CA2555233A1 - A wound healing composition comprising living dermal fibroblast cells and a fibrin support matrix - Google Patents

A wound healing composition comprising living dermal fibroblast cells and a fibrin support matrix Download PDF

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Publication number
CA2555233A1
CA2555233A1 CA002555233A CA2555233A CA2555233A1 CA 2555233 A1 CA2555233 A1 CA 2555233A1 CA 002555233 A CA002555233 A CA 002555233A CA 2555233 A CA2555233 A CA 2555233A CA 2555233 A1 CA2555233 A1 CA 2555233A1
Authority
CA
Canada
Prior art keywords
wound healing
expression
cells
composition
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002555233A
Other languages
English (en)
French (fr)
Inventor
Paul Kemp
Gyorgyi Talas
Jennifer Sutherland
Margaret Batten
Penelope Ann Johnson
Andrew Shering
Michael Mcwhan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew Orthopaedics AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0403226A external-priority patent/GB0403226D0/en
Priority claimed from GB0403220A external-priority patent/GB0403220D0/en
Priority claimed from GB0426252A external-priority patent/GB0426252D0/en
Application filed by Individual filed Critical Individual
Publication of CA2555233A1 publication Critical patent/CA2555233A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33Fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
CA002555233A 2004-02-13 2005-02-14 A wound healing composition comprising living dermal fibroblast cells and a fibrin support matrix Abandoned CA2555233A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB0403226.4 2004-02-13
GB0403226A GB0403226D0 (en) 2004-02-13 2004-02-13 Means of packaging a wound healing composition
GB0403220A GB0403220D0 (en) 2004-02-13 2004-02-13 Wound healing composition
GB0403220.7 2004-02-13
US55615504P 2004-03-25 2004-03-25
US55619404P 2004-03-25 2004-03-25
US60/556,194 2004-03-25
US60/556,155 2004-03-25
GB0426252A GB0426252D0 (en) 2004-11-30 2004-11-30 Wound healing composition
GB0426252.3 2004-11-30
US63242504P 2004-12-01 2004-12-01
US60/632,425 2004-12-01
PCT/GB2005/000511 WO2005079821A1 (en) 2004-02-13 2005-02-14 Wound healing profile

Publications (1)

Publication Number Publication Date
CA2555233A1 true CA2555233A1 (en) 2005-09-01

Family

ID=34891423

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002555233A Abandoned CA2555233A1 (en) 2004-02-13 2005-02-14 A wound healing composition comprising living dermal fibroblast cells and a fibrin support matrix
CA2556098A Expired - Fee Related CA2556098C (en) 2004-02-13 2005-02-14 Wound healing composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2556098A Expired - Fee Related CA2556098C (en) 2004-02-13 2005-02-14 Wound healing composition

Country Status (6)

Country Link
US (3) US8765169B2 (enExample)
EP (2) EP1718317A1 (enExample)
JP (4) JP5706058B2 (enExample)
AU (2) AU2005215213C1 (enExample)
CA (2) CA2555233A1 (enExample)
WO (2) WO2005079821A1 (enExample)

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RU2702152C1 (ru) * 2018-11-15 2019-10-04 Государственное бюджетное учреждение здравоохранения "Научно-исследовательский институт - краевая клиническая больница N 1 имени профессора С.В. Очаповского" Министерства здравоохранения Краснодарского края (ГБУЗ "НИИ-ККБ N 1 им. проф. Очаповского" Минздрава Краснодарского края) Способ лечения донорской раны живота
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CN111614010B (zh) * 2020-05-12 2021-04-13 中国长江电力股份有限公司 500kV焊接型GIL管道母线分解检修方法
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Also Published As

Publication number Publication date
CA2556098A1 (en) 2005-09-01
AU2005215213C1 (en) 2011-04-28
WO2005079822A2 (en) 2005-09-01
WO2005079822A3 (en) 2005-11-03
US9526746B2 (en) 2016-12-27
AU2005215211B2 (en) 2011-11-03
AU2005215211A1 (en) 2005-09-01
JP2015063555A (ja) 2015-04-09
US9248153B2 (en) 2016-02-02
EP1718318A2 (en) 2006-11-08
JP6141603B2 (ja) 2017-06-07
US20140335183A1 (en) 2014-11-13
WO2005079821A1 (en) 2005-09-01
JP6141821B2 (ja) 2017-06-07
EP1718317A1 (en) 2006-11-08
JP2015134815A (ja) 2015-07-27
JP2012192206A (ja) 2012-10-11
US20080193507A1 (en) 2008-08-14
JP2007522195A (ja) 2007-08-09
US20080226720A1 (en) 2008-09-18
JP5706058B2 (ja) 2015-04-22
US8765169B2 (en) 2014-07-01
CA2556098C (en) 2015-11-24
EP1718318B1 (en) 2014-08-13
AU2005215213B2 (en) 2010-09-09
AU2005215213A1 (en) 2005-09-01

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EEER Examination request
FZDE Discontinued

Effective date: 20190214