CA2613111C - Microneedle array applicator device and method of array application - Google Patents
Microneedle array applicator device and method of array application Download PDFInfo
- Publication number
- CA2613111C CA2613111C CA2613111A CA2613111A CA2613111C CA 2613111 C CA2613111 C CA 2613111C CA 2613111 A CA2613111 A CA 2613111A CA 2613111 A CA2613111 A CA 2613111A CA 2613111 C CA2613111 C CA 2613111C
- Authority
- CA
- Canada
- Prior art keywords
- application device
- patch
- impactor
- microneedle array
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title description 11
- 230000003116 impacting effect Effects 0.000 claims abstract description 6
- 230000007246 mechanism Effects 0.000 claims description 19
- 230000001133 acceleration Effects 0.000 claims description 17
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 238000005381 potential energy Methods 0.000 claims description 3
- 210000003491 skin Anatomy 0.000 description 41
- 238000003491 array Methods 0.000 description 20
- 239000003814 drug Substances 0.000 description 10
- 230000037317 transdermal delivery Effects 0.000 description 9
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 210000000434 stratum corneum Anatomy 0.000 description 6
- 229940079593 drug Drugs 0.000 description 5
- 229940124597 therapeutic agent Drugs 0.000 description 5
- 238000013461 design Methods 0.000 description 4
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- 230000002708 enhancing effect Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 150000002605 large molecules Chemical class 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000002493 microarray Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 239000002831 pharmacologic agent Substances 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 229940122361 Bisphosphonate Drugs 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 229940021995 DNA vaccine Drugs 0.000 description 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 229910000639 Spring steel Inorganic materials 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- DCSBSVSZJRSITC-UHFFFAOYSA-M alendronate sodium trihydrate Chemical compound O.O.O.[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O DCSBSVSZJRSITC-UHFFFAOYSA-M 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 150000004663 bisphosphonates Chemical class 0.000 description 1
- 229960004755 ceftriaxone Drugs 0.000 description 1
- VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
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- 239000011888 foil Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
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- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
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- 238000013268 sustained release Methods 0.000 description 1
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- 230000000699 topical effect Effects 0.000 description 1
- 238000013271 transdermal drug delivery Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1585—Needle inserters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69444705P | 2005-06-27 | 2005-06-27 | |
| US60/694,447 | 2005-06-27 | ||
| US74629806P | 2006-05-03 | 2006-05-03 | |
| US60/746,298 | 2006-05-03 | ||
| PCT/US2006/024671 WO2007002521A2 (en) | 2005-06-27 | 2006-06-23 | Microneedle array applicator device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2613111A1 CA2613111A1 (en) | 2007-01-04 |
| CA2613111C true CA2613111C (en) | 2015-05-26 |
Family
ID=37054466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2613111A Expired - Fee Related CA2613111C (en) | 2005-06-27 | 2006-06-23 | Microneedle array applicator device and method of array application |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8784363B2 (enExample) |
| EP (2) | EP2474338B1 (enExample) |
| JP (1) | JP5144510B2 (enExample) |
| CN (1) | CN101208130B (enExample) |
| AU (1) | AU2006261898B2 (enExample) |
| CA (1) | CA2613111C (enExample) |
| WO (1) | WO2007002521A2 (enExample) |
Families Citing this family (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| BRPI0517749A (pt) * | 2004-11-18 | 2008-10-21 | 3M Innovative Properties Co | dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação |
| JP5301985B2 (ja) | 2005-04-07 | 2013-09-25 | スリーエム イノベイティブ プロパティズ カンパニー | ツールフィードバック感知のためのシステム及び方法 |
| ATE477833T1 (de) | 2005-06-27 | 2010-09-15 | 3M Innovative Properties Co | Mikronadelkartuschenanordnung |
| WO2007124411A1 (en) | 2006-04-20 | 2007-11-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
| GB2448493B (en) | 2007-04-16 | 2009-10-14 | Dewan Fazlul Hoque Chowdhury | Microneedle transdermal delivery device |
| US9114238B2 (en) | 2007-04-16 | 2015-08-25 | Corium International, Inc. | Solvent-cast microprotrusion arrays containing active ingredient |
| WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
| WO2009079712A1 (en) | 2007-12-24 | 2009-07-02 | The University Of Queensland | Coating method |
| CN102007066B (zh) | 2008-02-07 | 2013-06-26 | 昆士兰大学 | 贴片制造 |
| CA2760680A1 (en) | 2008-05-23 | 2009-11-26 | The University Of Queensland | Analyte detection by microneedle patch with analyte selective reagents |
| CN105999538A (zh) | 2008-11-18 | 2016-10-12 | 3M创新有限公司 | 空心微针阵列和方法 |
| EP2399643A4 (en) | 2009-02-23 | 2012-08-22 | Medrx Co Ltd | APPLICATOR FOR MICRO NEEDLE NETWORK |
| US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
| EP2408372B1 (en) | 2009-03-02 | 2019-01-09 | Seventh Sense Biosystems, Inc. | Devices associated with blood sampling |
| US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
| US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
| US10010706B2 (en) * | 2009-07-31 | 2018-07-03 | 3M Innovative Properties Company | Hollow microneedle arrays |
| JP5663792B2 (ja) * | 2009-08-07 | 2015-02-04 | 株式会社 メドレックス | 剣山型マイクロニードルのアプリケータデバイス |
| WO2011089907A1 (ja) | 2010-01-22 | 2011-07-28 | 株式会社メドレックス | マイクロニードル貼付剤の貼付補助具 |
| GB201007207D0 (en) * | 2010-04-29 | 2010-06-16 | Univ Cork | Method |
| US9687641B2 (en) | 2010-05-04 | 2017-06-27 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
| AU2011248166B2 (en) * | 2010-05-04 | 2015-12-17 | Corium Pharma Solutions, Inc. | Applicators for microneedles |
| JP5562138B2 (ja) | 2010-06-24 | 2014-07-30 | シスメックス株式会社 | 微細孔形成装置 |
| WO2012006677A1 (en) * | 2010-07-14 | 2012-01-19 | The University Of Queensland | Patch applying apparatus |
| ES2561824T3 (es) | 2010-07-16 | 2016-03-01 | Seventh Sense Biosystems, Inc. | Ambiente a baja presión para dispositivos de transferencia de fluidos |
| US20130158482A1 (en) | 2010-07-26 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
| US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
| WO2012048285A1 (en) * | 2010-10-08 | 2012-04-12 | Lanco Biosciences, Inc. | Delivery of bisphosphonates by microinjection systems |
| ES2565805T3 (es) | 2010-11-09 | 2016-04-07 | Seventh Sense Biosystems, Inc. | Sistemas e interfaces para el muestreo de sangre |
| US8814831B2 (en) | 2010-11-30 | 2014-08-26 | Becton, Dickinson And Company | Ballistic microneedle infusion device |
| US8795234B2 (en) | 2010-11-30 | 2014-08-05 | Becton, Dickinson And Company | Integrated spring-activated ballistic insertion for drug infusion device |
| US9950109B2 (en) | 2010-11-30 | 2018-04-24 | Becton, Dickinson And Company | Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion |
| WO2012075209A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of triptans by microinjection systems |
| WO2012075339A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of heparins by microinjection systems |
| WO2012075375A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of parathyroid hormones by microinjection systems |
| US20120143119A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of Serotonin Receptor Antagonists By Microinjection Systems |
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| KR102237667B1 (ko) | 2011-04-29 | 2021-04-12 | 세븐쓰 센스 바이오시스템즈, 인크. | 유체들의 전달 및/또는 수용 |
| JP6411888B2 (ja) * | 2011-09-07 | 2018-10-24 | スリーエム イノベイティブ プロパティズ カンパニー | 中空マイクロニードルアレイのための送達システム |
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| JP6126105B2 (ja) * | 2011-10-12 | 2017-05-10 | スリーエム イノベイティブ プロパティズ カンパニー | 一体化されたマイクロニードル送達システム |
| IN2014CN02637A (enExample) * | 2011-10-12 | 2015-08-07 | 3M Innovative Properties Co | |
| EP2765927B1 (en) | 2011-10-12 | 2021-02-24 | Vaxxas Pty Limited | Delivery device |
| USD692997S1 (en) | 2011-11-08 | 2013-11-05 | Becton Dickinson France, S.A.S. | Microinfuser |
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| JP6865524B2 (ja) | 2012-12-21 | 2021-04-28 | コリウム， インコーポレイテッド | 治療剤を送達するためのマイクロアレイおよび使用方法 |
| EP3513833A1 (en) * | 2012-12-21 | 2019-07-24 | 3M Innovative Properties Co. | Adhesive assemblies and microneedle injection apparatus comprising same |
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| CN115923337A (zh) | 2017-03-31 | 2023-04-07 | 瓦克萨斯私人有限公司 | 用于涂覆表面的设备和方法 |
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2006
- 2006-06-23 CA CA2613111A patent/CA2613111C/en not_active Expired - Fee Related
- 2006-06-23 AU AU2006261898A patent/AU2006261898B2/en not_active Ceased
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| JP5144510B2 (ja) | 2013-02-13 |
| CN101208130B (zh) | 2012-05-16 |
| AU2006261898A1 (en) | 2007-01-04 |
| US20100222743A1 (en) | 2010-09-02 |
| EP1901799A2 (en) | 2008-03-26 |
| US9789249B2 (en) | 2017-10-17 |
| JP2008543527A (ja) | 2008-12-04 |
| EP1901799B1 (en) | 2012-06-13 |
| EP2474338A1 (en) | 2012-07-11 |
| WO2007002521A3 (en) | 2007-06-21 |
| CA2613111A1 (en) | 2007-01-04 |
| CN101208130A (zh) | 2008-06-25 |
| WO2007002521A2 (en) | 2007-01-04 |
| AU2006261898B2 (en) | 2011-11-03 |
| US20140330209A1 (en) | 2014-11-06 |
| EP2474338B1 (en) | 2013-07-24 |
| US8784363B2 (en) | 2014-07-22 |
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