CA2662350A1 - Antibodies to bone morphogenic proteins and receptors therefor and methods for their use - Google Patents
Antibodies to bone morphogenic proteins and receptors therefor and methods for their use Download PDFInfo
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- CA2662350A1 CA2662350A1 CA002662350A CA2662350A CA2662350A1 CA 2662350 A1 CA2662350 A1 CA 2662350A1 CA 002662350 A CA002662350 A CA 002662350A CA 2662350 A CA2662350 A CA 2662350A CA 2662350 A1 CA2662350 A1 CA 2662350A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82459606P | 2006-09-05 | 2006-09-05 | |
| US60/824,596 | 2006-09-05 | ||
| PCT/US2007/019652 WO2008030611A2 (en) | 2006-09-05 | 2007-09-05 | Antibodies to bone morphogenic proteins and receptors therefor and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2662350A1 true CA2662350A1 (en) | 2008-03-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002662350A Abandoned CA2662350A1 (en) | 2006-09-05 | 2007-09-05 | Antibodies to bone morphogenic proteins and receptors therefor and methods for their use |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110182904A1 (enExample) |
| EP (1) | EP2074144A4 (enExample) |
| JP (1) | JP2010502220A (enExample) |
| KR (1) | KR20090088852A (enExample) |
| CN (1) | CN101627055A (enExample) |
| AU (1) | AU2007292890A1 (enExample) |
| BR (1) | BRPI0714893A2 (enExample) |
| CA (1) | CA2662350A1 (enExample) |
| EA (1) | EA200970250A1 (enExample) |
| IL (1) | IL197199A0 (enExample) |
| MX (1) | MX2009002418A (enExample) |
| NO (1) | NO20091387L (enExample) |
| WO (1) | WO2008030611A2 (enExample) |
| ZA (1) | ZA200901561B (enExample) |
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| WO2010014784A2 (en) | 2008-08-01 | 2010-02-04 | Bristol-Myers Squibb Company | Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases |
| EP2182754B1 (en) * | 2008-10-30 | 2014-01-15 | Telefonaktiebolaget LM Ericsson (publ) | Method and receiver for estimating and reporting a channel quality measure |
| KR101245929B1 (ko) * | 2009-01-20 | 2013-03-22 | 호메이욘 에이치. 자데흐 | 항체 매개된 골질 재생 |
| WO2011056502A1 (en) * | 2009-10-26 | 2011-05-12 | Genentech, Inc. | Bone morphogenetic protein receptor type ii compositions and methods of use |
| EP4190149A1 (en) | 2009-12-25 | 2023-06-07 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having nog established cancer cell line transplanted therein |
| US20130089560A1 (en) * | 2010-03-17 | 2013-04-11 | Oncomed Pharmaceuticals Inc | Bone morphogenetic protein receptor binding agents and methods of their use |
| US11124773B2 (en) | 2010-10-06 | 2021-09-21 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
| HRP20251174T1 (hr) | 2010-11-05 | 2025-11-21 | Novartis Ag | Postupci za liječenje psorijatičnog artritisa uporabom il-17 antagonista |
| AU2014259526B2 (en) * | 2010-11-05 | 2016-02-04 | Novartis Ag | Methods of treating ankylosing spondylitis using IL-17 antagonists |
| EP2749641B1 (en) | 2011-09-07 | 2021-06-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
| EP2772268B8 (en) | 2011-10-28 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
| EP3521310A1 (en) * | 2012-06-14 | 2019-08-07 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | Use of blocking agents of bone morphogenic protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases |
| US20150367034A1 (en) * | 2013-01-25 | 2015-12-24 | Osaka University | Creation of three-dimensional synthetic tissue from pluripotent stem cell-derived cells, and osteochondral regeneration treatment using said synthetic tissue |
| CN104800847A (zh) * | 2014-01-29 | 2015-07-29 | 中国科学院上海巴斯德研究所 | Bmp通路抑制剂在制备卡波氏肉瘤病毒感染疾病治疗药物中的用途 |
| US20160075772A1 (en) * | 2014-09-12 | 2016-03-17 | Regeneron Pharmaceuticals, Inc. | Treatment of Fibrodysplasia Ossificans Progressiva |
| WO2016043577A1 (en) | 2014-09-16 | 2016-03-24 | Academisch Medisch Centrum | Ig-like molecules binding to bmp4 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| KR20170105558A (ko) | 2015-01-30 | 2017-09-19 | 각코우호우징 사이타마이카다이가쿠 | 항 alk2 항체 |
| JP2019522960A (ja) * | 2016-04-21 | 2019-08-22 | アッヴィ・ステムセントルクス・エル・エル・シー | 新規の抗ｂｍｐｒ１ｂ抗体及び使用方法 |
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| CN102397542B (zh) * | 2004-11-18 | 2014-05-07 | 英克隆有限责任公司 | 抗血管内皮生长因子受体-1的抗体 |
| CA2595682A1 (en) | 2005-01-31 | 2006-08-03 | Ablynx N.V. | Method for generating variable domain sequences of heavy chain antibodies |
| US7714016B2 (en) | 2005-04-08 | 2010-05-11 | Medarex, Inc. | Cytotoxic compounds and conjugates with cleavable substrates |
| US20070212703A1 (en) | 2005-09-27 | 2007-09-13 | Stemmer Willem P | Proteinaceous pharmaceuticals and uses thereof |
| US10155816B2 (en) | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
-
2007
- 2007-09-05 WO PCT/US2007/019652 patent/WO2008030611A2/en not_active Ceased
- 2007-09-05 CA CA002662350A patent/CA2662350A1/en not_active Abandoned
- 2007-09-05 JP JP2009527447A patent/JP2010502220A/ja not_active Withdrawn
- 2007-09-05 EP EP07811727A patent/EP2074144A4/en not_active Withdrawn
- 2007-09-05 KR KR1020097006592A patent/KR20090088852A/ko not_active Withdrawn
- 2007-09-05 CN CN200780040982A patent/CN101627055A/zh active Pending
- 2007-09-05 BR BRPI0714893-3A patent/BRPI0714893A2/pt not_active IP Right Cessation
- 2007-09-05 AU AU2007292890A patent/AU2007292890A1/en not_active Abandoned
- 2007-09-05 US US12/440,000 patent/US20110182904A1/en not_active Abandoned
- 2007-09-05 MX MX2009002418A patent/MX2009002418A/es not_active Application Discontinuation
- 2007-09-05 EA EA200970250A patent/EA200970250A1/ru unknown
-
2009
- 2009-02-23 IL IL197199A patent/IL197199A0/en unknown
- 2009-03-04 ZA ZA200901561A patent/ZA200901561B/xx unknown
- 2009-04-03 NO NO20091387A patent/NO20091387L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2074144A4 (en) | 2011-03-16 |
| BRPI0714893A2 (pt) | 2013-05-28 |
| WO2008030611A3 (en) | 2008-12-24 |
| US20110182904A1 (en) | 2011-07-28 |
| ZA200901561B (en) | 2010-03-31 |
| NO20091387L (no) | 2009-06-05 |
| AU2007292890A1 (en) | 2008-03-13 |
| EA200970250A1 (ru) | 2010-02-26 |
| MX2009002418A (es) | 2009-04-23 |
| CN101627055A (zh) | 2010-01-13 |
| EP2074144A2 (en) | 2009-07-01 |
| KR20090088852A (ko) | 2009-08-20 |
| JP2010502220A (ja) | 2010-01-28 |
| WO2008030611A2 (en) | 2008-03-13 |
| IL197199A0 (en) | 2011-08-01 |
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| FZDE | Discontinued |