CA2689024C - High sensitivity immunoassays and kits for the determination of peptidesand proteins of biological interest - Google Patents

High sensitivity immunoassays and kits for the determination of peptidesand proteins of biological interest Download PDF

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Publication number
CA2689024C
CA2689024C CA2689024A CA2689024A CA2689024C CA 2689024 C CA2689024 C CA 2689024C CA 2689024 A CA2689024 A CA 2689024A CA 2689024 A CA2689024 A CA 2689024A CA 2689024 C CA2689024 C CA 2689024C
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CA
Canada
Prior art keywords
antibody
beta
kit
peptide
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2689024A
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English (en)
French (fr)
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CA2689024A1 (en
Inventor
J Manuel Sarasa Barrio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Araclon Biotech SL
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Araclon Biotech SL
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38544110&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2689024(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Araclon Biotech SL filed Critical Araclon Biotech SL
Publication of CA2689024A1 publication Critical patent/CA2689024A1/en
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Publication of CA2689024C publication Critical patent/CA2689024C/en
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2689024A 2007-08-02 2007-12-05 High sensitivity immunoassays and kits for the determination of peptidesand proteins of biological interest Active CA2689024C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07380227.4 2007-08-02
EP07380227A EP2020602A1 (en) 2007-08-02 2007-08-02 High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest
PCT/EP2007/063334 WO2009015696A1 (en) 2007-08-02 2007-12-05 High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest

Publications (2)

Publication Number Publication Date
CA2689024A1 CA2689024A1 (en) 2009-02-05
CA2689024C true CA2689024C (en) 2015-02-24

Family

ID=38544110

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2689024A Active CA2689024C (en) 2007-08-02 2007-12-05 High sensitivity immunoassays and kits for the determination of peptidesand proteins of biological interest

Country Status (23)

Country Link
US (2) US20090035790A1 (ko)
EP (2) EP2020602A1 (ko)
JP (1) JP5657382B2 (ko)
KR (1) KR101461538B1 (ko)
CN (1) CN101861521B (ko)
AR (1) AR064186A1 (ko)
AT (1) ATE533059T1 (ko)
AU (1) AU2007357025B2 (ko)
BR (1) BRPI0721871A2 (ko)
CA (1) CA2689024C (ko)
CL (1) CL2007003513A1 (ko)
CY (1) CY1112553T1 (ko)
DK (1) DK2183599T3 (ko)
ES (1) ES2377151T3 (ko)
HR (1) HRP20120020T1 (ko)
IL (1) IL202598A (ko)
MX (1) MX2009013009A (ko)
PL (1) PL2183599T3 (ko)
PT (1) PT2183599E (ko)
RS (1) RS52124B (ko)
RU (1) RU2461837C2 (ko)
SI (1) SI2183599T1 (ko)
WO (1) WO2009015696A1 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG179095A1 (en) 2009-09-18 2012-04-27 Probiodrug Ag Novel assay for the detection of amyloid beta peptides
PT2510359E (pt) * 2009-12-11 2015-12-02 Araclón Biotech S L Métodos e reagentes para a deteção melhorada de péptidos beta-amiloides
CN102192985A (zh) * 2010-03-18 2011-09-21 上海依科赛生物制品有限公司 一种人体β淀粉样蛋白试剂盒
KR101352670B1 (ko) * 2010-06-15 2014-01-17 울산대학교 산학협력단 알츠하이머 전구단백질 분비 펩타이드의 축적물을 포함하는 뇌 노화 감별 진단 마커
US20120141985A1 (en) * 2010-07-26 2012-06-07 Snu R&Db Foundation Real-time monitoring of depletion of high-abundance blood proteins or recovery of low-abundance blood proteins by uv spectrometry
WO2012054333A2 (en) * 2010-10-20 2012-04-26 Merck Sharp & Dohme Corp. Methods for identifying inhibitors of abeta42 oligomers
EP2511296A1 (en) * 2011-04-12 2012-10-17 Araclón Biotech, S. L. Antibody, kit and method for determination of amyloid peptides
CN103827671B (zh) * 2011-05-03 2017-05-03 联邦科学与工业研究组织 用于检测神经疾病的方法
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
JP7434144B2 (ja) * 2018-02-27 2024-02-20 株式会社島津製作所 ＡＰＰ６６９－ｘのＮ末端を特異的に認識する抗体、及び免疫測定法
CN113884683A (zh) * 2020-07-30 2022-01-04 山东京济生物工程有限公司 一种快速检测Aβ42的双抗体夹心ELISA试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811310A (en) * 1986-09-30 1998-09-22 Albert Einstein College Of Medicine Of Yeshiva Univ. The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease
AU7121191A (en) * 1990-02-26 1991-10-10 Albert Einstein College Of Medicine Of Yeshiva University Diagnostic assay for alzheimer's disease
US7427392B1 (en) * 1994-11-14 2008-09-23 Elan Pharmaceuticals, Inc. Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau
US7964192B1 (en) * 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
ES2255280T3 (es) * 1998-07-03 2006-06-16 Innogenetics N.V. Diagnostico diferencial de la neurodegeneracion.
AU2001269127A1 (en) * 2000-07-06 2002-01-14 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw A novel app mutation associated with an unusual alzheimer's disease pathology
EP1371986A1 (en) * 2002-06-06 2003-12-17 ABETA GmbH Diagnosis of Alzheimer's disease based on the hAbeta42:hAbeta40 ratio
TWI374893B (en) * 2003-05-30 2012-10-21 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
KR20080005260A (ko) * 2005-05-05 2008-01-10 머크 앤드 캄파니 인코포레이티드 알츠하이머 질환의 예방 및 치료를 위한 펩티드 접합체조성물 및 방법

Also Published As

Publication number Publication date
IL202598A (en) 2015-10-29
PT2183599E (pt) 2012-02-13
BRPI0721871A2 (pt) 2014-02-18
US20090035790A1 (en) 2009-02-05
ATE533059T1 (de) 2011-11-15
KR20100046168A (ko) 2010-05-06
IL202598A0 (en) 2010-06-30
KR101461538B1 (ko) 2014-11-14
RU2009143671A (ru) 2011-05-27
RS52124B (en) 2012-08-31
US20190178899A1 (en) 2019-06-13
JP2010535328A (ja) 2010-11-18
EP2183599B1 (en) 2011-11-09
JP5657382B2 (ja) 2015-01-21
PL2183599T3 (pl) 2012-04-30
CA2689024A1 (en) 2009-02-05
CY1112553T1 (el) 2016-02-10
CL2007003513A1 (es) 2009-02-06
HRP20120020T1 (hr) 2012-03-31
AR064186A1 (es) 2009-03-18
EP2020602A1 (en) 2009-02-04
MX2009013009A (es) 2010-03-29
SI2183599T1 (sl) 2012-03-30
DK2183599T3 (da) 2012-02-27
ES2377151T3 (es) 2012-03-22
RU2461837C2 (ru) 2012-09-20
AU2007357025B2 (en) 2014-10-23
CN101861521B (zh) 2014-03-12
EP2183599A1 (en) 2010-05-12
WO2009015696A1 (en) 2009-02-05
AU2007357025A1 (en) 2009-02-05
CN101861521A (zh) 2010-10-13

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