macroporous materials for use in aneurysms |
| US20070001346A1 (en) * | 2005-06-30 | 2007-01-04 | Murty Vyakarnam | Active embolization device |
| US8109913B2 (en) * | 2005-07-11 | 2012-02-07 | Dsm Ip Assets B.V. | Coiled wire for the controlled release of drugs to the eye |
| ATE495701T1 (de) | 2005-07-29 | 2011-02-15 | Vertos Medical Inc | Perkutane gewebeexzisionsvorrichtungen |
| US7972359B2 (en) | 2005-09-16 | 2011-07-05 | Atritech, Inc. | Intracardiac cage and method of delivering same |
| WO2007041131A2 (en) * | 2005-09-30 | 2007-04-12 | Cook Incorporated | Coated vaso-occlusion device |
| US20070123890A1 (en) * | 2005-11-04 | 2007-05-31 | X-Sten, Corp. | Tissue retrieval devices and methods |
| US7927676B2 (en) * | 2006-03-31 | 2011-04-19 | Codman & Shurtleff, Inc. | Plasma-treated vascular occlusion devices and methods |
| US20070239194A1 (en) * | 2006-04-05 | 2007-10-11 | Boston Scientific Scimed, Inc. | Vaso-occlusive devices having expandable fibers |
| US8864790B2 (en) | 2006-04-17 | 2014-10-21 | Covidien Lp | System and method for mechanically positioning intravascular implants |
| US8777979B2 (en) | 2006-04-17 | 2014-07-15 | Covidien Lp | System and method for mechanically positioning intravascular implants |
| US9017361B2 (en) | 2006-04-20 | 2015-04-28 | Covidien Lp | Occlusive implant and methods for hollow anatomical structure |
| US7942830B2 (en) | 2006-05-09 | 2011-05-17 | Vertos Medical, Inc. | Ipsilateral approach to minimally invasive ligament decompression procedure |
| JP2010500917A (ja) | 2006-06-15 | 2010-01-14 | マイクロベンション， インコーポレイテッド | 膨張性ポリマーで構成される塞栓形成デバイス |
| US20070299461A1 (en) * | 2006-06-21 | 2007-12-27 | Boston Scientific Scimed, Inc. | Embolic coils and related components, systems, and methods |
| USD606654S1 (en) | 2006-07-31 | 2009-12-22 | Vertos Medical, Inc. | Tissue excision device |
| USD620593S1 (en) | 2006-07-31 | 2010-07-27 | Vertos Medical, Inc. | Tissue excision device |
| US20080221383A1 (en) * | 2007-02-12 | 2008-09-11 | Vertos Medical, Inc. | Tissue excision devices and methods |
| KR20100015520A (ko) | 2007-03-13 | 2010-02-12 | 마이크로 테라퓨틱스 인코포레이티드 | 코일과 펴짐방지 부재를 포함하는 임플란트 |
| KR20100015521A (ko) * | 2007-03-13 | 2010-02-12 | 마이크로 테라퓨틱스 인코포레이티드 | 임플란트, 맨드릴, 및 임플란트 형성방법 |
| US20080255612A1 (en) * | 2007-04-13 | 2008-10-16 | Angiotech Pharmaceuticals, Inc. | Self-retaining systems for surgical procedures |
| US8328841B2 (en) * | 2007-05-22 | 2012-12-11 | Cook Medical Technologies Llc | Embolization coil delivery systems and methods |
| WO2008151204A1 (en) | 2007-06-04 | 2008-12-11 | Sequent Medical Inc. | Methods and devices for treatment of vascular defects |
| US8100129B2 (en) * | 2007-08-28 | 2012-01-24 | Conceptus, Inc. | Methods and devices for occluding an ovarian pathway |
| ES2398779T3 (es) * | 2007-09-27 | 2013-03-21 | Ethicon Llc | Suturas de auto-retención que incluyen elementos de retención a tejido con resistencia mejorada |
| WO2009052432A2 (en) | 2007-10-19 | 2009-04-23 | Coherex Medical, Inc. | Medical device for modification of left atrial appendange and related systems and methods |
| US20090118709A1 (en) * | 2007-11-06 | 2009-05-07 | Vertos Medical, Inc. A Delaware Corporation | Tissue Excision Tool, Kits and Methods of Using the Same |
| WO2009073398A1 (en) * | 2007-12-03 | 2009-06-11 | Boston Scientific Scimed, Inc. | Implantable device with electrolytically detachable junction having multiple fine wires |
| JP5518737B2 (ja) | 2007-12-19 | 2014-06-11 | エシコン・エルエルシー | 熱接触媒介リテーナを備えた留置縫合糸 |
| US8916077B1 (en) | 2007-12-19 | 2014-12-23 | Ethicon, Inc. | Self-retaining sutures with retainers formed from molten material |
| US8118834B1 (en) | 2007-12-20 | 2012-02-21 | Angiotech Pharmaceuticals, Inc. | Composite self-retaining sutures and method |
| EP2234562B1 (en) | 2007-12-21 | 2019-02-27 | MicroVention, Inc. | A system and method of detecting implant detachment |
| WO2009082716A1 (en) * | 2007-12-21 | 2009-07-02 | Microvention, Inc. | System and method for locating detachment zone of a detachable implant |
| BRPI0821070B1 (pt) | 2007-12-21 | 2018-10-23 | Microvention Inc | dispositivo para implantação e método para a preparação de um filamento de hidrogel para implantação em um animal |
| US8615856B1 (en) | 2008-01-30 | 2013-12-31 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
| ES2602570T3 (es) | 2008-01-30 | 2017-02-21 | Ethicon Llc | Aparato y método para formar suturas de auto-retención |
| WO2009105663A2 (en) | 2008-02-21 | 2009-08-27 | Angiotech Pharmaceuticals, Inc. | Method and apparatus for elevating retainers on self-retaining sutures |
| US8641732B1 (en) | 2008-02-26 | 2014-02-04 | Ethicon, Inc. | Self-retaining suture with variable dimension filament and method |
| US20090227976A1 (en) * | 2008-03-05 | 2009-09-10 | Calabria Marie F | Multiple biocompatible polymeric strand aneurysm embolization system and method |
| CN101938943B (zh) * | 2008-03-31 | 2012-12-26 | 泰尔茂株式会社 | 医疗用闭塞装置 |
| US20100076463A1 (en) * | 2008-04-04 | 2010-03-25 | Akshay Mavani | Implantable fistula closure device |
| BRPI0911132B8 (pt) | 2008-04-15 | 2021-06-22 | Angiotech Pharm Inc | sutura para ser usada em um procedimento aplicado ao tecido |
| DK2265193T3 (da) | 2008-04-21 | 2012-01-23 | Nfocus Neuromedical Inc | Emboliske indretninger med flettet kugle og leveringssystemer |
| US10716573B2 (en) | 2008-05-01 | 2020-07-21 | Aneuclose | Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm |
| CN102083493A (zh) * | 2008-05-01 | 2011-06-01 | 安纽克罗斯有限责任公司 | 动脉瘤闭塞装置 |
| US10028747B2 (en) | 2008-05-01 | 2018-07-24 | Aneuclose Llc | Coils with a series of proximally-and-distally-connected loops for occluding a cerebral aneurysm |
| CN106974691A (zh) | 2008-05-02 | 2017-07-25 | 斯昆特医疗公司 | 用于治疗血管缺损的丝状装置 |
| US9675482B2 (en) | 2008-05-13 | 2017-06-13 | Covidien Lp | Braid implant delivery systems |
| US8961560B2 (en) | 2008-05-16 | 2015-02-24 | Ethicon, Inc. | Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods |
| AU2009282868B2 (en) | 2008-08-19 | 2013-09-05 | Covidien Lp | Detachable tip microcatheter |
| JP5787405B2 (ja) * | 2008-09-04 | 2015-09-30 | キュラシール インコーポレイテッド | 複数の腸内瘻孔処置用拡張可能デバイス |
| USD598549S1 (en) | 2008-09-16 | 2009-08-18 | Vertos Medical, Inc. | Surgical trocar |
| US9554826B2 (en) | 2008-10-03 | 2017-01-31 | Femasys, Inc. | Contrast agent injection system for sonographic imaging |
| US12171463B2 (en) | 2008-10-03 | 2024-12-24 | Femasys Inc. | Contrast agent generation and injection system for sonographic imaging |
| US10070888B2 (en) | 2008-10-03 | 2018-09-11 | Femasys, Inc. | Methods and devices for sonographic imaging |
| USD610259S1 (en) | 2008-10-23 | 2010-02-16 | Vertos Medical, Inc. | Tissue modification device |
| USD611146S1 (en) | 2008-10-23 | 2010-03-02 | Vertos Medical, Inc. | Tissue modification device |
| USD621939S1 (en) | 2008-10-23 | 2010-08-17 | Vertos Medical, Inc. | Tissue modification device |
| USD619253S1 (en) | 2008-10-23 | 2010-07-06 | Vertos Medical, Inc. | Tissue modification device |
| USD635671S1 (en) | 2008-10-23 | 2011-04-05 | Vertos Medical, Inc. | Tissue modification device |
| USD619252S1 (en) | 2008-10-23 | 2010-07-06 | Vertos Medical, Inc. | Tissue modification device |
| EP3420923A1 (en) | 2008-11-03 | 2019-01-02 | Ethicon, LLC | Length of self-retaining suture and device for using the same |
| US20100131002A1 (en) * | 2008-11-24 | 2010-05-27 | Connor Robert A | Stent with a net layer to embolize and aneurysm |
| US8795328B2 (en) | 2009-01-08 | 2014-08-05 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
| US9566419B2 (en) * | 2009-04-08 | 2017-02-14 | Bayer Healthcare Llc | Body lumen occlusion device and method |
| AU2010236337B2 (en) * | 2009-04-15 | 2015-01-29 | Microvention, Inc. | Implant delivery system |
| KR101828088B1 (ko) * | 2009-04-15 | 2018-02-09 | 마이크로벤션, 인코포레이티드 | 임플란트 전달 시스템 |
| EP2424775B1 (en) | 2009-04-30 | 2016-02-10 | Technip France | Spar mooring line sharing method and system |
| US10631969B2 (en) | 2009-06-17 | 2020-04-28 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
| US9351716B2 (en) | 2009-06-17 | 2016-05-31 | Coherex Medical, Inc. | Medical device and delivery system for modification of left atrial appendage and methods thereof |
| US10064628B2 (en) | 2009-06-17 | 2018-09-04 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
| US9649115B2 (en) | 2009-06-17 | 2017-05-16 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
| CA2958338C (en) | 2009-06-17 | 2019-04-16 | Coherex Medical, Inc. | Medical device for modification of left atrial appendage and related systems and methods |
| AU2010298026B2 (en) | 2009-09-24 | 2015-11-05 | Microvention, Inc. | Injectable hydrogel filaments for biomedical uses |
| US8434489B2 (en) | 2009-10-23 | 2013-05-07 | Conceptus, Inc. | Contraceptive devices and methods |
| WO2011053555A1 (en) * | 2009-10-26 | 2011-05-05 | Microvention, Inc. | Embolization device constructed from expansile polymer |
| WO2011057002A2 (en) | 2009-11-05 | 2011-05-12 | Sequent Medical Inc. | Multiple layer filamentary devices or treatment of vascular defects |
| WO2011057131A1 (en) | 2009-11-09 | 2011-05-12 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
| JP2013509963A (ja) | 2009-11-09 | 2013-03-21 | スポットライト テクノロジー パートナーズ エルエルシー | 断片化ヒドロゲル |
| US9358140B1 (en) | 2009-11-18 | 2016-06-07 | Aneuclose Llc | Stent with outer member to embolize an aneurysm |
| US8906057B2 (en) * | 2010-01-04 | 2014-12-09 | Aneuclose Llc | Aneurysm embolization by rotational accumulation of mass |
| US8231619B2 (en) | 2010-01-22 | 2012-07-31 | Cytyc Corporation | Sterilization device and method |
| WO2011110177A1 (en) * | 2010-03-09 | 2011-09-15 | Lina Medical Aps | Contraceptive device |
| JP5899200B2 (ja) | 2010-04-14 | 2016-04-06 | マイクロベンション インコーポレイテッド | インプラント送達デバイス |
| US8550086B2 (en) | 2010-05-04 | 2013-10-08 | Hologic, Inc. | Radiopaque implant |
| US20130180966A1 (en) | 2010-05-04 | 2013-07-18 | Jeffrey M. Gross | Laser cutting system and methods for creating self-retaining sutures |
| CN103068323B (zh) | 2010-06-11 | 2015-07-22 | 伊西康有限责任公司 | 用于内窥镜式和机器人辅助式外科手术的缝合线递送工具 |
| US9220506B2 (en) | 2010-06-16 | 2015-12-29 | DePuy Synthes Products, Inc. | Occlusive device with stretch resistant member and anchor filament |
| US9247942B2 (en) | 2010-06-29 | 2016-02-02 | Artventive Medical Group, Inc. | Reversible tubal contraceptive device |
| US9017351B2 (en) | 2010-06-29 | 2015-04-28 | Artventive Medical Group, Inc. | Reducing flow through a tubular structure |
| US8425548B2 (en) | 2010-07-01 | 2013-04-23 | Aneaclose LLC | Occluding member expansion and then stent expansion for aneurysm treatment |
| US9149277B2 (en) | 2010-10-18 | 2015-10-06 | Artventive Medical Group, Inc. | Expandable device delivery |
| KR20130140762A (ko) | 2010-11-03 | 2013-12-24 | 에티컨, 엘엘씨 | 약물-용출 자가-유지형 봉합재 및 그 관련 방법 |
| BR112013011582B1 (pt) | 2010-11-09 | 2020-10-20 | Ethicon Llc | sistema de autorretenção multidirecional removível |
| US8360765B2 (en) | 2011-01-07 | 2013-01-29 | Covidien Lp | Systems and method for forming a coaxial implant |
| EP2688490B1 (en) | 2011-03-23 | 2017-02-01 | Ethicon, LLC | Self-retaining variable loop sutures |
| US20120253381A1 (en) | 2011-03-31 | 2012-10-04 | Codman & Shurtleff, Inc. | Occlusive device with porous structure and stretch resistant member |
| US9456823B2 (en) | 2011-04-18 | 2016-10-04 | Terumo Corporation | Embolic devices |
| US20120283768A1 (en) * | 2011-05-05 | 2012-11-08 | Sequent Medical Inc. | Method and apparatus for the treatment of large and giant vascular defects |
| WO2012155093A1 (en) | 2011-05-11 | 2012-11-15 | Microvention, Inc. | Device for occluding a lumen |
| US9138232B2 (en) | 2011-05-24 | 2015-09-22 | Aneuclose Llc | Aneurysm occlusion by rotational dispensation of mass |
| US20130172931A1 (en) | 2011-06-06 | 2013-07-04 | Jeffrey M. Gross | Methods and devices for soft palate tissue elevation procedures |
| JP6122424B2 (ja) | 2011-06-16 | 2017-04-26 | キュラシール インコーポレイテッド | 瘻孔処置用デバイス及びその関連方法 |
| EP2720623A4 (en) | 2011-06-17 | 2015-04-22 | Curaseal Inc | METHOD AND DEVICES FOR TREATING FISTLES |
| EP2773270B1 (en) | 2011-11-01 | 2020-02-26 | Coherex Medical, Inc. | Medical device system for modification of left atrial appendage |
| US9579104B2 (en) | 2011-11-30 | 2017-02-28 | Covidien Lp | Positioning and detaching implants |
| US8758427B2 (en) | 2011-12-02 | 2014-06-24 | Vascular Solutions, Inc. | Elongated expandable member for occluding varicose veins |
| US9011480B2 (en) | 2012-01-20 | 2015-04-21 | Covidien Lp | Aneurysm treatment coils |
| WO2013119332A2 (en) | 2012-02-09 | 2013-08-15 | Stout Medical Group, L.P. | Embolic device and methods of use |
| US9687245B2 (en) | 2012-03-23 | 2017-06-27 | Covidien Lp | Occlusive devices and methods of use |
| WO2013158781A1 (en) | 2012-04-18 | 2013-10-24 | Microvention, Inc. | Embolic devices |
| EP2674114A1 (en) | 2012-06-11 | 2013-12-18 | Acandis GmbH & Co. KG | Implant for occlusion of vascular anomalies and method for producing such an implant |
| US10124087B2 (en) | 2012-06-19 | 2018-11-13 | Covidien Lp | Detachable coupling for catheter |
| US9326774B2 (en) | 2012-08-03 | 2016-05-03 | Covidien Lp | Device for implantation of medical devices |
| KR20150084959A (ko) | 2012-11-13 | 2015-07-22 | 코비디엔 엘피 | 폐색 장치 |
| US10342546B2 (en) | 2013-01-14 | 2019-07-09 | Microvention, Inc. | Occlusive device |
| US8984733B2 (en) | 2013-02-05 | 2015-03-24 | Artventive Medical Group, Inc. | Bodily lumen occlusion |
| US9095344B2 (en) | 2013-02-05 | 2015-08-04 | Artventive Medical Group, Inc. | Methods and apparatuses for blood vessel occlusion |
| US9662119B2 (en) * | 2013-03-13 | 2017-05-30 | Lawrence Livermore National Security, Llc | Shape-memory polymer foam device for treating aneurysms |
| WO2014178869A1 (en) * | 2013-05-02 | 2014-11-06 | Empire Technology Development Llc | Diverticulum treating device |
| US9737308B2 (en) | 2013-06-14 | 2017-08-22 | Artventive Medical Group, Inc. | Catheter-assisted tumor treatment |
| US10149968B2 (en) | 2013-06-14 | 2018-12-11 | Artventive Medical Group, Inc. | Catheter-assisted tumor treatment |
| US9737306B2 (en) | 2013-06-14 | 2017-08-22 | Artventive Medical Group, Inc. | Implantable luminal devices |
| US9636116B2 (en) | 2013-06-14 | 2017-05-02 | Artventive Medical Group, Inc. | Implantable luminal devices |
| US9681876B2 (en) | 2013-07-31 | 2017-06-20 | EMBA Medical Limited | Methods and devices for endovascular embolization |
| US10010328B2 (en) | 2013-07-31 | 2018-07-03 | NeuVT Limited | Endovascular occlusion device with hemodynamically enhanced sealing and anchoring |
| US9078658B2 (en) | 2013-08-16 | 2015-07-14 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
| US9955976B2 (en) | 2013-08-16 | 2018-05-01 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
| ES2711753T3 (es) | 2014-02-27 | 2019-05-07 | Incumedx Inc | Microbobinas de armazón embólicas |
| US10124090B2 (en) | 2014-04-03 | 2018-11-13 | Terumo Corporation | Embolic devices |
| US9629635B2 (en) | 2014-04-14 | 2017-04-25 | Sequent Medical, Inc. | Devices for therapeutic vascular procedures |
| US9713475B2 (en) | 2014-04-18 | 2017-07-25 | Covidien Lp | Embolic medical devices |
| US10092663B2 (en) | 2014-04-29 | 2018-10-09 | Terumo Corporation | Polymers |
| WO2015167752A1 (en) | 2014-04-29 | 2015-11-05 | Microvention, Inc. | Polymers including active agents |
| US10363043B2 (en) | 2014-05-01 | 2019-07-30 | Artventive Medical Group, Inc. | Treatment of incompetent vessels |
| US9060777B1 (en) | 2014-05-28 | 2015-06-23 | Tw Medical Technologies, Llc | Vaso-occlusive devices and methods of use |
| EP3148481A4 (en) | 2014-05-28 | 2017-05-03 | Stryker European Holdings I, LLC | Vaso-occlusive devices and methods of use |
| US10136897B2 (en) * | 2014-07-22 | 2018-11-27 | Boston Scientific Scimed, Inc. | Expandable vaso-occlusive devices having shape memory and methods of using the same |
| US9808256B2 (en) | 2014-08-08 | 2017-11-07 | Covidien Lp | Electrolytic detachment elements for implant delivery systems |
| US9814466B2 (en) | 2014-08-08 | 2017-11-14 | Covidien Lp | Electrolytic and mechanical detachment for implant delivery systems |
| CN104188733B (zh) * | 2014-08-11 | 2016-07-06 | 中国人民解放军总医院 | 用于形成血管栓塞的装置、系统及其用途 |
| CN104398283A (zh) * | 2014-09-15 | 2015-03-11 | 北京泰杰伟业科技有限公司 | 一种带有可膨胀聚合物的栓塞器械 |
| TW201625754A (zh) * | 2014-11-21 | 2016-07-16 | 艾倫塔斯有限公司 | 單一成份、儲存穩定、可硬化之聚矽氧組成物 |
| WO2016118420A1 (en) | 2015-01-20 | 2016-07-28 | Neurogami Medical, Inc. | Micrograft for the treatment of intracranial aneurysms and method for use |
| US10736730B2 (en) | 2015-01-20 | 2020-08-11 | Neurogami Medical, Inc. | Vascular implant |
| US10857012B2 (en) | 2015-01-20 | 2020-12-08 | Neurogami Medical, Inc. | Vascular implant |
| US10925611B2 (en) | 2015-01-20 | 2021-02-23 | Neurogami Medical, Inc. | Packaging for surgical implant |
| US11484319B2 (en) | 2015-01-20 | 2022-11-01 | Neurogami Medical, Inc. | Delivery system for micrograft for treating intracranial aneurysms |
| US20160278785A1 (en) * | 2015-03-26 | 2016-09-29 | Boston Scientific Scimed, Inc. | Biologic-based expandable occlusion devices |
| US9943314B2 (en) | 2015-04-14 | 2018-04-17 | Teleflex Innovations S.À.R.L. | Magnetically-driven delivery assembly and method |
| US10159490B2 (en) | 2015-05-08 | 2018-12-25 | Stryker European Holdings I, Llc | Vaso-occlusive devices |
| US9717503B2 (en) | 2015-05-11 | 2017-08-01 | Covidien Lp | Electrolytic detachment for implant delivery systems |
| WO2016201250A1 (en) | 2015-06-11 | 2016-12-15 | Microvention, Inc. | Expansile device for implantation |
| US10716915B2 (en) * | 2015-11-23 | 2020-07-21 | Mivi Neuroscience, Inc. | Catheter systems for applying effective suction in remote vessels and thrombectomy procedures facilitated by catheter systems |
| US10813644B2 (en) | 2016-04-01 | 2020-10-27 | Artventive Medical Group, Inc. | Occlusive implant and delivery system |
| JP6418613B2 (ja) * | 2016-05-31 | 2018-11-07 | 国立大学法人信州大学 | 塞栓コイル |
| US10828039B2 (en) | 2016-06-27 | 2020-11-10 | Covidien Lp | Electrolytic detachment for implantable devices |
| US10828037B2 (en) | 2016-06-27 | 2020-11-10 | Covidien Lp | Electrolytic detachment with fluid electrical connection |
| US11051822B2 (en) | 2016-06-28 | 2021-07-06 | Covidien Lp | Implant detachment with thermal activation |
| US10420563B2 (en) | 2016-07-08 | 2019-09-24 | Neurogami Medical, Inc. | Delivery system insertable through body lumen |
| US10595981B2 (en) * | 2016-08-16 | 2020-03-24 | Medtronic Vascular, Inc. | Coated sutures for reducing stent graft endoleaks |
| EP3881780B1 (en) | 2016-09-07 | 2023-11-01 | Vertos Medical, Inc. | Trephine for percutaneous lateral recess resection. |
| US10842607B2 (en) | 2016-10-14 | 2020-11-24 | Microvention, Inc. | Embolic coils |
| US10576099B2 (en) * | 2016-10-21 | 2020-03-03 | Covidien Lp | Injectable scaffold for treatment of intracranial aneurysms and related technology |
| EP3614933A1 (en) | 2017-04-27 | 2020-03-04 | Boston Scientific Scimed, Inc. | Occlusive medical device with fabric retention barb |
| IT201800002332A1 (it) * | 2018-02-02 | 2019-08-02 | Amista Pietro | Dispositivo intraneurismatico per il trattamento di aneurismi |
| ES3035267T3 (en) * | 2018-04-04 | 2025-09-01 | Incumedx Inc | Embolic device with improved neck coverage |
| DE102018113580A1 (de) * | 2018-06-07 | 2019-12-12 | Christoph Karl | Verfahren und vorrichtung zur herstellung eines implantats |
| US11596533B2 (en) | 2018-08-21 | 2023-03-07 | Boston Scientific Scimed, Inc. | Projecting member with barb for cardiovascular devices |
| US12114863B2 (en) | 2018-12-05 | 2024-10-15 | Microvention, Inc. | Implant delivery system |
| US11559309B2 (en) | 2019-03-15 | 2023-01-24 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
| US11291453B2 (en) | 2019-03-15 | 2022-04-05 | Sequent Medical, Inc. | Filamentary devices having a flexible joint for treatment of vascular defects |
| WO2020190639A1 (en) | 2019-03-15 | 2020-09-24 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
| US11369355B2 (en) | 2019-06-17 | 2022-06-28 | Coherex Medical, Inc. | Medical device and system for occluding a tissue opening and method thereof |
| WO2021011694A1 (en) | 2019-07-17 | 2021-01-21 | Boston Scientific Scimed, Inc. | Left atrial appendage implant with continuous covering |
| US11540838B2 (en) | 2019-08-30 | 2023-01-03 | Boston Scientific Scimed, Inc. | Left atrial appendage implant with sealing disk |
| US11484629B2 (en) | 2019-09-11 | 2022-11-01 | Stryker Corporation | Intravascular devices with high tungsten content |
| US11612678B2 (en) | 2019-09-11 | 2023-03-28 | Stryker Corporation | Intravascular devices |
| US11504816B2 (en) | 2019-11-04 | 2022-11-22 | Covidien Lp | Systems and methods for treating aneurysms |
| US12023034B2 (en) | 2020-03-11 | 2024-07-02 | Microvention, Inc. | Devices for treatment of vascular defects |
| US12070220B2 (en) | 2020-03-11 | 2024-08-27 | Microvention, Inc. | Devices having multiple permeable shells for treatment of vascular defects |
| US20210282789A1 (en) | 2020-03-11 | 2021-09-16 | Microvention, Inc. | Multiple layer devices for treatment of vascular defects |
| US11903589B2 (en) | 2020-03-24 | 2024-02-20 | Boston Scientific Scimed, Inc. | Medical system for treating a left atrial appendage |
| WO2022115690A1 (en) | 2020-11-30 | 2022-06-02 | Boston Scientific Scimed, Inc. | Implantable passive mean pressure sensor |
| US11812969B2 (en) | 2020-12-03 | 2023-11-14 | Coherex Medical, Inc. | Medical device and system for occluding a tissue opening and method thereof |
| EP4277545A1 (en) | 2021-01-14 | 2023-11-22 | Boston Scientific Scimed, Inc. | Medical system for treating a left atrial appendage |
| US12383201B2 (en) | 2021-02-03 | 2025-08-12 | Boston Scientific Scimed, Inc. | Medical system for treating a left atrial appendage |
| EP4358872A1 (en) | 2021-06-22 | 2024-05-01 | Boston Scientific Scimed, Inc. | Left atrial appendage implant |
| JP7690067B2 (ja) | 2021-07-08 | 2025-06-09 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 左心耳閉鎖デバイス |
| US12446891B2 (en) | 2021-08-30 | 2025-10-21 | Microvention, Inc. | Devices for treatment of vascular defects |
| WO2023038929A1 (en) | 2021-09-08 | 2023-03-16 | Boston Scientific Scimed, Inc. | Occlusive implant with multi-sharpness split tip soft tissue anchors |
| JP2025520556A (ja) | 2022-06-16 | 2025-07-03 | ヴェルトス・メディカル，インコーポレイテッド | 一体型器具アセンブリ |
| US20240016497A1 (en) * | 2022-07-12 | 2024-01-18 | Medtronic Inc. | Implantable embolization device |
| WO2025122700A1 (en) * | 2023-12-05 | 2025-06-12 | The Regents Of The University Of California | System and method for minimally invasive tubal sterilization |
| US20250204923A1 (en) * | 2023-12-20 | 2025-06-26 | Boston Scientific Scimed, Inc. | Left atrial appendage implant |
Family Cites Families (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS154391B1 (enExample) * | 1970-09-10 | 1974-04-30 | ||
| US4509504A (en) * | 1978-01-18 | 1985-04-09 | Medline Ab | Occlusion of body channels |
| US4301803A (en) * | 1978-10-06 | 1981-11-24 | Kuraray Co., Ltd. | Balloon catheter |
| US4346712A (en) * | 1979-04-06 | 1982-08-31 | Kuraray Company, Ltd. | Releasable balloon catheter |
| SE419597B (sv) * | 1979-05-04 | 1981-08-17 | Medline Ab | Anordning for temporer eller permanent tillslutning av kroppskanaler eller halrum hos menniskor och djur |
| SE447446B (sv) * | 1979-12-05 | 1986-11-17 | Medline Ab | Anordning for tillforande av medicinskt aktiva substanser for att fremja en abort |
| HU184722B (en) | 1980-02-18 | 1984-10-29 | Laszlo Lazar | Therapeutically suitable silicone rubber mixture and therapeuticaid |
| US4529739A (en) * | 1984-07-24 | 1985-07-16 | The Dow Chemical Company | Foamed polymeric materials |
| JPH0678460B2 (ja) * | 1985-05-01 | 1994-10-05 | 株式会社バイオマテリアル・ユニバース | 多孔質透明ポリビニルアルユールゲル |
| US4795741A (en) | 1987-05-06 | 1989-01-03 | Biomatrix, Inc. | Compositions for therapeutic percutaneous embolization and the use thereof |
| US4819637A (en) | 1987-09-01 | 1989-04-11 | Interventional Therapeutics Corporation | System for artificial vessel embolization and devices for use therewith |
| US4994069A (en) | 1988-11-02 | 1991-02-19 | Target Therapeutics | Vaso-occlusion coil and method |
| US5354290A (en) * | 1989-05-31 | 1994-10-11 | Kimberly-Clark Corporation | Porous structure of an absorbent polymer |
| US5122136A (en) | 1990-03-13 | 1992-06-16 | The Regents Of The University Of California | Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US5133731A (en) | 1990-11-09 | 1992-07-28 | Catheter Research, Inc. | Embolus supply system and method |
| US5129180A (en) * | 1990-12-07 | 1992-07-14 | Landec Labs, Inc. | Temperature sensitive seed germination control |
| US5120349A (en) | 1990-12-07 | 1992-06-09 | Landec Labs, Inc. | Microcapsule having temperature-dependent permeability profile |
| DE4104702C2 (de) * | 1991-02-15 | 1996-01-18 | Malte Neuss | Implantate für Organwege in Wendelform |
| US5304194A (en) * | 1991-10-02 | 1994-04-19 | Target Therapeutics | Vasoocclusion coil with attached fibrous element(s) |
| US5226911A (en) | 1991-10-02 | 1993-07-13 | Target Therapeutics | Vasoocclusion coil with attached fibrous element(s) |
| JP3356447B2 (ja) * | 1991-10-16 | 2002-12-16 | テルモ株式会社 | 乾燥高分子ゲルからなる血管病変塞栓材料 |
| US5258042A (en) | 1991-12-16 | 1993-11-02 | Henry Ford Health System | Intravascular hydrogel implant |
| DK0625070T3 (da) * | 1991-12-20 | 1999-02-22 | Allied Signal Inc | Materialer med lav massefylde, som har høje overfladearealer, og genstande dannet derudfra til anvendelse ved genvindingen |
| WO1994006460A1 (en) | 1992-09-21 | 1994-03-31 | Vitaphore Corporation | Embolization plugs for blood vessels |
| US5312415A (en) * | 1992-09-22 | 1994-05-17 | Target Therapeutics, Inc. | Assembly for placement of embolic coils using frictional placement |
| US5350397A (en) * | 1992-11-13 | 1994-09-27 | Target Therapeutics, Inc. | Axially detachable embolic coil assembly |
| US5250071A (en) * | 1992-09-22 | 1993-10-05 | Target Therapeutics, Inc. | Detachable embolic coil assembly using interlocking clasps and method of use |
| US5382259A (en) | 1992-10-26 | 1995-01-17 | Target Therapeutics, Inc. | Vasoocclusion coil with attached tubular woven or braided fibrous covering |
| US5382260A (en) * | 1992-10-30 | 1995-01-17 | Interventional Therapeutics Corp. | Embolization device and apparatus including an introducer cartridge and method for delivering the same |
| US5690666A (en) | 1992-11-18 | 1997-11-25 | Target Therapeutics, Inc. | Ultrasoft embolism coils and process for using them |
| US5320639A (en) * | 1993-03-12 | 1994-06-14 | Meadox Medicals, Inc. | Vascular plug delivery system |
| JPH09510637A (ja) * | 1994-03-18 | 1997-10-28 | クック インコーポレイティッド | 螺旋状塞栓形成コイル |
| JPH09512111A (ja) * | 1994-04-18 | 1997-12-02 | ゾイフェルト、ハインツ | 背面映写モジュール |
| US5939622A (en) | 1994-04-26 | 1999-08-17 | Cytec Technology Corp. | Settling process analysis method |
| US5573994A (en) * | 1994-05-13 | 1996-11-12 | University Of Cincinnati | Superabsorbent foams, and method for producing the same |
| JP2535785B2 (ja) | 1994-06-03 | 1996-09-18 | 工業技術院長 | 血管塞栓剤 |
| US5549624A (en) * | 1994-06-24 | 1996-08-27 | Target Therapeutics, Inc. | Fibered vasooclusion coils |
| JPH10504210A (ja) * | 1994-08-17 | 1998-04-28 | ボストン サイエンティフィック コーポレイション | インプラント、移植方法、及び適用装置 |
| US5570585A (en) | 1994-10-03 | 1996-11-05 | Vaynberg; Mikhail | Universal cooling system automatically configured to operate in compound or single compressor mode |
| US5690671A (en) | 1994-12-13 | 1997-11-25 | Micro Interventional Systems, Inc. | Embolic elements and methods and apparatus for their delivery |
| US5578074A (en) | 1994-12-22 | 1996-11-26 | Target Therapeutics, Inc. | Implant delivery method and assembly |
| WO1996022736A1 (en) * | 1995-01-27 | 1996-08-01 | Scimed Life Systems, Inc. | Embolizing system |
| US5750585A (en) | 1995-04-04 | 1998-05-12 | Purdue Research Foundation | Super absorbent hydrogel foams |
| US5911731A (en) * | 1995-04-20 | 1999-06-15 | Target Therapeutics, Inc. | Anatomically shaped vasoocclusive devices |
| US5645558A (en) * | 1995-04-20 | 1997-07-08 | Medical University Of South Carolina | Anatomically shaped vasoocclusive device and method of making the same |
| US6143007A (en) * | 1995-04-28 | 2000-11-07 | Target Therapeutics, Inc. | Method for making an occlusive device |
| US5766160A (en) * | 1995-06-06 | 1998-06-16 | Target Therapeutics, Inc. | Variable stiffness coils |
| US6103084A (en) | 1995-06-06 | 2000-08-15 | Eppendorf Netheler-Hinz Gmbh | Apparatus for electroporation |
| US5624461A (en) * | 1995-06-06 | 1997-04-29 | Target Therapeutics, Inc. | Three dimensional in-filling vaso-occlusive coils |
| US6013084A (en) * | 1995-06-30 | 2000-01-11 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils (II) |
| US5853418A (en) * | 1995-06-30 | 1998-12-29 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils (II) |
| US5582619A (en) | 1995-06-30 | 1996-12-10 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils |
| NO962761L (no) * | 1995-06-30 | 1997-01-02 | Target Therapeutics Inc | Strekkmotstandige vasookklusive spiraler |
| US5580568A (en) | 1995-07-27 | 1996-12-03 | Micro Therapeutics, Inc. | Cellulose diacetate compositions for use in embolizing blood vessels |
| CA2228118A1 (en) | 1995-07-28 | 1997-02-13 | Focal, Inc. | Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatments agents |
| DE29518932U1 (de) | 1995-11-29 | 1996-06-20 | Reul, Jürgen, Dr.med., 52146 Würselen | Kontrolliert ablösbare Embolisations-Kugelspirale |
| AU690862B2 (en) * | 1995-12-04 | 1998-04-30 | Target Therapeutics, Inc. | Fibered micro vaso-occlusive devices |
| US5658308A (en) | 1995-12-04 | 1997-08-19 | Target Therapeutics, Inc. | Bioactive occlusion coil |
| US5752974A (en) * | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
| US5749894A (en) * | 1996-01-18 | 1998-05-12 | Target Therapeutics, Inc. | Aneurysm closure method |
| US5898411A (en) * | 1996-02-26 | 1999-04-27 | Pacific Antenna Technologies, Inc. | Single-element, multi-frequency, dipole antenna |
| US5792154A (en) * | 1996-04-10 | 1998-08-11 | Target Therapeutics, Inc. | Soft-ended fibered micro vaso-occlusive devices |
| US6190402B1 (en) | 1996-06-21 | 2001-02-20 | Musc Foundation For Research Development | Insitu formable and self-forming intravascular flow modifier (IFM) and IFM assembly for deployment of same |
| US5980514A (en) * | 1996-07-26 | 1999-11-09 | Target Therapeutics, Inc. | Aneurysm closure device assembly |
| US5695480A (en) * | 1996-07-29 | 1997-12-09 | Micro Therapeutics, Inc. | Embolizing compositions |
| US5823198A (en) | 1996-07-31 | 1998-10-20 | Micro Therapeutics, Inc. | Method and apparatus for intravasculer embolization |
| US5690667A (en) * | 1996-09-26 | 1997-11-25 | Target Therapeutics | Vasoocclusion coil having a polymer tip |
| GB9704288D0 (en) | 1997-03-01 | 1997-04-23 | Smith & Nephew | Hydrogels |
| US5911717A (en) * | 1997-03-17 | 1999-06-15 | Precision Vascular Systems, Inc. | Catheter deliverable thrombogenic apparatus and method |
| US5980554A (en) * | 1997-05-05 | 1999-11-09 | Micro Therapeutics, Inc. | Wire frame partial flow obstruction for aneurysm treatment |
| US6271278B1 (en) * | 1997-05-13 | 2001-08-07 | Purdue Research Foundation | Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties |
| US5891192A (en) * | 1997-05-22 | 1999-04-06 | The Regents Of The University Of California | Ion-implanted protein-coated intralumenal implants |
| US5916235A (en) * | 1997-08-13 | 1999-06-29 | The Regents Of The University Of California | Apparatus and method for the use of detachable coils in vascular aneurysms and body cavities |
| US6316522B1 (en) | 1997-08-18 | 2001-11-13 | Scimed Life Systems, Inc. | Bioresorbable hydrogel compositions for implantable prostheses |
| JP2001522629A (ja) | 1997-11-07 | 2001-11-20 | サルヴィアック・リミテッド | 医学用の挿入可能な閉塞器具 |
| US6168570B1 (en) * | 1997-12-05 | 2001-01-02 | Micrus Corporation | Micro-strand cable with enhanced radiopacity |
| US5935145A (en) * | 1998-02-13 | 1999-08-10 | Target Therapeutics, Inc. | Vaso-occlusive device with attached polymeric materials |
| US6015424A (en) * | 1998-04-28 | 2000-01-18 | Microvention, Inc. | Apparatus and method for vascular embolization |
| US6113629A (en) | 1998-05-01 | 2000-09-05 | Micrus Corporation | Hydrogel for the therapeutic treatment of aneurysms |
| US6463317B1 (en) | 1998-05-19 | 2002-10-08 | Regents Of The University Of Minnesota | Device and method for the endovascular treatment of aneurysms |
| US5980550A (en) | 1998-06-18 | 1999-11-09 | Target Therapeutics, Inc. | Water-soluble coating for bioactive vasoocclusive devices |
| US5935148A (en) * | 1998-06-24 | 1999-08-10 | Target Therapeutics, Inc. | Detachable, varying flexibility, aneurysm neck bridge |
| US6165193A (en) * | 1998-07-06 | 2000-12-26 | Microvention, Inc. | Vascular embolization with an expansible implant |
| US6093199A (en) * | 1998-08-05 | 2000-07-25 | Endovascular Technologies, Inc. | Intra-luminal device for treatment of body cavities and lumens and method of use |
| US6605294B2 (en) * | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
| US6187024B1 (en) * | 1998-11-10 | 2001-02-13 | Target Therapeutics, Inc. | Bioactive coating for vaso-occlusive devices |
| US6280457B1 (en) * | 1999-06-04 | 2001-08-28 | Scimed Life Systems, Inc. | Polymer covered vaso-occlusive devices and methods of producing such devices |
| US6312421B1 (en) | 1999-07-23 | 2001-11-06 | Neurovasx, Inc. | Aneurysm embolization material and device |
| WO2001028434A1 (en) * | 1999-10-04 | 2001-04-26 | Microvention, Inc. | Filamentous embolic device with expansible elements |
| US6238403B1 (en) * | 1999-10-04 | 2001-05-29 | Microvention, Inc. | Filamentous embolic device with expansible elements |
| EP1104681A1 (en) | 1999-12-03 | 2001-06-06 | Biomat B.V. | Wire, tube or catheter with hydrophilic coating |
| US6530934B1 (en) * | 2000-06-06 | 2003-03-11 | Sarcos Lc | Embolic device composed of a linear sequence of miniature beads |
| WO2002005731A1 (en) | 2000-07-18 | 2002-01-24 | Teitelbaum George P | Biocompatible, expansile material and stent |
| US6723108B1 (en) | 2000-09-18 | 2004-04-20 | Cordis Neurovascular, Inc | Foam matrix embolization device |
-
2002
- 2002-05-29 JP JP2002592820A patent/JP4383746B2/ja not_active Expired - Fee Related
- 2002-05-29 CA CA2689598A patent/CA2689598A1/en not_active Abandoned
- 2002-05-29 US US10/157,621 patent/US7014645B2/en not_active Expired - Lifetime
- 2002-05-29 AT AT02752008T patent/ATE516759T1/de not_active IP Right Cessation
- 2002-05-29 AU AU2002344223A patent/AU2002344223B2/en not_active Ceased
- 2002-05-29 EP EP10183747.4A patent/EP2319430B1/en not_active Expired - Lifetime
- 2002-05-29 EP EP02752008A patent/EP1401338B1/en not_active Expired - Lifetime
- 2002-05-29 ES ES10183747.4T patent/ES2441341T3/es not_active Expired - Lifetime
- 2002-05-29 CA CA002449055A patent/CA2449055C/en not_active Expired - Fee Related
- 2002-05-29 WO PCT/US2002/016873 patent/WO2002096302A1/en not_active Ceased
-
2003
- 2003-09-24 US US10/670,142 patent/US7491214B2/en not_active Expired - Fee Related
-
2006
- 2006-02-08 US US11/350,357 patent/US7842054B2/en not_active Expired - Lifetime
- 2006-10-06 AU AU2006225285A patent/AU2006225285B2/en not_active Ceased
-
2009
- 2009-01-29 US US12/362,466 patent/US8603128B2/en not_active Expired - Lifetime
-
2010
- 2010-01-15 AU AU2010200166A patent/AU2010200166A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006225285B2 (en) | 2009-10-29 |
| US8603128B2 (en) | 2013-12-10 |
| AU2010200166A1 (en) | 2010-02-04 |
| US7491214B2 (en) | 2009-02-17 |
| EP2319430A3 (en) | 2011-09-28 |
| US7842054B2 (en) | 2010-11-30 |
| US7014645B2 (en) | 2006-03-21 |
| ATE516759T1 (de) | 2011-08-15 |
| US20020177855A1 (en) | 2002-11-28 |
| EP1401338A1 (en) | 2004-03-31 |
| EP1401338B1 (en) | 2011-07-20 |
| CA2449055A1 (en) | 2002-12-05 |
| US20060149299A1 (en) | 2006-07-06 |
| US20040059370A1 (en) | 2004-03-25 |
| JP2004527342A (ja) | 2004-09-09 |
| JP4383746B2 (ja) | 2009-12-16 |
| WO2002096302A1 (en) | 2002-12-05 |
| US20090232869A1 (en) | 2009-09-17 |
| EP2319430A2 (en) | 2011-05-11 |
| EP2319430B1 (en) | 2013-11-13 |
| AU2006225285A1 (en) | 2006-10-26 |
| AU2002344223C1 (en) | 2002-12-09 |
| CA2449055C (en) | 2010-03-02 |
| AU2002344223B2 (en) | 2006-07-06 |
| ES2441341T3 (es) | 2014-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2449055C (en) | Method of manufacturing expansile filamentous embolization devices | |
| AU2002344223A1 (en) | Method of Manufacturing Expansile Filamentous Embolization Devices | |
| US6602261B2 (en) | Filamentous embolic device with expansile elements | |
| AU2008207620B2 (en) | Filamentous embolic device with expansible elements | |
| CA2385615C (en) | Filamentous embolic device with expansible elements | |
| CA2777171C (en) | Embolization device constructed from expansile polymer | |
| AU754493B2 (en) | Expansible implant for vascular embolization and method of making the same | |
| ES2369882T3 (es) | Procedimiento de fabricación de dispositivos para embolización filamentosos expansibles. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |