CA2565701A1 - Ngal for reduction and amelioration of ischemic and nephrotoxic injuries - Google Patents
Ngal for reduction and amelioration of ischemic and nephrotoxic injuries Download PDFInfo
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- CA2565701A1 CA2565701A1 CA002565701A CA2565701A CA2565701A1 CA 2565701 A1 CA2565701 A1 CA 2565701A1 CA 002565701 A CA002565701 A CA 002565701A CA 2565701 A CA2565701 A CA 2565701A CA 2565701 A1 CA2565701 A1 CA 2565701A1
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- ngal
- kidney
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US56864504P | 2004-05-06 | 2004-05-06 | |
| US60/568,645 | 2004-05-06 | ||
| US61556604P | 2004-10-01 | 2004-10-01 | |
| US60/615,566 | 2004-10-01 | ||
| PCT/US2005/015799 WO2005107793A2 (en) | 2004-05-06 | 2005-05-06 | Ngal for reduction and amelioration of ischemic and nephrotoxic injuries |
Publications (1)
| Publication Number | Publication Date |
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| CA2565701A1 true CA2565701A1 (en) | 2005-11-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA002565701A Abandoned CA2565701A1 (en) | 2004-05-06 | 2005-05-06 | Ngal for reduction and amelioration of ischemic and nephrotoxic injuries |
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| JP (1) | JP2007536260A (enExample) |
| AU (1) | AU2005240190C1 (enExample) |
| CA (1) | CA2565701A1 (enExample) |
| WO (1) | WO2005107793A2 (enExample) |
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| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| RU2584609C2 (ru) * | 2004-09-28 | 2016-05-20 | Кварк Фармасьютикалс, Инк. | Олигорибонуклеотиды и способы их применения для лечения острой почечной недостаточности |
| ES2622467T3 (es) * | 2004-12-20 | 2017-07-06 | Antibodyshop A/S | Determinación de lipocalina asociada a gelatinasa de neutrófilos (NGAL) como marcador diagnóstico para trastornos renales |
| WO2006078717A2 (en) * | 2005-01-19 | 2006-07-27 | Beth Israel Deaconess Medical Center | Lipocalin 2 for the treatment, prevention, and management of cancer metastasis, angiogenesis, and fibrosis |
| US20070037232A1 (en) * | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
| US20080090304A1 (en) * | 2006-10-13 | 2008-04-17 | Barasch Jonathan Matthew | Diagnosis and monitoring of chronic renal disease using ngal |
| US7825099B2 (en) * | 2006-01-20 | 2010-11-02 | Quark Pharmaceuticals, Inc. | Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes |
| JP4865377B2 (ja) | 2006-03-28 | 2012-02-01 | 国立大学法人 新潟大学 | ヒトメガリンの測定方法 |
| US7662578B2 (en) | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
| US20080090765A1 (en) * | 2006-05-25 | 2008-04-17 | The Trustees Of Columbia University In The City Of New York | Compositions for modulating growth of embryonic and adult kidney tissue and uses for treating kidney damage |
| ATE539351T1 (de) | 2006-05-30 | 2012-01-15 | Antibodyshop As | Verfahren zur schnellen beurteilung der schwere eines traumas |
| EP2064553B2 (en) * | 2006-08-07 | 2023-06-07 | Antibodyshop A/S | Diagnostic test to exclude significant renal injury |
| WO2008060607A2 (en) * | 2006-11-14 | 2008-05-22 | Biosite Incorporated | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome |
| EP2095106B1 (en) * | 2006-11-14 | 2013-03-20 | Alere San Diego, Inc. | Methods and compositions for diagnosis and prognosis of renal artery stenosis |
| JP5128828B2 (ja) * | 2007-02-16 | 2013-01-23 | 月桂冠株式会社 | 抗炎症剤及び抗酸化剤 |
| EP2137538B1 (en) * | 2007-03-21 | 2014-04-09 | Bioporto Diagnostics A/s | Diagnostic test for renal injury |
| PT2170403E (pt) * | 2007-06-27 | 2014-07-17 | Quark Pharmaceuticals Inc | Composições e métodos para inibição da expressão de genes pró-apoptóticos |
| US8846036B2 (en) | 2007-10-19 | 2014-09-30 | Abbott Laboratories | Antibodies that bind to mammalian NGAL and uses thereof |
| US8592170B2 (en) * | 2008-03-12 | 2013-11-26 | The Trustees Of Columbia University In The City Of New York | High molecular weight Ngal as a biomarker for chronic kidney disease |
| US8030097B2 (en) * | 2008-04-30 | 2011-10-04 | Versitech Limited and R & C Biogenius Limited | Lipocalin-2 as a prognostic and diagnostic marker for heart and stroke risks |
| BRPI0912683A2 (pt) | 2008-05-15 | 2016-01-26 | Transmolecular Inc | tratamento de tumores metastáticos |
| US20100122355A1 (en) * | 2008-07-16 | 2010-05-13 | Neal Paragas | Transgenic Reporter Mouse and Method for Use |
| US20110268818A1 (en) * | 2008-09-18 | 2011-11-03 | Jonathan Barasch | Ngal-binding siderophores and use thereof to treat iron deficiency and iron overload |
| US20110212104A1 (en) * | 2008-11-03 | 2011-09-01 | Schering Corporation | Inflammatory bowel disease biomarkers and related methods of treatment |
| JP5438770B2 (ja) * | 2008-11-21 | 2014-03-12 | ファディア・アクチボラグ | 急性腎臓損傷を検出またはモニターするための方法、装置およびキット |
| US20100233740A1 (en) * | 2009-02-12 | 2010-09-16 | Jonathan Barasch | Use of urinary ngal to distinguish kidney disease and predict mortality in subjects with cirrhosis |
| US20100233739A1 (en) * | 2009-02-12 | 2010-09-16 | Jonathan Barasch | Use of urinary ngal to diagnose unilateral and bilateral urinary obstruction |
| JP5424702B2 (ja) | 2009-04-27 | 2014-02-26 | 国立大学法人 新潟大学 | 尿中ヒトメガリンを測定することを含む腎疾患検出方法 |
| WO2010126055A1 (ja) * | 2009-04-27 | 2010-11-04 | 国立大学法人新潟大学 | 腎障害の検出用マーカーとしての尿中メガリンの使用 |
| EP2292284B1 (en) * | 2009-09-04 | 2014-02-26 | B. Braun Avitum AG | Kidney substitution treatment machine |
| CN106995493B (zh) | 2010-02-04 | 2021-09-24 | 卫材公司 | 氯毒素多肽和结合物及其应用 |
| WO2011140554A1 (en) * | 2010-05-07 | 2011-11-10 | The Trustees Of Columbia University In The City Of New York | Ngal and urinary tract infection |
| ES2601182T3 (es) | 2010-05-11 | 2017-02-14 | Fred Hutchinson Cancer Research Center | Variantes de clorotoxina, conjugados y métodos para su utilización |
| JP2013529907A (ja) | 2010-05-24 | 2013-07-25 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | Ｎｇａｌタンパク質変異体及びその使用 |
| EP2622095B1 (en) * | 2010-10-01 | 2016-09-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the progression and treating a chronic kidney disease in a patient |
| US20140057838A1 (en) * | 2011-04-11 | 2014-02-27 | The Trustees Of Columbia University In The City Of New York | Osteoblast-expressed lipocalin 2 regulates glucose metabolism |
| US20140163104A1 (en) * | 2011-06-03 | 2014-06-12 | Mcmastedr University | Uses of and methods of treatment with cystathionine |
| WO2014081980A2 (en) | 2012-11-21 | 2014-05-30 | The Trustees Of Columbia University In The City Of New York | Mutant ngal proteins and uses thereof |
| US10156559B2 (en) | 2012-12-10 | 2018-12-18 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| AU2015324103C1 (en) | 2014-09-29 | 2020-08-20 | Fred Hutchinson Cancer Center | Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers |
| JP5866053B1 (ja) * | 2014-12-15 | 2016-02-17 | 株式会社ファンケル | 皮膚粘弾性のマーカー及びその利用 |
| EP3334498B1 (en) | 2015-08-12 | 2023-06-07 | The Trustees of Columbia University in the City of New York | Methods of treating volume depletion and kidney injury |
| HK1258292A1 (zh) | 2015-09-17 | 2019-11-08 | Amgen Inc. | 使用il23途徑生物標誌物預測il23拮抗劑的臨床應答 |
| WO2017096013A1 (en) | 2015-12-01 | 2017-06-08 | Cornell University | Use of mitochondrial iron chelators for treatment of chronic obstructive pulmonary disease |
| RU2018124603A (ru) | 2015-12-22 | 2020-01-24 | Эмджен Инк. | Ccl20 как прогностический фактор клинического ответа на антагонисты ил-23 |
| TWI581802B (zh) * | 2015-12-23 | 2017-05-11 | 國立臺灣師範大學 | 嗜中性白血球膠原蛋白質酶相關疏水性蛋白質之製藥用途 |
| EP3184116B1 (en) * | 2015-12-23 | 2020-09-16 | National Taiwan Normal University | Neutrophil gelatinase-associated lipocalin for use in prevention or treatment of polycystic kidney disease |
| US12048732B2 (en) | 2016-04-15 | 2024-07-30 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
| CA3067911C (en) * | 2017-06-23 | 2024-10-29 | Aki Therapeutics Aps | COMPOSITIONS INTENDED FOR THE PREVENTION AND TREATMENT OF ACUTE KIDNEY INJURY |
| US11298564B2 (en) | 2020-03-10 | 2022-04-12 | Dennis M. Anderson | Medical, surgical and patient lighting apparatus, system, method and controls with pathogen killing electromagnetic radiation |
| CN113075371B (zh) * | 2021-03-22 | 2022-11-18 | 重庆医药高等专科学校 | 一种药物崩解仪 |
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| DE69521813T2 (de) * | 1995-04-12 | 2002-04-11 | Medix Biochemica Ab Kauniainen | Verfahrens und testsätze zur diagnose periodentahlkrankheiten und zur vorhersage des risikos der progression davon |
| SK285461B6 (sk) | 1996-05-24 | 2007-02-01 | Biogen Idec Ma Inc. | Izolovaný polypeptid KIM, modulátor tkanivovej regenerácie a nukleová kyselina, ktorá ho kóduje, spôsob prípravy polypeptidu a farmaceutická kompozícia obsahujúca polypeptid |
| AUPP784398A0 (en) * | 1998-12-21 | 1999-01-21 | Monash University | Kidney disease detection and treatment |
| US6114123A (en) * | 1999-06-14 | 2000-09-05 | Incyte Pharmaceuticals, Inc. | Lipocalin family protein |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| GB0215509D0 (en) * | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
| WO2004006941A1 (en) * | 2002-07-17 | 2004-01-22 | Index Pharmaceuticals Ab | Antisense compounds, methods and compositions for treating ngal-related inflammatory disorders |
| BRPI0408802B8 (pt) * | 2003-03-27 | 2021-07-27 | Childrens Hospital Med Ct | método para a detecção de uma lesão de célula tubular renal isquêmica e método para identificar a extensão desta lesão |
| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
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- 2005-05-06 CA CA002565701A patent/CA2565701A1/en not_active Abandoned
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- 2005-05-06 JP JP2007511623A patent/JP2007536260A/ja not_active Withdrawn
- 2005-05-06 EP EP05749675.4A patent/EP1750500B1/en not_active Expired - Lifetime
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2013
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| AU2005240190B2 (en) | 2011-08-25 |
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| EP2661963A1 (en) | 2013-11-13 |
| US7776824B2 (en) | 2010-08-17 |
| EP1750500B1 (en) | 2015-07-08 |
| JP2007536260A (ja) | 2007-12-13 |
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