CA2583803C - Immunogenic and therapeutic compositions for streptococcus pyogenes - Google Patents

Immunogenic and therapeutic compositions for streptococcus pyogenes Download PDF

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Publication number
CA2583803C
CA2583803C CA2583803A CA2583803A CA2583803C CA 2583803 C CA2583803 C CA 2583803C CA 2583803 A CA2583803 A CA 2583803A CA 2583803 A CA2583803 A CA 2583803A CA 2583803 C CA2583803 C CA 2583803C
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CA
Canada
Prior art keywords
fragment
antigens
full
gas
length
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2583803A
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English (en)
French (fr)
Other versions
CA2583803A1 (en
Inventor
Giuliano Bensi
Guido Grandi
Nathalie Norais
Manuel Rodriguez J. Ortega
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GSK Vaccines SRL
Original Assignee
Novartis Vaccines and Diagnostics SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Publication of CA2583803A1 publication Critical patent/CA2583803A1/en
Application granted granted Critical
Publication of CA2583803C publication Critical patent/CA2583803C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2583803A 2004-10-08 2005-10-11 Immunogenic and therapeutic compositions for streptococcus pyogenes Expired - Lifetime CA2583803C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US61685404P 2004-10-08 2004-10-08
US60/616,854 2004-10-08
US65273605P 2005-02-15 2005-02-15
US60/652,736 2005-02-15
US70112105P 2005-07-21 2005-07-21
US60/701,121 2005-07-21
US70520905P 2005-08-04 2005-08-04
US60/705,209 2005-08-04
PCT/US2005/036009 WO2006042027A2 (en) 2004-10-08 2005-10-11 Immunogenic and therapeutic compositions for streptococcus pyogenes

Publications (2)

Publication Number Publication Date
CA2583803A1 CA2583803A1 (en) 2006-04-20
CA2583803C true CA2583803C (en) 2014-11-25

Family

ID=35720938

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2583803A Expired - Lifetime CA2583803C (en) 2004-10-08 2005-10-11 Immunogenic and therapeutic compositions for streptococcus pyogenes

Country Status (6)

Country Link
US (1) US7838010B2 (OSRAM)
EP (1) EP1807446A2 (OSRAM)
JP (2) JP2008544949A (OSRAM)
AU (1) AU2005294275B2 (OSRAM)
CA (1) CA2583803C (OSRAM)
WO (1) WO2006042027A2 (OSRAM)

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EP1648500B1 (en) 2003-07-31 2014-07-09 Novartis Vaccines and Diagnostics, Inc. Immunogenic compositions for streptococcus pyogenes
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
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TWI598360B (zh) * 2016-12-19 2017-09-11 義守大學 Ｆｓｂｍ重組蛋白及其用途
EP3615935A4 (en) * 2017-04-26 2020-12-02 Auckland Uniservices Limited ANALYTICAL AND THERAPEUTIC METHODS, RELATED COMPOSITIONS, AND THEIR USES
CN108379572A (zh) * 2018-01-25 2018-08-10 暨南大学 一种化脓链球菌HtsA蛋白质疫苗以及制备方法和应用
CN110922456B (zh) * 2019-12-28 2023-02-24 重庆艾力彼生物科技有限公司 铜绿假单胞菌疫苗重组蛋白reSBP-ExoU及制备方法和应用
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Also Published As

Publication number Publication date
AU2005294275B2 (en) 2012-09-13
JP2008544949A (ja) 2008-12-11
EP1807446A2 (en) 2007-07-18
CA2583803A1 (en) 2006-04-20
WO2006042027A3 (en) 2006-08-24
US7838010B2 (en) 2010-11-23
WO2006042027A2 (en) 2006-04-20
JP2012126742A (ja) 2012-07-05
AU2005294275A1 (en) 2006-04-20
US20090117113A1 (en) 2009-05-07
WO2006042027A8 (en) 2006-11-02

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