AU2007255196B2 - FKBP-L and uses thereof - Google Patents
FKBP-L and uses thereof Download PDFInfo
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- AU2007255196B2 AU2007255196B2 AU2007255196A AU2007255196A AU2007255196B2 AU 2007255196 B2 AU2007255196 B2 AU 2007255196B2 AU 2007255196 A AU2007255196 A AU 2007255196A AU 2007255196 A AU2007255196 A AU 2007255196A AU 2007255196 B2 AU2007255196 B2 AU 2007255196B2
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- fkbp
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y502/00—Cis-trans-isomerases (5.2)
- C12Y502/01—Cis-trans-Isomerases (5.2.1)
- C12Y502/01008—Peptidylprolyl isomerase (5.2.1.8), i.e. cyclophilin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Epidemiology (AREA)
- Zoology (AREA)
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- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
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- Microbiology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Marine Sciences & Fisheries (AREA)
- Mycology (AREA)
- Dispersion Chemistry (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (3)
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| GB0611405.2 | 2006-06-09 | ||
| GBGB0611405.2A GB0611405D0 (en) | 2006-06-09 | 2006-06-09 | FKBP-L: A novel inhibitor of angiogenesis |
| PCT/GB2007/002107 WO2007141533A2 (en) | 2006-06-09 | 2007-06-08 | Fkbp-l and uses thereof |
Publications (2)
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| AU2007255196A1 AU2007255196A1 (en) | 2007-12-13 |
| AU2007255196B2 true AU2007255196B2 (en) | 2013-10-03 |
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| AU2007255196A Ceased AU2007255196B2 (en) | 2006-06-09 | 2007-06-08 | FKBP-L and uses thereof |
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| US (3) | US9381228B2 (OSRAM) |
| EP (1) | EP2040728B1 (OSRAM) |
| JP (1) | JP5474535B2 (OSRAM) |
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| AU (1) | AU2007255196B2 (OSRAM) |
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| DK (1) | DK2040728T3 (OSRAM) |
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| SI (1) | SI2040728T1 (OSRAM) |
| WO (1) | WO2007141533A2 (OSRAM) |
| ZA (1) | ZA200810323B (OSRAM) |
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| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
| SI1680443T1 (sl) | 2003-11-05 | 2014-01-31 | Dana-Farber Cancer Institute, Inc. | Stabilizirani peptidi z alfa vijačnico in uporabe le-teh |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| PT2118123E (pt) | 2007-01-31 | 2016-02-10 | Harvard College | Péptidos de p53 estabilizados e suas utilizações |
| JP5631201B2 (ja) | 2007-03-28 | 2014-11-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ステッチングされたポリペプチド |
| GB0724393D0 (en) * | 2007-12-14 | 2008-01-23 | Univ Ulster | Use of FKBPL gene to identify a cause of infertility |
| WO2010011313A2 (en) | 2008-07-23 | 2010-01-28 | President And Fellows Of Harvard College | Ligation of stapled polypeptides |
| JP2012503025A (ja) | 2008-09-22 | 2012-02-02 | エルロン・セラピューティクス・インコーポレイテッド | 精製されたポリペプチド組成物を調製するための方法 |
| EP2376100B1 (en) | 2009-01-14 | 2017-10-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| GB0908589D0 (en) * | 2009-05-19 | 2009-06-24 | Univ Belfast | Assay method |
| EP2453908B1 (en) | 2009-07-13 | 2018-03-14 | President and Fellows of Harvard College | Bifunctional stapled polypeptides and uses thereof |
| WO2011038049A1 (en) | 2009-09-22 | 2011-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| MX355543B (es) | 2010-08-13 | 2018-04-20 | Aileron Therapeutics Inc Star | Macrociclos peptidomiméticos. |
| WO2012040459A2 (en) | 2010-09-22 | 2012-03-29 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
| WO2012174423A1 (en) | 2011-06-17 | 2012-12-20 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of rab gtpase function |
| WO2013052803A2 (en) | 2011-10-07 | 2013-04-11 | Radiorx, Inc. | Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products |
| TWI643868B (zh) | 2011-10-18 | 2018-12-11 | 艾利倫治療公司 | 擬肽巨環化合物 |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER |
| SG11201404648PA (en) | 2012-02-15 | 2014-09-26 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| SMT202100337T1 (it) | 2012-09-26 | 2021-07-12 | Harvard College | Peptidi graffati bloccati con prolina e loro usi |
| KR20150082307A (ko) | 2012-11-01 | 2015-07-15 | 에일러론 테라퓨틱스 인코포레이티드 | 이치환 아미노산 및 이의 제조 및 사용 방법 |
| BR112015022872A2 (pt) | 2013-03-13 | 2017-11-07 | Harvard College | polipeptídeos grampeados e costurados, seu uso, seu método de preparação, composição que os compreende e aminoácido |
| AU2014278005B2 (en) | 2013-06-14 | 2018-11-22 | President And Fellows Of Harvard College | Stabilized polypeptide insulin receptor modulators |
| CA2949535C (en) | 2014-05-21 | 2023-09-12 | President And Fellows Of Harvard College | Ras inhibitory peptides and uses thereof |
| EP3197477A4 (en) | 2014-09-24 | 2018-07-04 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| SG11201702223UA (en) | 2014-09-24 | 2017-04-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| KR20170129879A (ko) | 2015-03-20 | 2017-11-27 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| JP2018528217A (ja) | 2015-09-10 | 2018-09-27 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | Ｍｃｌ−１のモジュレーターとしてのペプチド模倣大環状分子 |
| US10342778B1 (en) | 2015-10-20 | 2019-07-09 | Epicentrx, Inc. | Treatment of brain metastases using organonitro compound combination therapy |
| US9987270B1 (en) | 2015-10-29 | 2018-06-05 | Epicentrix, Inc. | Treatment of gliomas using organonitro compound combination therapy |
| AU2017207304B2 (en) | 2016-01-11 | 2022-05-26 | Epicentrx, Inc. | Compositions and methods for intravenous administration of 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone |
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Also Published As
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| PL2040728T3 (pl) | 2016-02-29 |
| NZ573425A (en) | 2012-07-27 |
| GB0611405D0 (en) | 2006-07-19 |
| IL195580A0 (en) | 2011-08-01 |
| US20160340402A1 (en) | 2016-11-24 |
| JP2009539367A (ja) | 2009-11-19 |
| HUE028099T2 (en) | 2016-11-28 |
| WO2007141533A2 (en) | 2007-12-13 |
| JP5474535B2 (ja) | 2014-04-16 |
| WO2007141533A3 (en) | 2008-07-31 |
| AU2007255196A1 (en) | 2007-12-13 |
| US9381228B2 (en) | 2016-07-05 |
| EP2040728A2 (en) | 2009-04-01 |
| PT2040728E (pt) | 2015-10-29 |
| EP2040728B1 (en) | 2015-09-02 |
| CN101489575A (zh) | 2009-07-22 |
| CA2657947A1 (en) | 2007-12-13 |
| CY1116970T1 (el) | 2017-04-05 |
| CN101489575B (zh) | 2013-08-28 |
| IL195580A (en) | 2013-07-31 |
| DK2040728T3 (en) | 2015-10-26 |
| SI2040728T1 (sl) | 2015-12-31 |
| CA2657947C (en) | 2017-11-21 |
| ES2548332T3 (es) | 2015-10-15 |
| ZA200810323B (en) | 2013-05-29 |
| US10577406B2 (en) | 2020-03-03 |
| US20090192085A1 (en) | 2009-07-30 |
| US20160340401A1 (en) | 2016-11-24 |
| NZ600690A (en) | 2014-03-28 |
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