CA2606087A1 - Novel oxadiazole derivatives and their medical use - Google Patents
Novel oxadiazole derivatives and their medical use Download PDFInfo
- Publication number
- CA2606087A1 CA2606087A1 CA002606087A CA2606087A CA2606087A1 CA 2606087 A1 CA2606087 A1 CA 2606087A1 CA 002606087 A CA002606087 A CA 002606087A CA 2606087 A CA2606087 A CA 2606087A CA 2606087 A1 CA2606087 A1 CA 2606087A1
- Authority
- CA
- Canada
- Prior art keywords
- nitro
- oxadiazol
- phenyl
- pyridine
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 125000000217 alkyl group Chemical group 0.000 claims description 52
- 125000005843 halogen group Chemical group 0.000 claims description 48
- 125000001188 haloalkyl group Chemical group 0.000 claims description 47
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 47
- 125000003118 aryl group Chemical group 0.000 claims description 45
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 45
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- 125000003545 alkoxy group Chemical group 0.000 claims description 37
- 125000002541 furyl group Chemical group 0.000 claims description 37
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 33
- 125000001544 thienyl group Chemical group 0.000 claims description 31
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67471105P | 2005-04-26 | 2005-04-26 | |
| DKPA200500612 | 2005-04-26 | ||
| US60/674,711 | 2005-04-26 | ||
| DKPA200500612 | 2005-04-26 | ||
| PCT/EP2006/061773 WO2006114400A1 (en) | 2005-04-26 | 2006-04-24 | Novel oxadiazole derivatives and their medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2606087A1 true CA2606087A1 (en) | 2006-11-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002606087A Abandoned CA2606087A1 (en) | 2005-04-26 | 2006-04-24 | Novel oxadiazole derivatives and their medical use |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8017631B2 (https=) |
| EP (1) | EP1881979B1 (https=) |
| JP (1) | JP2008539195A (https=) |
| KR (1) | KR20080000622A (https=) |
| AT (1) | ATE477253T1 (https=) |
| AU (1) | AU2006239418A1 (https=) |
| CA (1) | CA2606087A1 (https=) |
| IL (1) | IL186360A0 (https=) |
| MX (1) | MX2007013263A (https=) |
| NO (1) | NO20076036L (https=) |
| RU (1) | RU2007139255A (https=) |
| WO (1) | WO2006114400A1 (https=) |
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| US7790757B2 (en) | 1998-06-16 | 2010-09-07 | Targacept, Inc. | Compounds capable of activating cholinergic receptors |
| US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| US7459469B2 (en) | 2004-11-10 | 2008-12-02 | Targacept, Inc. | Hydroxybenzoate salts of metanicotine compounds |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| PL1907382T3 (pl) | 2005-07-26 | 2016-01-29 | Bial Portela & Ca Sa | Pochodne nitrokatecholowe jako inhibitory COMT |
| EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
| WO2008028903A2 (en) * | 2006-09-04 | 2008-03-13 | Neurosearch A/S | Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer |
| PT2069336E (pt) | 2006-09-07 | 2013-03-07 | Actelion Pharmaceuticals Ltd | Derivados de piridin-4-ilo como agentes imunomoduladores |
| AR061841A1 (es) | 2006-09-07 | 2008-09-24 | Actelion Pharmaceuticals Ltd | Derivados de tiofen-oxadiazoles, agonistas del receptor s1p1/edg1, composiciones farmaceuticas que los contienen y usos como agentes inmunomoduladores. |
| PL2069335T3 (pl) | 2006-09-08 | 2013-05-31 | Actelion Pharmaceuticals Ltd | Pochodne pirydyn-3-ylu jako środki immunomodulujące |
| ES2393412T3 (es) | 2006-09-21 | 2012-12-21 | Actelion Pharmaceuticals Ltd. | Derivados de fenilo y su uso como inmunomoduladores |
| DE102006050516A1 (de) * | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dihydropyrazolone und ihre Verwendung |
| US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
| US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| UY30846A1 (es) * | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
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| FR2832712B1 (fr) | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique |
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| EP1697333A4 (en) | 2003-12-17 | 2009-07-08 | Merck & Co Inc | (3,4-DISUBSTITUTED) PROPANE ACID BOXYLATES AS AGONISTS OF THE S1P (EDG) RECEPTOR |
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- 2006-04-24 US US11/919,146 patent/US8017631B2/en not_active Expired - Fee Related
- 2006-04-24 RU RU2007139255/04A patent/RU2007139255A/ru not_active Application Discontinuation
- 2006-04-24 JP JP2008508201A patent/JP2008539195A/ja active Pending
- 2006-04-24 EP EP06754801A patent/EP1881979B1/en not_active Expired - Lifetime
- 2006-04-24 WO PCT/EP2006/061773 patent/WO2006114400A1/en not_active Ceased
- 2006-04-24 KR KR1020077024814A patent/KR20080000622A/ko not_active Withdrawn
- 2006-04-24 AU AU2006239418A patent/AU2006239418A1/en not_active Abandoned
- 2006-04-24 AT AT06754801T patent/ATE477253T1/de not_active IP Right Cessation
- 2006-04-24 MX MX2007013263A patent/MX2007013263A/es not_active Application Discontinuation
- 2006-04-24 CA CA002606087A patent/CA2606087A1/en not_active Abandoned
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2007
- 2007-10-07 IL IL186360A patent/IL186360A0/en unknown
- 2007-11-23 NO NO20076036A patent/NO20076036L/no not_active Application Discontinuation
-
2011
- 2011-07-29 US US13/194,193 patent/US20110294856A1/en not_active Abandoned
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|---|---|
| MX2007013263A (es) | 2008-01-22 |
| US20090312347A1 (en) | 2009-12-17 |
| US8017631B2 (en) | 2011-09-13 |
| US20110294856A1 (en) | 2011-12-01 |
| EP1881979B1 (en) | 2010-08-11 |
| EP1881979A1 (en) | 2008-01-30 |
| NO20076036L (no) | 2007-11-23 |
| WO2006114400A1 (en) | 2006-11-02 |
| ATE477253T1 (de) | 2010-08-15 |
| AU2006239418A1 (en) | 2006-11-02 |
| KR20080000622A (ko) | 2008-01-02 |
| IL186360A0 (en) | 2008-01-20 |
| JP2008539195A (ja) | 2008-11-13 |
| RU2007139255A (ru) | 2009-06-10 |
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| FZDE | Discontinued | ||
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