CA2555675A1 - Nicotinamide riboside kinase compositions and methods for using the same - Google Patents
Nicotinamide riboside kinase compositions and methods for using the same Download PDFInfo
- Publication number
- CA2555675A1 CA2555675A1 CA002555675A CA2555675A CA2555675A1 CA 2555675 A1 CA2555675 A1 CA 2555675A1 CA 002555675 A CA002555675 A CA 002555675A CA 2555675 A CA2555675 A CA 2555675A CA 2555675 A1 CA2555675 A1 CA 2555675A1
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- Prior art keywords
- nicotinamide riboside
- cell
- nrk
- prodrug
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
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- Hematology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| US54334704P | 2004-02-10 | 2004-02-10 | |
| US60/543,347 | 2004-02-10 | ||
| PCT/US2005/004337 WO2005077091A2 (en) | 2004-02-10 | 2005-02-09 | Nicotinamide riboside kinase compositions and methods for using the same |
Publications (1)
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| CA2555675A1 true CA2555675A1 (en) | 2005-08-25 |
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| CA002555675A Abandoned CA2555675A1 (en) | 2004-02-10 | 2005-02-09 | Nicotinamide riboside kinase compositions and methods for using the same |
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|---|---|
| US (3) | US8197807B2 (https=) |
| EP (1) | EP1723227A4 (https=) |
| JP (1) | JP2007521835A (https=) |
| AU (1) | AU2005211773B2 (https=) |
| CA (1) | CA2555675A1 (https=) |
| WO (1) | WO2005077091A2 (https=) |
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| US8114626B2 (en) * | 2004-02-10 | 2012-02-14 | Trustees Of Dartmouth College | Yeast strain and method for using the same to produce nicotinamide riboside |
| US20050227327A1 (en) * | 2004-02-10 | 2005-10-13 | Brenner Charles M | Nicotinamide riboside kinase compositions and methods for using the same |
| JP2008501343A (ja) * | 2004-06-04 | 2008-01-24 | ワシントン・ユニバーシティ | 神経障害を治療するための方法および組成物 |
| US20070014833A1 (en) * | 2005-03-30 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| US20060229265A1 (en) * | 2005-03-30 | 2006-10-12 | Sirtris Pharmaceuticals, Inc. | Nicotinamide riboside and analogues thereof |
| US20060292099A1 (en) * | 2005-05-25 | 2006-12-28 | Michael Milburn | Treatment of eye disorders with sirtuin modulators |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| EP2124985A4 (en) * | 2007-01-26 | 2011-06-08 | Univ Washington | METHOD AND COMPOSITIONS FOR TREATING NERVOUS ELEMENTS |
| KR20220098049A (ko) | 2013-10-30 | 2022-07-08 | 크로마덱스 아이엔씨. | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| AU2015270090A1 (en) | 2014-06-06 | 2016-12-22 | Glaxosmithkline Intellectual Property (No.2) Limited | Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof |
| US10323058B2 (en) | 2014-07-24 | 2019-06-18 | W. R. Grace & Co.-Conn. | Crystalline form of nicotinamide riboside |
| EP3268379B1 (en) | 2015-03-09 | 2023-11-01 | W.R. Grace & CO. - CONN. | Crystalline form of nicotinamide riboside |
| WO2016149395A1 (en) * | 2015-03-16 | 2016-09-22 | ChromaDex Inc. | Nicotinic acid riboside or nicotinamide riboside compositions, reduced derivatives thereof, and the use thereof |
| JP2018515485A (ja) * | 2015-05-01 | 2018-06-14 | ザ プロクター アンド ギャンブル カンパニー | 皮膚の外観を改善する方法及びニコチンアミドリボシドを使用したそのための組成物 |
| WO2017004102A1 (en) | 2015-06-29 | 2017-01-05 | The Procter & Gamble Company | Multi-component skin care product comprising nicoinamide riboside in a multi-chambered container |
| EP3236928B1 (en) | 2016-01-11 | 2020-12-09 | The Procter and Gamble Company | Method of treating a skin condition and compositions therefor |
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| AU2005211773B2 (en) | 2009-06-25 |
| US20080206221A1 (en) | 2008-08-28 |
| US20070027095A1 (en) | 2007-02-01 |
| JP2007521835A (ja) | 2007-08-09 |
| US8383086B2 (en) | 2013-02-26 |
| WO2005077091A2 (en) | 2005-08-25 |
| AU2005211773A1 (en) | 2005-08-25 |
| EP1723227A2 (en) | 2006-11-22 |
| WO2005077091A8 (en) | 2006-09-14 |
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