CA2671939C - Biomarker for detecting prostate cancer - Google Patents

Biomarker for detecting prostate cancer Download PDF

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Publication number
CA2671939C
CA2671939C CA2671939A CA2671939A CA2671939C CA 2671939 C CA2671939 C CA 2671939C CA 2671939 A CA2671939 A CA 2671939A CA 2671939 A CA2671939 A CA 2671939A CA 2671939 C CA2671939 C CA 2671939C
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CA
Canada
Prior art keywords
fragment
seq
sequence homology
prostate cancer
transcription factor
Prior art date
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CA2671939A
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English (en)
French (fr)
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CA2671939A1 (en
Inventor
Hardev Pandha
Richard George Leonard Morgan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Surrey
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University of Surrey
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Publication date
Application filed by University of Surrey filed Critical University of Surrey
Publication of CA2671939A1 publication Critical patent/CA2671939A1/en
Application granted granted Critical
Publication of CA2671939C publication Critical patent/CA2671939C/en
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Classifications

    • G01N33/57555—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CA2671939A 2006-12-19 2007-12-19 Biomarker for detecting prostate cancer Active CA2671939C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0625321.5A GB0625321D0 (en) 2006-12-19 2006-12-19 Cancer biomarker
GB0625321.5 2006-12-19
GBGB0719792.4A GB0719792D0 (en) 2006-12-19 2007-10-10 Cancer biomarkers
GB0719792.4 2007-10-10
PCT/GB2007/004902 WO2008075056A1 (en) 2006-12-19 2007-12-19 Cancer biomarkers

Publications (2)

Publication Number Publication Date
CA2671939A1 CA2671939A1 (en) 2008-06-26
CA2671939C true CA2671939C (en) 2017-10-03

Family

ID=39265269

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2671939A Active CA2671939C (en) 2006-12-19 2007-12-19 Biomarker for detecting prostate cancer

Country Status (19)

Country Link
US (1) US8460882B2 (enExample)
EP (1) EP2115472B1 (enExample)
JP (1) JP5683108B2 (enExample)
CN (1) CN101675341B (enExample)
AU (1) AU2007335999B2 (enExample)
BR (1) BRPI0720371B8 (enExample)
CA (1) CA2671939C (enExample)
CY (1) CY1115178T1 (enExample)
DK (1) DK2115472T3 (enExample)
ES (1) ES2445185T3 (enExample)
GB (2) GB0625321D0 (enExample)
IL (1) IL199241A (enExample)
MX (1) MX2009006378A (enExample)
NZ (1) NZ577548A (enExample)
PL (1) PL2115472T3 (enExample)
PT (1) PT2115472E (enExample)
RU (1) RU2460075C2 (enExample)
SI (1) SI2115472T1 (enExample)
WO (1) WO2008075056A1 (enExample)

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US8461126B2 (en) 2005-10-14 2013-06-11 Phigenix, Inc. Targeting EN2, PAX2, and/or DEFB1 for treatment of prostate conditions
DE102006047617B4 (de) 2006-10-09 2008-11-27 Clariant International Limited Verfahren zur Herstellung basischer (Meth)acrylamide
DE102008017216B4 (de) 2008-04-04 2013-08-14 Clariant International Ltd. Kontinuierliches Verfahren zur Herstellung von Fettsäureamiden
GB0823445D0 (en) * 2008-12-23 2009-01-28 Univ Surrey Biomarker
DE102009031059A1 (de) 2009-06-30 2011-01-05 Clariant International Ltd. Vorrichtung zur kontinuierlichen Durchführung chemischer Reaktionen bei hohen Temperaturen
GB0912175D0 (en) * 2009-07-13 2009-08-26 Univ Surrey Biomarker
GB0912190D0 (en) * 2009-07-13 2009-08-26 Univ Surrey Biomarker
AU2010272371A1 (en) * 2009-07-13 2012-02-02 The University Of Surrey Therapeutic peptides, polypeptides ans nucleic acid sequences
DE102009042523B4 (de) 2009-09-22 2012-02-16 Clariant International Ltd. Vorrichtung und Verfahren zur kontinuierlichen Durchführung heterogen katalysierter chemischer Reaktionen bei hohen Temperaturen
DE102009042522A1 (de) 2009-09-22 2011-04-07 Clariant International Ltd. Kontinuierliches Umesterungsverfahren
GB0921329D0 (en) * 2009-12-04 2010-01-20 Univ Surrey Biomarker
DE102010056565A1 (de) 2010-12-30 2012-07-05 Clariant International Ltd. Verfahren zur Modifizierung Hydroxylgruppen tragender Polymere
US20140106363A1 (en) * 2011-05-12 2014-04-17 Noviogendix Research B.V. Molecular markers in prostate cancer
AU2012252426A1 (en) * 2011-05-12 2013-11-28 Noviogendix Research B.V. Molecular markers in prostate cancer
WO2013037118A1 (zh) * 2011-09-16 2013-03-21 上海长海医院 前列腺癌的生物学标志物、治疗靶点及其用途
MX2014006662A (es) * 2011-12-05 2015-04-16 Phigenix Inc Direccionamiento de en2, pax2, y/o defb1 para tratamiento de afecciones de la próstata.
WO2014005138A1 (en) * 2012-06-29 2014-01-03 Kerschensteiner Daniel A Colorimetric gelatinase assay
US10613087B2 (en) * 2012-08-10 2020-04-07 Analiza, Inc. Methods and devices for analyzing species to determine diseases
EP2994753B1 (en) * 2013-05-09 2018-03-07 The Procter and Gamble Company Method and system for assessing health condition
WO2016102560A1 (en) * 2014-12-23 2016-06-30 The University Of Surrey Glycosylated biomarker
KR101698654B1 (ko) * 2014-12-24 2017-01-20 포항공과대학교 산학협력단 En2에 특이적으로 결합하는 dna 압타머 및 이의 용도
JP6745820B2 (ja) * 2015-05-29 2020-08-26 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 前立腺がん予後判定の方法
CN108289929A (zh) * 2015-09-23 2018-07-17 国家科学研究中心 用于治疗神经退行性障碍的同源异型蛋白
CN106282347A (zh) * 2016-08-17 2017-01-04 中南大学 HoxC11作为生物标志物在制备肺腺癌的预诊断试剂中的应用
EP3564365B1 (en) * 2016-12-28 2023-01-25 Guangzhou Institutes Of Biomedicine And Health Chinese Academy Of Sciences Transdifferentation of b lymphoid cells into t cells
KR101777085B1 (ko) 2017-02-23 2017-09-11 주식회사 성균바이오텍 En2 단백질의 면역원성 단편 펩타이드 또는 이를 특이적으로 인식하는 항체 조성물
KR101777259B1 (ko) * 2017-07-14 2017-09-13 주식회사 무진메디 En2 단백질을 특이적으로 인식하는 단클론 항체 또는 이를 함유하는 전립선암 진단용 조성물
KR101777254B1 (ko) 2017-07-14 2017-09-13 주식회사 무진메디 En2 단백질을 특이적으로 인식하는 특정 항원으로부터 얻어진 단클론 항체 또는 이를 함유하는 전립선암 진단용 조성물
CN107727729A (zh) * 2017-11-22 2018-02-23 南宁科城汇信息科技有限公司 一种oa候选标志物诊断模型的建立方法
CN107894507A (zh) * 2017-11-22 2018-04-10 南宁科城汇信息科技有限公司 一种发现和鉴定肝癌血清差异表达蛋白和验证标志物蛋白方法
KR101923199B1 (ko) 2018-04-25 2018-11-28 주식회사 무진메디 펩스타틴 a를 함유하는 소변 내 en2 진단용 조성물
CN111363817B (zh) * 2018-12-26 2024-02-02 广州康立明生物科技股份有限公司 基于hoxd12基因的肺癌诊断剂及试剂盒

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WO1999000498A1 (en) * 1997-06-27 1999-01-07 Human Genome Sciences, Inc. Human nk-3 related prostate specific gene-1
RU2234942C2 (ru) * 1998-07-14 2004-08-27 Корикса Корпорейшн Выделенный опухолевый полипептид предстательной железы и кодирующий его полинуклеотид
CA2347081A1 (en) * 1998-10-19 2000-04-27 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
EP1290442B1 (en) 2000-05-30 2013-11-13 Aarhus Universitet An assay method for testing plant material for exposure to herbicides using biomarkers
EP1297182A2 (en) * 2000-06-30 2003-04-02 Epigenomics AG Diagnosis of diseases associated with cell signalling
US20050079492A1 (en) * 2000-09-12 2005-04-14 Burgess Jr. Robert M. Micro-arrayed organization of transcription factor target genes
US20040063216A1 (en) 2000-12-24 2004-04-01 Iser Lubocki Method for detecting biomarkers
NZ527180A (en) 2000-12-24 2007-02-23 Iser Lubocki A method for detecting biomarkers
CA2439854A1 (en) * 2001-03-01 2002-09-12 Epigenomics Ag Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylatoin status of the genes
US6949342B2 (en) * 2001-12-21 2005-09-27 Whitehead Institute For Biomedical Research Prostate cancer diagnosis and outcome prediction by expression analysis
CA2469089A1 (en) * 2003-07-08 2005-01-08 Institut De Recherches Cliniques De Montreal En-2 gene, disgnostic and therapeutic uses thereof
US20060014301A1 (en) 2004-07-13 2006-01-19 Power3 Medical Products, Inc. Antibody-based system for detection of differential protein expression patterns
EP1831399B1 (en) * 2004-12-02 2009-08-05 Epigenomics AG Methods and nucleic acids for the analysis of gene expression associated with the prognosis of prostate cell proliferative disorders
WO2006089091A2 (en) 2005-02-18 2006-08-24 Memorial Sloan-Kettering Cancer Center Methods for detecting minimum residual disease

Also Published As

Publication number Publication date
JP2010513901A (ja) 2010-04-30
EP2115472A1 (en) 2009-11-11
BRPI0720371B8 (pt) 2021-07-27
MX2009006378A (es) 2009-08-24
BRPI0720371A2 (pt) 2013-12-31
JP5683108B2 (ja) 2015-03-11
RU2460075C2 (ru) 2012-08-27
ES2445185T3 (es) 2014-02-28
CN101675341B (zh) 2017-08-08
US20100093558A1 (en) 2010-04-15
US8460882B2 (en) 2013-06-11
NZ577548A (en) 2012-03-30
AU2007335999B2 (en) 2013-09-05
AU2007335999A1 (en) 2008-06-26
GB0625321D0 (en) 2007-01-24
CN101675341A (zh) 2010-03-17
GB0719792D0 (en) 2007-11-21
RU2009127774A (ru) 2011-01-27
BRPI0720371B1 (pt) 2019-05-28
IL199241A (en) 2014-03-31
CA2671939A1 (en) 2008-06-26
SI2115472T1 (sl) 2014-05-30
PT2115472E (pt) 2014-02-14
PL2115472T3 (pl) 2014-05-30
WO2008075056A1 (en) 2008-06-26
DK2115472T3 (da) 2014-02-10
EP2115472B1 (en) 2013-11-06
CY1115178T1 (el) 2016-12-14

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