CA2631236A1 - Methodes et appareils pour identifier des biomarqueurs de reponse a un traitement et leur utilisation pour predire l'efficacite d'un traitement - Google Patents
Methodes et appareils pour identifier des biomarqueurs de reponse a un traitement et leur utilisation pour predire l'efficacite d'un traitement Download PDFInfo
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- CA2631236A1 CA2631236A1 CA002631236A CA2631236A CA2631236A1 CA 2631236 A1 CA2631236 A1 CA 2631236A1 CA 002631236 A CA002631236 A CA 002631236A CA 2631236 A CA2631236 A CA 2631236A CA 2631236 A1 CA2631236 A1 CA 2631236A1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Proteomics, Peptides & Aminoacids (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
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- Oncology (AREA)
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- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention a pour objet des méthodes et des appareils pour prédire la sensibilité d'un patient à un composé ou à un traitement médical. L'invention concerne aussi des méthodes pour identifier des biomarqueurs de gène dont l'expression correspond à une sensibilité ou une résistance à un traitement dans une population ou sous-population de patients.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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DKPA200501696 | 2005-12-01 | ||
DKPA200501696 | 2005-12-01 | ||
PCT/IB2006/004048 WO2007072225A2 (fr) | 2005-12-01 | 2006-12-01 | Méthodes et appareils pour identifier des biomarqueurs de réponse à un traitement et leur utilisation pour prédire l'efficacité d’un traitement |
Publications (2)
Publication Number | Publication Date |
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CA2631236A1 true CA2631236A1 (fr) | 2007-06-28 |
CA2631236C CA2631236C (fr) | 2019-10-29 |
Family
ID=38189039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2631236A Active CA2631236C (fr) | 2005-12-01 | 2006-12-01 | Methodes et appareils pour identifier des biomarqueurs de reponse a un traitement et leur utilisation pour predire l'efficacite d'un traitement |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1960551A2 (fr) |
JP (3) | JP5984324B2 (fr) |
CN (1) | CN101365806B (fr) |
CA (1) | CA2631236C (fr) |
WO (1) | WO2007072225A2 (fr) |
Cited By (4)
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US10181008B2 (en) | 2013-05-30 | 2019-01-15 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
US10892038B2 (en) | 2010-01-11 | 2021-01-12 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
EP3674416A4 (fr) * | 2017-09-29 | 2021-05-26 | Kyushu University, National University Corporation | Procédé et kit de prédiction de l'efficacité thérapeutique d'une chimiothérapie pour des patients atteints d'un lymphome diffus à grandes cellules b |
CN113593700A (zh) * | 2021-08-06 | 2021-11-02 | 江苏师范大学 | 分析肺癌进展的方法、装置、设备、介质及程序产品 |
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JP2010535518A (ja) * | 2007-08-14 | 2010-11-25 | エフ.ホフマン−ラ ロシュ アーゲー | Egfr阻害剤治療のための予測マーカー |
ES2605237T3 (es) * | 2007-09-17 | 2017-03-13 | Mdxhealth Sa | Novedosos marcadores para la detección del cáncer de vejiga |
JP5592793B2 (ja) * | 2008-08-29 | 2014-09-17 | 学校法人北里研究所 | Dnaメチル化阻害剤の薬剤効果検出方法 |
GB0816867D0 (en) * | 2008-09-15 | 2008-10-22 | Glaxosmithkline Biolog Sa | Method |
SG10201402288RA (en) | 2009-05-11 | 2014-07-30 | Berg Llc | Methods for the diagnosis of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
TW201136604A (en) | 2009-12-14 | 2011-11-01 | Oncotherapy Science Inc | TMEM22 peptides and vaccines including the same |
KR101853511B1 (ko) * | 2009-12-31 | 2018-06-20 | 큐알엔에이, 인크. | 인슐린 수용체 기질 2 및 전사 인자 e3(tfe3)에 대한 천연 안티센스 전사체의 억제에 의한 irs2 관련된 질환의 치료 |
AU2011246976B2 (en) | 2010-04-29 | 2016-01-28 | Allarity Therapeutics Europe ApS | Methods and devices for predicting treatment efficacy |
TR201903026T4 (tr) | 2010-06-14 | 2019-04-22 | Lykera Biomed S A | S100a4 anti̇korlari ve bunlarin terapöti̇k kullanimlari. |
CA2841142C (fr) | 2010-06-23 | 2020-12-15 | Ryan D. Morin | Biomarqueurs pour lymphomes non hodgkiniens et leurs utilisations |
SG10201505769PA (en) | 2010-07-27 | 2015-09-29 | Genomic Health Inc | Method for using gene expression to determine prognosis of prostate cancer |
US9175331B2 (en) | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
KR102061353B1 (ko) * | 2010-09-10 | 2020-01-02 | 에피자임, 인코포레이티드 | 인간 ezh2의 억제제 및 이의 사용 방법 |
CN102408478A (zh) * | 2010-09-21 | 2012-04-11 | 复旦大学 | 一种人少突神经胶质瘤标志物map2蛋白及其用途 |
AU2011343954A1 (en) * | 2010-12-15 | 2013-07-11 | Medimmune, Llc | Melanoma treatments |
PT2666015T (pt) * | 2011-01-21 | 2017-03-22 | Basilea Pharmaceutica Ag | Utilização de estatmina como um biomarcador da resposta farmacológica a furazanobenzimidazolos |
CN103608323B (zh) | 2011-04-04 | 2016-08-17 | 博格有限责任公司 | 治疗中枢神经系统肿瘤的方法 |
JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
KR101439856B1 (ko) * | 2011-06-02 | 2014-09-17 | 한국생명공학연구원 | 항-atic 자가면역항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물 |
CN104024851A (zh) * | 2011-11-28 | 2014-09-03 | 加拿大国家研究委员会 | 针对癌症的紫杉醇反应标志物 |
EP2809812A4 (fr) | 2012-01-31 | 2016-01-27 | Genomic Health Inc | Algorithme de profil d'expression génique et test de détermination du pronostic du cancer de la prostate |
WO2013158984A1 (fr) | 2012-04-19 | 2013-10-24 | Acetylon Pharmaceuticals, Inc. | Biomarqueurs permettant d'identifier des patients qui réagiront à un traitement, et traitement desdits patients |
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US11242564B2 (en) * | 2012-07-12 | 2022-02-08 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes |
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JP2004043446A (ja) * | 2002-05-15 | 2004-02-12 | Schering Ag | ヒストンデアセチラーゼ抑制剤及びその使用 |
EP2272512A1 (fr) * | 2002-05-17 | 2011-01-12 | Celgene Corporation | Compositions pharmaceutiques pour le traitement du cancer |
JP2007501608A (ja) * | 2003-08-08 | 2007-02-01 | 株式会社 キャンバス | 抗癌治療の効力を推定するための感受性試験 |
US20080113344A1 (en) * | 2003-10-28 | 2008-05-15 | Ralph Wirtz | Methods and Compositions for the Response Prediction of Malignant Neoplasia to Treatment |
US20050147978A1 (en) * | 2003-12-30 | 2005-07-07 | Jose Remacle | Method for quantitative determination of multi-drug resistance in tumors |
US7700280B2 (en) * | 2003-12-31 | 2010-04-20 | The Penn State Research Foundation | Methods for assessing cisplatin resistance, disease progression, and treatment efficacy in ovarian cancer |
US20070270488A1 (en) * | 2004-03-12 | 2007-11-22 | The Queen's University Of Belfast | Treatment and Assays |
CN1972703A (zh) * | 2004-03-30 | 2007-05-30 | 丹麦皇家兽医和农业学院 | 通过阻断和检测蛋白酶抑制剂改进癌症的治疗和癌症治疗效率的预测 |
AU2005233593B2 (en) * | 2004-04-09 | 2010-08-26 | Fondazione Irccs Istituto Nazionale Dei Tumori | Gene expression markers for predicting response to chemotherapy |
-
2006
- 2006-12-01 CN CN200680052220.2A patent/CN101365806B/zh active Active
- 2006-12-01 EP EP06848658A patent/EP1960551A2/fr not_active Withdrawn
- 2006-12-01 WO PCT/IB2006/004048 patent/WO2007072225A2/fr active Application Filing
- 2006-12-01 JP JP2008542865A patent/JP5984324B2/ja active Active
- 2006-12-01 CA CA2631236A patent/CA2631236C/fr active Active
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2014
- 2014-02-19 JP JP2014029461A patent/JP2014147386A/ja active Pending
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2015
- 2015-09-17 JP JP2015183600A patent/JP2016026496A/ja active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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US10892038B2 (en) | 2010-01-11 | 2021-01-12 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
US11776664B2 (en) | 2010-01-11 | 2023-10-03 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
US10181008B2 (en) | 2013-05-30 | 2019-01-15 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
US11551782B2 (en) | 2013-05-30 | 2023-01-10 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
EP3674416A4 (fr) * | 2017-09-29 | 2021-05-26 | Kyushu University, National University Corporation | Procédé et kit de prédiction de l'efficacité thérapeutique d'une chimiothérapie pour des patients atteints d'un lymphome diffus à grandes cellules b |
CN113593700A (zh) * | 2021-08-06 | 2021-11-02 | 江苏师范大学 | 分析肺癌进展的方法、装置、设备、介质及程序产品 |
CN113593700B (zh) * | 2021-08-06 | 2024-02-27 | 江苏师范大学 | 分析肺癌进展的方法、装置、设备、介质及程序产品 |
Also Published As
Publication number | Publication date |
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CN101365806A (zh) | 2009-02-11 |
WO2007072225A3 (fr) | 2008-07-10 |
EP1960551A2 (fr) | 2008-08-27 |
JP2016026496A (ja) | 2016-02-18 |
JP5984324B2 (ja) | 2016-09-06 |
CN101365806B (zh) | 2016-11-16 |
JP2009523011A (ja) | 2009-06-18 |
JP2014147386A (ja) | 2014-08-21 |
WO2007072225A8 (fr) | 2008-11-06 |
WO2007072225A2 (fr) | 2007-06-28 |
CA2631236C (fr) | 2019-10-29 |
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