CA2681878A1 - Genes codant pour la z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations - Google Patents
Genes codant pour la z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations Download PDFInfo
- Publication number
- CA2681878A1 CA2681878A1 CA002681878A CA2681878A CA2681878A1 CA 2681878 A1 CA2681878 A1 CA 2681878A1 CA 002681878 A CA002681878 A CA 002681878A CA 2681878 A CA2681878 A CA 2681878A CA 2681878 A1 CA2681878 A1 CA 2681878A1
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- Prior art keywords
- synthase
- fpp
- cell
- seq
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
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- Zoology (AREA)
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- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
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- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0754235 | 2007-04-03 | ||
| FR0754235A FR2914652B1 (fr) | 2007-04-03 | 2007-04-03 | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
| PCT/FR2008/050576 WO2008142318A2 (fr) | 2007-04-03 | 2008-04-02 | Genes codant pour la z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
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| CA2681878A1 true CA2681878A1 (fr) | 2008-11-27 |
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| ES (1) | ES2426388T3 (enExample) |
| FR (1) | FR2914652B1 (enExample) |
| WO (1) | WO2008142318A2 (enExample) |
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| FR2914652B1 (fr) * | 2007-04-03 | 2013-01-18 | Librophyt | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
| US9297004B2 (en) | 2008-03-06 | 2016-03-29 | Firmenich Sa | Method for producing α-santalene |
| ES2535722T3 (es) * | 2008-12-05 | 2015-05-14 | Keygene N.V. | Farneseno sintasa |
| WO2010067309A1 (en) * | 2008-12-11 | 2010-06-17 | Firmenich Sa | Method for producing beta-santalene |
| JP5058332B2 (ja) | 2010-07-14 | 2012-10-24 | 住友ゴム工業株式会社 | イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ |
| CA2837664C (en) * | 2011-05-31 | 2022-12-06 | Keygene N.V. | Pest resistant plants with 7-epizingiberene synthase activity and methods of making same |
| US8952221B2 (en) * | 2011-07-06 | 2015-02-10 | Board Of Trustees Of Michigan State University | Enzymes that synthesize zingiberene |
| CN102533600B (zh) * | 2011-12-30 | 2013-02-27 | 中国科学院南海海洋研究所 | 海洋链霉菌、吡喃型倍半萜类化合物及其制备方法和用途 |
| EP2850193A4 (en) | 2012-05-11 | 2016-05-11 | Donald Danforth Plant Sci Ct | PROCESS FOR THE PREPARATION OF TERPENES HAVING HIGH YIELD |
| BR112015004224A2 (pt) * | 2012-09-12 | 2017-08-08 | Sumitomo Rubber Ind | oligômero de isopreno, poli-isopreno, processo para produção de oligômero de isopreno e poli-isopreno, composição de borracha e pneumático |
| EP2925869B1 (en) | 2012-11-30 | 2017-09-20 | Keygene N.V. | Trichome specific promoters |
| CN105555959B (zh) * | 2013-09-19 | 2020-10-27 | 弗门尼舍有限公司 | 用于生产芳香醇的方法 |
| KR101642738B1 (ko) * | 2014-08-08 | 2016-07-26 | 경상대학교산학협력단 | α-산탈렌의 생산 방법 |
| KR101663087B1 (ko) * | 2015-12-30 | 2016-10-06 | 경상대학교산학협력단 | α-산탈렌의 생산 방법 |
| US10499584B2 (en) | 2016-05-27 | 2019-12-10 | New West Genetics | Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles |
| NL2018457B1 (en) | 2017-03-02 | 2018-09-21 | Isobionics B V | Santalene Synthase |
| CN106857415B (zh) * | 2017-03-10 | 2020-03-27 | 中国农业科学院植物保护研究所 | 快速定向获取麦长管蚜低龄有翅若蚜的方法 |
| CN106995848B (zh) * | 2017-04-10 | 2019-11-01 | 中国农业科学院蔬菜花卉研究所 | 番茄腺毛性状的连锁标记及其应用 |
| CN108753744B (zh) * | 2018-06-27 | 2022-03-11 | 中国科学院成都生物研究所 | 倍半萜环化酶及其制备与应用、2Z,4E-α-芷香乙烷合成方法 |
| CN109666668B (zh) * | 2019-01-24 | 2022-04-15 | 天津大学 | 一种小萼苔倍半萜合成酶MTa及其基因序列 |
| CA3145253A1 (en) * | 2019-07-01 | 2021-01-07 | 22Nd Century Limited, Llc | Cannabis terpene synthase promoters for the manipulation of terpene biosynthesis in trichomes |
| CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
| CN112626132B (zh) * | 2020-12-15 | 2022-08-26 | 中国农业科学院烟草研究所 | 西柏烷二萜的微生物生产方法 |
| CN112899208B (zh) * | 2021-02-08 | 2022-10-18 | 江南大学 | 一种提高重组菌西柏三烯一醇产量的方法 |
| CN112980809B (zh) * | 2021-03-17 | 2023-04-11 | 云南中烟工业有限责任公司 | 一种烟草法尼基焦磷酸合酶基因及其应用 |
| CN116790572B (zh) * | 2023-06-09 | 2024-04-09 | 中国中医科学院中药研究所 | SoSTPS5在作为倍半萜合酶中的应用 |
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| IL71691A (en) | 1984-04-27 | 1991-04-15 | Yeda Res & Dev | Production of interferon-ypsilon |
| US5290924A (en) | 1987-02-06 | 1994-03-01 | Last David I | Recombinant promoter for gene expression in monocotyledonous plants |
| US5047335A (en) | 1988-12-21 | 1991-09-10 | The Regents Of The University Of Calif. | Process for controlling intracellular glycosylation of proteins |
| AU2778992A (en) | 1991-10-07 | 1993-05-03 | Idaho Research Foundation Inc., The | Genetic construct for selection of homologous recombinants on a single selective medium |
| FR2706909B1 (enExample) | 1993-06-25 | 1995-09-29 | Rhone Poulenc Agrochimie | |
| US5876964A (en) | 1997-10-16 | 1999-03-02 | Washington State University Research Foundation | Geranyl diphosphate synthase from mint |
| AU2490399A (en) | 1998-02-02 | 1999-08-16 | Regents Of The University Of California, The | Germacrene c synthase gene of (lycopersicon esculentum) |
| AR022383A1 (es) | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
| AU5824400A (en) | 1999-09-16 | 2001-04-17 | HOGE-MEPPELINK, Anneke | Vascular-specific promoters |
| US20040234968A1 (en) | 2000-01-20 | 2004-11-25 | Croteau Rodney B | Plant oil gland nucleic acid molecules and methods of use |
| US6730826B2 (en) | 2000-03-22 | 2004-05-04 | University Of Kentucky Research Foundation | Plant trichome gland specific promoter sequence |
| US20040249219A1 (en) | 2000-07-05 | 2004-12-09 | Saucy Gabriel G. | Method of making teprenone |
| EP1636333A4 (en) * | 2003-06-19 | 2007-10-24 | Evogene Ltd | NUCLEOTIDE SEQUENCES FOR REGULATING GENE EXPRESSION IN VEGETABLE TRICHROMES, AND HYBRID GENES AND METHODS IN WHICH THEY INTERVENE |
| FR2876387B1 (fr) | 2004-10-13 | 2010-09-24 | Librophyt | Promoteurs vegetaux et utilisations |
| FR2881143B1 (fr) | 2005-01-27 | 2010-12-17 | Librophyt | Systeme de production de terpenoides dans les plantes |
| FR2914652B1 (fr) * | 2007-04-03 | 2013-01-18 | Librophyt | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
-
2007
- 2007-04-03 FR FR0754235A patent/FR2914652B1/fr not_active Expired - Fee Related
-
2008
- 2008-04-02 ES ES08788102T patent/ES2426388T3/es active Active
- 2008-04-02 JP JP2010501569A patent/JP5369089B2/ja not_active Expired - Fee Related
- 2008-04-02 EP EP08788102.5A patent/EP2132305B1/fr not_active Not-in-force
- 2008-04-02 CA CA002681878A patent/CA2681878A1/fr not_active Abandoned
- 2008-04-02 US US12/593,688 patent/US8629321B2/en not_active Expired - Fee Related
- 2008-04-02 WO PCT/FR2008/050576 patent/WO2008142318A2/fr not_active Ceased
- 2008-04-02 CN CN2008800113106A patent/CN101688191B/zh not_active Expired - Fee Related
-
2013
- 2013-12-30 US US14/143,539 patent/US20140154768A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100138954A1 (en) | 2010-06-03 |
| JP2010523099A (ja) | 2010-07-15 |
| FR2914652A1 (fr) | 2008-10-10 |
| FR2914652B1 (fr) | 2013-01-18 |
| US20140154768A1 (en) | 2014-06-05 |
| EP2132305B1 (fr) | 2013-05-15 |
| ES2426388T3 (es) | 2013-10-23 |
| WO2008142318A2 (fr) | 2008-11-27 |
| JP5369089B2 (ja) | 2013-12-18 |
| CN101688191B (zh) | 2013-05-01 |
| CN101688191A (zh) | 2010-03-31 |
| US8629321B2 (en) | 2014-01-14 |
| WO2008142318A3 (fr) | 2009-01-15 |
| EP2132305A2 (fr) | 2009-12-16 |
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