CN101688191B - 具有多种产物的z,z-法呢基二磷酸合酶和倍半萜合酶的编码基因及其应用 - Google Patents
具有多种产物的z,z-法呢基二磷酸合酶和倍半萜合酶的编码基因及其应用 Download PDFInfo
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- CN101688191B CN101688191B CN2008800113106A CN200880011310A CN101688191B CN 101688191 B CN101688191 B CN 101688191B CN 2008800113106 A CN2008800113106 A CN 2008800113106A CN 200880011310 A CN200880011310 A CN 200880011310A CN 101688191 B CN101688191 B CN 101688191B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0754235 | 2007-04-03 | ||
| FR0754235A FR2914652B1 (fr) | 2007-04-03 | 2007-04-03 | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
| PCT/FR2008/050576 WO2008142318A2 (fr) | 2007-04-03 | 2008-04-02 | Genes codant pour la z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101688191A CN101688191A (zh) | 2010-03-31 |
| CN101688191B true CN101688191B (zh) | 2013-05-01 |
Family
ID=38670598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008800113106A Expired - Fee Related CN101688191B (zh) | 2007-04-03 | 2008-04-02 | 具有多种产物的z,z-法呢基二磷酸合酶和倍半萜合酶的编码基因及其应用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8629321B2 (enExample) |
| EP (1) | EP2132305B1 (enExample) |
| JP (1) | JP5369089B2 (enExample) |
| CN (1) | CN101688191B (enExample) |
| CA (1) | CA2681878A1 (enExample) |
| ES (1) | ES2426388T3 (enExample) |
| FR (1) | FR2914652B1 (enExample) |
| WO (1) | WO2008142318A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2914652B1 (fr) * | 2007-04-03 | 2013-01-18 | Librophyt | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
| WO2009109597A1 (en) | 2008-03-06 | 2009-09-11 | Firmenich Sa | Method for producing alpha- santalene |
| WO2010064897A1 (en) * | 2008-12-05 | 2010-06-10 | Keygene N.V. | Farmesene synthase |
| ES2626456T3 (es) * | 2008-12-11 | 2017-07-25 | Firmenich Sa | Procedimiento enzimático para producir beta-santaleno y la enzima correspondiente |
| JP5058332B2 (ja) | 2010-07-14 | 2012-10-24 | 住友ゴム工業株式会社 | イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ |
| EP2714901B1 (en) | 2011-05-31 | 2024-09-18 | Keygene N.V. | Pest resistant plants |
| US8952221B2 (en) * | 2011-07-06 | 2015-02-10 | Board Of Trustees Of Michigan State University | Enzymes that synthesize zingiberene |
| CN102533600B (zh) * | 2011-12-30 | 2013-02-27 | 中国科学院南海海洋研究所 | 海洋链霉菌、吡喃型倍半萜类化合物及其制备方法和用途 |
| WO2013170265A1 (en) * | 2012-05-11 | 2013-11-14 | Donald Danforth Plant Science Center | Methods for high yield production of terpenes |
| JP6468512B2 (ja) * | 2012-09-12 | 2019-02-13 | 住友ゴム工業株式会社 | イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ |
| BR112015012270A2 (pt) | 2012-11-30 | 2017-09-26 | Keygene Nv | planta, célula de planta, tecido de planta ou orgão transgênica(o), sequência de ácido nucleico isolada, fragmento, gene quimérico, vetor, célula de planta ou planta transgênica, e, método para produzir uma célula de planta ou planta transgênica |
| US9909145B2 (en) * | 2013-09-19 | 2018-03-06 | Firmenich Sa | Method for producing fragrant alcohols |
| KR101642738B1 (ko) * | 2014-08-08 | 2016-07-26 | 경상대학교산학협력단 | α-산탈렌의 생산 방법 |
| KR101663087B1 (ko) * | 2015-12-30 | 2016-10-06 | 경상대학교산학협력단 | α-산탈렌의 생산 방법 |
| US10499584B2 (en) | 2016-05-27 | 2019-12-10 | New West Genetics | Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles |
| NL2018457B1 (en) | 2017-03-02 | 2018-09-21 | Isobionics B V | Santalene Synthase |
| CN106857415B (zh) * | 2017-03-10 | 2020-03-27 | 中国农业科学院植物保护研究所 | 快速定向获取麦长管蚜低龄有翅若蚜的方法 |
| CN106995848B (zh) * | 2017-04-10 | 2019-11-01 | 中国农业科学院蔬菜花卉研究所 | 番茄腺毛性状的连锁标记及其应用 |
| CN108753744B (zh) * | 2018-06-27 | 2022-03-11 | 中国科学院成都生物研究所 | 倍半萜环化酶及其制备与应用、2Z,4E-α-芷香乙烷合成方法 |
| CN109666668B (zh) * | 2019-01-24 | 2022-04-15 | 天津大学 | 一种小萼苔倍半萜合成酶MTa及其基因序列 |
| CA3145253A1 (en) * | 2019-07-01 | 2021-01-07 | 22Nd Century Limited, Llc | Cannabis terpene synthase promoters for the manipulation of terpene biosynthesis in trichomes |
| CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
| CN112626132B (zh) * | 2020-12-15 | 2022-08-26 | 中国农业科学院烟草研究所 | 西柏烷二萜的微生物生产方法 |
| CN112899208B (zh) * | 2021-02-08 | 2022-10-18 | 江南大学 | 一种提高重组菌西柏三烯一醇产量的方法 |
| CN112980809B (zh) * | 2021-03-17 | 2023-04-11 | 云南中烟工业有限责任公司 | 一种烟草法尼基焦磷酸合酶基因及其应用 |
| CN116790572B (zh) * | 2023-06-09 | 2024-04-09 | 中国中医科学院中药研究所 | SoSTPS5在作为倍半萜合酶中的应用 |
| CN119039411B (zh) * | 2024-09-12 | 2025-12-12 | 广西壮族自治区农业科学院 | 檀香SaERF89基因及其在生物合成(Z)-α-反式-香柠檬醇中的应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040249219A1 (en) * | 2000-07-05 | 2004-12-09 | Saucy Gabriel G. | Method of making teprenone |
| WO2004111183A2 (en) * | 2003-06-19 | 2004-12-23 | Evogene Ltd. | Plant trichome-specific promoter and leucoplast signal sequence |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL71691A (en) | 1984-04-27 | 1991-04-15 | Yeda Res & Dev | Production of interferon-ypsilon |
| US5290924A (en) | 1987-02-06 | 1994-03-01 | Last David I | Recombinant promoter for gene expression in monocotyledonous plants |
| US5047335A (en) | 1988-12-21 | 1991-09-10 | The Regents Of The University Of Calif. | Process for controlling intracellular glycosylation of proteins |
| AU2778992A (en) | 1991-10-07 | 1993-05-03 | Idaho Research Foundation Inc., The | Genetic construct for selection of homologous recombinants on a single selective medium |
| FR2706909B1 (enExample) | 1993-06-25 | 1995-09-29 | Rhone Poulenc Agrochimie | |
| US5876964A (en) | 1997-10-16 | 1999-03-02 | Washington State University Research Foundation | Geranyl diphosphate synthase from mint |
| US6342380B1 (en) | 1998-02-02 | 2002-01-29 | The Regents Of The University Of California | Germacrene C synthase gene of Lycopersicon esculentum |
| AR022383A1 (es) | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
| WO2001020008A2 (en) | 1999-09-16 | 2001-03-22 | Universiteit Leiden | Vascular-specific promoters |
| US20040234968A1 (en) | 2000-01-20 | 2004-11-25 | Croteau Rodney B | Plant oil gland nucleic acid molecules and methods of use |
| US6730826B2 (en) | 2000-03-22 | 2004-05-04 | University Of Kentucky Research Foundation | Plant trichome gland specific promoter sequence |
| FR2876387B1 (fr) | 2004-10-13 | 2010-09-24 | Librophyt | Promoteurs vegetaux et utilisations |
| FR2881143B1 (fr) | 2005-01-27 | 2010-12-17 | Librophyt | Systeme de production de terpenoides dans les plantes |
| FR2914652B1 (fr) * | 2007-04-03 | 2013-01-18 | Librophyt | Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations |
-
2007
- 2007-04-03 FR FR0754235A patent/FR2914652B1/fr not_active Expired - Fee Related
-
2008
- 2008-04-02 US US12/593,688 patent/US8629321B2/en not_active Expired - Fee Related
- 2008-04-02 CA CA002681878A patent/CA2681878A1/fr not_active Abandoned
- 2008-04-02 JP JP2010501569A patent/JP5369089B2/ja not_active Expired - Fee Related
- 2008-04-02 WO PCT/FR2008/050576 patent/WO2008142318A2/fr not_active Ceased
- 2008-04-02 ES ES08788102T patent/ES2426388T3/es active Active
- 2008-04-02 CN CN2008800113106A patent/CN101688191B/zh not_active Expired - Fee Related
- 2008-04-02 EP EP08788102.5A patent/EP2132305B1/fr not_active Not-in-force
-
2013
- 2013-12-30 US US14/143,539 patent/US20140154768A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040249219A1 (en) * | 2000-07-05 | 2004-12-09 | Saucy Gabriel G. | Method of making teprenone |
| WO2004111183A2 (en) * | 2003-06-19 | 2004-12-23 | Evogene Ltd. | Plant trichome-specific promoter and leucoplast signal sequence |
Non-Patent Citations (2)
| Title |
|---|
| P. F. HEINSTEIN等.Biosynthesis of Gossypol INCORPORATION OF MEVALONATE-2-14C AND ISOPRENYL PYROPHOSPHATES.《THE JOURNAL OF BIOLOGICAL CHEMISTRY》.1970,第245卷(第18期),4658-4665. * |
| STEVE R. ADAMS等.EVIDENCE FOR TRANS-TRANS AND CIS-CIS FARNESYL PYROPHOSPHATE SYNTHESIS IN GOSSIPIUM HIRSUTUM.《Phytochemist》.1973,第12卷2167-2172. * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5369089B2 (ja) | 2013-12-18 |
| FR2914652B1 (fr) | 2013-01-18 |
| FR2914652A1 (fr) | 2008-10-10 |
| JP2010523099A (ja) | 2010-07-15 |
| US20140154768A1 (en) | 2014-06-05 |
| US8629321B2 (en) | 2014-01-14 |
| US20100138954A1 (en) | 2010-06-03 |
| WO2008142318A3 (fr) | 2009-01-15 |
| EP2132305B1 (fr) | 2013-05-15 |
| WO2008142318A2 (fr) | 2008-11-27 |
| CA2681878A1 (fr) | 2008-11-27 |
| EP2132305A2 (fr) | 2009-12-16 |
| ES2426388T3 (es) | 2013-10-23 |
| CN101688191A (zh) | 2010-03-31 |
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Granted publication date: 20130501 Termination date: 20170402 |