CA2567080A1 - Ice inhibitors for the treatment of autoinflammatory diseases - Google Patents
Ice inhibitors for the treatment of autoinflammatory diseases Download PDFInfo
- Publication number
- CA2567080A1 CA2567080A1 CA002567080A CA2567080A CA2567080A1 CA 2567080 A1 CA2567080 A1 CA 2567080A1 CA 002567080 A CA002567080 A CA 002567080A CA 2567080 A CA2567080 A CA 2567080A CA 2567080 A1 CA2567080 A1 CA 2567080A1
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- ice
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57499304P | 2004-05-27 | 2004-05-27 | |
| US60/574,993 | 2004-05-27 | ||
| PCT/US2005/018949 WO2005117846A2 (en) | 2004-05-27 | 2005-05-27 | Ice inhibitors for the treatment of autoinflammatory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2567080A1 true CA2567080A1 (en) | 2005-12-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002567080A Abandoned CA2567080A1 (en) | 2004-05-27 | 2005-05-27 | Ice inhibitors for the treatment of autoinflammatory diseases |
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| Country | Link |
|---|---|
| US (2) | US7531570B2 (enExample) |
| EP (2) | EP2295054A1 (enExample) |
| JP (1) | JP2008500374A (enExample) |
| CN (1) | CN1980658A (enExample) |
| AU (1) | AU2005249503B2 (enExample) |
| CA (1) | CA2567080A1 (enExample) |
| WO (1) | WO2005117846A2 (enExample) |
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| RU2274642C2 (ru) * | 1998-03-19 | 2006-04-20 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы каспаз |
| PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| CA2566362C (en) * | 2004-05-15 | 2013-09-10 | Vertex Pharmaceuticals Incorporated | Treating seizures using ice inhibitors |
| PL2848258T3 (pl) | 2005-10-26 | 2018-06-29 | Novartis Ag | Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta |
| WO2008100217A1 (en) * | 2007-02-12 | 2008-08-21 | Soederkvist Peter | Polymorphisms in genes of the cryopyrin inflammasome and their uses in the treatment of inflammatory diseases |
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-
2005
- 2005-05-27 US US11/140,649 patent/US7531570B2/en not_active Expired - Lifetime
- 2005-05-27 AU AU2005249503A patent/AU2005249503B2/en not_active Ceased
- 2005-05-27 EP EP10178054A patent/EP2295054A1/en not_active Withdrawn
- 2005-05-27 EP EP05804856A patent/EP1778221A2/en not_active Withdrawn
- 2005-05-27 CN CNA2005800228873A patent/CN1980658A/zh active Pending
- 2005-05-27 JP JP2007515458A patent/JP2008500374A/ja active Pending
- 2005-05-27 WO PCT/US2005/018949 patent/WO2005117846A2/en not_active Ceased
- 2005-05-27 CA CA002567080A patent/CA2567080A1/en not_active Abandoned
-
2009
- 2009-03-25 US US12/410,668 patent/US20090192094A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005117846A2 (en) | 2005-12-15 |
| CN1980658A (zh) | 2007-06-13 |
| JP2008500374A (ja) | 2008-01-10 |
| US20090192094A1 (en) | 2009-07-30 |
| US20050267101A1 (en) | 2005-12-01 |
| WO2005117846A3 (en) | 2006-02-02 |
| AU2005249503A1 (en) | 2005-12-15 |
| EP2295054A1 (en) | 2011-03-16 |
| EP1778221A2 (en) | 2007-05-02 |
| AU2005249503B2 (en) | 2011-08-25 |
| US7531570B2 (en) | 2009-05-12 |
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