CA2657947C - Fkbp-l and uses thereof - Google Patents
Fkbp-l and uses thereof Download PDFInfo
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- CA2657947C CA2657947C CA2657947A CA2657947A CA2657947C CA 2657947 C CA2657947 C CA 2657947C CA 2657947 A CA2657947 A CA 2657947A CA 2657947 A CA2657947 A CA 2657947A CA 2657947 C CA2657947 C CA 2657947C
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- fkbp
- seq
- polypeptide
- amino acid
- acid sequence
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C12Y502/01—Cis-trans-Isomerases (5.2.1)
- C12Y502/01008—Peptidylprolyl isomerase (5.2.1.8), i.e. cyclophilin
Landscapes
- Health & Medical Sciences (AREA)
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| GBGB0611405.2A GB0611405D0 (en) | 2006-06-09 | 2006-06-09 | FKBP-L: A novel inhibitor of angiogenesis |
| PCT/GB2007/002107 WO2007141533A2 (en) | 2006-06-09 | 2007-06-08 | Fkbp-l and uses thereof |
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| WO2005044839A2 (en) | 2003-11-05 | 2005-05-19 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| CA2677045C (en) | 2007-01-31 | 2016-10-18 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
| CA2682174C (en) | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| GB0724393D0 (en) * | 2007-12-14 | 2008-01-23 | Univ Ulster | Use of FKBPL gene to identify a cause of infertility |
| US20110144306A1 (en) | 2008-07-23 | 2011-06-16 | President And Fellows Of Harvard College | Ligation of stapled polypeptides |
| WO2010034032A2 (en) | 2008-09-22 | 2010-03-25 | Aileron Therapeutic, Inc. | Methods for preparing purified polypeptide compositions |
| US9175047B2 (en) | 2009-01-14 | 2015-11-03 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| GB0908589D0 (en) * | 2009-05-19 | 2009-06-24 | Univ Belfast | Assay method |
| CA2768299C (en) * | 2009-07-13 | 2018-03-20 | President And Fellows Of Harvard College | Bifunctional stapled polypeptides and uses thereof |
| AU2010298338A1 (en) | 2009-09-22 | 2012-04-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2012021875A1 (en) | 2010-08-13 | 2012-02-16 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles with triazole linkers |
| WO2012040459A2 (en) | 2010-09-22 | 2012-03-29 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
| US9487562B2 (en) | 2011-06-17 | 2016-11-08 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of RAB GTPase function |
| WO2013052803A2 (en) | 2011-10-07 | 2013-04-11 | Radiorx, Inc. | Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products |
| CN108929375A (zh) | 2011-10-18 | 2018-12-04 | 爱勒让治疗公司 | 拟肽大环化合物 |
| CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| CN112500466B (zh) | 2012-02-15 | 2022-05-03 | 艾瑞朗医疗公司 | 拟肽大环化合物 |
| SMT202100337T1 (it) | 2012-09-26 | 2021-07-12 | Harvard College | Peptidi graffati bloccati con prolina e loro usi |
| CN104812384B (zh) | 2012-11-01 | 2020-09-18 | 爱勒让治疗公司 | 二取代的氨基酸及其制备和使用方法 |
| JP6568515B2 (ja) | 2013-03-13 | 2019-08-28 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ステープルドおよびステッチドポリペプチドならびにその使用 |
| CN105492460A (zh) | 2013-06-14 | 2016-04-13 | 哈佛大学的校长及成员们 | 稳定化多肽胰岛素受体调控剂 |
| EP3145523A4 (en) | 2014-05-21 | 2018-02-21 | President and Fellows of Harvard College | Ras inhibitory peptides and uses thereof |
| US10905739B2 (en) | 2014-09-24 | 2021-02-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| EP3197478A4 (en) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| SG11201707750YA (en) | 2015-03-20 | 2017-10-30 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| WO2017004548A1 (en) | 2015-07-01 | 2017-01-05 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| CN108368161A (zh) | 2015-09-10 | 2018-08-03 | 艾瑞朗医疗公司 | 作为mcl-1调节剂的拟肽大环化合物 |
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| US11376308B2 (en) | 2016-10-19 | 2022-07-05 | Royal College Of Surgeons In Ireland | Use of FKBP-L polypeptides and nucleic acids for the treatment of obesity |
| CN108362870A (zh) * | 2017-01-27 | 2018-08-03 | 武汉三鹰生物技术有限公司 | 一种用于人fkbpl蛋白的酶联免疫检测及制备方法 |
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| CN111603567B (zh) | 2019-02-22 | 2024-12-27 | 赣江新区博瑞创新医药有限公司 | Cd44靶向多臂偶联物 |
| CN113702632A (zh) * | 2021-09-02 | 2021-11-26 | 深圳市光与生物科技有限公司 | 一种快速检测子痫前期的免疫层析检测卡及其制备方法与应用 |
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-
2006
- 2006-06-09 GB GBGB0611405.2A patent/GB0611405D0/en not_active Ceased
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2007
- 2007-06-08 SI SI200731701T patent/SI2040728T1/sl unknown
- 2007-06-08 EP EP07733118.9A patent/EP2040728B1/en not_active Not-in-force
- 2007-06-08 WO PCT/GB2007/002107 patent/WO2007141533A2/en not_active Ceased
- 2007-06-08 CA CA2657947A patent/CA2657947C/en not_active Expired - Fee Related
- 2007-06-08 NZ NZ600690A patent/NZ600690A/en not_active IP Right Cessation
- 2007-06-08 PT PT77331189T patent/PT2040728E/pt unknown
- 2007-06-08 ES ES07733118.9T patent/ES2548332T3/es active Active
- 2007-06-08 NZ NZ573425A patent/NZ573425A/en not_active IP Right Cessation
- 2007-06-08 AU AU2007255196A patent/AU2007255196B2/en not_active Ceased
- 2007-06-08 HU HUE07733118A patent/HUE028099T2/en unknown
- 2007-06-08 CN CN2007800276683A patent/CN101489575B/zh not_active Expired - Fee Related
- 2007-06-08 JP JP2009513764A patent/JP5474535B2/ja not_active Expired - Fee Related
- 2007-06-08 PL PL07733118T patent/PL2040728T3/pl unknown
- 2007-06-08 US US12/303,343 patent/US9381228B2/en not_active Expired - Fee Related
- 2007-06-08 DK DK07733118.9T patent/DK2040728T3/en active
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2008
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- 2008-12-04 ZA ZA2008/10323A patent/ZA200810323B/en unknown
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2015
- 2015-11-26 CY CY20151101070T patent/CY1116970T1/el unknown
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2016
- 2016-05-31 US US15/169,460 patent/US10577406B2/en not_active Expired - Fee Related
- 2016-05-31 US US15/169,452 patent/US20160340401A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2040728B1 (en) | 2015-09-02 |
| PT2040728E (pt) | 2015-10-29 |
| IL195580A0 (en) | 2011-08-01 |
| WO2007141533A2 (en) | 2007-12-13 |
| ES2548332T3 (es) | 2015-10-15 |
| US20160340401A1 (en) | 2016-11-24 |
| ZA200810323B (en) | 2013-05-29 |
| NZ600690A (en) | 2014-03-28 |
| SI2040728T1 (sl) | 2015-12-31 |
| JP5474535B2 (ja) | 2014-04-16 |
| DK2040728T3 (en) | 2015-10-26 |
| WO2007141533A3 (en) | 2008-07-31 |
| US10577406B2 (en) | 2020-03-03 |
| CN101489575A (zh) | 2009-07-22 |
| EP2040728A2 (en) | 2009-04-01 |
| CY1116970T1 (el) | 2017-04-05 |
| GB0611405D0 (en) | 2006-07-19 |
| AU2007255196B2 (en) | 2013-10-03 |
| JP2009539367A (ja) | 2009-11-19 |
| IL195580A (en) | 2013-07-31 |
| US9381228B2 (en) | 2016-07-05 |
| US20090192085A1 (en) | 2009-07-30 |
| PL2040728T3 (pl) | 2016-02-29 |
| CA2657947A1 (en) | 2007-12-13 |
| CN101489575B (zh) | 2013-08-28 |
| AU2007255196A1 (en) | 2007-12-13 |
| NZ573425A (en) | 2012-07-27 |
| US20160340402A1 (en) | 2016-11-24 |
| HUE028099T2 (en) | 2016-11-28 |
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