CA2672727A1 - Composes d'agonistes et d'antagonistes des recepteurs de sphingosine-1-phosphate - Google Patents

Composes d'agonistes et d'antagonistes des recepteurs de sphingosine-1-phosphate Download PDF

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Publication number
CA2672727A1
CA2672727A1 CA002672727A CA2672727A CA2672727A1 CA 2672727 A1 CA2672727 A1 CA 2672727A1 CA 002672727 A CA002672727 A CA 002672727A CA 2672727 A CA2672727 A CA 2672727A CA 2672727 A1 CA2672727 A1 CA 2672727A1
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Canada
Prior art keywords
alkyl
substituted
optionally substituted
phenyl
aryl
Prior art date
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Abandoned
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CA002672727A
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English (en)
Inventor
Grier A. Wallace
Eric C. Breinlinger
Kevin P. Cusack
Shannon R. Fix-Stenzel
Thomas D. Gordon
Adrian D. Hobson
Martin E. Hayes
Graham K. Ansell
Pintipa Grongsaard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Grier A. Wallace
Eric C. Breinlinger
Kevin P. Cusack
Shannon R. Fix-Stenzel
Thomas D. Gordon
Adrian D. Hobson
Martin E. Hayes
Graham K. Ansell
Pintipa Grongsaard
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39562856&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2672727(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories, Grier A. Wallace, Eric C. Breinlinger, Kevin P. Cusack, Shannon R. Fix-Stenzel, Thomas D. Gordon, Adrian D. Hobson, Martin E. Hayes, Graham K. Ansell, Pintipa Grongsaard filed Critical Abbott Laboratories
Publication of CA2672727A1 publication Critical patent/CA2672727A1/fr
Abandoned legal-status Critical Current

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    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
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    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/14—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
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    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826—Acyclic unsaturated acids
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    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
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CA002672727A 2006-12-21 2007-12-21 Composes d'agonistes et d'antagonistes des recepteurs de sphingosine-1-phosphate Abandoned CA2672727A1 (fr)

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RU2009128062A (ru) 2011-01-27
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AR064650A1 (es) 2009-04-15
EP2120575A1 (fr) 2009-11-25
NO20092376L (no) 2009-06-22
MX2009006751A (es) 2009-06-30
DOP2009000149A (es) 2010-05-15
EP2120575A4 (fr) 2011-04-27
PE20081561A1 (es) 2008-10-30
CO6180436A2 (es) 2010-07-19
AU2007338700A1 (en) 2008-07-03
ECSP099435A (es) 2009-07-31
JP2010513532A (ja) 2010-04-30
BRPI0720478A2 (pt) 2014-01-14
WO2008079382A1 (fr) 2008-07-03
CL2007003784A1 (es) 2008-06-27
TW200838497A (en) 2008-10-01
CR10872A (es) 2009-07-23

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