CA2585557C - Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors - Google Patents

Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors Download PDF

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Publication number
CA2585557C
CA2585557C CA002585557A CA2585557A CA2585557C CA 2585557 C CA2585557 C CA 2585557C CA 002585557 A CA002585557 A CA 002585557A CA 2585557 A CA2585557 A CA 2585557A CA 2585557 C CA2585557 C CA 2585557C
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Canada
Prior art keywords
ethyl
pyrimidin
pyrazolo
amine
ethoxyethyl
Prior art date
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Expired - Fee Related
Application number
CA002585557A
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English (en)
French (fr)
Other versions
CA2585557A1 (en
Inventor
Brad Alan Acker
Robert Owen Hughes
Eric John Jacobsen
Hwang-Fun Lu
Thomas Edward Rogers
Michael Brent Tollefson
John Keith Walker
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Pharmacia and Upjohn Co LLC
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Pharmacia and Upjohn Co LLC
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Publication of CA2585557A1 publication Critical patent/CA2585557A1/en
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Publication of CA2585557C publication Critical patent/CA2585557C/en
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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CA002585557A 2004-10-28 2005-10-17 Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors Expired - Fee Related CA2585557C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62294104P 2004-10-28 2004-10-28
US60/622,941 2004-10-28
PCT/IB2005/003326 WO2006046135A2 (en) 2004-10-28 2005-10-17 Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors

Publications (2)

Publication Number Publication Date
CA2585557A1 CA2585557A1 (en) 2006-05-04
CA2585557C true CA2585557C (en) 2009-08-18

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CA002585557A Expired - Fee Related CA2585557C (en) 2004-10-28 2005-10-17 Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5 inhibitors

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EP (1) EP1809632A2 (de)
JP (1) JP2008517994A (de)
CA (1) CA2585557C (de)
WO (1) WO2006046135A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1881985B1 (de) 2005-05-12 2010-12-29 Pfizer, Inc. Wasserfreie kristalline formen von n-[1,2-ethoxyethyl)-5-(n-ethyl-n-methylamino]-7-(4-methylpyridin-2-yl-amino]-1h-pyrazolo[4,3-d]pyrimidin-3-carbonyl]methansulfonsäureamid
NL2000291C2 (nl) * 2005-11-10 2009-02-17 Pfizer Prod Inc 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
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